المؤلفون: Anand RP; eGenesis, Cambridge, MA, USA., Layer JV; eGenesis, Cambridge, MA, USA., Heja D; eGenesis, Cambridge, MA, USA., Hirose T; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Lassiter G; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Firl DJ; eGenesis, Cambridge, MA, USA.; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Paragas VB; eGenesis, Cambridge, MA, USA., Akkad A; eGenesis, Cambridge, MA, USA., Chhangawala S; eGenesis, Cambridge, MA, USA., Colvin RB; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Ernst RJ; eGenesis, Cambridge, MA, USA., Esch N; eGenesis, Cambridge, MA, USA., Getchell K; eGenesis, Cambridge, MA, USA., Griffin AK; eGenesis, Cambridge, MA, USA., Guo X; eGenesis, Cambridge, MA, USA., Hall KC; eGenesis, Cambridge, MA, USA., Hamilton P; eGenesis, Cambridge, MA, USA., Kalekar LA; eGenesis, Cambridge, MA, USA., Kan Y; eGenesis, Cambridge, MA, USA., Karadagi A; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Li F; eGenesis, Cambridge, MA, USA., Low SC; eGenesis, Cambridge, MA, USA., Matheson R; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Nehring C; eGenesis, Cambridge, MA, USA., Otsuka R; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Pandelakis M; eGenesis, Cambridge, MA, USA., Policastro RA; eGenesis, Cambridge, MA, USA., Pols R; eGenesis, Cambridge, MA, USA., Queiroz L; eGenesis, Cambridge, MA, USA., Rosales IA; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Serkin WT; eGenesis, Cambridge, MA, USA., Stiede K; eGenesis, Cambridge, MA, USA., Tomosugi T; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Xue Y; eGenesis, Cambridge, MA, USA., Zentner GE; eGenesis, Cambridge, MA, USA., Angeles-Albores D; eGenesis, Cambridge, MA, USA., Chris Chao J; eGenesis, Cambridge, MA, USA., Crabtree JN; eGenesis, Cambridge, MA, USA., Harken S; eGenesis, Cambridge, MA, USA., Hinkle N; eGenesis, Cambridge, MA, USA., Lemos T; eGenesis, Cambridge, MA, USA., Li M; eGenesis, Cambridge, MA, USA., Pantano L; eGenesis, Cambridge, MA, USA., Stevens D; eGenesis, Cambridge, MA, USA., Subedar OD; eGenesis, Cambridge, MA, USA., Tan X; eGenesis, Cambridge, MA, USA., Yin S; eGenesis, Cambridge, MA, USA., Anwar IJ; Duke Transplant Center, Department of Surgery, Duke University Medical Center, Durham, NC, USA., Aufhauser D; Department of Surgery, Division of Transplantation, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., Capuano S; Wisconsin National Primate Research Center, Madison, WI, USA., Kaufman DB; Department of Surgery, Division of Transplantation, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., Knechtle SJ; Duke Transplant Center, Department of Surgery, Duke University Medical Center, Durham, NC, USA., Kwun J; Duke Transplant Center, Department of Surgery, Duke University Medical Center, Durham, NC, USA., Shanmuganayagam D; Department of Animal and Dairy Science, University of Wisconsin, Madison, WI, USA., Markmann JF; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Church GM; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Wyss Institute of Biologically Inspired Engineering, Harvard University, Cambridge, MA, USA., Curtis M; eGenesis, Cambridge, MA, USA., Kawai T; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Youd ME; eGenesis, Cambridge, MA, USA. michele.youd@egenesisbio.com., Qin W; eGenesis, Cambridge, MA, USA. wenning.qin@egenesisbio.com.

المصدر: Nature [Nature] 2023 Oct; Vol. 622 (7982), pp. 393-401. Date of Electronic Publication: 2023 Oct 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Graft Rejection*/immunology , Graft Rejection*/prevention & control , Kidney Transplantation*/methods , Macaca fascicularis* , Swine*/genetics , Transplantation, Heterologous*/methods, Animals ; Humans ; Animals, Genetically Modified ; Endothelial Cells/immunology ; Endothelial Cells/metabolism ; Polysaccharides/deficiency ; Transgenes/genetics

المؤلفون: Petitpas K; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Habibabady Z; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Ritchie V; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Connolly MR; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Burdorf L; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Qin W; eGenesis Inc., Cambridge, Massachusetts, USA., Kan Y; eGenesis Inc., Cambridge, Massachusetts, USA., Layer JV; eGenesis Inc., Cambridge, Massachusetts, USA., Crabtree JN; eGenesis Inc., Cambridge, Massachusetts, USA., Youd ME; eGenesis Inc., Cambridge, Massachusetts, USA., Westlin WF; eGenesis Inc., Cambridge, Massachusetts, USA., Magnani DM; MassBiologics of UMMS, Boston, Massachusetts, USA., Pierson RN 3rd; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Azimzadeh AM; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA.

