المؤلفون: Khemka N; Centre for Systems Medicine & Dept. of Physiology & Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland., Morris G; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; Neuroscience, Physiology and Pharmacology, University College London, London, UK.; Division of Neuroscience, University of Manchester, Manchester, UK., Kazemzadeh L; Centre for Systems Medicine & Dept. of Physiology & Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland., Costard LS; Epilepsy Center, Department of Neurology, Philipps University Marburg, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe-University, Frankfurt, Germany., Neubert V; Epilepsy Center, Department of Neurology, Philipps University Marburg, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe-University, Frankfurt, Germany., Bauer S; Epilepsy Center, Department of Neurology, Philipps University Marburg, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe-University, Frankfurt, Germany., Rosenow F; Epilepsy Center, Department of Neurology, Philipps University Marburg, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe-University, Frankfurt, Germany., Venø MT; Interdisciplinary Nanoscience Center, Dept. of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.; Omiics ApS, Aarhus, Denmark., Kjems J; Interdisciplinary Nanoscience Center, Dept. of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Henshall DC; Centre for Systems Medicine & Dept. of Physiology & Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland., Prehn JHM; Centre for Systems Medicine & Dept. of Physiology & Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland. prehn@rcsi.com.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. prehn@rcsi.com., Connolly NMC; Centre for Systems Medicine & Dept. of Physiology & Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland. niamhmconnolly@rcsi.com.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. niamhmconnolly@rcsi.com.

المصدر: Scientific reports [Sci Rep] 2024 Jul 03; Vol. 14 (1), pp. 15313. Date of Electronic Publication: 2024 Jul 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: MicroRNAs*/genetics , MicroRNAs*/metabolism , RNA, Messenger*/genetics , RNA, Messenger*/metabolism , Gene Regulatory Networks* , Seizures*/genetics , Seizures*/metabolism , Epilepsy*/genetics , Epilepsy*/metabolism , Gene Expression Profiling*, Animals ; Rats ; Male ; Gene Expression Regulation ; Bayes Theorem ; Disease Models, Animal ; Transcriptome

المؤلفون: Heiland M; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland., Connolly NMC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland., Mamad O; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland., Nguyen NT; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland., Kesavan JC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland., Langa E; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland., Fanning K; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland., Sanfeliu A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland., Yan Y; Interdisciplinary Nanoscience Centre, Aarhus University, 8000 Aarhus C, Denmark.; Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark.; Omiics, 8200 Aarhus N, Denmark., Su J; Interdisciplinary Nanoscience Centre, Aarhus University, 8000 Aarhus C, Denmark.; Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark., Venø MT; Interdisciplinary Nanoscience Centre, Aarhus University, 8000 Aarhus C, Denmark.; Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark.; Omiics, 8200 Aarhus N, Denmark., Costard LS; Epilepsy Center, Department of Neurology, Philipps University Marburg, Marburg 35043, Germany.; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt, Frankfurt a.M. 60528, Germany.; Landes-Offensive zur Entwicklung Wissenschaftlich-ökonomischer Exzellenz, Center for Personalized Translational Epilepsy Research, Goethe-University Frankfurt, Frankfurt a.M. 60528, Germany., Neubert V; Epilepsy Center, Department of Neurology, Philipps University Marburg, Marburg 35043, Germany., Engel T; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland., Hill TDM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland., Freiman TM; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt, Frankfurt a.M. 60528, Germany.; Department of Neurosurgery, University of Rostock, Rostock 18057, Germany., Mahesh A; Institute of Molecular Medicine, University of Southern Denmark, 5000 Odense, Denmark., Tiwari VK; Institute of Molecular Medicine, University of Southern Denmark, 5000 Odense, Denmark.; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queens University, Belfast BT9 7BL, United Kingdom.; Danish Institute for Advanced Study, University of Southern Denmark, 5230 Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, 5000 Odense, Denmark., Rosenow F; Epilepsy Center, Department of Neurology, Philipps University Marburg, Marburg 35043, Germany.; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt, Frankfurt a.M. 60528, Germany.; Landes-Offensive zur Entwicklung Wissenschaftlich-ökonomischer Exzellenz, Center for Personalized Translational Epilepsy Research, Goethe-University Frankfurt, Frankfurt a.M. 60528, Germany., Bauer S; Epilepsy Center, Department of Neurology, Philipps University Marburg, Marburg 35043, Germany.; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt, Frankfurt a.M. 60528, Germany.; Landes-Offensive zur Entwicklung Wissenschaftlich-ökonomischer Exzellenz, Center for Personalized Translational Epilepsy Research, Goethe-University Frankfurt, Frankfurt a.M. 60528, Germany., Kjems J; Interdisciplinary Nanoscience Centre, Aarhus University, 8000 Aarhus C, Denmark.; Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark., Morris G; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, United Kingdom., Henshall DC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.; FutureNeuro Science Foundation Ireland Research Centre, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin D02 YN77, Ireland.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Jul 25; Vol. 120 (30), pp. e2216658120. Date of Electronic Publication: 2023 Jul 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Induced Pluripotent Stem Cells*/metabolism , Epilepsy* , MicroRNAs*/genetics , MicroRNAs*/metabolism , Voltage-Gated Sodium Channels*/genetics, Humans ; Mice ; Rats ; Animals ; Seizures/chemically induced ; Seizures/genetics ; Seizures/metabolism ; NAV1.1 Voltage-Gated Sodium Channel/genetics ; NAV1.1 Voltage-Gated Sodium Channel/metabolism ; NAV1.3 Voltage-Gated Sodium Channel/genetics

