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1
المؤلفون: Naiyu Zheng, Oscar Puig, Craig Titsch, Zheng Ouyang, Renuka Pillutla, Jianing Zeng, Yang J Zhang, Rasa Santockyte
المصدر: Analytical chemistry. 93(2)
مصطلحات موضوعية: medicine.drug_class, Immunoglobulins, Antineoplastic Agents, 010402 general chemistry, Immunoglobulin light chain, Mass spectrometry, Monoclonal antibody, Interference (wave propagation), Antibodies, Monoclonal, Humanized, 01 natural sciences, Sensitivity and Specificity, Mass Spectrometry, Analytical Chemistry, medicine, Humans, Elotuzumab, Throughput (business), Multiple myeloma, Chromatography, biology, Chemistry, 010401 analytical chemistry, medicine.disease, 0104 chemical sciences, High-Throughput Screening Assays, biology.protein, Antibody, Multiple Myeloma, medicine.drug, Chromatography, Liquid
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2
المؤلفون: Jonathan Haulenbeek, Kelli R. Phillips, Ross Fergus, Hao Jiang, Craig Titsch, Frank Zambito, Janice Gambardella, Heather Myler, Jennifer Cummings, Alex Kozhich
المصدر: The AAPS Journal. 19:1461-1468
مصطلحات موضوعية: Accuracy and precision, Bioanalysis, Chromatography, medicine.drug_class, Chemistry, Coefficient of variation, Ligand binding assay, Microfluidics, 010401 analytical chemistry, Antibodies, Monoclonal, Pharmaceutical Science, Pharmacology, Ligands, Monoclonal antibody, 030226 pharmacology & pharmacy, 01 natural sciences, System a, 0104 chemical sciences, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Clinical case, Early phase
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المؤلفون: R. Marcus Fancher, Prasad Krishnamurthy, Tongtong Liu, Xi Qiu, Cliff Chen, Hamza Kandoussi, Kristin Taylor, Sunil Sukrutharaj, Kathy Kuit, Jianing Zeng, Yurong Lai, A. David Rodrigues, Hao Jiang, Gabe Mintier, Craig Titsch, Hong Shen, Punit Marathe
المصدر: Drug Metabolism and Disposition. 44:238-249
مصطلحات موضوعية: 0301 basic medicine, Organic Cation Transport Proteins, Pharmaceutical Science, Pharmacology, Biology, Kidney, 030226 pharmacology & pharmacy, Cell Line, 03 medical and health sciences, 0302 clinical medicine, In vivo, Cations, medicine, Animals, Humans, Drug Interactions, Organic cation transport proteins, HEK 293 cells, Kidney metabolism, Transporter, Metformin, In vitro, Kinetics, Macaca fascicularis, HEK293 Cells, Pyrimethamine, 030104 developmental biology, medicine.anatomical_structure, Renal physiology, biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f1439b649c45f5a1763a27d77a5338
https://doi.org/10.1124/dmd.115.066852 -
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المؤلفون: Snaehal Gadkari, Kristina D. Chadwick, Alicja Batog, Weifeng Xu, Renuka Pillutla, Jennifer Wheeler, Binodh DeSilva, Craig Titsch, Bonnie Wang, Heather Myler, Chris M. Thompson, James Stahl, Robert Dodge, Lauren Hippeli, Hao Jiang, Scott Willett, Brent Yamamoto
المصدر: Bioanalysis. 10(16)
مصطلحات موضوعية: 0301 basic medicine, Drug, Biodistribution, Bioanalysis, Pentamer, media_common.quotation_subject, Clinical Biochemistry, Ligands, 030226 pharmacology & pharmacy, Analytical Chemistry, law.invention, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, law, Liquid chromatography–mass spectrometry, Tandem Mass Spectrometry, Toxicity Tests, Animals, Humans, Amino Acid Sequence, General Pharmacology, Toxicology and Pharmaceutics, media_common, Chemistry, Ligand binding assay, General Medicine, Medical Laboratory Technology, 030104 developmental biology, Biochemistry, Pharmaceutical Preparations, Recombinant DNA, Biological Assay, Chromatography, Liquid
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المؤلفون: Jonathan Haulenbeek, Hao Jiang, Jianing Zeng, Renuka Pillutla, Robert Dodge, Binodh DeSilva, Weifeng Xu, Craig Titsch, Mark E. Arnold, Anne-Françoise Aubry
المصدر: Journal of Immunological Methods. 416:94-104
مصطلحات موضوعية: Serum, Drug, medicine.drug_class, media_common.quotation_subject, Immunology, Cross Reactions, Monoclonal antibody, Immunoglobulin G, Mice, Immune system, Neutralization Tests, Cell Line, Tumor, medicine, Animals, Humans, Immunology and Allergy, Bioassay, Neutralizing antibody, media_common, biology, Chemistry, Immunogenicity, Antibodies, Monoclonal, Antibodies, Neutralizing, Molecular biology, Antibody Formation, biology.protein, Biological Assay, Antibody
