المؤلفون: Esther Melo, Philipp Oertle, Carolyn Trepp, Hélène Meistermann, Thomas Burgoyne, Lorenzo Sborgi, Alvaro Cortes Cabrera, Chia-yi Chen, Jean-Christophe Hoflack, Tony Kam-Thong, Roland Schmucki, Laura Badi, Nicholas Flint, Zeynep Eren Ghiani, Fréderic Delobel, Corinne Stucki, Giulia Gromo, Alfred Einhaus, Benoit Hornsperger, Sabrina Golling, Juliane Siebourg-Polster, Francoise Gerber, Bernd Bohrmann, Clare Futter, Tom Dunkley, Sebastian Hiller, Oliver Schilling, Volker Enzmann, Sascha Fauser, Marija Plodinec, Roberto Iacone

المصدر: EBioMedicine, Vol 27, Iss C, Pp 258-274 (2018)

مصطلحات موضوعية: Age-related macular degeneration, Polarized human retinal, pigmented epithelium, HtrA serine peptidase 1, Disease modelling, Mechanical properties, Cell stiffness, Phagocytic activity, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396417304929; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/98697e83512f42e8992a6dee356485cc

المؤلفون: Anne Enzbrenner, Rahel Zulliger, Josef Biber, Ana Maria Quintela Pousa, Nicole Schäfer, Corinne Stucki, Nicolas Giroud, Marco Berrera, Elod Kortvely, Roland Schmucki, Laura Badi, Antje Grosche, Diana Pauly, Volker Enzmann

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 17, p 9218 (2021)

مصطلحات موضوعية: retinal degeneration, geographic atrophy, sodium iodate, local complement, inflammation, innate immunity, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/22/17/9218; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/638cb1d6b0214fe59ccbc858d16d2266

المؤلفون: Corinne Stucki, Carel B. Hoyng, Laura Lorés-Motta, Bjorn Bakker, Anneke I. den Hollander, Taco W. Kuijpers, Ilse Jongerius, Esther Willems, Simon J. Clark, Elod Koertvely, Alfred Einhaus, Gerard van Mierlo, Everson Nogoceke, Sascha Fauser, Judith Zandstra, Jean-Luc Mary, Marien I. de Jonge, Anna E. van Beek

المساهمون: Graduate School, Landsteiner Laboratory, Paediatric Infectious Diseases / Rheumatology / Immunology, ARD - Amsterdam Reproduction and Development

المصدر: American Journal of Human Genetics
The American Journal of Human Genetics
American Journal of Human Genetics, 108, 8, pp. 1367-1384
American Journal of Human Genetics, 108, 1367-1384
Lorés-Motta, L, van Beek, A, Willems, E, Zandstra, J, van Mierlo, G, Einhaus, A, Mary, J-L, Stucki, C, Bakker, B, Hoyng, C, Fauser, S, Clark, S, de Jonge, M, Nogoceke, E, Koertvely, E, Jongerius, I, Kuijpers, T & den Hollander, A 2021, ' Common haplotypes at the CFH locus and low-frequency variants in CFHR2 and CFHR5 associate with systemic FHR levels and age-related macular degeneration ', Am J Hum Genet . https://doi.org/10.1016/j.ajhg.2021.06.002
American journal of human genetics, 108(8), 1367-1384. Cell Press

مصطلحات موضوعية: CFHR5, genetic structures, CFHR2, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Locus (genetics), Genome-wide association study, Biology, Drusen, AMD, complement-factor-H-related, Polymorphism, Single Nucleotide, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], Article, Cohort Studies, 03 medical and health sciences, Macular Degeneration, All institutes and research themes of the Radboud University Medical Center, 0302 clinical medicine, Genotype, Genetics, medicine, Complement C3b Inactivator Proteins, Humans, Genetic Predisposition to Disease, age-related macular degeneration, Genetics (clinical), complement system, 030304 developmental biology, 0303 health sciences, complement Factor H, Haplotype, Complement System Proteins, Macular degeneration, medicine.disease, eye diseases, 3. Good health, Haplotypes, Factor H, embryonic structures, 030221 ophthalmology & optometry, CFH, sense organs, Genome-Wide Association Study

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3a920e528b8e45e1981b13be551973
https://pubmed.ncbi.nlm.nih.gov/34260947

المؤلفون: Juliane Siebourg-Polster, Volker Enzmann, Laura Badi, Jean-Christophe Hoflack, Tony Kam-Thong, Esther Melo, Giulia Gromo, Zeynep Eren Ghiani, Alvaro Cortes Cabrera, Roberto Iacone, Sascha Fauser, Benoit Hornsperger, Sebastian Hiller, Thomas Burgoyne, Francoise Gerber, Lorenzo Sborgi, Sabrina Golling, Nicholas Flint, Chia-yi Chen, Marija Plodinec, Roland Schmucki, Hélène Meistermann, Alfred Einhaus, Oliver Schilling, Philipp Oertle, Clare E. Futter, Frederic Delobel, Carolyn Trepp, Tom Dunkley, Corinne Stucki, Bernd Bohrmann

