المؤلفون: Yoshitsugu Aoki, Cristina S. J. Rocha, Taavi Lehto, Shouta Miyatake, Henrik Johansson, Yasumasa Hashimoto, Joel Z. Nordin, Imre Mager, Misako Aoki, McClorey Graham, Chaitra Sathyaprakash, Thomas C. Roberts, Matthew J. A. Wood, Mark A. Behlke, Samir El Andaloussi

المصدر: Frontiers in Physiology, Vol 12 (2021)

مصطلحات موضوعية: skeletal muscle, Duchenne muscular dystrophy, splice-switching oligonucleotide (SSO), phosphorothioate, 2OMePS, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2021.689179/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/0ea4440e5f7542ee82645e95690437a3

المؤلفون: Catarina Nilsson, Rosanne M. Crooke, Nigel Davies, Birgitta Rosengren, Brett P. Monia, Eva Hurt-Camejo, Cristina S. J. Rocha, Tina Rydén-Bergsten, Stan Riney, Daniel Lindén, Rosie Z. Yu, Yanfeng Wang, Peter Gennemark, Anna Tivesten, Dorota Kakol-Palm, Ulf Andersson, Lloyd G. Tillman, Marie Elebring, Björn Carlsson, Mikko Hölttä, Jane Knöchel, Linda Wernevik, Rasmus Jansson-Löfmark, Niclas Clemmensen, Rikard Isaksson, Katrin Walter, Richard S. Geary, Dinko Rekić

المصدر: Science Translational Medicine. 13

مصطلحات موضوعية: 0301 basic medicine, 030204 cardiovascular system & hematology, Pharmacology, 03 medical and health sciences, Subcutaneous injection, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Oral administration, medicine, Animals, Potency, business.industry, Cholesterol, PCSK9, PCSK9 Inhibitors, Serine Endopeptidases, General Medicine, Oligonucleotides, Antisense, medicine.disease, Rats, Bioavailability, Macaca fascicularis, 030104 developmental biology, chemistry, business, Dyslipidemia, Lipoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197948bccc867454748627a58e0b6234
https://doi.org/10.1126/scitranslmed.abe9117

المؤلفون: Yanfeng Wang, Anna Tivesten, Niclas Clemmensen, Dinko Rekić, Mikko Hölttä, Marie Elebring, Lloyd G. Tillman, Catarina Nilsson, Björn Carlsson, stanley riney, Rosie Z. Yu, Kristina Ryden-Bergsten, Brett P. Monia, Rosanne M. Crooke, Daniel Lindén, Jane Knoechel, Katrin Walter, Eva Hurt-Camejo, Rasmus Jansson-Löfmark, Cristina S. J. Rocha, Peter Gennemark, Ulf Andersson, Nigel Davies

المصدر: Circulation. 142

مصطلحات موضوعية: business.industry, PCSK9, Arteriosclerosis, 030204 cardiovascular system & hematology, Pharmacology, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Antisense oligonucleotides, Medicine, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, business, PCSK9 Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9933060a0f89627c4a1483b9e72cb980
https://doi.org/10.1161/circ.142.suppl_3.13307

المؤلفون: Cristina S J, Rocha

المصدر: Methods in molecular biology (Clifton, N.J.). 2036

مصطلحات موضوعية: Gene Expression Regulation, RNA Splicing, Humans, RNA, Messenger, Oligonucleotides, Antisense, Proprotein Convertase 9, Cell Line

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::47a57602903766b6282d3f9ea98ad5d3
https://pubmed.ncbi.nlm.nih.gov/31410791

المؤلفون: Cristina S. J. Rocha

المصدر: Methods in Molecular Biology ISBN: 9781493996698

مصطلحات موضوعية: chemistry.chemical_classification, Drug, 0303 health sciences, Computer science, Oligonucleotide, Biomolecule, media_common.quotation_subject, RNA, Computational biology, Small molecule, 03 medical and health sciences, 0302 clinical medicine, Real-time polymerase chain reaction, Drug development, chemistry, 030220 oncology & carcinogenesis, Gene expression, Potency, splice, RNA extraction, Mode of action, 030304 developmental biology, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::da2810f23f888e7f7517baba74de9539
https://doi.org/10.1007/978-1-4939-9670-4_4

المؤلفون: Cristina S. J. Rocha, Oscar P. B. Wiklander, Pedro Moreno, C. I. Edvard Smith, Lilian Larsson, Karin E. Lundin, Paolo Parini

المصدر: Journal of Molecular and Cellular Cardiology. 82:186-193

مصطلحات موضوعية: Small interfering RNA, Cell Survival, RNA Splicing, Hypercholesterolemia, Intracellular Space, Oligonucleotides, Gene Expression, Familial hypercholesterolemia, 030204 cardiovascular system & hematology, Biology, Transfection, Cell Line, PCSK9, Mice, 03 medical and health sciences, Gene therapy, 0302 clinical medicine, Genes, Reporter, medicine, Animals, Humans, splice, Gene Silencing, Molecular Biology, 030304 developmental biology, 0303 health sciences, Serine Endopeptidases, RNA therapeutics, RNA, medicine.disease, Proprotein convertase, 3. Good health, Protein Transport, Receptors, LDL, Biochemistry, LDL receptor, Hepatocytes, Kexin, lipids (amino acids, peptides, and proteins), Proprotein Convertases, Proprotein Convertase 9, Splice modulation, Cardiology and Cardiovascular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90796cb84e46de90530f175400d55deb

المؤلفون: Cristina S. J. Rocha, Stefan Milton, Dmytro Honcharenko, Roger Strömberg, Pedro Moreno, C. I. Edvard Smith