المؤلفون: Siebenbrodt K; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt and LOEWE Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt, 60528 Frankfurt am Main, Germany.; Department of Neurology, Philipps University, 35037 Marburg, Germany., Schütz V; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt and LOEWE Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt, 60528 Frankfurt am Main, Germany., Costard LS; Department of Neurology, Philipps University, 35037 Marburg, Germany.; Tissue Engineering Research Group, RCSI Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland, D02 YN77 Dublin, Ireland., Neubert V; Department of Neurology, Philipps University, 35037 Marburg, Germany.; Oscar-Langendorff-Institute of Physiology, Rostock University Medical Center, 18057 Rostock, Germany., Alvarez-Fischer D; Institute of Neurogenetics, University of Lübeck, 23538 Lübeck, Germany., Seidel K; Institute for Lung Research, Universities of Giessen and Marburg Lung Center, Philipps-University Marburg, 35037 Marburg, Germany., Schmeck B; Institute for Lung Research, Universities of Giessen and Marburg Lung Center, Philipps-University Marburg, 35037 Marburg, Germany.; German Centers for Lung Research (DZL) and for Infectious Disease Research (DZIF), SYNMIKRO Centre for Synthetic Microbiology, Philipps-University Marburg, 35037 Marburg, Germany., Meuth SG; Department of Neurology, Medical Faculty, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Rosenow F; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt and LOEWE Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt, 60528 Frankfurt am Main, Germany.; Department of Neurology, Philipps University, 35037 Marburg, Germany., Bauer S; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt and LOEWE Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt, 60528 Frankfurt am Main, Germany.; Department of Neurology, Philipps University, 35037 Marburg, Germany.

المصدر: Brain sciences [Brain Sci] 2022 May 21; Vol. 12 (5). Date of Electronic Publication: 2022 May 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101598646 Publication Model: Electronic Cited Medium: Print ISSN: 2076-3425 (Print) Linking ISSN: 20763425 NLM ISO Abbreviation: Brain Sci Subsets: PubMed not MEDLINE

المؤلفون: Costard LS; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland., Hosn RR; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland; Trinity Centre of Bioengineering (TCBE), Trinity College Dublin (TCD), Dublin, Ireland; Dept. of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin (TCD), the University of Dublin, Ireland., Ramanayake H; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland., O'Brien FJ; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland; Trinity Centre of Bioengineering (TCBE), Trinity College Dublin (TCD), Dublin, Ireland; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI and TCD, Dublin, Ireland., Curtin CM; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland; Trinity Centre of Bioengineering (TCBE), Trinity College Dublin (TCD), Dublin, Ireland; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI and TCD, Dublin, Ireland. Electronic address: carolinecurtin@rcsi.ie.

المصدر: Acta biomaterialia [Acta Biomater] 2021 Sep 15; Vol. 132, pp. 360-378. Date of Electronic Publication: 2021 Jan 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE

مواضيع طبية MeSH: Prostatic Neoplasms* , Tumor Microenvironment*, Animals ; Breast ; Cell Line, Tumor ; Humans ; Lung ; Male

المؤلفون: Costard LS; Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), 123 St Stephen's Green, D02 YN77 Dublin, Ireland., Kelly DC; Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), 123 St Stephen's Green, D02 YN77 Dublin, Ireland.; Centre for Research in Medical Devices (CÚRAM), Biomedical Sciences Building, National University of Ireland, Galway (NUI, Galway), H91 TK33 Galway, Ireland., Power RN; Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), 123 St Stephen's Green, D02 YN77 Dublin, Ireland., Hobbs C; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI and Trinity College Dublin (TCD), College Green, D02 PN40 Dublin, Ireland.; School of Chemistry and Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College Dublin, College Green, D02 PN40 Dublin, Ireland., Jaskaniec S; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI and Trinity College Dublin (TCD), College Green, D02 PN40 Dublin, Ireland.; School of Chemistry and Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College Dublin, College Green, D02 PN40 Dublin, Ireland., Nicolosi V; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI and Trinity College Dublin (TCD), College Green, D02 PN40 Dublin, Ireland.; School of Chemistry and Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College Dublin, College Green, D02 PN40 Dublin, Ireland., Cavanagh BL; Cellular and Molecular Imaging Core, RCSI, 123 St Stephen's Green, D02 YN77 Dublin, Ireland., Curtin CM; Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), 123 St Stephen's Green, D02 YN77 Dublin, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI and Trinity College Dublin (TCD), College Green, D02 PN40 Dublin, Ireland.; Trinity Centre for BioMedical Engineering, Trinity Biomedical Sciences Institute, TCD, College Green, D02 PN40 Dublin, Ireland., O'Brien FJ; Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), 123 St Stephen's Green, D02 YN77 Dublin, Ireland.; Centre for Research in Medical Devices (CÚRAM), Biomedical Sciences Building, National University of Ireland, Galway (NUI, Galway), H91 TK33 Galway, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI and Trinity College Dublin (TCD), College Green, D02 PN40 Dublin, Ireland.; Trinity Centre for BioMedical Engineering, Trinity Biomedical Sciences Institute, TCD, College Green, D02 PN40 Dublin, Ireland.

المصدر: Pharmaceutics [Pharmaceutics] 2020 Dec 16; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE

المؤلفون: Brennan GP; School of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Center, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland. Electronic address: gary.brennan@ucd.ie., Bauer S; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research (CePTER), Goethe University, Frankfurt, Germany; Department of Neurology, Phillips University, Marburg, Germany., Engel T; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Center, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Jimenez-Mateos EM; Discipline of Physiology, School of Medicine, Trinity College Dublin, Dublin, Ireland., Del Gallo F; Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy., Hill TDM; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Center, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Connolly NMC; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Costard LS; Department of Neurology, Phillips University, Marburg, Germany; Department of Regenerative Medicine, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Neubert V; Department of Neurology, Phillips University, Marburg, Germany; Oscar-Langendorff Institute of Physiology, Rostock University Medical Center, Germany., Salvetti B; Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy., Sanz-Rodriguez A; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Center, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Heiland M; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Center, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Mamad O; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Center, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Brindley E; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Norwood B; Expesicor Inc, Kalispell, MT, USA; FYR Diagnostics, Missoula, MT, USA., Batool A; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Raoof R; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., El-Naggar H; School of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland., Reschke CR; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Center, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Delanty N; FutureNeuro SFI Research Center, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland; Department of Neurology, Beaumont Hospital, Dublin, Ireland; Department of Molecular and Cellular Therapeutics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Prehn JHM; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Center, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland., Fabene P; Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy., Mooney C; FutureNeuro SFI Research Center, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland; School of Computer Science, University College Dublin, Ireland., Rosenow F; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research (CePTER), Goethe University, Frankfurt, Germany; Department of Neurology, Phillips University, Marburg, Germany., Henshall DC; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Center, Royal College of Surgeons Ireland, Dublin D02 YN77, Ireland.