المصدر: EBioMedicine
EBioMedicine, Vol 27, Iss C, Pp 258-274 (2018)
Melo, Esther; Oertle, Philipp; Trepp, Carolyn Mary; Meistermann, Hélène; Burgoyne, Thomas; Sborgi, Lorenzo; Cabrera, Alvaro Cortes; Chen, Chia-Yi; Hoflack, Jean-Christophe; Kam-Thong, Tony; Schmucki, Roland; Badi, Laura; Flint, Nicholas; Ghiani, Zeynep Eren; Delobel, Fréderic; Stucki, Corinne; Gromo, Giulia; Einhaus, Alfred; Hornsperger, Benoit; Golling, Sabrina; ... (2018). HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model. EBioMedicine, 27, pp. 258-274. Elsevier 10.1016/j.ebiom.2017.12.011 <http://dx.doi.org/10.1016/j.ebiom.2017.12.011>

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, genetic structures, lcsh:Medicine, Mechanical properties, Retinal Pigment Epithelium, Phagocytic activity, Microtubules, Polymerization, chemistry.chemical_compound, Macular Degeneration, 0302 clinical medicine, Cell stiffness, Tubulin, 610 Medicine & health, lcsh:R5-920, biology, Chemistry, Cell Polarity, General Medicine, Adherens Junctions, High-Temperature Requirement A Serine Peptidase 1, Phenotype, Cell biology, Disease modelling, lcsh:Medicine (General), Intracellular, Research Paper, Protein Binding, Adult, Drusen, Models, Biological, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Protein Aggregates, Fetus, Phagocytosis, Microtubule, medicine, Humans, Age-related macular degeneration, lcsh:R, Retinal, HtrA serine peptidase 1, Macular degeneration, medicine.disease, Polarized human retinal, pigmented epithelium, eye diseases, 030104 developmental biology, HTRA1, Mutation, 030221 ophthalmology & optometry, biology.protein, Nanoparticles, sense organs

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e980298c37719f2e698c7daab9b7e6b

المؤلفون: Roberto Iacone, Frederic Delobel, Verena Kueppers, Sascha Fauser, Peter Jakob, Esther Melo, Peter Goettig, Chia-yi Chen, Tom Dunkley, Brigitta Elsässer, Oliver Schilling, Arno Friedlein, Corinne Stucki

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Proteome, Angiogenesis, Primary Cell Culture, Cleavage (embryo), Extracellular matrix, Thrombospondin 1, 03 medical and health sciences, Macular Degeneration, 0302 clinical medicine, Downregulation and upregulation, medicine, Electric Impedance, Human Umbilical Vein Endothelial Cells, Humans, Amino Acid Sequence, Serine protease HtrA1, Molecular Biology, Age-related degeneration, Aged, Retina, Chemistry, Gene Expression Profiling, Epithelial Cells, High-Temperature Requirement A Serine Peptidase 1, Polarized secretome analysis, Peptide Fragments, eye diseases, Cell biology, Extracellular Matrix, Gene expression profiling, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, Cell culture, 030220 oncology & carcinogenesis, Culture Media, Conditioned, Proteolysis, Diffusion Chambers, Culture, Angiogenesis Inducing Agents, Retinal Pigments

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcd7a1ff777817f7be54cc9b2443217
https://eplus.uni-salzburg.at/doi/10.1016/j.matbio.2018.03.013

المؤلفون: Paula M. Petrone, Roberto Iacone, Esther Melo, Peter Jakob, Corinne Stucki, Chia-yi Chen, Oliver Schilling, Frederic Delobel, Doris Roth, Alvaro Cortes Cabrera, Balazs Banfai, Andreas Topp, Sylwia Huber, Tom Dunkley

المصدر: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

مصطلحات موضوعية: 0301 basic medicine, Amyloid beta, medicine.medical_treatment, Protein domain, Allosteric regulation, lcsh:Medicine, Trimer, tau Proteins, Fibril, Article, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Allosteric Regulation, Protein Domains, Tubulin, medicine, Humans, lcsh:Science, Multidisciplinary, Protease, Amyloid beta-Peptides, biology, Chemistry, lcsh:R, High-Temperature Requirement A Serine Peptidase 1, eye diseases, Cell biology, 030104 developmental biology, HTRA1, Proteolysis, biology.protein, lcsh:Q, Protein folding, Protein Multimerization, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6615ef46353d20a6a7546d2650449b29
http://europepmc.org/articles/PMC5666011

المؤلفون: Jean-Claude Tardif, Sven Kronenberg, Jacques Gaudreault, Dietrich Tuerck, Dorothee Kling, Christophe Schmitt, Corinne Stucki, Eric Rhéaume

المصدر: Thrombosis Research. 131:401-410

مصطلحات موضوعية: Adult, Blood Platelets, Male, Adolescent, Cell Communication, Pharmacology, Young Adult, Thrombin, Inclacumab, In vivo, Leukocytes, medicine, Animals, Humans, Platelet, Platelet activation, Aged, business.industry, Antibodies, Monoclonal, Hematology, Middle Aged, Platelet Activation, Macaca fascicularis, P-Selectin, Treatment Outcome, Immunology, Female, P-selectin glycoprotein ligand-1, business, Selectin, Ex vivo, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6279c0bf2f0fc01e8072063454945374
https://doi.org/10.1016/j.thromres.2013.02.020