المؤلفون: Loana Musso, Raquel T. Lima, Raffaella Cincinelli, Ana Bizarro, Michelandrea De Cesare, Sabrina Dallavalle, M. Helena Vasconcelos, Valentina Zuco, Diana Sousa

المساهمون: Instituto de Investigação e Inovação em Saúde

المصدر: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 2, p 407 (2018)
Molecules; Volume 23; Issue 2; Pages: 407
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: Skin Neoplasms, Skin Neoplasms / drug therapy, Antineoplastic Agents / pharmacology, Apoptosis, 01 natural sciences, Analytical Chemistry, Inhibitor of Apoptosis Proteins, Mice, HSP90 Heat-Shock Proteins / metabolism, Drug Discovery, Carcinoma, Squamous Cell / drug therapy, HSP90 Heat-Shock Proteins / antagonists & inhibitors, Cell Cycle, raf Kinases / antagonists & inhibitors, Benzopyrans / chemical synthesis, 3. Good health, Tumor Burden, Gene Expression Regulation, Neoplastic, Cyclin-Dependent Kinase 4 / genetics, Chemistry (miscellaneous), Carcinoma, Squamous Cell, Growth inhibition, Pyridones, Proto-Oncogene Proteins c-akt / metabolism, Antineoplastic Agents, Apoptosis / drug effects, tumor xenographs, Article, (thio)chromenopyridinones, 03 medical and health sciences, Inhibitory Concentration 50, Cyclin-Dependent Kinase 4 / metabolismo, Proto-Oncogene Proteins c-akt / genetics, lcsh:Organic chemistry, Humans, Benzopyrans, raf Kinases / metabolism, Apoptosis / genetics, Isoxazoles, Proto-Oncogene Proteins c-akt / antagonists & inhibitors, 0104 chemical sciences, 030104 developmental biology, chemistry, Inhibitor of Apoptosis Proteins / genetics, Pyridones / pharmacology, 0301 basic medicine, Carcinoma, Squamous Cell / genetics, Survivin, Pharmaceutical Science, raf Kinases / genetics, chemistry.chemical_compound, HSP90, naphthoquinones, antitumor, cell proliferation, cell cycle, apoptosis, Carcinoma, Squamous Cell / pathology, Antineoplastic Agents / chemical synthesis, Benzopyrans / pharmacology, Skin Neoplasms / genetics, Inhibitor of Apoptosis Proteins / antagonists & inhibitors, biology, Cell cycle, Cyclin-Dependent Kinase 4 / antagonists & inhibitors, Hsp90, Molecular Medicine, Female, raf Kinases, Signal transduction, Signal Transduction, Carcinoma, Squamous Cell / metabolism, Isoxazoles / pharmacology, Mice, Nude, Cell Cycle / drug effects, Skin Neoplasms / metabolismo, lcsh:QD241-441, Isoxazoles / chemical synthesis, Tumor Burden / drug effects, Heat shock protein, Cell Line, Tumor, Animals, HSP90 Heat-Shock Proteins, Physical and Theoretical Chemistry, Cell Proliferation, Skin Neoplasms / pathology, Pyridones / chemical synthesis, Cell growth, Organic Chemistry, Cyclin-Dependent Kinase 4, Xenograft Model Antitumor Assays, Inhibitor of Apoptosis Proteins / metabolism, 010404 medicinal & biomolecular chemistry, HSP90 Heat-Shock Proteins / genetics, Cell culture, Cancer research, biology.protein, Cell Proliferation / drug effects, Proto-Oncogene Proteins c-akt

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638850e929e3ec4d77bf8fdf3caa98da
http://europepmc.org/articles/PMC6017909

المؤلفون: Xavier Bisteau, Pierre P. Roger, Laurence Bockstaele, Sabine Paternot

المصدر: Molecular and cellular biology, 29 (15

مصطلحات موضوعية: Threonine, Cyclin-Dependent Kinases -- genetics, Cyclins -- metabolism, Cyclin A, environment and public health, Threonine -- metabolism, Cyclins -- genetics, Cricetinae, Cyclin-Dependent Kinase 4 -- genetics, Protein phosphorylation, Cyclin-Dependent Kinase 6 -- genetics, Electrophoresis, Gel, Two-Dimensional, Cyclin D3, Phosphorylation, Fluorescent Antibody Technique, Indirect, Cyclin-Dependent Kinase 6 -- metabolism, Kinase, Articles, Sciences bio-médicales et agricoles, Cyclin-Dependent Kinases, Proline -- genetics, biological phenomena, cell phenomena, and immunity, Cyclin-Dependent Kinases -- metabolism, Protein Binding, Proline, Blotting, Western, Molecular Sequence Data, CHO Cells, Biology, Transfection, Cell Line, Cricetulus, Cyclin-dependent kinase, Cyclins, Cell Line, Tumor, Animals, Humans, Immunoprecipitation, Amino Acid Sequence, Molecular Biology, Proline -- metabolism, Sequence Homology, Amino Acid, Cyclin-dependent kinase 4, Cyclin-Dependent Kinase 4, Cell Biology, Cyclin-Dependent Kinase 6, Cyclin-Dependent Kinase 4 -- metabolism, HCT116 Cells, Molecular biology, enzymes and coenzymes (carbohydrates), Mutation, biology.protein, Cyclin-dependent kinase complex, Threonine -- genetics, Cyclin A2, Cyclin-Dependent Kinase-Activating Kinase

