المؤلفون: Mannion J; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Gifford V; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Bellenie B; Centre for Cancer Drug Discovery at the Institute of Cancer Research, London SM2 5NG, UK., Fernando W; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Ramos Garcia L; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Wilson R; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., John SW; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Udainiya S; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Patin EC; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London SW3 6JB, UK., Tiu C; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Smith A; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Goicoechea M; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Craxton A; MRC Toxicology Unit, University of Cambridge, Gleeson Building, Cambridge CB2 1QR, UK., Moraes de Vasconcelos N; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Guppy N; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Cheung KJ; Centre for Cancer Drug Discovery at the Institute of Cancer Research, London SM2 5NG, UK., Cundy NJ; Centre for Cancer Drug Discovery at the Institute of Cancer Research, London SM2 5NG, UK., Pierrat O; Centre for Cancer Drug Discovery at the Institute of Cancer Research, London SM2 5NG, UK., Brennan A; Centre for Cancer Drug Discovery at the Institute of Cancer Research, London SM2 5NG, UK., Roumeliotis TI; Functional Proteomics Group, The Institute of Cancer Research, London SW3 6JB, UK., Benstead-Hume G; Functional Proteomics Group, The Institute of Cancer Research, London SW3 6JB, UK., Alexander J; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Muirhead G; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Layzell S; Institute of Immunity and Transplantation, University College London, London NW3 2PP, UK., Lyu W; Department of Immunology and Microbiology, LEO Foundation Skin Immunology Research Center, University of Copenhagen, Copenhagen, Denmark., Roulstone V; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London SW3 6JB, UK., Allen M; Biological Services Unit, The Institute of Cancer Research, London SW3 6JB, UK., Baldock H; Biological Services Unit, The Institute of Cancer Research, London SW3 6JB, UK., Legrand A; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Gabel F; Centre for Cancer Drug Discovery at the Institute of Cancer Research, London SM2 5NG, UK., Serrano-Aparicio N; Centre for Cancer Drug Discovery at the Institute of Cancer Research, London SM2 5NG, UK., Starling C; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Guo H; Department of Microbiology and Immunology, LSU Health Shreveport, Shreveport, LA, USA., Upton J; Department of Biological Sciences, Auburn University, Auburn, AL, USA., Gyrd-Hansen M; Department of Immunology and Microbiology, LEO Foundation Skin Immunology Research Center, University of Copenhagen, Copenhagen, Denmark., MacFarlane M; MRC Toxicology Unit, University of Cambridge, Gleeson Building, Cambridge CB2 1QR, UK., Seddon B; Institute of Immunity and Transplantation, University College London, London NW3 2PP, UK., Raynaud F; Centre for Cancer Drug Discovery at the Institute of Cancer Research, London SM2 5NG, UK., Roxanis I; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Harrington K; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London SW3 6JB, UK., Haider S; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK., Choudhary JS; Functional Proteomics Group, The Institute of Cancer Research, London SW3 6JB, UK., Hoelder S; Centre for Cancer Drug Discovery at the Institute of Cancer Research, London SM2 5NG, UK., Tenev T; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK. Electronic address: tencho.tenev@icr.ac.uk., Meier P; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK. Electronic address: pmeier@icr.ac.uk.

المصدر: Immunity [Immunity] 2024 Jul 09; Vol. 57 (7), pp. 1514-1532.e15. Date of Electronic Publication: 2024 May 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

مواضيع طبية MeSH: Receptor-Interacting Protein Serine-Threonine Kinases*/metabolism , Proteolysis*/drug effects , Signal Transduction*/drug effects , Immunogenic Cell Death*/drug effects, Humans ; Animals ; Mice ; Cell Line, Tumor ; Necroptosis/drug effects ; Necroptosis/immunology ; Neoplasms/immunology ; Neoplasms/drug therapy ; Mice, Inbred C57BL ; Antineoplastic Agents/pharmacology ; Immunotherapy/methods

