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1كتاب
المساهمون: Kalinski, Michael I., 1943-
مصطلحات موضوعية: Second Messenger Systems -- physiology., Cyclic AMP-Dependent Protein Kinases -- metabolism., Cyclic AMP -- metabolism., Muscles -- metabolism., Exercise -- physiology., Muscles -- Physiology., Myocardium -- Physiology., Exercise -- Physiological aspects., Cyclic adenylic acid., Protein kinases., Phosphorylation.
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المؤلفون: Marta Gil-Ortega, Beatriz Somoza, María S. Fernández-Alfonso, Marta Viana, M. Paz Lorenzo, Martín Alcalá, Thomas Unger, Raquel González-Blázquez, William A. Boisvert, Ulrike Muscha Steckelings
المساهمون: Bedrijfsbureau CD, RS: CARIM other
المصدر: González-Blázquez, R, Alcalá, M, Fernández-Alfonso, M S, Steckelings, U M, Lorenzo, M P, Viana, M, Boisvert, W, Unger, T, Ortega, M G & Somoza, B 2021, ' C21 preserves endothelial function in the thoracic aorta from DIO mice : role for AT2, Mas and B2 receptors ', Clinical Science, vol. 135, no. 9, pp. 1145-1163 . https://doi.org/10.1042/CS20210049
Clinical Science, 135(9), 1145-1163. Portland Press Ltd.مصطلحات موضوعية: Male, Receptor, Bradykinin B2, Drug Evaluation, Preclinical, Aorta, Thoracic, Vasodilation, Inbred C57BL, Proto-Oncogene Mas, Receptors, G-Protein-Coupled, Renin-Angiotensin System, Mice, Angiotensin, chemistry.chemical_compound, Bradykinin B2/metabolism, Signal Transduction/drug effects, Receptors, Proto-Oncogene Proteins c-akt/metabolism, Thoracic aorta, Thoracic/drug effects, Endothelial dysfunction, Receptor, Aorta, Vascular/drug effects, Imidazoles/pharmacology, Sulfonamides, Imidazoles, General Medicine, Receptor, Angiotensin, Type 2/agonists, Preclinical, Aorta, Thoracic/drug effects, Signal transduction, Signal Transduction, Type 2/agonists, Agonist, Endothelium, Vascular/drug effects, medicine.medical_specialty, Nitric Oxide Synthase Type III, Sulfonamides/pharmacology, medicine.drug_class, Bradykinin, Thiophenes/pharmacology, Thiophenes, Diet, High-Fat, Nitric Oxide, Cyclic AMP-Dependent Protein Kinases/metabolism, Receptor, Angiotensin, Type 2, Proto-Oncogene Proteins, medicine.artery, Internal medicine, Human Umbilical Vein Endothelial Cells, medicine, Animals, Humans, Endothelium, Obesity, Vascular Diseases, Receptor, Bradykinin B2/metabolism, Protein kinase B, G-Protein-Coupled/metabolism, Vascular Diseases/etiology, Nitric Oxide Synthase Type III/metabolism, Receptor Cross-Talk, Receptors, G-Protein-Coupled/metabolism, Proto-Oncogene Proteins/metabolism, medicine.disease, Cyclic AMP-Dependent Protein Kinases, Diet, Mice, Inbred C57BL, High-Fat, Endocrinology, chemistry, Renin-Angiotensin System/drug effects, Nitric Oxide/metabolism, Drug Evaluation, Endothelium, Vascular, Obesity/complications, Proto-Oncogene Proteins c-akt
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877a98634f9c9ee846c5eeeae1f14062
https://portal.findresearcher.sdu.dk/da/publications/d3fcf2be-7770-4967-9d40-5384bb58c9fe -
3رسالة جامعية
المؤلفون: Dukuzumuremyi, Jean-Marie
مصطلحات موضوعية: Yersinia -- enzymology, Yersinia -- metabolism, Yersinia -- pathogenicity, Inflammation, Proteinkinases, Salmonella enterica -- genetics, Salmonella enterica -- metabolism, Bacterial proteins -- genetics, Bacterial proteins -- metabolism, rac GTP-binding protein -- metabolism, rhoA GTP-binding protein -- metabolism, Virulence, Cyclic AMP-dependent protein kinases -- metabolism, Cyclic AMP-dependent protein kinases -- physiology
Degree: Diss. (sammanfattning) Lund : Univ., 2003
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المؤلفون: Beatris Mastelic-Gavillet, Selena Vigano, Grégory Verdeil, Massimo Valerio, George Coukos, Haiping Wang, Rita Ahmed, Ping-Chih Ho, Laurent Derré, Nicolas Gestermann, Christine Ménétrier-Caux, Alexandre Harari, Camilla Jandus, Daniel E. Speiser, Blanca Navarro Rodrigo, Giuseppe Ercolano, Tu Nguyen-Ngoc, Patrice Jichlinski, Lana E. Kandalaft, Angela Ianaro, Leyder Elena Lozano, Pedro Romero, Christophe Caux, Thomas Tawadros, Olivier Dormond, Laure Décombaz
المساهمون: Mastelic-Gavillet, B., Navarro Rodrigo, B., Decombaz, L., Wang, H., Ercolano, G., Ahmed, R., Lozano, L. E., Ianaro, A., Derre, L., Valerio, M., Tawadros, T., Jichlinski, P., Nguyen-Ngoc, T., Speiser, D. E., Verdeil, G., Gestermann, N., Dormond, O., Kandalaft, L., Coukos, G., Jandus, C., Menetrier-Caux, C., Caux, C., Ho, P. -C., Romero, P., Harari, A., Vigano, S.
المصدر: Journal for Immunotherapy of Cancer, Vol. 7, No 1 (2019) P. 257
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Journal for Immunotherapy of Cancer
Journal for immunotherapy of cancer, vol. 7, no. 1, pp. 257مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Adenosine, medicine.medical_treatment, Lymphocyte, mTORC1, CD8-Positive T-Lymphocytes, 0302 clinical medicine, Neoplasms, Tumor Microenvironment, Immunology and Allergy, Cytotoxic T cell, Aged, 80 and over, Chemistry, Adenosine/immunology, Adenosine/metabolism, Adult, Aged, CD8-Positive T-Lymphocytes/immunology, CD8-Positive T-Lymphocytes/metabolism, Cell Line, Tumor, Cyclic AMP-Dependent Protein Kinases/metabolism, Disease Progression, Female, Humans, Lymphocytes, Tumor-Infiltrating/immunology, Lymphocytes, Tumor-Infiltrating/metabolism, Mechanistic Target of Rapamycin Complex 1/metabolism, Middle Aged, Neoplasms/immunology, Neoplasms/metabolism, Primary Cell Culture, Receptor, Adenosine A2A/metabolism, Signal Transduction/immunology, Tumor Escape, Tumor Microenvironment/immunology, CD8 T cells, Metabolism, TILs, mTOR, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, Cyclic AMP-Dependent Protein Kinase, Research Article, Human, Signal Transduction, Receptor, Adenosine A2A, T cell, Immunology, Mechanistic Target of Rapamycin Complex 1, lcsh:RC254-282, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, medicine, Pharmacology, Tumor microenvironment, Immunotherapy, TIL, CD8-Positive T-Lymphocyte, Cyclic AMP-Dependent Protein Kinases, T cell cytokine production, 030104 developmental biology, CD8 T cell, Cancer research, Neoplasm, CD8
وصف الملف: application/pdf
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5رسالة جامعية
المؤلفون: Cheng, Sam Xian Jun
مصطلحات موضوعية: Cyclic AMP-dependent protein kinases: metabolism
URL الوصول: http://diss.kib.ki.se/1998/91-628-2971-8
Degree: Diss. (sammanfattning) Stockholm : Karol. inst.