المصدر: Neurobiology of disease [Neurobiol Dis] 2020 Oct; Vol. 144, pp. 105048. Date of Electronic Publication: 2020 Aug 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Circulating MicroRNA/*genetics , Epilepsy, Temporal Lobe/*genetics, Animals ; Anticonvulsants/pharmacology ; Blood-Brain Barrier/metabolism ; Circulating MicroRNA/drug effects ; Disease Models, Animal ; Electric Stimulation ; Epilepsy, Temporal Lobe/blood ; Epilepsy, Temporal Lobe/chemically induced ; Excitatory Amino Acid Agonists/toxicity ; Kainic Acid/toxicity ; Male ; Mice ; Muscarinic Agonists/toxicity ; Perforant Pathway ; Pilocarpine/toxicity ; Rats

المؤلفون: Venø MT; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Reschke CR; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Morris G; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Connolly NMC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Su J; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Yan Y; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Engel T; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Jimenez-Mateos EM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Harder LM; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark., Pultz D; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark., Haunsberger SJ; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Pal A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Heller JP; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Campbell A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Langa E; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Brennan GP; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Conboy K; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Richardson A; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Norwood BA; Department of Neuroscience, Expesicor Inc, Kalispell, MT 59901.; Diagnostics Development, FYR Diagnostics, Missoula, MT 59801., Costard LS; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany., Neubert V; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Oscar-Langendorff-Institute of Physiology, Rostock University Medical Center, Rostock, 18051, Germany., Del Gallo F; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy., Salvetti B; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy., Vangoor VR; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Sanz-Rodriguez A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Muilu J; Research and Development, BC Platforms, FI-02130, Espoo, Finland., Fabene PF; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy., Pasterkamp RJ; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Prehn JHM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Schorge S; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom.; UCL School of Pharmacy, University College London, London, WC1N 1AX, United Kingdom., Andersen JS; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark., Rosenow F; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany., Bauer S; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany., Kjems J; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Henshall DC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland; dhenshall@rcsi.ie.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 07; Vol. 117 (27), pp. 15977-15988. Date of Electronic Publication: 2020 Jun 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Epilepsy, Temporal Lobe/*drug therapy , Epilepsy, Temporal Lobe/*metabolism , MicroRNAs/*drug effects , MicroRNAs/*metabolism , Oligonucleotides, Antisense/*pharmacology , Seizures/*drug therapy , Seizures/*metabolism, Animals ; Antagomirs/pharmacology ; Argonaute Proteins/genetics ; Argonaute Proteins/metabolism ; Biomarkers ; Disease Models, Animal ; Epilepsy ; Female ; Hippocampus/metabolism ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; MicroRNAs/genetics ; Proteomics ; Rats ; Rats, Sprague-Dawley ; Seizures/genetics ; Systems Analysis ; Up-Regulation/drug effects

المؤلفون: Costard LS; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research (CePTER), Goethe University, Frankfurt, Germany; Department of Neurology, Philipps University, Marburg, Germany. Electronic address: laracostard@rcsi.com., Neubert V; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research (CePTER), Goethe University, Frankfurt, Germany; Department of Neurology, Philipps University, Marburg, Germany., Venø MT; Department of Molecular Biology and Genetics and Interdisciplinary Nanoscience Center, Aarhus University, Aarhus, Denmark., Su J; Department of Molecular Biology and Genetics and Interdisciplinary Nanoscience Center, Aarhus University, Aarhus, Denmark., Kjems J; Department of Molecular Biology and Genetics and Interdisciplinary Nanoscience Center, Aarhus University, Aarhus, Denmark., Connolly NMC; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Prehn JHM; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Schratt G; Lab of Systems Neuroscience, Institute for Neuroscience, Department of Health Science and Technology, ETH Zurich, Zurich, Switzerland., Henshall DC; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland; FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin, D02, Ireland., Rosenow F; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research (CePTER), Goethe University, Frankfurt, Germany; Department of Neurology, Philipps University, Marburg, Germany., Bauer S; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research (CePTER), Goethe University, Frankfurt, Germany; Department of Neurology, Philipps University, Marburg, Germany.

المصدر: Brain stimulation [Brain Stimul] 2019 Nov - Dec; Vol. 12 (6), pp. 1390-1401. Date of Electronic Publication: 2019 Jun 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101465726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-4754 (Electronic) Linking ISSN: 18764754 NLM ISO Abbreviation: Brain Stimul Subsets: MEDLINE

مواضيع طبية MeSH: Deep Brain Stimulation/*methods , Epilepsy, Temporal Lobe/*metabolism , Epilepsy, Temporal Lobe/*therapy , Fornix, Brain/*metabolism , MicroRNAs/*biosynthesis, Animals ; Epilepsy, Temporal Lobe/genetics ; Gene Expression ; Male ; MicroRNAs/genetics ; Rats ; Rats, Sprague-Dawley ; Seizures/genetics ; Seizures/metabolism ; Seizures/therapy