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1دورية أكاديمية
المؤلفون: Creina Slator, Zara Molphy, Vickie McKee, Andrew Kellett
المصدر: Redox Biology, Vol 12, Iss , Pp 150-161 (2017)
مصطلحات موضوعية: Medicine (General), R5-920, Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: Gianluca Toniolo, Vickie McKee, Nicoló Zuin Fantoni, Zara Molphy, George Mitrikas, Andrew Kellett, Chryssostomos Chatgilialoglu, Georgia Menounou, Creina Slator
المساهمون: Zuin Fantoni, Nicoló, Molphy, Zara, Slator, Creina, Menounou, Georgia, Toniolo, Gianluca, Mitrikas, George, McKee, Vickie, Chatgilialoglu, Chryssostomo, Kellett, Andrew
المصدر: Chemistry-A European Journal 25 (2019): 221–237. doi:10.1002/chem.201804084
info:cnr-pdr/source/autori:Zuin Fantoni N.; Molphy Z.; Slator C.; Menounou G.; Toniolo G.; Mitrikas G.; McKee V.; Chatgilialoglu C.; Kellett A./titolo:Polypyridyl-Based Copper Phenanthrene Complexes: A New Type of Stabilized Artificial Chemical Nuclease/doi:10.1002%2Fchem.201804084/rivista:Chemistry-A European Journal/anno:2019/pagina_da:221/pagina_a:237/intervallo_pagine:221–237/volume:25
Chemistry-A European Journal
Zuin Fantoni, N, Molphy, Z, Slator, C, Menounou, G, Toniolo, G, Mitrikas, G, McKee, V, Chatgilialoglu, C & Kellett, A 2019, ' Polypyridyl-Based Copper Phenanthrene Complexes : A New Type of Stabilized Artificial Chemical Nuclease ', Chemistry: A European Journal, vol. 25, no. 1, pp. 221-237 . https://doi.org/10.1002/chem.201804084مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Phenazine, Intercalation (chemistry), Molecular Conformation, DNA repair, chemistry.chemical_element, Biocompatible Materials, chemical nuclease, Crystallography, X-Ray, 010402 general chemistry, 01 natural sciences, Catalysis, Catalysi, chemistry.chemical_compound, Coordination Complexes, Phenanthrene, DNA CLEAVAGE ACTIVITY, COLI ENDONUCLEASE-III, DIRECT STRAND BREAKS, DEOXYINOSINE 3-ENDONUCLEASE, SUBSTRATE-SPECIFICITY, ELECTRONIC-STRUCTURE, BETA-ELIMINATION, MEDIATED DNA, CLIP-PHEN, PULSE-EPR, Endonuclease, Biocompatible Material, Nuclease, Coordination Complexe, biology, 010405 organic chemistry, phenazine, DNA Repair Enzyme, Organic Chemistry, Electron Spin Resonance Spectroscopy, Bioinorganic chemistry, DNA, General Chemistry, Nuclear magnetic resonance spectroscopy, Phenanthrenes, Endonucleases, Combinatorial chemistry, Copper, 0104 chemical sciences, DNA Repair Enzymes, chemistry, DNA glycosylase, copper, biology.protein, DNA damage, Amine gas treating
وصف الملف: ELETTRONICO
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المؤلفون: Teresa Lauria, Samuele Stazzoni, Andrew Kellett, Markus Müller, Vickie McKee, Antony Crisp, Creina Slator, Thomas Carell
المصدر: Lauria, T, Slator, C, McKee, V, Müller, M, Stazzoni, S, Crisp, A L, Carell, T & Kellett, A 2020, ' A Click Chemistry Approach to Developing Molecularly Targeted DNA Scissors ', Chemistry-A European Journal, vol. 26, no. 70, pp. 16782-16792 . https://doi.org/10.1002/chem.202002860
مصطلحات موضوعية: DNA damage, Oligonucleotides, chemistry.chemical_element, chemical nuclease, 010402 general chemistry, Ligands, 01 natural sciences, Catalysis, Turn (biochemistry), chemistry.chemical_compound, DNA triplexes, 010405 organic chemistry, Ligand, Oligonucleotide, Organic Chemistry, General Chemistry, DNA, Combinatorial chemistry, Copper, 0104 chemical sciences, chemistry, copper, click chemistry, Gene Targeting, Click chemistry, Nucleic acid, Nucleic Acid Conformation, Click Chemistry, Oxidation-Reduction, DNA Damage
