المؤلفون: Lioux T; InvivoGen , 5 Rue Jean Rodier, 31400 Toulouse, France., Mauny MA; InvivoGen , 5 Rue Jean Rodier, 31400 Toulouse, France., Lamoureux A; InvivoGen , 5 Rue Jean Rodier, 31400 Toulouse, France., Bascoul N; InvivoGen , 5 Rue Jean Rodier, 31400 Toulouse, France., Hays M; InvivoGen , 5 Rue Jean Rodier, 31400 Toulouse, France., Vernejoul F; InvivoGen , 5 Rue Jean Rodier, 31400 Toulouse, France., Baudru AS; InvivoGen , 5 Rue Jean Rodier, 31400 Toulouse, France., Boularan C; InvivoGen , 5 Rue Jean Rodier, 31400 Toulouse, France., Lopes-Vicente J; InvivoGen , 5 Rue Jean Rodier, 31400 Toulouse, France., Qushair G; InvivoGen , 5 Rue Jean Rodier, 31400 Toulouse, France., Tiraby G; InvivoGen , 5 Rue Jean Rodier, 31400 Toulouse, France.

المصدر: Journal of medicinal chemistry [J Med Chem] 2016 Nov 23; Vol. 59 (22), pp. 10253-10267. Date of Electronic Publication: 2016 Nov 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Adenosine/*pharmacology , Cyclic IMP/*pharmacology , Cytokines/*metabolism , Interferon Type I/*metabolism, Adenosine/chemical synthesis ; Adenosine/chemistry ; Animals ; Cell Line ; Cyclic IMP/chemical synthesis ; Cyclic IMP/chemistry ; Dose-Response Relationship, Drug ; Humans ; Mice ; Molecular Structure ; Structure-Activity Relationship

المؤلفون: Nan Y; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China., Zeng X; Department of Pathophysiology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China., Jin Z; Department of Pathophysiology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China., Li N; Department of Pathophysiology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.; Department of Pathology, Wenzhou Central Hospital, Wenzhou, China., Chen Z; Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing, China., Chen J; Department of Pathophysiology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China., Wang D; Institute of Life Sciences, Wenzhou University, Wenzhou, China., Wang Y; Department of Pathophysiology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China., Lin Z; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China., Ying L; Department of Pathophysiology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.

المصدر: Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Dec; Vol. 24 (24), pp. 14514-14524. Date of Electronic Publication: 2020 Nov 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Coronary Vessels/*metabolism , Cyclic IMP/*metabolism , Cyclic Nucleotide Phosphodiesterases, Type 1/*metabolism , Cyclic Nucleotide Phosphodiesterases, Type 5/*metabolism , Nitric Oxide/*metabolism, Animals ; Chromatography, High Pressure Liquid ; Coronary Vessels/drug effects ; Cyclic GMP/metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 1/antagonists & inhibitors ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/metabolism ; Hypoxia/metabolism ; Metabolomics/methods ; Phosphodiesterase 5 Inhibitors/pharmacology ; Swine ; Tandem Mass Spectrometry ; Vasoconstriction

المؤلفون: Vanhoutte PM; Department of Pharmacology and Pharmacy, State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.; Department of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark, Odense, Denmark., Leung SWS; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, China.

المصدر: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2020 Aug; Vol. 127 (2), pp. 59-66. Date of Electronic Publication: 2019 Jul 29.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843 (Electronic) Linking ISSN: 17427835 NLM ISO Abbreviation: Basic Clin Pharmacol Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Endothelium, Vascular/*metabolism , Hypoxia/*metabolism , Muscle, Smooth, Vascular/*metabolism , Vasoconstriction/*physiology, Animals ; Calcium/metabolism ; Cyclic IMP/metabolism ; Endothelium, Vascular/physiopathology ; Humans ; Hypoxia/physiopathology ; Muscle, Smooth, Vascular/physiopathology ; NAD(P)H Dehydrogenase (Quinone)/metabolism ; Nitric Oxide/biosynthesis ; Soluble Guanylyl Cyclase/metabolism ; Vasoconstriction/drug effects ; Vasodilator Agents/pharmacology

المؤلفون: Moreau C; Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom., Wagner GK, Weber K, Guse AH, Potter BV