وصف الملف: 1 full-text file(s): application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3045ed052a7fa1ea1a750ce63dc6e5
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/51536

المؤلفون: Xavier Bisteau, Ludger Hengst, Wim Declercq, Katia Coulonval, Pierre P. Roger, Bianca Colleoni, Sabine Paternot, Philippe De Groote, Karin Ecker

المصدر: PLOS genetics, 9 (5
PLoS Genetics
PLOS GENETICS
PLoS Genetics, Vol 9, Iss 5, p e1003546 (2013)

مصطلحات موضوعية: Cancer Research, CHEMICAL GENETICS, Tumor Physiology, Cancer Treatment, MURINE FIBROBLASTS, Sciences biomédicales en général, Biochemistry, Mitogenic Signaling, environment and public health, Phosphorylation cascade, 0302 clinical medicine, Cyclin-Dependent Kinase 2 -- genetics -- metabolism, Molecular Cell Biology, Basic Cancer Research, G1 Phase Cell Cycle Checkpoints -- genetics, Signaling in Cellular Processes, Protein phosphorylation, Phosphorylation, Genetics (clinical), 0303 health sciences, Protein Kinase Signaling Cascade, integumentary system, Physiologie de la régulation, Kinase, Mechanisms of Signal Transduction, Drug Information, cdc25 Phosphatases -- metabolism, p21-Activated Kinases -- genetics -- metabolism, Signaling Cascades, Cyclin-Dependent Kinases, Cell biology, Nucleic acids, Mitotic Signaling, Oncology, Cyclin-Dependent Kinase 4 -- genetics -- metabolism, CYCLIN-DEPENDENT KINASES, 030220 oncology & carcinogenesis, Medicine, Cyclin-Dependent Kinases -- genetics -- metabolism, biological phenomena, cell phenomena, and immunity, SUBCELLULAR-LOCALIZATION, Restriction point, Cell Division, Research Article, Biotechnology, Signal Transduction, Protein Binding, Drugs and Devices, Feedback Regulation, lcsh:QH426-470, 2-DIMENSIONAL GEL-ELECTROPHORESIS, T-LOOP, PHARMACOLOGICAL INHIBITION, Biology, THYROID EPITHELIAL-CELLS, 03 medical and health sciences, Cyclin-dependent kinase, Cyclins, Genetics, cdc25 Phosphatases, Humans, Croissance et développement [humain], Protein Interactions, neoplasms, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Cyclin-dependent kinase 1, DNA synthesis, Croissance et développement [animal], Cell Cycle Checkpoints -- genetics, ACTIVATING KINASE, Cyclin-Dependent Kinase 2, Cyclin-dependent kinase 2, Biology and Life Sciences, Proteins, Cyclin-Dependent Kinase 4, DNA, Cell Cycle Checkpoints, Chemotherapy and Drug Treatment, HCT116 Cells, G1 Phase Cell Cycle Checkpoints, Molecular biology, Sciences biomédicales, Regulatory Proteins, lcsh:Genetics, enzymes and coenzymes (carbohydrates), MAMMALIAN TARGET, p21-Activated Kinases, Small Molecules, Mutation, biology.protein, Gene Function, Mitogens, Cyclin-Dependent Kinase-Activating Kinase

وصف الملف: 2 full-text file(s): application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a805b11b2fa196116ccce1ba880e312
https://doi.org/10.1371/journal.pgen.1003546

المصدر: PLOS genetics, 9 (5

مصطلحات الفهرس: Sciences biomédicales en général, Physiologie de la régulation, Croissance et développement [humain], Croissance et développement [animal], Sciences biomédicales, Cell Cycle Checkpoints -- genetics, Cyclin-Dependent Kinase 2 -- genetics -- metabolism, Cyclin-Dependent Kinase 4 -- genetics -- metabolism, Cyclin-Dependent Kinases -- genetics -- metabolism, G1 Phase Cell Cycle Checkpoints -- genetics, HCT116 Cells, Humans, Mutation, Phosphorylation, Protein Binding, cdc25 Phosphatases -- metabolism, p21-Activated Kinases -- genetics -- metabolism, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: https://dipot.ulb.ac.be/dspace/bitstream/2013/149585/4/doi_133756.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/149585/1/BisteauPaternot2013full.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/149585
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL

المصدر: Molecular and cellular biology, 29 (15

مصطلحات الفهرس: Sciences bio-médicales et agricoles, Amino Acid Sequence, Animals, Blotting, Western, CHO Cells, Cell Line, Cell Line, Tumor, Cricetinae, Cricetulus, Cyclin D3, Cyclin-Dependent Kinase 4 -- genetics, Cyclin-Dependent Kinase 4 -- metabolism, Cyclin-Dependent Kinase 6 -- genetics, Cyclin-Dependent Kinase 6 -- metabolism, Cyclin-Dependent Kinases -- genetics, Cyclin-Dependent Kinases -- metabolism, Cyclins -- genetics, Cyclins -- metabolism, Electrophoresis, Gel, Two-Dimensional, Fluorescent Antibody Technique, Indirect, HCT116 Cells, Humans, Immunoprecipitation, Molecular Sequence Data, Mutation, Phosphorylation, Proline -- genetics, Proline -- metabolism, Protein Binding, Sequence Homology, Amino Acid, Threonine -- genetics, Threonine -- metabolism, Transfection, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: https://dipot.ulb.ac.be/dspace/bitstream/2013/51536/4/doi_26644.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/51536
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL