المؤلفون: Ambrosi TH; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Marecic O; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., McArdle A; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Sinha R; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA., Gulati GS; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA., Tong X; Department of Bioengineering, Stanford University, Stanford, CA, USA., Wang Y; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Steininger HM; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Hoover MY; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Koepke LS; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Murphy MP; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Sokol J; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Seo EY; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Tevlin R; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Lopez M; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Brewer RE; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Mascharak S; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.; Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University School of Medicine, Stanford University, Stanford, CA, USA., Lu L; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.; Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University School of Medicine, Stanford University, Stanford, CA, USA., Ajanaku O; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.; Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University School of Medicine, Stanford University, Stanford, CA, USA., Conley SD; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA., Seita J; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Center for Integrative Medical Sciences and Advanced Data Science Project, RIKEN, Tokyo, Japan., Morri M; Chan Zuckerberg BioHub, San Francisco, CA, USA., Neff NF; Chan Zuckerberg BioHub, San Francisco, CA, USA., Sahoo D; Pediatrics, and Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA., Yang F; Department of Bioengineering, Stanford University, Stanford, CA, USA., Weissman IL; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Ludwig Center for Cancer Stem Cell Biology and Medicine at Stanford University, Stanford, CA, USA., Longaker MT; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA. longaker@stanford.edu.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA. longaker@stanford.edu.; Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University School of Medicine, Stanford University, Stanford, CA, USA. longaker@stanford.edu., Chan CKF; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA. chazchan@stanford.edu.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA. chazchan@stanford.edu.; Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University School of Medicine, Stanford University, Stanford, CA, USA. chazchan@stanford.edu.

المصدر: Nature [Nature] 2021 Sep; Vol. 597 (7875), pp. 256-262. Date of Electronic Publication: 2021 Aug 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Cellular Senescence* , Stem Cell Niche*, Aging/*pathology , Bone and Bones/*pathology , Inflammation/*pathology , Stem Cells/*pathology, Animals ; Bone Morphogenetic Protein 2/metabolism ; Bone Regeneration ; Cell Lineage ; Female ; Fracture Healing ; Hematopoiesis ; Macrophage Colony-Stimulating Factor/metabolism ; Male ; Mice ; Myeloid Cells/cytology ; Osteoclasts/cytology ; Rejuvenation

المؤلفون: Travaglini KJ; Department of Biochemistry, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.; Vera Moulton Wall Center for Pulmonary Vascular Disease, Stanford University School of Medicine, Stanford, CA, USA., Nabhan AN; Department of Biochemistry, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.; Vera Moulton Wall Center for Pulmonary Vascular Disease, Stanford University School of Medicine, Stanford, CA, USA.; Genentech, South San Francisco, CA, USA., Penland L; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Calico Life Sciences, South San Francisco, CA, USA., Sinha R; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Gillich A; Department of Biochemistry, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.; Vera Moulton Wall Center for Pulmonary Vascular Disease, Stanford University School of Medicine, Stanford, CA, USA., Sit RV; Chan Zuckerberg Biohub, San Francisco, CA, USA., Chang S; Department of Biochemistry, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.; Vera Moulton Wall Center for Pulmonary Vascular Disease, Stanford University School of Medicine, Stanford, CA, USA., Conley SD; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Mori Y; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science, Fukuoka, Japan., Seita J; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Medical Sciences Innovation Hub Program, RIKEN, Tokyo, Japan., Berry GJ; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Shrager JB; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA., Metzger RJ; Vera Moulton Wall Center for Pulmonary Vascular Disease, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Stanford, CA, USA., Kuo CS; Department of Pediatrics, Pulmonary Medicine, Stanford University School of Medicine, Stanford, CA, USA., Neff N; Chan Zuckerberg Biohub, San Francisco, CA, USA., Weissman IL; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA., Quake SR; Chan Zuckerberg Biohub, San Francisco, CA, USA. steve@czbiohub.org.; Department of Bioengineering, Stanford University, Stanford, CA, USA. steve@czbiohub.org., Krasnow MA; Department of Biochemistry, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA. krasnow@stanford.edu.; Vera Moulton Wall Center for Pulmonary Vascular Disease, Stanford University School of Medicine, Stanford, CA, USA. krasnow@stanford.edu.

المصدر: Nature [Nature] 2020 Nov; Vol. 587 (7835), pp. 619-625. Date of Electronic Publication: 2020 Nov 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Immunity* , Sequence Analysis, RNA* , Single-Cell Analysis*, Cells/*classification , Cells/*metabolism , Lung/*cytology , Transcriptome/*genetics, Aged ; Animals ; Atlases as Topic ; Biomarkers ; Cell Communication ; Cells/immunology ; Chemokines/metabolism ; Endothelial Cells/metabolism ; Epithelial Cells/metabolism ; Female ; Humans ; Lung/immunology ; Male ; Mice ; Middle Aged ; Receptors, Lymphocyte Homing/metabolism ; Signal Transduction ; Stromal Cells/metabolism

المؤلفون: Chan CKF; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA. Electronic address: chazchan@stanford.edu., Gulati GS; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Sinha R; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Tompkins JV; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Lopez M; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Carter AC; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA., Ransom RC; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Reinisch A; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Wearda T; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Murphy M; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Brewer RE; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Koepke LS; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Marecic O; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Manjunath A; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Seo EY; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Leavitt T; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Lu WJ; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Nguyen A; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Conley SD; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Salhotra A; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Ambrosi TH; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Borrelli MR; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Siebel T; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Chan K; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Schallmoser K; Department of Blood Group Serology and Transfusion Medicine, Medical University of Graz, 8036 Graz, Austria., Seita J; Medical Sciences Innovation Hub Program, RIKEN, Tokyo 103-0027, Japan., Sahoo D; Departments of Pediatrics and Computer Science and Engineering, University of California San Diego, San Diego, CA 92093, USA., Goodnough H; Department of Orthopedic Surgery, Stanford Medicine, Stanford, CA 94305, USA., Bishop J; Department of Orthopedic Surgery, Stanford Medicine, Stanford, CA 94305, USA., Gardner M; Department of Orthopedic Surgery, Stanford Medicine, Stanford, CA 94305, USA., Majeti R; Department of Medicine, Division of Hematology, Stanford Medicine, Stanford, CA 94305, USA., Wan DC; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA., Goodman S; Department of Orthopedic Surgery, Stanford Medicine, Stanford, CA 94305, USA., Weissman IL; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Chang HY; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA., Longaker MT; Department of Surgery, Stanford Medicine, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA. Electronic address: longaker@stanford.edu.

المصدر: Cell [Cell] 2018 Sep 20; Vol. 175 (1), pp. 43-56.e21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Bone Development/*physiology , Bone and Bones/*cytology , Hematopoietic Stem Cells/*cytology, Animals ; Bone and Bones/metabolism ; Cartilage/cytology ; Cell Differentiation ; Humans ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/physiology ; Mesenchymal Stem Cells/cytology ; Mice ; Mice, Inbred C57BL ; Signal Transduction ; Single-Cell Analysis/methods ; Stem Cells/cytology ; Stromal Cells/cytology ; Transcriptome/genetics