وصف الملف: application/pdf
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المؤلفون: Vickie McKee, Andrew Kellett, Creina Slator, Zara Molphy
المصدر: Redox Biology
Redox Biology, Vol 12, Iss, Pp 150-161 (2017)مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, SKOV3, human ovarian carcinoma, Apoptosis, DSB, double strand breaks, Mitochondrion, Hydroxamic Acids, Biochemistry, Neoplasms, caspase, cysteine-dependent asparate-specific proteases CAT, catalase, Inner mitochondrial membrane, lcsh:QH301-705.5, Cancer, chemistry.chemical_classification, lcsh:R5-920, Vorinostat, Molecular Structure, Circular Dichroism, Histone deacetylase inhibitor, Superoxide, γH2AX, phosphorylated H2AX histone, 3. Good health, Cell biology, Mitochondria, SAHA, suberoylanilide hydroxamic acid, Rapa, rapamycin, lcsh:Medicine (General), Intracellular, Research Paper, topo, topoisomerase, Programmed cell death, DNA damage, medicine.drug_class, Cell Survival, Antineoplastic Agents, Biology, 03 medical and health sciences, ROS, reactive oxygen species, Dox, doxorubicin, SOD, superoxide dismutase, Cell Line, Tumor, CCCP, carbonyl cyanide m-chlorophenyl hydrazine, medicine, Autophagy, Organometallic Compounds, Humans, SSB, single strand breaks, Reactive oxygen species, Manganese, Organic Chemistry, Autophagosomes, MDC, monodansylcadarevine, 030104 developmental biology, chemistry, lcsh:Biology (General), Doxorubicin, LC-3, microtubule associated protein 1 light weight chain 3, Drug Screening Assays, Antitumor, Reactive Oxygen Species
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المؤلفون: Zara Molphy, Vickie McKee, Andrew Kellett, Creina Slator
المساهمون: Vessieres, Anne, Meier-Menches, Samuel M., Casini, Angela
المصدر: Metal-based Anticancer Agents ISBN: 9781788014069
Kellett, A, Molphy, Z, McKee, V & Slator, C 2019, Recent Advances in Anticancer Copper Compounds . in A Vessieres, S M Meier-Menches & A Casini (eds), Metal-based Anticancer Agents . Royal Society of Chemistry, RSC Metallobiology, no. 14, vol. 2019-January, pp. 91-119 . https://doi.org/10.1039/9781788016452-00091مصطلحات موضوعية: Cisplatin, chemistry.chemical_classification, Reactive oxygen species, Programmed cell death, chemistry.chemical_compound, Enzyme, chemistry, Biochemistry, medicine, Developmental Therapeutics Program, DNA, Reactive nitrogen species, Function (biology), medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c739c666407617cb1a694eeb062634
https://doi.org/10.1039/9781788016452-00091 -
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المؤلفون: Creina Slator, Vickie McKee, Zara Molphy, Nicholas Farrell, Andrew Kellett
المصدر: Kellett, A, Molphy, Z, Slator, C, McKee, V & Farrell, N P 2019, ' Molecular methods for assessment of non-covalent metallodrug-DNA interactions ', Chemical Society Reviews, vol. 48, no. 4, pp. 971-988 . https://doi.org/10.1039/c8cs00157j
Chemical Society Reviewsمصطلحات موضوعية: Models, Molecular, Circular dichroism, 02 engineering and technology, Computational biology, 010402 general chemistry, 01 natural sciences, Phosphates, chemistry.chemical_compound, Coordination Complexes, Phosphates/chemistry, Molecule, Humans, DNA/chemistry, Platinum, Molecular Structure, Drug discovery, Chemistry, General Chemistry, Nuclear magnetic resonance spectroscopy, DNA, Platinum/chemistry, 021001 nanoscience & nanotechnology, Coordination Complexes/chemistry, Small molecule, Intercalating Agents, 3. Good health, 0104 chemical sciences, Direct methods, Drug Design, Nucleic acid, Intercalating Agents/chemistry, Copper/chemistry, 0210 nano-technology, Copper
