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المؤلفون: Shemtov SJ; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Buck Institute for Research on Aging, Novato, CA, USA., Emani R; Buck Institute for Research on Aging, Novato, CA, USA., Bielska O; Buck Institute for Research on Aging, Novato, CA, USA., Covarrubias AJ; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, CA, USA., Verdin E; Buck Institute for Research on Aging, Novato, CA, USA., Andersen JK; Buck Institute for Research on Aging, Novato, CA, USA., Winer DA; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Buck Institute for Research on Aging, Novato, CA, USA.; Division of Cellular & Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, ON, Canada.; Department of Immunology, University of Toronto, ON, Canada.

المصدر: The FEBS journal [FEBS J] 2023 Sep; Vol. 290 (17), pp. 4163-4186. Date of Electronic Publication: 2022 Jul 01.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2*, Humans ; Obesity/metabolism ; Inflammation ; Aging ; Liver/metabolism

المؤلفون: Jiang Y; Department of Computational Biomedicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.; Advanced Clinical Biosystems Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.; Smidt Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA., Salladay-Perez I; Department of Molecular Biology, Immunology, and Molecular Genetics, University of California, Los Angeles, 90095, USA., Momenzadeh A; Department of Computational Biomedicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.; Advanced Clinical Biosystems Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.; Smidt Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA., Covarrubias AJ; Department of Molecular Biology, Immunology, and Molecular Genetics, University of California, Los Angeles, 90095, USA., Meyer JG; Department of Computational Biomedicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.; Advanced Clinical Biosystems Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.; Smidt Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jun 29. Date of Electronic Publication: 2023 Jun 29.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Heckenbach I; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.; Buck Institute for Research on Aging, Novato, CA, USA.; Tracked.bio, Copenhagen, Denmark., Mkrtchyan GV; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Ezra MB; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.; Methods and Analysis, Statistics Denmark, Copenhagen, Denmark., Bakula D; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Madsen JS; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Nielsen MH; Gubra, Hørsholm, Denmark., Oró D; Gubra, Hørsholm, Denmark., Osborne B; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Covarrubias AJ; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA., Idda ML; Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, USA.; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Sassari, Italy., Gorospe M; Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, USA., Mortensen L; Methods and Analysis, Statistics Denmark, Copenhagen, Denmark.; Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Verdin E; Buck Institute for Research on Aging, Novato, CA, USA., Westendorp R; Methods and Analysis, Statistics Denmark, Copenhagen, Denmark.; Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Scheibye-Knudsen M; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark. mscheibye@sund.ku.dk.; Tracked.bio, Copenhagen, Denmark. mscheibye@sund.ku.dk.

المصدر: Nature aging [Nat Aging] 2022 Aug; Vol. 2 (8), pp. 742-755. Date of Electronic Publication: 2022 Aug 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group US Country of Publication: United States NLM ID: 101773306 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-8465 (Electronic) Linking ISSN: 26628465 NLM ISO Abbreviation: Nat Aging Subsets: MEDLINE

مواضيع طبية MeSH: Deep Learning* , Aging, Premature*, Humans ; Mice ; Animals ; Cellular Senescence/physiology ; Aging ; Biomarkers

المؤلفون: Bartleson JM; Buck Institute for Research on Aging, Novato, CA 94945, USA., Radenkovic D; Faculty of Life Sciences and Medicine, King's College London, London SE5 9NU, UK.; Hooke, Health, Longevity Optimisation, London W1J 5RG, UK., Covarrubias AJ; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095 USA.; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, 90095 USA., Furman D; Buck Institute for Research on Aging, Novato, CA 94945, USA.; These authors jointly supervised this work., Winer DA; Buck Institute for Research on Aging, Novato, CA 94945, USA.; These authors jointly supervised this work., Verdin E; Buck Institute for Research on Aging, Novato, CA 94945, USA.; These authors jointly supervised this work.

المصدر: Nature aging [Nat Aging] 2021 Sep; Vol. 1 (9), pp. 769-782. Date of Electronic Publication: 2021 Sep 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group US Country of Publication: United States NLM ID: 101773306 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-8465 (Electronic) Linking ISSN: 26628465 NLM ISO Abbreviation: Nat Aging

مواضيع طبية MeSH: Aging* , COVID-19*/immunology , Immunosenescence*, Humans ; Immune System ; SARS-CoV-2

المؤلفون: Covarrubias AJ; Buck Institute for Research on Aging, Novato, CA, USA.; UCSF Department of Medicine, San Francisco, CA, USA., Perrone R; Buck Institute for Research on Aging, Novato, CA, USA., Grozio A; Buck Institute for Research on Aging, Novato, CA, USA., Verdin E; Buck Institute for Research on Aging, Novato, CA, USA. everdin@buckinstitute.org.; UCSF Department of Medicine, San Francisco, CA, USA. everdin@buckinstitute.org.

