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1دورية أكاديمية
المؤلفون: Nadia M J Rupniak, Elisabetta Perdona, Cristiana Griffante, Palmina Cavallini, Anna Sava, Daniel J Ricca, Karl B Thor, Edward C Burgard, Mauro Corsi
المصدر: PLoS ONE, Vol 13, Iss 10, p e0205894 (2018)
وصف الملف: electronic resource
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المؤلفون: Peng Gao, Paolo Vincetti, Fabio Maria Sabbatini, Holly J. Carlisle, Luisa Mengatto, Stéphane De Lombaert, Anna Sava, Kerry Zobel, Xinying Liu, Claudia Beato, Jessica M. Bright, Alyssa M. A. Toda, Elena Serra, Federica Budassi, Marco Migliore, Laura Caberlotto, Cristiana Griffante, Silvia Bernardi, Mingliang Zhang, Albert W. Garofalo, Daniele Andreotti
المصدر: Journal of Medicinal Chemistry. 63:14821-14839
مصطلحات موضوعية: Indazoles, Tetrazoles, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, 01 natural sciences, Small Molecule Libraries, Mice, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, Animals, Humans, Kinase activity, Protein Kinase Inhibitors, Gene, 030304 developmental biology, 0303 health sciences, Molecular Structure, Chemistry, Kinase, Highly selective, LRRK2, High-Throughput Screening Assays, nervous system diseases, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, HEK293 Cells, Pyrimidines, Mutation, Cancer research, Molecular Medicine
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المؤلفون: Cristiana Griffante, Rosaria Remelli, Ronaldo Silva, Francesco Rossignolo, Melissa Perfranceschi, Salvatore Scarso, Michela Padovani, Elisa Bianchini, Chiara Piubelli, Chiara Cazzin, Fabio Formenti, Francesca Perandin, Martina Leonardi
مصطلحات موضوعية: Alternative methods, Real-time polymerase chain reaction, Coronavirus disease 2019 (COVID-19), allergology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), RNA extraction, Biology, Virology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11d49255b046f0b8cd5f20eefc800c0
https://doi.org/10.20944/preprints202105.0342.v1 -
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المؤلفون: Nadia M.J. Rupniak, Cristiana Griffante, Mauro Corsi, Palmina Cavallini, Karl B. Thor, Anna Sava, Elisabetta Perdona, Daniel J. Ricca
المصدر: Neurosci Lett
مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.drug_class, chemistry.chemical_element, CHO Cells, Calcium, Article, law.invention, 03 medical and health sciences, 0302 clinical medicine, Cricetulus, law, medicine, Potency, Animals, Humans, Receptor, AMP synthesis, General Neuroscience, Receptors, Neurokinin-2, Receptors, Neurokinin-1, Recombinant Proteins, 030104 developmental biology, chemistry, Biochemistry, Cell culture, Recombinant DNA, Selectivity, 030217 neurology & neurosurgery
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المؤلفون: Anna Sava, Palmina Cavallini, Daniel J. Ricca, Nadia M.J. Rupniak, Mauro Corsi, Elisabetta Perdona, Edward C. Burgard, Karl B. Thor, Cristiana Griffante
المصدر: PLoS ONE, Vol 13, Iss 10, p e0205894 (2018)
PLoS ONEمصطلحات موضوعية: Neurokinin A, Drug Evaluation, Preclinical, Receptor agonist activity, lcsh:Medicine, Stimulation, Peptide, Biochemistry, Intracellular Receptors, chemistry.chemical_compound, Binding Analysis, 0302 clinical medicine, Cell Signaling, Cricetinae, Cyclic AMP, Membrane Receptor Signaling, Receptor, lcsh:Science, chemistry.chemical_classification, Multidisciplinary, integumentary system, Chemistry, Chinese hamster ovary cell, hemic and immune systems, Receptors, Neurokinin-2, Receptors, Neurokinin-1, respiratory system, Recombinant Proteins, Enzymes, Optical Equipment, 030220 oncology & carcinogenesis, Cell lines, Engineering and Technology, Biological cultures, Oxidoreductases, Luciferase, Research Article, Signal Transduction, Cell Binding, Cell Physiology, Equipment, CHO Cells, Research and Analysis Methods, 03 medical and health sciences, Cricetulus, Potency, Animals, Humans, Receptor Binding Assays, Chemical Characterization, EC50, Dose-Response Relationship, Drug, Cell Membrane, lcsh:R, Biology and Life Sciences, Proteins, Reproducibility of Results, Prisms, Cell Biology, Molecular biology, Enzymology, Calcium, lcsh:Q, Peptides, 030217 neurology & neurosurgery
