المؤلفون: Nguyen, MA, Hoang, HD, Rasheed, A, Duchez, AC, Wyatt, H, Cottee, ML, Graber, TE, Susser, L, Robichaud, S, Berber, I, Geoffrion, M, Ouimet, M, Kazan, H, Maegdefessel, L, Mulvihill, EE, Alain, T, Rayner, KJ

المصدر: Circulation research. 131(1):42-58

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:150014721

المؤلفون: Wedge ME; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada., Jennings VA; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Institute of Cancer Research, London, UK.; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Crupi MJF; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Poutou J; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Jamieson T; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Pelin A; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Pugliese G; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., de Souza CT; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Petryk J; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Laight BJ; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Boileau M; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Taha Z; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Alluqmani N; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., McKay HE; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Pikor L; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Khan ST; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Azad T; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Rezaei R; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Austin B; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., He X; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Mansfield D; Institute of Cancer Research, London, UK., Rose E; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Brown EEF; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Crawford N; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Alkayyal A; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia., Surendran A; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Singaravelu R; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Roy DG; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Migneco G; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., McSweeney B; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Cottee ML; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Jacobus EJ; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Oncology, University of Oxford, Oxford, UK., Keller BA; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Yamaguchi TN; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA., Boutros PC; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Urology, University of California, Los Angeles, Los Angeles, CA, USA.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Geoffrion M; University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Rayner KJ; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.; University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Chatterjee A; The Ottawa Hospital, Division of Gastroenterology, Ottawa, Ontario, Canada., Auer RC; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.; Department of Surgery, University of Ottawa, Ottawa, Ontario, Canada., Diallo JS; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Gibbings D; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada., tenOever BR; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Melcher A; Institute of Cancer Research, London, UK., Bell JC; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Ilkow CS; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. cilkow@uottawa.ca.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada. cilkow@uottawa.ca.

المصدر: Nature communications [Nat Commun] 2022 Apr 07; Vol. 13 (1), pp. 1898. Date of Electronic Publication: 2022 Apr 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Extracellular Vesicles* , MicroRNAs*/genetics , Neoplasms*/therapy , Oncolytic Virotherapy* , Oncolytic Viruses*/genetics, Humans

المؤلفون: Rasheed A; From the University of Ottawa Heart Institute, ON, Canada (A.R., S.R., M.-A.N., M.G., H.W., M.L.C., T.D., A.P., T.A.L., M.O., K.J.R.)., Robichaud S; From the University of Ottawa Heart Institute, ON, Canada (A.R., S.R., M.-A.N., M.G., H.W., M.L.C., T.D., A.P., T.A.L., M.O., K.J.R.).; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, ON, Canada (S.R., M.-A.N., M.L.C., T.A.L., M.O., K.J.R.)., Nguyen MA; From the University of Ottawa Heart Institute, ON, Canada (A.R., S.R., M.-A.N., M.G., H.W., M.L.C., T.D., A.P., T.A.L., M.O., K.J.R.).; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, ON, Canada (S.R., M.-A.N., M.L.C., T.A.L., M.O., K.J.R.)., Geoffrion M; From the University of Ottawa Heart Institute, ON, Canada (A.R., S.R., M.-A.N., M.G., H.W., M.L.C., T.D., A.P., T.A.L., M.O., K.J.R.)., Wyatt H; From the University of Ottawa Heart Institute, ON, Canada (A.R., S.R., M.-A.N., M.G., H.W., M.L.C., T.D., A.P., T.A.L., M.O., K.J.R.)., Cottee ML; From the University of Ottawa Heart Institute, ON, Canada (A.R., S.R., M.-A.N., M.G., H.W., M.L.C., T.D., A.P., T.A.L., M.O., K.J.R.).; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, ON, Canada (S.R., M.-A.N., M.L.C., T.A.L., M.O., K.J.R.)., Dennison T; From the University of Ottawa Heart Institute, ON, Canada (A.R., S.R., M.-A.N., M.G., H.W., M.L.C., T.D., A.P., T.A.L., M.O., K.J.R.)., Pietrangelo A; From the University of Ottawa Heart Institute, ON, Canada (A.R., S.R., M.-A.N., M.G., H.W., M.L.C., T.D., A.P., T.A.L., M.O., K.J.R.)., Lee R; Cardiovascular Antisense Drug Discovery Group, Ionis Pharmaceuticals, Carlsbad, CA (R.L.)., Lagace TA; From the University of Ottawa Heart Institute, ON, Canada (A.R., S.R., M.-A.N., M.G., H.W., M.L.C., T.D., A.P., T.A.L., M.O., K.J.R.).; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, ON, Canada (S.R., M.-A.N., M.L.C., T.A.L., M.O., K.J.R.)., Ouimet M; From the University of Ottawa Heart Institute, ON, Canada (A.R., S.R., M.-A.N., M.G., H.W., M.L.C., T.D., A.P., T.A.L., M.O., K.J.R.).; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, ON, Canada (S.R., M.-A.N., M.L.C., T.A.L., M.O., K.J.R.)., Rayner KJ; From the University of Ottawa Heart Institute, ON, Canada (A.R., S.R., M.-A.N., M.G., H.W., M.L.C., T.D., A.P., T.A.L., M.O., K.J.R.).; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, ON, Canada (S.R., M.-A.N., M.L.C., T.A.L., M.O., K.J.R.).