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المؤلفون: Alban Allentoff, Craig Titsch, Anne-Françoise Aubry, Dharmesh D. Desai, Billy Akinsanya, Binodh DeSilva, Hao Jiang, Hong Wu Shen, Kimberly Voronin, Jianing Zeng, Linlin Luo, Mark E. Arnold
المصدر: Analytical Chemistry. 85:9859-9867
مصطلحات موضوعية: Protein Denaturation, Time Factors, Formic acid, medicine.drug_class, Peptide, Tandem mass spectrometry, Monoclonal antibody, Analytical Chemistry, chemistry.chemical_compound, Tandem Mass Spectrometry, medicine, Animals, Chemical Precipitation, Humans, Trypsin, chemistry.chemical_classification, Chromatography, Chemistry, Antibodies, Monoclonal, Blood proteins, Amino acid, Macaca fascicularis, Biochemistry, Iodoacetamide, Feasibility Studies, Blood Chemical Analysis, Chromatography, Liquid, medicine.drug
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7
المؤلفون: Latha Sridharan, Judy Lucas, Carlo Etienne, Craig Titsch, Inder Chaudhary, Christine Huselton, Diane H. Boschelli, Jennifer M. Golas, Carolyn Discafani, Erwin R. Boghaert, Frank Boschelli, K T Arndt, Jonathan Golas, Fei Ye, Fangbiao Li
المصدر: Cancer Research. 65:5358-5364
مصطلحات موضوعية: Cancer Research, Colorectal cancer, Administration, Oral, Mice, Nude, Antineoplastic Agents, Biology, Focal adhesion, Mice, In vivo, Nitriles, medicine, Animals, Humans, Phosphorylation, Protein Kinase Inhibitors, Aniline Compounds, ABL, Kinase, Autophosphorylation, HCT116 Cells, medicine.disease, Xenograft Model Antitumor Assays, In vitro, src-Family Kinases, Oncology, Colonic Neoplasms, Quinolines, Cancer research, Female, HT29 Cells, Proto-oncogene tyrosine-protein kinase Src
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8dbf321e875be4b51a22f7f06ec9d92
https://doi.org/10.1158/0008-5472.can-04-2484 -
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المؤلفون: Mohammed Jemal, Weifeng Xu, Michael T. Furlong, Jianing Zeng, Hao Jiang, Craig Titsch
المصدر: Bioanalysis. 6(13)
مصطلحات موضوعية: Drug, Bioanalysis, medicine.drug_class, media_common.quotation_subject, Clinical Biochemistry, Molecular Sequence Data, Pharmacology, Monoclonal antibody, Analytical Chemistry, Tandem Mass Spectrometry, Lc ms ms, medicine, Humans, Trypsin, Amino Acid Sequence, General Pharmacology, Toxicology and Pharmaceutics, Chromatography, High Pressure Liquid, media_common, Human studies, Chemistry, Antibodies, Monoclonal, Amino acid substitution, General Medicine, Serum samples, Protein Structure, Tertiary, Medical Laboratory Technology, Amino Acid Substitution, Immunoglobulin G, Calibration, Hinge region, Immunoglobulin Heavy Chains, Peptides
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المؤلفون: Mark E. Arnold, Binodh DeSilva, Alban Allentoff, Jianing Zeng, Anne-Françoise Aubry, Kimberly Voronin, Robert Dodge, Michael T. Furlong, Hao Jiang, Weifeng Xu, Craig Titsch
المصدر: Analytical chemistry. 86(5)
مصطلحات موضوعية: Drug, medicine.drug_class, media_common.quotation_subject, Endogeny, Enzyme-Linked Immunosorbent Assay, Monoclonal antibody, Tandem mass spectrometry, Analytical Chemistry, Tandem Mass Spectrometry, medicine, Humans, Neutralizing antibody, media_common, Detection limit, biology, Chemistry, Immunogenicity, Reference Standards, Molecular biology, Antibodies, Neutralizing, Pharmaceutical Preparations, Immunoglobulin G, Calibration, biology.protein, Antibody, Chromatography, Liquid
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المؤلفون: Mark E. Arnold, Jianing Zeng, Richard C. Burrell, Anne-Françoise Aubry, Hao Jiang, Craig Titsch, Hamza Kandoussi, John A. Easter, Huidong Gu, Marc Bifano, Wenying Li
المصدر: Analytical chemistry. 84(22)
مصطلحات موضوعية: musculoskeletal diseases, Drug, Bioanalysis, Pyrrolidines, Microdosing, media_common.quotation_subject, Biological Availability, Pharmacology, Mass spectrometry, Mass Spectrometry, Analytical Chemistry, Therapeutic index, MicroDose, Humans, media_common, Chromatography, Chemistry, Selected reaction monitoring, Imidazoles, Reproducibility of Results, Valine, Drug Design, Isotope Labeling, Administration, Intravenous, Carbamates, Accelerator mass spectrometry