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المؤلفون: Alessandro Poffe, Simone Spada, Carla Marchioro, Mauro Corsi, Romano Di Fabio, Michael Trower, Philip Gerrard, Giuseppe Alvaro, Simone Braggio, Cristiana Griffante, Laura Piccoli, Elvira Tranquillini, Sergio Melotto, Alfonso Pozzan, Emiliangelo Ratti, Renzo Carletti
المصدر: Bioorganic & Medicinal Chemistry. 21:6264-6273
مصطلحات موضوعية: Male, Models, Molecular, Orvepitant, Clinical Biochemistry, Molecular Conformation, Druggability, Pharmaceutical Science, CHO Cells, Pharmacology, Biology, Biochemistry, Piperazines, Cricetulus, Dogs, Neurokinin-1 Receptor Antagonists, Piperidines, Cricetinae, Drug Discovery, Casopitant, medicine, Animals, Humans, Receptor, Molecular Biology, Aprepitant, G protein-coupled receptor, Behavior, Animal, Organic Chemistry, Receptors, Neurokinin-1, Bridged Bicyclo Compounds, Heterocyclic, Antidepressive Agents, Rats, Molecular Medicine, Female, NK1 receptor antagonist, Pharmacophore, Gerbillinae, Half-Life, Protein Binding, medicine.drug
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المؤلفون: Elisabetta Perdona, Roberto Arban, Cristiana Griffante
المصدر: European Journal of Pharmacology. 679:16-23
مصطلحات موضوعية: Receptors, Vasopressin, endocrine system, medicine.medical_specialty, Vasopressin, Indoles, Pyrrolidines, Time Factors, Vasotocin, Adrenocorticotropic hormone, Oxytocin, Rats, Sprague-Dawley, chemistry.chemical_compound, Adrenocorticotropic Hormone, Pituitary Gland, Anterior, Internal medicine, Arginine vasopressin receptor 2, Cyclic AMP, medicine, Animals, Drug Interactions, Receptor, Cells, Cultured, Pharmacology, Arginine vasopressin receptor 1B, Chemistry, Oxytocin receptor, Rats, Arginine Vasopressin, Endocrinology, Calcium, Female, Antidiuretic Hormone Receptor Antagonists, hormones, hormone substitutes, and hormone antagonists, medicine.drug
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المؤلفون: Romano Di Fabio, Emiliangelo Ratti, Sergio Melotto, Mauro Corsi, Laura Zonzini, Giuseppe Alvaro, Daniele Donati, Cristiana Griffante, Domenica Antonia Pizzi, Zadeo Cimarosti, Stefano Provera, Philip Gerrard, David G. Trist, Giuseppe Guercio, Carla Marchioro, Dino Montanari, Mario Mattioli
المصدر: Journal of Medicinal Chemistry. 54:1071-1079
مصطلحات موضوعية: Drug discovery, Chemistry, medicine.drug_class, Carboxamide, Pharmacology, Vestipitant, In vivo, Drug Discovery, Casopitant, medicine, Molecular Medicine, NK1 receptor antagonist, Receptor, Aprepitant, medicine.drug
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المؤلفون: Laura Zonzini, Giuseppe Alvaro, Stefano Provera, Giorgio Pentassuglia, Daniele Donati, Cristiana Griffante, Zadeo Cimarosti, Giuseppe Guercio, Carla Marchioro, Romano Di Fabio, Mario Mattioli, David G. Trist, Dino Montanari, Mauro Corsi, Philip Gerrard, Domenica Antonia Pizzi, Emiliangelo Ratti, Tino Rossi, Sergio Melotto
المصدر: Journal of Medicinal Chemistry. 52:3238-3247
مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, Carboxylic acid, Antagonist, Methylamide, Vestipitant, Piperazine, chemistry.chemical_compound, chemistry, Pharmacokinetics, In vivo, Drug Discovery, Molecular Medicine, NK1 receptor antagonist
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المؤلفون: Cristiana Griffante, Sharla F. Young, Greti Aguilera
المصدر: Cellular and Molecular Neurobiology. 27:439-461
مصطلحات موضوعية: Receptors, Vasopressin, Corticotropin-Releasing Hormone, Vasopressins, Recombinant Fusion Proteins, Corticotropin-releasing hormone receptor, CHO Cells, Biology, Transfection, Receptors, Corticotropin-Releasing Hormone, Cellular and Molecular Neuroscience, Corticotropin-releasing hormone, Cricetulus, Thyrotropin-releasing hormone receptor, Cricetinae, Enzyme-linked receptor, Animals, Humans, Receptor, G protein-coupled receptor, Arginine vasopressin receptor 1B, Cell Biology, General Medicine, Ligand (biochemistry), Cell biology, Biochemistry, Dimerization, Protein Binding