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المؤلفون: Jan Haas, Maarten M.G. van den Hoogenhof, Jens Mogensen, Torsten Bloch Rasmussen, Abdelaziz Beqqali, Hanneke W. M. van Deutekom, Ralph J. van Oort, Esther E. Creemers, Ilse A. E. Bollen, Benjamin Meder, Jolanda van der Velden, Sebastian Schafer, Keld E. Sørensen, Yigal M. Pinto, Norbert Hubner
المساهمون: ACS - Amsterdam Cardiovascular Sciences, Cardiology, Graduate School, Physiology, ICaR - Heartfailure and pulmonary arterial hypertension
المصدر: Cardiovascular research, 112(1), 452-463. Oxford University Press
Beqqali, A, Bollen, I A E, Rasmussen, T B, van den Hoogenhof, M M, van Deutekom, H W M, Schafer, S, Haas, J, Meder, B, Sorensen, K E, van Oort, R J, Mogensen, J, Hubner, N, Creemers, E E, van der Velden, J & Pinto, Y M 2016, ' A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank-Starling mechanism ', Cardiovascular Research, vol. 112, no. 1, pp. 452-463 . https://doi.org/10.1093/cvr/cvw192
Beqqali, A, Bollen, I A E, Rasmussen, T B, van den Hoogenhof, M M, van Deutekom, H W M, Schafer-Korting, M, Haas, J, Meder, B, Sorensen, K E, van Oort, R J, Mogensen, J, Hubner, N, Creemers, E E, van der Velden, J & Pinto, Y M 2016, ' A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank-Starling mechanism ', Cardiovascular Research, vol. 112, no. 1, pp. 452-463 . https://doi.org/10.1093/cvr/cvw192
Cardiovascular Research, 112(1), 452-463. Oxford University Pressمصطلحات موضوعية: Male, 0301 basic medicine, Heredity, Cardiomyopathy, Dilated/genetics, Physiology, DNA Mutational Analysis, Dilated cardiomyopathy, RNA-binding protein, Haploinsufficiency, Exon, Protein Isoforms, Connectin, Myocytes, Cardiac, Sarcomere Cardiomyopathy Dilated cardiomyopathy Heart failure Alternative splicing RBM20 length-dependent activation calcium homeostasis troponin-i rbm20 expression gene myocardium stiffness reveals tension Cardiovascular System & Cardiology, Phosphorylation, Genetics, RBM20, biology, Connectin/genetics, Models, Cardiovascular, RNA-Binding Proteins, Sarcomere, Myocytes, Cardiac/metabolism, Pedigree, Cell biology, Actinin, alpha 2, Phenotype, RNA splicing, Female, Titin, Cardiology and Cardiovascular Medicine, Muscle Contraction, Cardiomyopathy, Dilated, Adult, Heterozygote, Cardiomyopathy, Heart failure, Obscurin, Transfection, Cyclic AMP-Dependent Protein Kinases/metabolism, Cell Line, 03 medical and health sciences, Physiology (medical), Humans, Animals, Genetic Predisposition to Disease, Genetic Association Studies, Aged, Alternative splicing, Cyclic AMP-Dependent Protein Kinases, RNA-Binding Proteins/genetics, Rats, Alternative Splicing, 030104 developmental biology, Case-Control Studies, Mutation, biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0c488167b9fa7596e65c231f88d4a2
https://doi.org/10.1093/cvr/cvw192 -
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المساهمون: Department of Bio-engineering Sciences, Microbiology
مصطلحات موضوعية: Repressor Proteins/genetics, Gene Expression Profiling, Spores, Fungal/genetics, Protein Precursors/genetics, Cyclic AMP-Dependent Protein Kinases/metabolism, Microbiology, Fungal Proteins/genetics, Riboflavin/metabolism, Gene Expression Regulation, Fungal, Journal Article, meiosis, Saccharomyces cerevisiae Proteins/genetics, Transcription Factors/metabolism, Promoter Regions, Genetic, Eremothecium/genetics, Molecular Biology, Gene Deletion
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3848::f5d7c3418315434e0ea51b9b11779b70
https://doi.org/10.1111/mmi.13859 -
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المؤلفون: Sandrine Belouzard, Jens Bukh, Lucie Fénéant, Priscille Brodin, Yves Rouillé, Jean Dubuisson, Laura Riva, Thomas F. Baumert, Alexandre Vandeputte, François Helle, Jannick Prentoe, Laurent L'homme, Laurence Cocquerel, Charles-Henry Gattolliat, Ok-Ryul Song, Tarik Asselah
المساهمون: Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Copenhagen Hepatitis C Program [Copenhague, Danemark] (CO-HEP), Hvidovre Hospital-University of Copenhagen = Københavns Universitet (UCPH), Unité de Virologie clinique et fondamentale (UVCF), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 (RNMCD), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service d’Hépatologie [Hôpital Beaujon], Hôpital Beaujon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut de Recherche sur les Maladies Virales et Hépatiques (IVH), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de biologie de Lille - UMS 3702 (IBL), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), This work was supported by the French National Agency for Research on AIDS and Viral Hepatitis (ANRS) and the ANR through the ERA-NET Infect-ERA program (grant ANR-13-IFEC-0002-01). In addition, this study was supported by research grants from the Danish Council for Independent Research-Medical Sciences and the Novo Nordisk Foundation. The BioImaging Center Lille Nord-de-France is supported by the Equipex IMAGINEX program., The Copenhagen Hepatitis C Program (CO-HEP) is a joint venture of the Department of Infectious Diseases and Clinical Research Centre, Hvidovre Hospital, and the Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. We thank F. L. Cosset, C. Rice, and T. Wakita for providing essential reagents. We also thank S. Ung for his help in preparing the figures and L. Linna for manuscript proofreading. We are very grateful to A. Danneels for her precious help during the revisions. Immunofluorescence and flow cytometry analyses were performed with the help of the imaging core facility of the BioImaging Center Lille Nord-de-France., Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), University of Copenhagen = Københavns Universitet (KU)-Hvidovre Hospital, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Dubuisson, Jean, Centre d’Infection et d’Immunité de Lille (CIIL) - U1019 - UMR 8204 (CIIL), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), University of Copenhagen = Københavns Universitet (KU), Unité de Virologie clinique et fondamentale EA 4294, Récepteurs nucléaires, maladies cardiovasculaires et diabète (EGID), Université de Lille, Droit et Santé-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre de recherche sur l'Inflammation (CRI), Hôpital Beaujon, Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Université Paris Diderot - Paris 7 (UPD7)-Hôpital Beaujon
المصدر: Journal of Virology
Journal of Virology, 2018, 92 (10), pp.e01982-17. ⟨10.1128/JVI.01982-17⟩
Journal of Virology, American Society for Microbiology, 2018, 92 (10), pp.e01982-17. ⟨10.1128/JVI.01982-17⟩مصطلحات موضوعية: 0301 basic medicine, tight junction protein, hepatitis C virus, Cell, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Hepacivirus, virus entry, medicine.disease_cause, MESH: Cyclic AMP-Dependent Protein Kinases/antagonists & inhibitors, Piperazines, Receptors, G-Protein-Coupled, MESH: Virus Internalization/drug effects, MESH: Isoquinolines/pharmacology, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Claudin-1, MESH: Receptors, Serotonin/metabolism, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Sulfonamides, MESH: Claudin-1/metabolism, MESH: Cyclic AMP-Dependent Protein Kinases/metabolism, MESH: Protein Transport/drug effects, MESH: Protein Kinase Inhibitors/pharmacology, 3. Good health, Cell biology, Transport protein, Virus-Cell Interactions, MESH: Tetraspanin 28/metabolism, Protein Transport, medicine.anatomical_structure, [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Intracellular, MESH: Cell Line, Tumor, Hepatitis C virus, 030106 microbiology, Immunology, MESH: Sulfonamides/pharmacology, MESH: Tight Junctions/metabolism, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, MESH: Piperazines/pharmacology, Microbiology, Virus, piperazinylbenzenesulfonamide, Tetraspanin 28, Tight Junctions, 03 medical and health sciences, Viral entry, MESH: Receptors, G-Protein-Coupled/metabolism, Virology, Cell Line, Tumor, MESH: Hepacivirus/physiology, medicine, Humans, Protein kinase A, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Protein Kinase Inhibitors, MESH: Humans, virus-host interaction, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Virus Internalization, Isoquinolines, Cyclic AMP-Dependent Protein Kinases, [SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, 030104 developmental biology, Insect Science, MESH: Hepatocytes/virology, Receptors, Serotonin, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Hepatocytes, protein kinase A, CD81
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eede9d22a44a24224a0d9eb270333e63
https://pubmed.ncbi.nlm.nih.gov/29491159 -
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المؤلفون: Yannick Allanore, Nicolò Costantino Brembilla, Carlo Chizzolini, Marie-Elise Truchetet, Elisa Montanari
المصدر: Annals of the rheumatic diseases
Annals of the Rheumatic Diseases, Vol. 71, No 12 (2012) pp. 2044-50مصطلحات موضوعية: Male, Scleroderma, Systemic/drug therapy/immunology, medicine.medical_treatment, Adaptive Immunity, Interleukin-23 Subunit p19/metabolism, Monocytes, Cell Proliferation/drug effects, 0302 clinical medicine, Interleukins/metabolism, Immunology and Allergy, Interferon gamma, Cells, Cultured, ddc:616, Aged, 80 and over, 0303 health sciences, ddc:617, Interleukin-17, Th1 Cells/drug effects/immunology/metabolism, Interleukin, Antihypertensive Agents/pharmacology, Iloprost/pharmacology, Middle Aged, Acquired immune system, 3. Good health, medicine.anatomical_structure, Cytokine, Female, lipids (amino acids, peptides, and proteins), Monocytes/drug effects/immunology/metabolism, Interleukin 17, medicine.drug, Adult, Immunology, Cyclic AMP-Dependent Protein Kinases/metabolism, Peripheral blood mononuclear cell, General Biochemistry, Genetics and Molecular Biology, Th17 Cells/drug effects/immunology/metabolism, 03 medical and health sciences, Interferon-gamma, Young Adult, Rheumatology, Platelet Aggregation Inhibitors/pharmacology, medicine, Humans, Adaptive Immunity/drug effects/immunology, Iloprost, Prostacyclin receptor, Antihypertensive Agents, Interferon-gamma/metabolism, 030304 developmental biology, Aged, Cell Proliferation, Epoprostenol/analogs & derivatives/pharmacology, 030203 arthritis & rheumatology, Scleroderma, Systemic, business.industry, Monocyte, Interleukins, Th1 Cells, Cyclic AMP-Dependent Protein Kinases, Epoprostenol, Interleukin-17/metabolism, Interleukin-23 Subunit p19, Th17 Cells, business, Platelet Aggregation Inhibitors
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المؤلفون: Sörhede Winzell, Maria, Ahrén, Bo
المصدر: Journal of Molecular Endocrinology. 40(2):93-100
مصطلحات موضوعية: Islets of Langerhans: drug effects, Islets of Langerhans: cytology, Insulin: secretion, Fatty Acids: pharmacology, Fatty Acids: administration & dosage, Cyclic AMP-Dependent Protein Kinases: metabolism, Cyclic AMP-Dependent Protein Kinase Catalytic Subunits: metabolism, Cell Proliferation: drug effects, Caspase 7: metabolism, Caspase 3: metabolism, Body Weight: drug effects, Apoptosis: drug effects, Biological Markers: metabolism, Islets of Langerhans: enzymology, Islets of Langerhans: secretion, Peptides: administration & dosage, Peptides: pharmacology, Venoms: administration & dosage, Venoms: pharmacology, Medicin och hälsovetenskap, Klinisk medicin, Endokrinologi och diabetes, Medical and Health Sciences, Clinical Medicine, Endocrinology and Diabetes
URL الوصول: https://lup.lub.lu.se/record/1042471
http://www.ncbi.nlm.nih.gov/pubmed/18234911?dopt=Abstract
http://dx.doi.org/10.1677/JME-07-0121