المصدر: Xenotransplantation [Xenotransplantation] 2022 Nov; Vol. 29 (6), pp. e12780. Date of Electronic Publication: 2022 Sep 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Munksgaard International Publishers Country of Publication: Denmark NLM ID: 9438793 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-3089 (Electronic) Linking ISSN: 0908665X NLM ISO Abbreviation: Xenotransplantation Subsets: MEDLINE

مواضيع طبية MeSH: Sialic Acid Binding Ig-like Lectin 1*/genetics , N-Acetylneuraminic Acid*/metabolism, Humans ; Swine ; Animals ; Transplantation, Heterologous/methods ; Macrophages ; Erythrocytes/metabolism

المؤلفون: Crabtree JN; Program in Innate Immunity and.; Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Caffrey DR; Program in Innate Immunity and.; Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., de Souza Silva L; Program in Innate Immunity and.; Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Kurt-Jones EA; Program in Innate Immunity and.; Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Dobbs K; Case Western University, Cleveland, Ohio, USA., Dent A; Case Western University, Cleveland, Ohio, USA., Fitzgerald KA; Program in Innate Immunity and.; Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Golenbock DT; Program in Innate Immunity and.; Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

المصدر: The Journal of clinical investigation [J Clin Invest] 2022 Jun 01; Vol. 132 (11).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Lymphocytes*/immunology , Malaria, Falciparum*/immunology , Monocytes*/immunology, Chromatin ; Humans ; Interleukin-6/genetics ; Plasmodium falciparum ; Tumor Necrosis Factor-alpha/metabolism

المؤلفون: Dobbs KR; Center for Global Health and Diseases, Case Western Reserve University, Cleveland, OH, USA.; Division of Pediatric Infectious Diseases, University Hospitals Rainbow Babies and Children's Hospital, Cleveland, OH, USA., Crabtree JN; Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA., Dent AE; Center for Global Health and Diseases, Case Western Reserve University, Cleveland, OH, USA.; Division of Pediatric Infectious Diseases, University Hospitals Rainbow Babies and Children's Hospital, Cleveland, OH, USA.

المصدر: Immunological reviews [Immunol Rev] 2020 Jan; Vol. 293 (1), pp. 8-24. Date of Electronic Publication: 2019 Dec 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-065X (Electronic) Linking ISSN: 01052896 NLM ISO Abbreviation: Immunol Rev Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Innate*, Host-Parasite Interactions/*immunology , Malaria/*immunology , Malaria/*parasitology , Monocytes/*immunology , Plasmodium/*immunology, Biomarkers ; Cytokines/metabolism ; Energy Metabolism ; Epigenesis, Genetic ; Female ; Host-Parasite Interactions/genetics ; Humans ; Immune Tolerance ; Immunophenotyping ; Inflammation Mediators/metabolism ; Leukocyte Count ; Macrophages/immunology ; Macrophages/metabolism ; Macrophages/parasitology ; Malaria/genetics ; Malaria/metabolism ; Monocytes/metabolism ; Organ Specificity ; Phagocytosis/immunology ; Pregnancy ; Pregnancy Complications, Parasitic

المؤلفون: Schrum JE; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605., Crabtree JN; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605., Dobbs KR; Department of Pediatrics, Rainbow Babies and Children's Hospital, Cleveland, OH 44106., Kiritsy MC; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605., Reed GW; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605.; Corrona, LLC, Southborough, MA 01772., Gazzinelli RT; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605.; Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 41270-901, Brazil.; Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Minas Gerais 30190-002, Brazil., Netea MG; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands; and., Kazura JW; Center for Global Health and Disease, Case Western Reserve University, Cleveland, OH 44106., Dent AE; Department of Pediatrics, Rainbow Babies and Children's Hospital, Cleveland, OH 44106.; Center for Global Health and Disease, Case Western Reserve University, Cleveland, OH 44106., Fitzgerald KA; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605., Golenbock DT; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605; douglas.golenbock@umassmed.edu.

المصدر: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2018 Feb 15; Vol. 200 (4), pp. 1243-1248. Date of Electronic Publication: 2018 Jan 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association of Immunologists Country of Publication: United States NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Innate/*immunology , Malaria, Falciparum/*immunology, Child ; Child, Preschool ; Epigenesis, Genetic/immunology ; Female ; Gene Expression Regulation/immunology ; Histones/biosynthesis ; Humans ; Infant ; Malaria, Falciparum/metabolism ; Male

المؤلفون: Tien SH; Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, Minnesota, United States of America., Crabtree JN; Center for Immunology and Division of Rheumatic and Autoimmune Diseases, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America., Gray HL; Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, Minnesota, United States of America., Peterson EJ; Center for Immunology and Division of Rheumatic and Autoimmune Diseases, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America.

