-
1دورية أكاديمية
المؤلفون: Lara Marrone, Ina Poser, Ian Casci, Julia Japtok, Peter Reinhardt, Antje Janosch, Cordula Andree, Hyun O. Lee, Claudia Moebius, Ellen Koerner, Lydia Reinhardt, Maria Elena Cicardi, Karl Hackmann, Barbara Klink, Angelo Poletti, Simon Alberti, Marc Bickle, Andreas Hermann, Udai Bhan Pandey, Anthony A. Hyman, Jared L. Sterneckert
المصدر: Stem Cell Reports, Vol 10, Iss 2, Pp 375-389 (2018)
مصطلحات موضوعية: Medicine (General), R5-920, Biology (General), QH301-705.5
وصف الملف: electronic resource
-
2
المؤلفون: Deric M. Park, Evelin Schroeck, George P. Chrousos, Carlo Vittorio Cannistraci, Steven W. Poser, Polyxeni Nikolakopoulou, Alan McIntyre, Petra Lennig, Oliver Otto, Andreas Androutsellis-Theotokis, Carina Arps-Forker, Barbara Klink, Jochen Guck, Mathias Lesche, Andreas Dahl, Yan Ge, Ronen R. Leker, Konrad Gruetzmann, Maik Herbig, Stefan R. Bornstein, Marc Bickle, Melissa F. Adasme, Michael Schroeder, Cordula Andree, Szymon Stodolak
المساهمون: University of Zurich, Androutsellis-Theotokis, Andreas
المصدر: The FASEB Journal. 33:9235-9249
مصطلحات موضوعية: 0301 basic medicine, 1303 Biochemistry, 10265 Clinic for Endocrinology and Diabetology, 610 Medicine & health, Biology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, 1311 Genetics, Cell Line, Tumor, Drug Discovery, 1312 Molecular Biology, Genetics, Humans, Molecular Biology, Transcription factor, Regulation of gene expression, Tumor microenvironment, Gene knockdown, Drug discovery, Gene Expression Profiling, Cell biology, Repressor Proteins, 030104 developmental biology, Gene Expression Regulation, Cell culture, Cancer cell, 1305 Biotechnology, RNA Interference, Signal transduction, Glioblastoma, 030217 neurology & neurosurgery, Signal Transduction, Biotechnology
-
3
المؤلفون: Ian Casci, Angelo Poletti, Julia Japtok, Claudia Moebius, Karl Hackmann, Marc Bickle, Udai Bhan Pandey, Barbara Klink, Ellen Koerner, Lydia Reinhardt, Antje Janosch, Anthony A. Hyman, Andreas Hermann, Simon Alberti, Lara Marrone, Cordula Andree, Jared Sterneckert, Peter Reinhardt, Ina Poser, Hyun O. Lee, Maria Elena Cicardi
المصدر: Stem Cell Reports
Stem Cell Reports, Vol 10, Iss 2, Pp 375-389 (2018)
Stem cell reports 10(2), 375-389 (2018). doi:10.1016/j.stemcr.2017.12.018مصطلحات موضوعية: 0301 basic medicine, amyotrophic lateral sclerosis, Drug Evaluation, Preclinical, FUS protein, Drosophila, Biochemistry, Green fluorescent protein, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, genetics [Drosophila Proteins], Drosophila Proteins, Amyotrophic lateral sclerosis, Induced pluripotent stem cell, lcsh:QH301-705.5, Motor Neurons, lcsh:R5-920, pharmacology [Antipyretics], gene editing, TOR Serine-Threonine Kinases, genetics [TOR Serine-Threonine Kinases], Phenotype, Antidepressive Agents, 3. Good health, Cell biology, metabolism [Induced Pluripotent Stem Cells], genetics [Amyotrophic Lateral Sclerosis], pharmacology [Antidepressive Agents], Drosophila, lcsh:Medicine (General), CRISPR/Cas9n, Signal Transduction, drug effects [Signal Transduction], MTOR protein, human, stress granules, autophagy, Antipyretics, genetics [Autophagy], pathology [Motor Neurons], induced pluripotent stem cells, genetics [Heterogeneous-Nuclear Ribonucleoprotein Group F-H], Green Fluorescent Proteins, Biology, Article, 03 medical and health sciences, Stress granule, Genetics, medicine, genetics [Green Fluorescent Proteins], Animals, Humans, ddc:610, pathology [Amyotrophic