المصدر: Journal of medicinal chemistry [J Med Chem] 2006 Aug 24; Vol. 49 (17), pp. 5162-76.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: ADP-ribosyl Cyclase/*chemistry , Aplysia/*enzymology , Calcium/*metabolism , Cyclic IMP/*pharmacology , Inosine Diphosphate/*chemical synthesis , T-Lymphocytes/*drug effects, Animals ; Cyclic IMP/chemical synthesis ; Cyclic IMP/chemistry ; Cyclization ; Humans ; Hydrolysis ; Inosine Diphosphate/chemistry ; Jurkat Cells ; Molecular Conformation ; Stereoisomerism ; Structure-Activity Relationship ; T-Lymphocytes/metabolism

المؤلفون: Varnum MD; Department of Physiology and Biophysics, Seattle 98195, USA., Black KD, Zagotta WN

المصدر: Neuron [Neuron] 1995 Sep; Vol. 15 (3), pp. 619-25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print Cited Medium: Print ISSN: 0896-6273 (Print) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

مواضيع طبية MeSH: Ion Channel Gating*, Cyclic AMP/*pharmacology , Cyclic GMP/*pharmacology , Cyclic IMP/*pharmacology , Ion Channels/*physiology, Allosteric Site ; Amino Acid Sequence ; Animals ; Binding Sites ; Cattle ; Cyclic AMP/chemistry ; Cyclic GMP/chemistry ; Cyclic IMP/chemistry ; Cyclic Nucleotide-Gated Cation Channels ; Electric Conductivity ; Electrochemistry ; Hydrogen Bonding ; Ion Channels/chemistry ; Models, Molecular ; Molecular Sequence Data ; Protein Conformation ; Retinal Rod Photoreceptor Cells/chemistry ; Thermodynamics

المؤلفون: Leung SWS; Department of Pharmacology and Pharmacy, University of Hong Kong, 2/F, Laboratory Block, Li Ka Shing Faculty of Medicine Building, 21 Sassoon Road, Pokfulam, Hong Kong., Gao Y; Department of Physiology and Pathophysiology, Peking University Health Science Center, 38 Xue Yuan Road, Beijing, 100191, China., Vanhoutte PM; Department of Pharmacology and Pharmacy, University of Hong Kong, 2/F, Laboratory Block, Li Ka Shing Faculty of Medicine Building, 21 Sassoon Road, Pokfulam, Hong Kong. vanhoutt@hku.hk.

المصدر: Handbook of experimental pharmacology [Handb Exp Pharmacol] 2017; Vol. 238, pp. 209-228.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7902231 Publication Model: Print Cited Medium: Print ISSN: 0171-2004 (Print) Linking ISSN: 01712004 NLM ISO Abbreviation: Handb Exp Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Second Messenger Systems*, Blood Vessels/*metabolism , Cyclic IMP/*metabolism, Animals ; Cell Hypoxia ; Enzyme Activation ; Humans ; Nitric Oxide/metabolism ; Soluble Guanylyl Cyclase/metabolism

المؤلفون: Ng LCT; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Putrenko I; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Baronas V; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Van Petegem F; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Accili EA; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. Electronic address: eaaccili@mail.ubc.ca.

المصدر: Structure (London, England : 1993) [Structure] 2016 Oct 04; Vol. 24 (10), pp. 1629-1642. Date of Electronic Publication: 2016 Aug 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE

مواضيع طبية MeSH: Cyclic CMP/*metabolism , Cyclic IMP/*metabolism , Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels/*chemistry , Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels/*metabolism , Potassium Channels/*chemistry , Potassium Channels/*metabolism, Animals ; Binding Sites ; Crystallography, X-Ray ; Dynamic Light Scattering ; Mice ; Models, Molecular ; Protein Domains ; Protein Structure, Secondary

المؤلفون: Seifert R; Institute of Pharmacology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. seifert.roland@mh-hannover.de.

المصدر: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2016 Oct; Vol. 389 (10), pp. 1045-7. Date of Electronic Publication: 2016 Aug 18.

نوع المنشور: Editorial

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Second Messenger Systems*/drug effects, Cyclic IMP/*metabolism, Animals ; Benzoquinones/pharmacology ; Humans ; Species Specificity