المصدر: Nature reviews. Molecular cell biology [Nat Rev Mol Cell Biol] 2021 Feb; Vol. 22 (2), pp. 119-141. Date of Electronic Publication: 2020 Dec 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100962782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-0080 (Electronic) Linking ISSN: 14710072 NLM ISO Abbreviation: Nat Rev Mol Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Aging* , Cell Physiological Phenomena* , Metabolic Networks and Pathways*, Mitochondria/*metabolism , NAD/*metabolism, Animals ; Energy Metabolism ; Humans

المؤلفون: Covarrubias AJ; Buck Institute for Research on Aging, Novato, CA, USA.; UCSF Department of Medicine, San Francisco, CA, USA., Kale A; Buck Institute for Research on Aging, Novato, CA, USA., Perrone R; Buck Institute for Research on Aging, Novato, CA, USA., Lopez-Dominguez JA; Buck Institute for Research on Aging, Novato, CA, USA., Pisco AO; Chan Zuckerberg Biohub, San Francisco, CA, USA., Kasler HG; Buck Institute for Research on Aging, Novato, CA, USA., Schmidt MS; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Heckenbach I; Buck Institute for Research on Aging, Novato, CA, USA.; Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Kwok R; Buck Institute for Research on Aging, Novato, CA, USA., Wiley CD; Buck Institute for Research on Aging, Novato, CA, USA., Wong HS; Buck Institute for Research on Aging, Novato, CA, USA., Gibbs E; Buck Institute for Research on Aging, Novato, CA, USA., Iyer SS; Division of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Basisty N; Buck Institute for Research on Aging, Novato, CA, USA., Wu Q; Buck Institute for Research on Aging, Novato, CA, USA., Kim IJ; Buck Institute for Research on Aging, Novato, CA, USA., Silva E; Buck Institute for Research on Aging, Novato, CA, USA., Vitangcol K; Buck Institute for Research on Aging, Novato, CA, USA., Shin KO; College of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea.; Department of Food Science and Nutrition, Hallym University, Chuncheon, Republic of Korea., Lee YM; College of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea., Riley R; Buck Institute for Research on Aging, Novato, CA, USA., Ben-Sahra I; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA., Ott M; Gladstone Institutes, Virology and Immunology, San Francisco, CA, USA., Schilling B; Buck Institute for Research on Aging, Novato, CA, USA., Scheibye-Knudsen M; Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Ishihara K; Immunology and Molecular Genetics, Kawasaki Medical School, Kurashiki, Japan., Quake SR; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Department of Bioengineering, Stanford University, Stanford, CA, USA., Newman J; Buck Institute for Research on Aging, Novato, CA, USA.; UCSF Department of Medicine, San Francisco, CA, USA., Brenner C; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Department of Diabetes & Cancer Metabolism, City of Hope National Medical Center, Duarte, CA, USA., Campisi J; Buck Institute for Research on Aging, Novato, CA, USA., Verdin E; Buck Institute for Research on Aging, Novato, CA, USA. everdin@buckinstitute.org.; UCSF Department of Medicine, San Francisco, CA, USA. everdin@buckinstitute.org.

المصدر: Nature metabolism [Nat Metab] 2021 Jan; Vol. 3 (1), pp. 120-121.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Covarrubias AJ; Buck Institute for Research on Aging, Novato, CA, USA.; UCSF Department of Medicine, San Francisco, CA, USA., Kale A; Buck Institute for Research on Aging, Novato, CA, USA., Perrone R; Buck Institute for Research on Aging, Novato, CA, USA., Lopez-Dominguez JA; Buck Institute for Research on Aging, Novato, CA, USA., Pisco AO; Chan Zuckerberg Biohub, San Francisco, CA, USA., Kasler HG; Buck Institute for Research on Aging, Novato, CA, USA., Schmidt MS; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Heckenbach I; Buck Institute for Research on Aging, Novato, CA, USA.; Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Kwok R; Buck Institute for Research on Aging, Novato, CA, USA., Wiley CD; Buck Institute for Research on Aging, Novato, CA, USA., Wong HS; Buck Institute for Research on Aging, Novato, CA, USA., Gibbs E; Buck Institute for Research on Aging, Novato, CA, USA., Iyer SS; Division of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Basisty N; Buck Institute for Research on Aging, Novato, CA, USA., Wu Q; Buck Institute for Research on Aging, Novato, CA, USA., Kim IJ; Buck Institute for Research on Aging, Novato, CA, USA., Silva E; Buck Institute for Research on Aging, Novato, CA, USA., Vitangcol K; Buck Institute for Research on Aging, Novato, CA, USA., Shin KO; College of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea.; Department of Food Science and Nutrition, Hallym University, Chuncheon, Republic of Korea., Lee YM; College of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea., Riley R; Buck Institute for Research on Aging, Novato, CA, USA., Ben-Sahra I; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA., Ott M; Gladstone Institutes, Virology and Immunology, San Francisco, CA, USA., Schilling B; Buck Institute for Research on Aging, Novato, CA, USA., Scheibye-Knudsen M; Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Ishihara K; Immunology and Molecular Genetics, Kawasaki Medical School, Kurashiki, Japan., Quake SR; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Department of Bioengineering, Stanford University, Stanford, CA, USA., Newman J; Buck Institute for Research on Aging, Novato, CA, USA.; UCSF Department of Medicine, San Francisco, CA, USA., Brenner C; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Department of Diabetes & Cancer Metabolism, City of Hope National Medical Center, Duarte, CA, USA., Campisi J; Buck Institute for Research on Aging, Novato, CA, USA., Verdin E; Buck Institute for Research on Aging, Novato, CA, USA. everdin@buckinstitute.org.; UCSF Department of Medicine, San Francisco, CA, USA. everdin@buckinstitute.org.