المصدر: PloS one [PLoS One] 2017 Jul 19; Vol. 12 (7), pp. e0181338. Date of Electronic Publication: 2017 Jul 19 (Print Publication: 2017).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Influenza Vaccines/*immunology , Influenza, Human/*prevention & control , Protein Tyrosine Phosphatase, Non-Receptor Type 22/*genetics, Adult ; Antibodies, Neutralizing ; CD4-Positive T-Lymphocytes/immunology ; Female ; Hemagglutination Inhibition Tests ; Humans ; Pregnancy

المؤلفون: Crabtree JN; Center for Immunology Division of Rheumatic and Autoimmune Diseases, Department of Medicine, University of Minnesota Medical School., He W; Department of Microbiology, School of Graduate Studies, Icahn School of Medicine at Mount Sinai, New York, New York., Guan W; Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis., Flage M; Center for Immunology., Miller MS; Department of Biochemistry and Biomedical Sciences, Institute for Infectious Diseases Research, McMaster Immunology Research Center, McMaster University, Hamilton, Canada., Peterson EJ; Center for Immunology Division of Rheumatic and Autoimmune Diseases, Department of Medicine, University of Minnesota Medical School.

المصدر: The Journal of infectious diseases [J Infect Dis] 2016 Jul 15; Vol. 214 (2), pp. 248-57. Date of Electronic Publication: 2016 Mar 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Adaptive Immunity* , Immunity, Innate*, Antibodies, Viral/*blood , Influenza Vaccines/*immunology , Orthomyxoviridae/*immunology , Protein Tyrosine Phosphatase, Non-Receptor Type 22/*genetics, Adolescent ; Adult ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Female ; Humans ; Male ; Middle Aged ; Mutant Proteins/genetics ; Young Adult

المؤلفون: Wang Y; University of Minnesota, Minneapolis., Ewart D; University of Minnesota, Minneapolis., Crabtree JN; University of Minnesota, Minneapolis., Yamamoto A; University of Minnesota, Minneapolis., Baechler EC; University of Minnesota, Minneapolis., Fazeli P; University of Minnesota, Minneapolis., Peterson EJ; University of Minnesota, Minneapolis.

المصدر: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2015 Sep; Vol. 67 (9), pp. 2403-14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101623795 Publication Model: Print Cited Medium: Internet ISSN: 2326-5205 (Electronic) Linking ISSN: 23265191 NLM ISO Abbreviation: Arthritis Rheumatol Subsets: MEDLINE

مواضيع طبية MeSH: Interferon-alpha/*immunology , Lupus Erythematosus, Systemic/*genetics , Membrane Glycoproteins/*immunology , Protein Tyrosine Phosphatase, Non-Receptor Type 22/*genetics , Toll-Like Receptor 7/*immunology, Adult ; Animals ; Case-Control Studies ; Dendritic Cells/immunology ; Female ; Gene Expression Profiling ; Gene Expression Regulation ; Humans ; Imidazoles/pharmacology ; Interferon Type I/immunology ; Leukocytes, Mononuclear/immunology ; Lupus Erythematosus, Systemic/immunology ; Membrane Glycoproteins/agonists ; Mice, Transgenic ; Middle Aged ; Polymorphism, Single Nucleotide ; STAT1 Transcription Factor/immunology ; Toll-Like Receptor 7/agonists ; Tumor Necrosis Factor-alpha

المؤلفون: Crabtree JN; Department of Microbiology, Medical School, University of Minnesota, Minneapolis, Minnesota, USA., Okagaki LH, Wiesner DL, Strain AK, Nielsen JN, Nielsen K

المصدر: Infection and immunity [Infect Immun] 2012 Nov; Vol. 80 (11), pp. 3776-85. Date of Electronic Publication: 2012 Aug 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0246127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5522 (Electronic) Linking ISSN: 00199567 NLM ISO Abbreviation: Infect Immun Subsets: MEDLINE

مواضيع طبية MeSH: Host-Pathogen Interactions*, Cryptococcosis/*immunology , Cryptococcus neoformans/*pathogenicity , Fungal Proteins/*immunology , Lung/*immunology , Virulence Factors/*immunology, Animals ; Cells, Cultured ; Cryptococcosis/pathology ; Cryptococcus neoformans/genetics ; Cryptococcus neoformans/physiology ; Female ; Mice ; Mice, Inbred C57BL ; Phagocytosis