المصدر: Chemical Communications. 51:4044-4047

مصطلحات موضوعية: Nuclease, biology, Chemistry, Oligonucleotide, Cell, Esterases, Oligonucleotides, Metals and Alloys, Biological Transport, General Chemistry, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, High resistance, medicine.anatomical_structure, Biochemistry, Cell Line, Tumor, Materials Chemistry, Ceramics and Composites, biology.protein, medicine, Humans, Enzymatic degradation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db661339ebec70f2360e3e9a7e799f1a
https://doi.org/10.1039/c4cc08837a

المؤلفون: Y. Vladimir Pabon, Burcu Bestas, Sylvain Geny, Samir El Andaloussi, Rula Zain, C. I. Edvard Smith, Per T. Jørgensen, Jesper Wengel, Eman M. Zaghloul, Cristina S. J. Rocha, Helen Bergquist, Iulian I. Oprea, Erik B. Pedersen, Pedro Moreno, Karin E. Lundin

المصدر: Moreno, P M D, Geny, S, Pabon, Y V, Bergquist, H, Zaghloul, E M, Rocha, C S J, Oprea, I I, Bestas, B, Andaloussi, S E, Jørgensen, P T, Pedersen, E B, Lundin, K E, Zain, R, Wengel, J & Smith, C I E 2013, ' Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA ', Nucleic Acids Research, vol. 41, no. 5, pp. 3257-3273 . https://doi.org/10.1093/nar/gkt007
Nucleic Acids Research
Nucleic Acids Research; Vol 41

مصطلحات موضوعية: Base pair, Molecular Sequence Data, Oligonucleotides, Context (language use), Buffers, Biology, 010402 general chemistry, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Plasmid, Genetics, Transition Temperature, Strand invasion, DNA Cleavage, Locked nucleic acid, Base Pairing, Molecular Biology, 030304 developmental biology, 0303 health sciences, Binding Sites, Base Sequence, DNA, Superhelical, Oligonucleotide, DNA, DNA Restriction Enzymes, Hydrogen-Ion Concentration, 0104 chemical sciences, Biochemistry, chemistry, Nucleic acid, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33c536d31a11df21278a74d1e527aa4
https://doi.org/10.1093/nar/gkt007

المؤلفون: Mark W. Rutland, Helen Bergquist, Cristina S. J. Rocha, C. I. Edvard Smith, Peter E. Nielsen, Chi-Hung Nguyen, Rubén Álvarez-Asencio, Liam Good, Rula Zain

المصدر: PLoS One
Bergquist, H, Rocha, C S J, Alvarez-Asencio, R, Chi-Hung Nguyen, Rutland, M W, Smith, C I E, Good, L, Nielsen, P E & Zain, R 2016, ' Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)(n) Repeats by PNA or LNA Targeting ', P L o S One, vol. 11, no. 11, e0165788 . https://doi.org/10.1371/journal.pone.0165788
Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
instname
PLoS ONE, Vol 11, Iss 11, p e0165788 (2016)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Peptide Nucleic Acids, Molecular biology, Oligonucleotides, lcsh:Medicine, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Plasmid, lcsh:Science, DNA cleavage, Microscopy, Multidisciplinary, Peptide nucleic acid, Nucleotides, Organic Compounds, Biochemistry and Molecular Biology, Genomics, Atomic Force Microscopy, Nucleic acids, Chemistry, Physical Sciences, Sequence Analysis, Research Article, congenital, hereditary, and neonatal diseases and abnormalities, Materials by Structure, Materials Science, Biology, 010402 general chemistry, Research and Analysis Methods, 03 medical and health sciences, Sequence Motif Analysis, Genetics, Humans, Repeated Sequences, Locked nucleic acid, Nucleotide Motifs, Molecular Biology Techniques, Sequencing Techniques, Gene, Base Sequence, Biology and life sciences, Oligonucleotide, Scanning Probe Microscopy, Organic Chemistry, lcsh:R, Intron, Chemical Compounds, DNA structure, nutritional and metabolic diseases, DNA, 0104 chemical sciences, Macromolecular structure analysis, 030104 developmental biology, Pyrimidines, chemistry, Friedreich Ataxia, Oligomers, Frataxin, biology.protein, Nucleic Acid Conformation, lcsh:Q, Trinucleotide Repeat Expansion, Biokemi och molekylärbiologi

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116779149fe0c756b689293ed9276dbb
http://hdl.handle.net/20.500.12614/379

المؤلفون: Oscar P. B. Wiklander, Kariem Ezzat, Jean-Louis Reymond, Florian Hollfelder, Dhanu Gupta, C. I. Edvard Smith, Rula Zain, Osama Saher, Eman M. Zaghloul, Cristina S. J. Rocha, Marc Heitz, Karin E. Lundin, Samir El Andaloussi, Susanna Zamolo, Tamis Darbre

المصدر: European Journal of Pharmaceutics and Biopharmaceutics

مصطلحات موضوعية: Dendrimers, Genetic enhancement, Genetic Vectors, Oligonucleotides, Pharmaceutical Science, Peptide, 02 engineering and technology, Transfection, 010402 general chemistry, 01 natural sciences, Cell Line, Mice, Genes, Reporter, Dendrimer, 540 Chemistry, Animals, Humans, Tissue Distribution, Particle Size, Cytotoxicity, chemistry.chemical_classification, Oligonucleotide, Gene Transfer Techniques, Genetic Therapy, General Medicine, 021001 nanoscience & nanotechnology, Lipids, 0104 chemical sciences, chemistry, Cell culture, Biophysics, 570 Life sciences, biology, Female, Peptides, 0210 nano-technology, Ternary operation, HeLa Cells, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec1fed14190a4ba0f137b1c39d1b8c4