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1A Diffusion-like Process Accommodates New Crypts During Clonal Expansion in Human Colonic Epithelium
المؤلفون: Nefeli Skoufou-Papoutsaki, Maria Chukanova, Shalini Malhotra, Rogier ten Hoopen, Kate Marks, Cora Olpe, D Winton, Rachael Stanley, Roxanne Brunton-Sim, Richard B. Kemp, Cerys Tatton, Cecilia Lindskog, Edward Morrissey, Anna M. Nicholson, Doran Khamis
المساهمون: Nicholson, Anna [0000-0001-9128-7024], Winton, Douglas [0000-0001-6067-7927], Apollo - University of Cambridge Repository
المصدر: Gastroenterology
مصطلحات موضوعية: bp, base pair, 0301 basic medicine, Male, FUFI, crypt fusion or fission form, Somatic cell, Colorectal cancer, Gene mutation, medicine.disease_cause, Intestinal Crypt, Diffusion, Full Report: Basic and Translational—Alimentary Tract, PCR, polymerase chain reaction, 0302 clinical medicine, Intestinal Mucosa, Original Research, Aged, 80 and over, Histone Demethylases, PPC, partially populated crypt, Gastroenterology, Age Factors, Middle Aged, Colorectal Cancer Initiation, Cell biology, FFPE, formalin-fixed paraffin-embedded, medicine.anatomical_structure, Cell Transformation, Neoplastic, CRC, colorectal cancer, Neoplastic Stem Cells, 030211 gastroenterology & hepatology, Female, KRAS, Colorectal Neoplasms, Adult, χ, contribution of mutant FUFIs to fusions, Adolescent, Crypt, Crypt Fusion, Colonic Polyps, Gastroenterology and Hepatology, Biology, Models, Biological, digestive system, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Young Adult, medicine, Gastroenterologi, Humans, Crypt Fission, Neoplastic transformation, MAF, mutant allele frequency, WPC, wholly populated crypt, M/M, mutant/mutant, Aged, Cell Proliferation, Cancer och onkologi, Hepatology, M/W, mutant/wild-type, Cancer, Epithelial Cells, medicine.disease, Epithelium, digestive system diseases, CI, confidence interval, 030104 developmental biology, Cancer and Oncology, Mutation
وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/octet-stream
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615ec7034c99f4cb8d21762818703993
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-456180 -
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المؤلفون: Shalini Malhotra, Kate Marks, Edward Morrissey, Rachel Stanley, Cerys Tatton, Cora Olpe, Anna M. Nicholson, Nefeli Skoufou-Papoutsaki, Rogier ten Hoopen, Maria Chukanova, Doran Khamis, Richard B. Kemp, Douglas J. Winton, Roxanne Brunton-Sim, Cecilia Lindskog
مصطلحات موضوعية: Somatic cell, digestive, oral, and skin physiology, Crypt, Gene mutation, Biology, digestive system, digestive system diseases, Epithelium, Cell biology, Histone, medicine.anatomical_structure, biology.protein, medicine, Immunohistochemistry, Demethylase, Stem cell
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5446dd9c845aaf9b72c2a51a38467e27
https://doi.org/10.1101/2020.07.10.193748 -
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