المؤلفون: Cui Y; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Lanne A; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Peng X; State Key Laboratory of Respiratory Disease, China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, 190 Kai Yuan Avenue, Science Park, Guangzhou 510530, China., Browne E; Sygnature Discovery, The Discovery Building, BioCity, Pennyfoot Street, Nottingham NG1 1GR, U.K., Bhatt A; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Coltman NJ; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Craven P; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Cox LR; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Cundy NJ; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Dale K; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Feula A; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Frampton J; College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Fung M; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, 15 Science Park West Avenue NT, Hong Kong SAR., Morton M; ApconiX Ltd, BIOHUB at Alderly Park, Nether Alderly, Cheshire SK10 4TG, U.K., Goff A; Department of Global Health and Infection, Brighton and Sussex Medical School, University of Sussex, Falmer BN1 9PX, U.K., Salih M; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Lang X; State Key Laboratory of Respiratory Disease, China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, 190 Kai Yuan Avenue, Science Park, Guangzhou 510530, China., Li X; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K.; State Key Laboratory of Respiratory Disease, China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, 190 Kai Yuan Avenue, Science Park, Guangzhou 510530, China., Moon C; TB Research Group, National Infection Service, Public Health England (UKHSA), Manor Farm Road, Porton, Salisbury SP4 0JG, U.K., Pascoe J; TB Research Group, National Infection Service, Public Health England (UKHSA), Manor Farm Road, Porton, Salisbury SP4 0JG, U.K., Portman V; Sygnature Discovery, The Discovery Building, BioCity, Pennyfoot Street, Nottingham NG1 1GR, U.K., Press C; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Schulz-Utermoehl T; Sygnature Discovery, The Discovery Building, BioCity, Pennyfoot Street, Nottingham NG1 1GR, U.K., Lee S; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, 15 Science Park West Avenue NT, Hong Kong SAR., Tortorella MD; State Key Laboratory of Respiratory Disease, China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, 190 Kai Yuan Avenue, Science Park, Guangzhou 510530, China.; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, 15 Science Park West Avenue NT, Hong Kong SAR., Tu Z; State Key Laboratory of Respiratory Disease, China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, 190 Kai Yuan Avenue, Science Park, Guangzhou 510530, China., Underwood ZE; TB Research Group, National Infection Service, Public Health England (UKHSA), Manor Farm Road, Porton, Salisbury SP4 0JG, U.K., Wang C; State Key Laboratory of Respiratory Disease, China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, 190 Kai Yuan Avenue, Science Park, Guangzhou 510530, China., Yoshizawa A; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Zhang T; State Key Laboratory of Respiratory Disease, China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, 190 Kai Yuan Avenue, Science Park, Guangzhou 510530, China., Waddell SJ; Department of Global Health and Infection, Brighton and Sussex Medical School, University of Sussex, Falmer BN1 9PX, U.K., Bacon J; TB Research Group, National Infection Service, Public Health England (UKHSA), Manor Farm Road, Porton, Salisbury SP4 0JG, U.K., Alderwick L; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K.; Discovery Sciences, Charles River Laboratories, Chesterford Research Park, Saffron Walden CB10 1XL, U.K., Fossey JS; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K., Neagoie C; State Key Laboratory of Respiratory Disease, China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, 190 Kai Yuan Avenue, Science Park, Guangzhou 510530, China.; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, 15 Science Park West Avenue NT, Hong Kong SAR.; Visiting Scientist, School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Feb 22; Vol. 67 (4), pp. 2529-2548. Date of Electronic Publication: 2024 Feb 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Mycobacterium tuberculosis* , Azetidines*/pharmacology , Azetidines*/therapeutic use , Tuberculosis, Multidrug-Resistant*/drug therapy , Extensively Drug-Resistant Tuberculosis*/drug therapy, Humans ; Antitubercular Agents/pharmacology ; Antitubercular Agents/therapeutic use ; Microbial Sensitivity Tests

المؤلفون: Gates EWJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada., Calvert ND; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada., Cundy NJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada., Brugnoli F; Department of Translational Medicine, University of Ferrara, 44021 Ferrara, Italy., Navals P; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada., Kirby A; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada., Bianchi N; Department of Translational Medicine, University of Ferrara, 44021 Ferrara, Italy., Adhikary G; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Shuhendler AJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada., Eckert RL; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Keillor JW; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 08; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Protein Glutamine gamma Glutamyltransferase 2* , Neoplasms*, Humans ; Transglutaminases ; Fluorescent Dyes ; Phenotype