المصدر: Nature metabolism [Nat Metab] 2020 Nov; Vol. 2 (11), pp. 1265-1283. Date of Electronic Publication: 2020 Nov 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE

مواضيع طبية MeSH: Cellular Senescence* , Macrophage Activation*, ADP-ribosyl Cyclase 1/*genetics , Aging/*metabolism , Membrane Glycoproteins/*genetics , NAD/*metabolism, ADP-ribosyl Cyclase/metabolism ; Adipose Tissue, White/metabolism ; Animals ; Antigens, CD/metabolism ; Cytokines/metabolism ; Female ; GPI-Linked Proteins/metabolism ; Gene Expression ; Glycolysis/genetics ; Humans ; Liver/metabolism ; Male ; Metabolome ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/metabolism ; NAD+ Nucleosidase/metabolism

المؤلفون: Newman JC; Buck Institute for Research on Aging, Novato, CA 94945, USA; UCSF Division of Geriatrics, San Francisco, CA 94118, USA; Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA., Covarrubias AJ; Buck Institute for Research on Aging, Novato, CA 94945, USA., Zhao M; UCSF Global Health Sciences, San Francisco, CA 94158, USA., Yu X; UCSF Division of Geriatrics, San Francisco, CA 94118, USA., Gut P; Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA., Ng CP; Buck Institute for Research on Aging, Novato, CA 94945, USA., Huang Y; Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA., Haldar S; Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA., Verdin E; Buck Institute for Research on Aging, Novato, CA 94945, USA; UCSF Division of Geriatrics, San Francisco, CA 94118, USA; Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA. Electronic address: everdin@buckinstitute.org.

المصدر: Cell metabolism [Cell Metab] 2017 Sep 05; Vol. 26 (3), pp. 547-557.e8.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE

مواضيع طبية MeSH: Diet, Ketogenic* , Mortality*, Aging/*physiology , Memory/*physiology, Animals ; Diet, High-Fat ; Fasting ; Gene Expression Regulation ; Liver/metabolism ; Male ; Mice, Inbred C57BL ; PPAR alpha/genetics ; PPAR alpha/metabolism

المؤلفون: Covarrubias AJ; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, United States., Aksoylar HI; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, United States., Yu J; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, United States., Snyder NW; Center of Excellence in Environmental Toxicology, University of Pennsylvania, Philadelphia, United States.; A.J. Drexel Autism Institute, Drexel University, Philadelphia, United States., Worth AJ; Center of Excellence in Environmental Toxicology, University of Pennsylvania, Philadelphia, United States., Iyer SS; Department of Medicine, Brigham and Women's Hospital, Boston, United States., Wang J; Institute for Plant Physiology and Ecology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai, China., Ben-Sahra I; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, United States., Byles V; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, United States., Polynne-Stapornkul T; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, United States., Espinosa EC; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, United States., Lamming D; Department of Medicine, University of Wisconsin-Madison, Madison, United States., Manning BD; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, United States., Zhang Y; Institute for Plant Physiology and Ecology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai, China., Blair IA; Center of Excellence in Environmental Toxicology, University of Pennsylvania, Philadelphia, United States., Horng T; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, United States.

المصدر: ELife [Elife] 2016 Feb 19; Vol. 5. Date of Electronic Publication: 2016 Feb 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Macrophage Activation* , Signal Transduction*, ATP Citrate (pro-S)-Lyase/*metabolism , Macrophages/*metabolism , Multiprotein Complexes/*metabolism , Proto-Oncogene Proteins c-akt/*metabolism , TOR Serine-Threonine Kinases/*metabolism, Acetylation ; Animals ; Cell Proliferation ; Chemokines/metabolism ; Gene Expression Regulation ; Histones/metabolism ; Interleukin-4/metabolism ; Macrophages/physiology ; Mechanistic Target of Rapamycin Complex 1 ; Mice, Inbred C57BL ; Protein Processing, Post-Translational