المصدر: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 May; Vol. 40 (5), pp. 1155-1167. Date of Electronic Publication: 2020 Mar 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE

مواضيع طبية MeSH: Plaque, Atherosclerotic*, Aortic Diseases/*enzymology , Atherosclerosis/*enzymology , Cholesterol/*metabolism , Foam Cells/*enzymology , Macrophages, Peritoneal/*enzymology , Protein Kinases/*deficiency, Animals ; Aortic Diseases/genetics ; Aortic Diseases/pathology ; Atherosclerosis/genetics ; Atherosclerosis/pathology ; Disease Models, Animal ; Endosomes/metabolism ; Female ; Foam Cells/pathology ; Macrophages, Peritoneal/pathology ; Male ; Mice, Knockout, ApoE ; Necroptosis ; Necrosis ; Oligonucleotides, Antisense/administration & dosage ; Protein Kinases/genetics ; Receptor-Interacting Protein Serine-Threonine Kinases/genetics ; Receptor-Interacting Protein Serine-Threonine Kinases/metabolism ; Signal Transduction

المؤلفون: Nguyen MA; University of Ottawa Heart Institute , Ottawa , Ontario K1Y 4W7 , Canada., Wyatt H; University of Ottawa Heart Institute , Ottawa , Ontario K1Y 4W7 , Canada., Susser L; University of Ottawa Heart Institute , Ottawa , Ontario K1Y 4W7 , Canada., Geoffrion M; University of Ottawa Heart Institute , Ottawa , Ontario K1Y 4W7 , Canada., Rasheed A; University of Ottawa Heart Institute , Ottawa , Ontario K1Y 4W7 , Canada., Duchez AC; University of Ottawa Heart Institute , Ottawa , Ontario K1Y 4W7 , Canada., Cottee ML; University of Ottawa Heart Institute , Ottawa , Ontario K1Y 4W7 , Canada., Afolayan E; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine , University of Ottawa , Ottawa , Ontario K1H 8M5 , Canada., Farah E; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine , University of Ottawa , Ottawa , Ontario K1H 8M5 , Canada., Kahiel Z; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine , University of Ottawa , Ottawa , Ontario K1H 8M5 , Canada., Côté M; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine , University of Ottawa , Ottawa , Ontario K1H 8M5 , Canada., Gadde S; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine , University of Ottawa , Ottawa , Ontario K1H 8M5 , Canada., Rayner KJ; University of Ottawa Heart Institute , Ottawa , Ontario K1Y 4W7 , Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine , University of Ottawa , Ottawa , Ontario K1H 8M5 , Canada.

المصدر: ACS nano [ACS Nano] 2019 Jun 25; Vol. 13 (6), pp. 6491-6505. Date of Electronic Publication: 2019 Jun 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE

مواضيع طبية MeSH: Chitosan/*analogs & derivatives , Cholesterol/*metabolism , Macrophages, Peritoneal/*metabolism , MicroRNAs/*genetics , Nanoparticles/*chemistry , RNAi Therapeutics/*methods, ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter 1/metabolism ; Animals ; Cells, Cultured ; Cholesterol/blood ; Gene Transfer Techniques ; Liver/metabolism ; Mice ; Mice, Inbred C57BL ; MicroRNAs/metabolism