Lateral Sclerosis], Protein kinase B, PI3K/AKT/mTOR pathway, FUS, Heterogeneous-Nuclear Ribonucleoprotein Group F-H, metabolism [Amyotrophic Lateral Sclerosis], Autophagy, metabolism [Motor Neurons], Cell Biology, FUS protein, human, medicine.disease, 030104 developmental biology, lcsh:Biology (General), Mutation, RNA-Binding Protein FUS, genetics [Proto-Oncogene Proteins c-akt], CRISPR-Cas Systems, genetics [Phosphatidylinositol 3-Kinases], genetics [RNA-Binding Protein FUS], Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery, Developmental Biology
-
4
المؤلفون: Marc Bickle, Anthony Gavalas, Cordula Andree, Daniela Pezzolla, Vivian Anastasiou, Mathias Lesche, Ioannis Serafimidis, Ioannis Giannios
المصدر: Stem Cells 37, 640-651 (2019)
Stem Cells (Dayton, Ohio)مصطلحات موضوعية: Pluripotent Stem Cells, 0301 basic medicine, Methyltransferase, Cell, Aldehyde dehydrogenase, Nerve Tissue Proteins, Biology, Regenerative Medicine, Benzoates, Aldehyde Dehydrogenase 1 Family, Mice, 03 medical and health sciences, Aldehyde Dehydrogenase 1b1, Beta-cells, Embryonic Stem Cell Pancreas Differentiation, Pancreas Development, Endocrine Specification, Pancreatic Progenitors, 0302 clinical medicine, Downregulation and upregulation, Insulin-Secreting Cells, Basic Helix-Loop-Helix Transcription Factors, Diabetes Mellitus, medicine, Pancreas development, Animals, Humans, Aldehyde dehydrogenase 1b1, Protein Methyltransferases, Progenitor cell, Pancreas, Aldehyde Dehydrogenase, Mitochondrial, Pancreatic progenitors, Gene Expression Regulation, Developmental, Cell Differentiation, Mouse Embryonic Stem Cells, Cell Biology, Embryonic stem cell pancreas differentiation, Embryonic stem cell, Cell biology, β‐Cells, 030104 developmental biology, medicine.anatomical_structure, Xanthenes, biology.protein, Molecular Medicine, Endocrine specification, Stem cell, 030217 neurology & neurosurgery, Developmental Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a7dd9bda0a83f5329f078fb0d60aec
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=55529 -
5
المؤلفون: Kevin Fitzgerald, Pablo Amaya, Victor Koteliansky, Prasath Paramasivam, Marc Bickle, Jerome Gilleron, Martin Stöter, Giovanni Marsico, Sarah Seifert, Yannis Kalaidzidis, William Querbes, Marino Zerial, Herbert Waldmann, Akin Akinc, Muthiah Manoharan, Anja Zeigerer, Cordula Andree, Martin Maier
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Small interfering RNA, Endosome, Endocytic cycle, Endosomes, Biology, Endocytosis, Chemical library, Small Molecule Libraries, Mice, chemistry.chemical_compound, RNA interference, Genetics, Animals, Humans, Gene silencing, RNA, Small Interfering, Enhancer, Molecular Biology, Cells, Cultured, Endothelial Cells, Fibroblasts, Lipids, Cell biology, Cholesterol, chemistry, Hepatocytes, Nanoparticles, RNA Interference, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90bf0fe75ef47ddce247c890deae33e9
https://doi.org/10.1093/nar/gkv762 -
6
المؤلفون: Britta Schroth-Diez, Mihail Sarov, Thomas Kurth, Michele Solimena, Andreas Müller, Stephan Speier, B. P. Mulligan, Konstantinos Anastassiadis, Yannis Kalaidzidis, Carla Münster, Yanmei Liu, Michael Gerlach, Ronald Dirkx, Anna Ivanova, Cordula Andree, Marc Bickle
المصدر: Diabetes
