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المؤلفون: Orly Leiva, Alison D. Findlay, Shinobu Matsuura, Vipul C. Chitalia, Hector A. Lucero, Seng Kah Ng, Wolfgang Jarolimek, Katya Ravid, Craig Ivan Turner
المصدر: Int J Hematol
مصطلحات موضوعية: Male, Ruxolitinib, Biological Availability, Lysyl oxidase, Pharmacology, Article, Protein-Lysine 6-Oxidase, Mice, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Megakaryocyte, Fibrosis, Animals, Medicine, Enzyme Inhibitors, Myelofibrosis, Myeloproliferative neoplasm, business.industry, Hematology, medicine.disease, Transplantation, Disease Models, Animal, Treatment Outcome, medicine.anatomical_structure, Primary Myelofibrosis, 030220 oncology & carcinogenesis, Female, Bone marrow, Bone Marrow Neoplasms, business, 030215 immunology, medicine.drug
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المؤلفون: Zhou Wenbin, Mary Brock, Heidi Schilter, Mandar Deodhar, Lara Perryman, Jessica Stolp, Craig Ivan Turner, Dieter Hamprecht, Brett Charlton, Yimin Yao, Wolfgang Jarolimek, Christina Raso, Ross Hamilton, Jonathan Stuart Foot, Marie Galati, Alison D. Findlay, Amna Zahoor
المصدر: Clinical and Translational Medicine, Vol 11, Iss 11, Pp n/a-n/a (2021)
Clinical and Translational Medicineمصطلحات موضوعية: Anti fibrotic, Medicine (General), LOXL2, biology, Chemistry, Medicine (miscellaneous), Biosensing Techniques, Letter to Editor, Small molecule, Fibrosis, R5-920, biology.protein, Cancer research, Molecular Medicine, Humans, Amino Acid Oxidoreductases, Antibody, Antifibrotic Agents
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المؤلفون: Dieter Hamprecht, Alison D. Findlay, Craig Ivan Turner
المصدر: Anti-fibrotic Drug Discovery ISBN: 9781788015103
مصطلحات موضوعية: chemistry.chemical_classification, LOXL3, LOXL2, biology, Lysyl oxidase, medicine.disease, Enzyme assay, Collagen formation, Enzyme, chemistry, Biochemistry, Fibrosis, medicine, biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d159c3af0e387ba4e968c189bceb4887
https://doi.org/10.1039/9781788015783-00145 -
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المؤلفون: Wolfgang Jarolimek, Andrew G. Jarnicki, Heidi Schilter, Jonathan Stuart Foot, Philip M. Hansbro, Craig Ivan Turner, Zhou Wenbin, Mandar Deodhar, Gang Liu, Alison D. Findlay, Alberto Buson
المصدر: Journal of medicinal chemistry. 62(21)
مصطلحات موضوعية: Amine oxidase, Lysyl oxidase, 01 natural sciences, Extracellular matrix, Protein-Lysine 6-Oxidase, 03 medical and health sciences, Mice, Drug Discovery, Animals, Humans, Amines, Enzyme Inhibitors, 030304 developmental biology, chemistry.chemical_classification, Indole test, 0303 health sciences, LOXL3, LOXL2, biology, Chemistry, Triazoles, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Biochemistry, Drug Design, biology.protein, Molecular Medicine, Elastin
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المؤلفون: Amna Zahoor, Craig Ivan Turner, Heidi Schilter, Greco Angelique Elsa, Joshua Moses, Tin T Yow, Wolfgang Jarolimek, Zhou Wenbin, Mandar Deodhar, Alberto Buson, Sarah Townsend, Lara Perryman, Benjamin S. Rayner, Jonathan Stuart Foot, Alison D. Findlay, Amar Joshi
المصدر: Journal of Cellular and Molecular Medicine
مصطلحات موضوعية: 0301 basic medicine, Male, collagen crosslinking, Myocardial Infarction, Lysyl oxidase, macromolecular substances, Extracellular matrix, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Fibrosis, Non-alcoholic Fatty Liver Disease, medicine, Animals, Enzyme Inhibitors, Rats, Wistar, Carbon Tetrachloride, PXS‐5153A, LOXL3, biology, LOXL2, fibrosis, technology, industry, and agriculture, Cell Biology, Original Articles, medicine.disease, Cell biology, Elastin, Extracellular Matrix, Rats, Mice, Inbred C57BL, Hydroxylysine, 030104 developmental biology, Cross-Linking Reagents, chemistry, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Original Article, Liver function, Amino Acid Oxidoreductases, Collagen, lysyl oxidase
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المؤلفون: Heidi Schilter, Alberto Buson, Craig Ivan Turner, Wolfgang Jarolimek, Zhou Wenbin, Mandar Deodhar, Tin T Yow, Lily Guo, Ian A. McDonald, Alison D. Findlay, Jonathan Stuart Foot
المصدر: The Journal of pharmacology and experimental therapeutics. 347(2)
مصطلحات موضوعية: Amine oxidase, medicine.drug_class, Anti-Inflammatory Agents, Inflammation, Dermatitis, Pharmacology, In Vitro Techniques, Models, Biological, Anti-inflammatory, Small Molecule Libraries, Mice, Dogs, Species Specificity, In vivo, Microsomes, medicine, Animals, Humans, Enzyme Inhibitors, Receptor, chemistry.chemical_classification, Sulfonamides, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Pneumonia, In vitro, Rats, Allyl Compounds, Disease Models, Animal, Enzyme, Adipose Tissue, Molecular Medicine, Tumor necrosis factor alpha, Amine Oxidase (Copper-Containing), Rabbits, medicine.symptom, Cell Adhesion Molecules
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7e32ac2b8611d88d7d111246c897af
https://pubmed.ncbi.nlm.nih.gov/23943052 -
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المؤلفون: Andrew Holt, Jonathan S. Foot, Craig Ivan Turner, Aldo Olivieri, Ian A. McDonald, Diego Silva, Ellen M. van Dam, Mandar Deodhar, Ping Yin
المصدر: Bioorganicmedicinal chemistry letters. 22(12)
مصطلحات موضوعية: Models, Molecular, Amine oxidase, Monoamine Oxidase Inhibitors, Halogenation, Clinical Biochemistry, Anti-Inflammatory Agents, Pharmaceutical Science, Inflammation, Biochemistry, Mice, Structure-Activity Relationship, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, Amines, Molecular Biology, Chemistry, Drug discovery, Organic Chemistry, Pneumonia, Rats, Allyl Compounds, Isoenzymes, Molecular Medicine, Amine gas treating, Amine Oxidase (Copper-Containing), medicine.symptom, Diamine oxidase, Selectivity