المؤلفون: Elizabeth Stewart, Ross Goshorn, Cori Bradley, Lyra M. Griffiths, Claudia Benavente, Nathaniel R. Twarog, Gregory M. Miller, William Caufield, Burgess B. Freeman III, Armita Bahrami, Alberto Pappo, Jianrong Wu, Amos Loh, Åsa Karlström, Chris Calabrese, Brittney Gordon, Lyudmila Tsurkan, M. Jason Hatfield, Philip M. Potter, Scott E. Snyder, Suresh Thiagarajan, Abbas Shirinifard, Andras Sablauer, Anang A. Shelat, Michael A. Dyer

المصدر: Cell Reports, Vol 9, Iss 3, Pp 829-840 (2014)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124714008110; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/40a0e6c6da1444659221f51065bf900e

المؤلفون: Michael A. Dyer, Kip Guy, Fangyi Zhu, Clinton Stewart, Matthew Wilson, Jacqueline Flores-Otero, Jiakun Zhang, Cori Bradley, Sara Federico, Rachel C. Brennan

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bb6d014f0d763d55b44872272984cb
https://doi.org/10.1158/0008-5472.22387905

المؤلفون: Cori Bradley, Jason Dapper, Xin Zhou, Jianrong Wu, Armita Bahrami, James R. Downing, Sara M. Federico, Elizabeth Stewart, Asa Karlstrom, Alberto S. Pappo, Nathaniel R. Twarog, Kaley Blankenship, Anang A. Shelat, Jinghui Zhang, Burgess B. Freeman, Victoria Honnell, Richard K. Wilson, Monica Ocarz, John Easton, Beisi Xu, Brittney Gordon, Michael A. Dyer, Xiang Chen, Elaine R. Mardis, Michael R. Clay

المصدر: Nature

مصطلحات موضوعية: 0301 basic medicine, Vincristine, Indoles, Autopsy, Cell Cycle Proteins, Pyrimidinones, Hydroxamic Acids, Irinotecan, Article, Epigenesis, Genetic, Bortezomib, 03 medical and health sciences, chemistry.chemical_compound, Mice, In vivo, Panobinostat, Neoplasms, Rhabdomyosarcoma, medicine, Animals, Humans, Cancer epigenetics, Child, Multidisciplinary, business.industry, Cancer, Nuclear Proteins, Protein-Tyrosine Kinases, medicine.disease, Xenograft Model Antitumor Assays, 3. Good health, Clone Cells, High-Throughput Screening Assays, 030104 developmental biology, Pyrimidines, chemistry, Immunology, Cancer research, Heterografts, Pyrazoles, Camptothecin, Drug Therapy, Combination, Female, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2082ebbf9f6392081c9eedc9807c936f
http://europepmc.org/articles/PMC5659286

المؤلفون: Elizabeth Stewart, Sara M. Federico, Xiang Chen, Anang A. Shelat, Cori Bradley, Brittney Gordon, Asa Karlstrom, Nathaniel R. Twarog, Michael R. Clay, Armita Bahrami, Burgess B. Freeman, Bei

المصدر: Nature, Nature. 549(7670):96-100

الإتاحة: https://ideas.repec.org/a/nat/nature/v549y2017i7670d10.1038_nature23647.html

المؤلفون: Armita Bahrami, Alberto S. Pappo, Suresh Thiagarajan, Sara M. Federico, Abbas Shirinifard, Elizabeth Stewart, Anang A. Shelat, Cori Bradley, Xiang Chen, David Finkelstein, Michael A. Dyer, Andras Sablauer, Chunxu Qu

المصدر: Developmental biology

مصطلحات موضوعية: Adult, Lineage (genetic), Nonsense mutation, Biology, Article, Metastasis, 03 medical and health sciences, Mice, Neuroblastoma, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Cell Line, Tumor, medicine, Missense mutation, Animals, Humans, Epigenetics, Molecular Biology, 030304 developmental biology, 0303 health sciences, TOR Serine-Threonine Kinases, Cell Biology, medicine.disease, Primary tumor, Pediatric cancer, Immunohistochemistry, Xenograft Model Antitumor Assays, 3. Good health, High-Throughput Screening Assays, 030220 oncology & carcinogenesis, Immunology, Cancer research, Proto-Oncogene Proteins c-akt, Signal Transduction, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa71b852cd660eee26d1df85a6389d0a

المؤلفون: Vinay M. Daryani, Amy J. Funk, Cori Bradley, Christopher Calabrese, Amos Hong Pheng Loh, David Ross Goshorn, Armita Bahrami, Clinton F. Stewart, Michael A. Dyer, Xiang Chen, Peter Vogel, Elizabeth Stewart, Asa Karlstrom, Fred Krafcik, Greg Miller, Anang A. Shelat

المصدر: Cancer letters. 442

مصطلحات موضوعية: 0301 basic medicine, Drug, MAPK/ERK pathway, Cancer Research, media_common.quotation_subject, Bone Neoplasms, Mice, Transgenic, Mice, SCID, Poly(ADP-ribose) Polymerase Inhibitors, Article, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Doxorubicin, Molecular Targeted Therapy, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, media_common, Cell Proliferation, Osteosarcoma, Dose-Response Relationship, Drug, business.industry, Drug Repositioning, medicine.disease, Xenograft Model Antitumor Assays, Gemcitabine, High-Throughput Screening Assays, Tumor Burden, Histone Deacetylase Inhibitors, 030104 developmental biology, Oncology, Cell culture, 030220 oncology & carcinogenesis, Cancer research, Histone deacetylase, business, Proteasome Inhibitors, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9be97c7ff2053addaeaf250f430f58
https://pubmed.ncbi.nlm.nih.gov/30395907