المؤلفون: Detremmerie CM; Department of Pharmacology and Pharmacy and State Key Laboratory for Pharmaceutical Biotechnology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong S.A.R., China (C.M.D., Z.L., S.W.S.L., A.X., P.M.V.); Department of Clinical Pharmacy, King Saud University, Saudi Arabia (K.M.A.) and Department of Physiology and Pathophysiology, Peking University Health Science Centre, Beijing, China (Z.C., Y.G.) cdetremm@hku.hk., Chen Z; Department of Pharmacology and Pharmacy and State Key Laboratory for Pharmaceutical Biotechnology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong S.A.R., China (C.M.D., Z.L., S.W.S.L., A.X., P.M.V.); Department of Clinical Pharmacy, King Saud University, Saudi Arabia (K.M.A.) and Department of Physiology and Pathophysiology, Peking University Health Science Centre, Beijing, China (Z.C., Y.G.)., Li Z; Department of Pharmacology and Pharmacy and State Key Laboratory for Pharmaceutical Biotechnology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong S.A.R., China (C.M.D., Z.L., S.W.S.L., A.X., P.M.V.); Department of Clinical Pharmacy, King Saud University, Saudi Arabia (K.M.A.) and Department of Physiology and Pathophysiology, Peking University Health Science Centre, Beijing, China (Z.C., Y.G.)., Alkharfy KM; Department of Pharmacology and Pharmacy and State Key Laboratory for Pharmaceutical Biotechnology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong S.A.R., China (C.M.D., Z.L., S.W.S.L., A.X., P.M.V.); Department of Clinical Pharmacy, King Saud University, Saudi Arabia (K.M.A.) and Department of Physiology and Pathophysiology, Peking University Health Science Centre, Beijing, China (Z.C., Y.G.)., Leung SW; Department of Pharmacology and Pharmacy and State Key Laboratory for Pharmaceutical Biotechnology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong S.A.R., China (C.M.D., Z.L., S.W.S.L., A.X., P.M.V.); Department of Clinical Pharmacy, King Saud University, Saudi Arabia (K.M.A.) and Department of Physiology and Pathophysiology, Peking University Health Science Centre, Beijing, China (Z.C., Y.G.)., Xu A; Department of Pharmacology and Pharmacy and State Key Laboratory for Pharmaceutical Biotechnology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong S.A.R., China (C.M.D., Z.L., S.W.S.L., A.X., P.M.V.); Department of Clinical Pharmacy, King Saud University, Saudi Arabia (K.M.A.) and Department of Physiology and Pathophysiology, Peking University Health Science Centre, Beijing, China (Z.C., Y.G.)., Gao Y; Department of Pharmacology and Pharmacy and State Key Laboratory for Pharmaceutical Biotechnology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong S.A.R., China (C.M.D., Z.L., S.W.S.L., A.X., P.M.V.); Department of Clinical Pharmacy, King Saud University, Saudi Arabia (K.M.A.) and Department of Physiology and Pathophysiology, Peking University Health Science Centre, Beijing, China (Z.C., Y.G.)., Vanhoutte PM; Department of Pharmacology and Pharmacy and State Key Laboratory for Pharmaceutical Biotechnology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong S.A.R., China (C.M.D., Z.L., S.W.S.L., A.X., P.M.V.); Department of Clinical Pharmacy, King Saud University, Saudi Arabia (K.M.A.) and Department of Physiology and Pathophysiology, Peking University Health Science Centre, Beijing, China (Z.C., Y.G.).

المصدر: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2016 Sep; Vol. 358 (3), pp. 558-68. Date of Electronic Publication: 2016 Jun 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

مواضيع طبية MeSH: Arteries/*drug effects , Arteries/*physiology , Benzoquinones/*pharmacology , Cyclic IMP/*biosynthesis , Endothelium, Vascular/*drug effects , Soluble Guanylyl Cyclase/*metabolism , Vasoconstriction/*drug effects, Animals ; Arteries/metabolism ; Benzoquinones/chemistry ; Endothelium, Vascular/metabolism ; Male ; Rats ; Rats, Sprague-Dawley

المؤلفون: Řlepokura KA; Faculty of Chemistry, University of Wrocław, 14 Joliot-Curie St, 50-383 Wrocław, Poland.

المصدر: Acta crystallographica. Section C, Structural chemistry [Acta Crystallogr C Struct Chem] 2016 Jun 01; Vol. 72 (Pt 6), pp. 465-79. Date of Electronic Publication: 2016 May 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: International Union of Crystallography Country of Publication: England NLM ID: 101620313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2053-2296 (Electronic) Linking ISSN: 20532296 NLM ISO Abbreviation: Acta Crystallogr C Struct Chem Subsets: MEDLINE

مواضيع طبية MeSH: Cyclic AMP/*chemistry , Cyclic GMP/*chemistry , Cyclic IMP/*chemistry, Crystallography, X-Ray ; Hydrogen Bonding ; Models, Molecular