مصطلحات موضوعية: medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Technological Advances, Motility, 030209 endocrinology & metabolism, Age dependent, Type 2 diabetes, Biology, Exocytosis, Cell Line, Islets of Langerhans, Mice, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Insulin Secretion, Internal Medicine, medicine, Animals, Humans, Insulin, Insulinoma, Cellular Senescence, Original Research, 030304 developmental biology, 0303 health sciences, Secretory Vesicles, Granule (cell biology), medicine.disease, Cell biology, SNAP-tag, Endocrinology, Proinsulin
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a5549ed117082f63c80de89be6dc06
https://doi.org/10.2337/db12-1819 -
7
المؤلفون: Chuanzheng Zhou, Dalibor Odadzic, Malgorzata Wenska, Torben Højland, Jens Haas, Jesper Wengel, Claus Bus, Maria Bach Laursen, Joachim W. Engels, Cordula Andree, Thomas F. Meyer, Puneet Srivastava, Simone Hess, Marino Zerial, Piet Herdewijn, Eugenio Fava, Jyoti Chattopadhyaya, Niels Langkjær, Elke Müller, Anne Færch Nielsen, Thomas B. Hansen, Mikhail Abramov, Romualdas Smicius, Dmytro Honcharenko, Georgii V. Bobkov, B. Ravindra Babu, Jesper B. Bramsen, Sergey N. Mikhailov, Jørgen Kjems, Arthur Van Aerschot, Jharna Barman
المصدر: Nucleic Acids Research
Bramsen, J B, Laursen, M B, Nielsen, A F, Hansen, T B, Bus, C, Langkjær, N, Babu, B R, Hojland, T, Abramov, M, Van Aerschot, A, Odadzic, D, Smicius, R, Haas, J, Andree, C, Barman, J, Wenska, M, Srivastava, P, Zhou, C, Honcharenko, D, Hess, S, Hess, S, Bobkov, G V, Mikhailov, S N, Fava, E, Meyer, T F, Chattopadhyaya, J, Zerial, M, Engels, J W, Herdewijn, P, Wengel, J & Kjems, J 2009, ' A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity ', Nucleic Acids Research, vol. 37, no. 9, pp. 2867-2881 . https://doi.org/10.1093/nar/gkp106
Bramsen, J B, Laursen, M B, Nielsen, A F, Hansen, T B, Bus, C, Langkjær, N, Babu, B R, Højland, T, Abramov, M, Van Aerschot, A, Odadzic, D, Smicius, R, Haas, J, Andree, C, Barman, J, Wenska, M, Srivastava, P, Zhou, C, Honcharenko, D, Hess, S, Müller, E, Bobkov, G V, Mikhailov, S N, Fava, E, Meyer, T F, Chattopadhyaya, J, Zerial, M, Engels, J W, Herdewijn, P, Wengel, J & Kjems, J 2009, ' A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity ', Nucleic Acids Research, vol. 37, no. 9, pp. 2867-81 . https://doi.org/10.1093/nar/gkp106مصطلحات موضوعية: Genetics, Small interfering RNA, RNA Stability, Cell Survival, RNA-induced silencing complex, RNA, Chemical modification, Computational biology, Biology, RNA interference, ddc:570, Cell Line, Tumor, Humans, RNA-Induced Silencing Complex, Gene silencing, RNA Interference, RNA, Small Interfering, Locked nucleic acid
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d12ff51f23c57bc31c94686cee7eb8
https://doi.org/10.1093/nar/gkp106 -
8
المؤلفون: Marc Bickle, Arshad Desai, Karen Oegema, Barbara Conradt, Esther Zanin, Cordula Andree, Alisa Piekny, Claudia Moebius, Yusuke Toyoda, Ina Poser
المصدر: Developmental Cell. (5):496-510
مصطلحات موضوعية: RHOA, Embryo, Nonmammalian, GTPase-activating protein, Cell division, Cell, Mitosis, Aster (cell biology), Microtubules, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Microtubule, medicine, Animals, Caenorhabditis elegans, Molecular Biology, 030304 developmental biology, Cytokinesis, 0303 health sciences, biology, 030302 biochemistry & molecular biology, GTPase-Activating Proteins, Gene Expression Regulation, Developmental, Cell Biology, Cell biology, medicine.anatomical_structure, biology.protein, rhoA GTP-Binding Protein, Cell Division, Developmental Biology, Muscle Contraction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f30cd3a9eb9313d2a429efae5b38497