المؤلفون: Monika Wierdl, Cori Bradley, Chunxu Qu, Philip M. Potter, M. Jason Hatfield, Xiang Chen, Viktor Tollemar, Lyudmila Tsurkan, Liying Chi

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Vincristine, Mice, Nude, Cell Growth Processes, Toxicology, Transfection, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Crizotinib, In vivo, hemic and lymphatic diseases, Cell Line, Tumor, Proto-Oncogene Proteins, Antineoplastic Combined Chemotherapy Protocols, Rhabdomyosarcoma, Medicine, Anaplastic lymphoma kinase, Animals, Humans, Pharmacology (medical), Anaplastic Lymphoma Kinase, Drug Interactions, Molecular Targeted Therapy, RNA, Small Interfering, Anaplastic large-cell lymphoma, Cyclophosphamide, Protein Kinase Inhibitors, Pharmacology, business.industry, Kinase, Cell growth, Protein-Tyrosine Kinases, Proto-Oncogene Proteins c-met, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Pyrimidines, Oncology, 030220 oncology & carcinogenesis, Cancer research, Dactinomycin, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d5cdce45e239548270d953b666f143
https://europepmc.org/articles/PMC6054567/

المؤلفون: Jiakun Zhang, Elizabeth Stewart, Praveen Kumar Suryadevara, Michael A. Dyer, Cori Bradley, Lei Yang, Fangyi Zhu, Lyra Griffiths, R. Kiplin Guy, Eleanor M. Pritchard, Burgess B. Freeman

المصدر: Pharmaceutical Research

مصطلحات موضوعية: Programmed cell death, Retinal Neoplasm, Pyridines, Retinal Neoplasms, medicine.medical_treatment, Pharmaceutical Science, Syk, Antineoplastic Agents, R406, Pharmacology, Biology, Eye, Targeted therapy, Mice, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Oxazines, medicine, Animals, Humans, Syk Kinase, Pharmacology (medical), Protein Kinase Inhibitors, Epigenomics, Ocular drug delivery, Cell Death, Retinoblastoma, Organic Chemistry, Intracellular Signaling Peptides and Proteins, Spleen tyrosine kinase, Protein-Tyrosine Kinases, medicine.disease, eye diseases, 3. Good health, Mice, Inbred C57BL, Clinical trial, Disease Models, Animal, 030220 oncology & carcinogenesis, 030221 ophthalmology & optometry, Cancer research, Molecular Medicine, Female, Research Paper, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dd8ac429a54a0d7c85849320a7c2eb
https://doi.org/10.1007/s11095-014-1399-y

المؤلفون: James R. Downing, Jianmin Wang, Walter H. Lang, Fred Krafcik, Michael Rusch, Kristy Boggs, Matthew Parker, Michael N. Edmonson, Nilsa C. Ramirez, Lei Wei, Steve Skapek, Li Ding, Anang A. Shelat, Justina McEvoy, Sara M. Federico, Elaine R. Mardis, Sheila A. Shurtleff, Jinghui Zhang, Heather L. Mulder, John A. Sandoval, Lyudmila Tsurkan, Andrew M. Davidoff, Viktor Tolleman, Charles Lu, Gang Wu, Chunxu Qu, Sheri L. Spunt, Cori Bradley, Panduka Nagahawatte, Elizabeth Stewart, Douglas S. Hawkins, Marcus B. Valentine, Richard K. Wilson, Philip M. Potter, Donald Yergeau, Xiang Chen, David Finkelstein, Monika Wierdl, Erin Hedlund, John Easton, Armita Bahrami, Virginia Valentine, Mark E. Hatley, Alberto S. Pappo, Christopher L. Morton, Michael A. Dyer

المصدر: Cancer Cell. 24:710-724

مصطلحات موضوعية: musculoskeletal diseases, Cancer Research, Gene Dosage, Loss of Heterozygosity, Biology, urologic and male genital diseases, medicine.disease_cause, Somatic evolution in cancer, Article, Clonal Evolution, Loss of heterozygosity, Mice, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, medicine, Animals, Homeostasis, Humans, Rhabdomyosarcoma, Embryonal, Copy-number variation, Rhabdomyosarcoma, neoplasms, 030304 developmental biology, 0303 health sciences, Mutation, Cancer, Cell Biology, medicine.disease, female genital diseases and pregnancy complications, 3. Good health, Oxidative Stress, Oncology, 030220 oncology & carcinogenesis, Immunology, Cancer research, Embryonal rhabdomyosarcoma, Sarcoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cfc5fd6dbca5911f62fc80acf1baf8
https://doi.org/10.1016/j.ccr.2013.11.002

المؤلفون: Sara M. Federico, Michael A. Dyer, Jacqueline Flores-Otero, Fangyi Zhu, Rachel C. Brennan, Matthew W. Wilson, Clinton F. Stewart, Jiakun Zhang, Kip Guy, Cori Bradley

المصدر: Cancer Research. 71:4205-4213

مصطلحات موضوعية: Cancer Research, Programmed cell death, Retinal Neoplasm, MDMX, Retinal Neoplasms, medicine.medical_treatment, Mice, SCID, Piperazines, Article, Mice, medicine, Animals, Humans, Intraocular Pressure, Chemotherapy, biology, Retinoblastoma, Imidazoles, Proto-Oncogene Proteins c-mdm2, medicine.disease, Xenograft Model Antitumor Assays, eye diseases, Mice, Inbred C57BL, Clinical trial, Disease Models, Animal, Solubility, Oncology, Immunology, Cancer research, biology.protein, Mdm2, Topotecan, Tumor Suppressor Protein p53, Conjunctiva, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0cddb66fdb81901260557b61560ce4
https://doi.org/10.1158/0008-5472.can-11-0058