المؤلفون: Cundy NJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Arciszewski J; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Gates EWJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Acton SL; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Passley KD; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Awoonor-Williams E; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Boyd EK; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Xu N; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Pierson É; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Fernandez-Ansieta C; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Albert MR; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., McNeil NMR; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca., Adhikary G; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine Baltimore Maryland 21201 USA., Eckert RL; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine Baltimore Maryland 21201 USA., Keillor JW; Department of Chemistry and Biomolecular Sciences, University of Ottawa Ottawa Ontario K1N 6N5 Canada jkeillor@uottawa.ca.

المصدر: RSC medicinal chemistry [RSC Med Chem] 2022 Dec 28; Vol. 14 (2), pp. 378-385. Date of Electronic Publication: 2022 Dec 28 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem Subsets: PubMed not MEDLINE

المؤلفون: McNeil NMR; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Gates EWJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Firoozi N; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Cundy NJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Leccese J; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Eisinga S; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada., Tyndall JDA; School of Pharmacy, University of Otago, Dunedin, 9054, New Zealand., Adhikary G; Department of Biochemistry and Molecular Biology, and the Greenebaum Comprehensive Cancer Center, The University of Maryland School of Medicine, Baltimore, MD, 21021, USA., Eckert RL; Department of Biochemistry and Molecular Biology, and the Greenebaum Comprehensive Cancer Center, The University of Maryland School of Medicine, Baltimore, MD, 21021, USA., Keillor JW; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada. Electronic address: jkeillor@uottawa.ca.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2022 Mar 15; Vol. 232, pp. 114172. Date of Electronic Publication: 2022 Feb 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Peptidomimetics*/pharmacology , Transglutaminases*/chemistry , Transglutaminases*/genetics , Transglutaminases*/metabolism, Enzyme Inhibitors/chemistry ; Protein Glutamine gamma Glutamyltransferase 2 ; Structure-Activity Relationship

المؤلفون: Cundy NJ; School of Chemistry, University of Birmingham Edgbaston Birmingham B15 2TT UK r.s.grainger@bham.ac.uk., Hare RK; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester Manchester M13 9PL UK., Tang T; Celentyx Ltd, Birmingham Research Park 97 Vincent Drive Birmingham B15 2SQ UK., Leach AG; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, University of Manchester Manchester M13 9PL UK sam.butterworth@manchester.ac.uk., Jowitt TA; Wellcome Trust Centre for Cell Matrix Research, Faculty of Biology, Medicine and Health, University of Manchester Manchester M13 9PL UK., Qureshi O; Celentyx Ltd, Birmingham Research Park 97 Vincent Drive Birmingham B15 2SQ UK., Gordon J; Celentyx Ltd, Birmingham Research Park 97 Vincent Drive Birmingham B15 2SQ UK., Barnes NM; Celentyx Ltd, Birmingham Research Park 97 Vincent Drive Birmingham B15 2SQ UK.; Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham Edgbaston Birmingham B15 2TT UK., Brady CA; Celentyx Ltd, Birmingham Research Park 97 Vincent Drive Birmingham B15 2SQ UK.; Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham Edgbaston Birmingham B15 2TT UK., Raven EL; School of Chemistry, University of Bristol Cantock's Close Bristol BS8 1TS UK., Grainger RS; School of Chemistry, University of Birmingham Edgbaston Birmingham B15 2TT UK r.s.grainger@bham.ac.uk., Butterworth S; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, University of Manchester Manchester M13 9PL UK sam.butterworth@manchester.ac.uk.

المصدر: RSC chemical biology [RSC Chem Biol] 2021 Sep 13; Vol. 2 (6), pp. 1651-1660. Date of Electronic Publication: 2021 Sep 13 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101768727 Publication Model: eCollection Cited Medium: Internet ISSN: 2633-0679 (Electronic) Linking ISSN: 26330679 NLM ISO Abbreviation: RSC Chem Biol Subsets: PubMed not MEDLINE