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052dd91c5dc562ea204e59db53833f8c
https://findresearcher.sdu.dk:8443/ws/files/153582434/c8cs00157j.pdf -
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المؤلفون: Georgia Menounou, Nicoló Zuin Fantoni, Andrew Kellett, Creina Slator, George Mitrikas, Vickie McKee, Chryssostomos Chatgilialoglu, Zara Molphy, Gianluca Toniolo
المصدر: Chemistry – A European Journal. 25
مصطلحات موضوعية: Nuclease, biology, Chemistry, DNA repair, DNA damage, Organic Chemistry, Phenazine, chemistry.chemical_element, General Chemistry, Phenanthrene, Copper, Catalysis, chemistry.chemical_compound, Polymer chemistry, biology.protein
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المؤلفون: Orla Howe, Andrew Kellett, Niall Barron, Creina Slator
المصدر: ACS Chemical Biology. 11:159-171
مصطلحات موضوعية: 0301 basic medicine, DNA damage, Antineoplastic Agents, Apoptosis, Mitochondrion, Biochemistry, 03 medical and health sciences, Cell Line, Tumor, medicine, Humans, Doxorubicin, Developmental Therapeutics Program, Mode of action, chemistry.chemical_classification, Reactive oxygen species, Microscopy, Confocal, Molecular Structure, biology, Topoisomerase, Cancer, General Medicine, medicine.disease, Molecular biology, Mitochondria, 030104 developmental biology, chemistry, biology.protein, Molecular Medicine, Reactive Oxygen Species, DNA Damage, Phenanthrolines, medicine.drug
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المؤلفون: Conor Long, Satish S. Bhat, Diego Montagner, Zara Molphy, Andrea Erxleben, Andrew Kellett, Creina Slator
المساهمون: Science Foundation Ireland, H2020 Marie Skłodowska-Curie Actions, European Regional Development Fund
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Free Radicals, DNA damage, Stereochemistry, Radical, Molecular Dynamics Simulation, Biology, 010402 general chemistry, 01 natural sciences, Molecular mechanics, Phosphates, Adduct, chemistry.chemical_compound, Chemical Biology and Nucleic Acid Chemistry, Organometallic Compounds, Genetics, DNA Cleavage, Groove binding, 010405 organic chemistry, Superoxide, Rational design, DNA, Phosphate-targeted dinuclear Cu(II) complex, Binding constant, 0104 chemical sciences, Oxidative Stress, chemistry, Nucleic Acid Conformation, Oxidative DNA cleavage, Oxidation-Reduction, Copper
وصف الملف: application/pdf; text
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7daf699f27ebae541a698f4ed2435714
http://hdl.handle.net/10379/14820 -
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المؤلفون: Tadhg J P McGivern, Celine J. Marmion, Andrew Kellett, Creina Slator
المصدر: Molecular pharmaceutics. 15(11)
مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, DNA damage, Cell Survival, Deoxyribozyme, Pharmaceutical Science, Antineoplastic Agents, Apoptosis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Drug Discovery, medicine, Organometallic Compounds, Humans, Prodrugs, Cell Proliferation, Vorinostat, DNA synthesis, Histone deacetylase inhibitor, DNA, Phenanthrenes, Intercalating Agents, 3. Good health, Histone Deacetylase Inhibitors, Oxidative Stress, 030104 developmental biology, Biochemistry, chemistry, 030220 oncology & carcinogenesis, Nucleic acid, Molecular Medicine, Histone deacetylase, Copper, Nucleotide excision repair, DNA Damage
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