المؤلفون: Holanda VAD; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador salgado Filho, 3000, Campus Universitário - Lagoa Nova, Natal, 59078-900, Brazil., de Almeida RN; Department of Physiology and Behavior and Postgraduate Program in Psychobiology, Federal University of Rio Grande do Norte, Natal, Brazil., de Oliveira MC; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador salgado Filho, 3000, Campus Universitário - Lagoa Nova, Natal, 59078-900, Brazil., da Silva Junior ED; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador salgado Filho, 3000, Campus Universitário - Lagoa Nova, Natal, 59078-900, Brazil., Galvão-Coelho NL; Department of Physiology and Behavior and Postgraduate Program in Psychobiology, Federal University of Rio Grande do Norte, Natal, Brazil., Calo' G; Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy., Ruzza C; Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy.; LTTA Laboratory for Advanced Therapies, Technopole of Ferrara, Ferrara, Italy., Gavioli EC; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador salgado Filho, 3000, Campus Universitário - Lagoa Nova, Natal, 59078-900, Brazil. egavioli@hotmail.com.

المصدر: Psychopharmacology [Psychopharmacology (Berl)] 2024 May; Vol. 241 (5), pp. 1001-1010. Date of Electronic Publication: 2024 Jan 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Opioid*/physiology , Opioid Peptides*/metabolism , Cycloheptanes* , Imidazoles* , Piperidines* , Spiro Compounds*, Mice ; Animals ; Glucocorticoids/pharmacology ; Nortriptyline/pharmacology ; Nociceptin Receptor ; Corticosterone/pharmacology ; Hypothalamo-Hypophyseal System/metabolism ; Mifepristone/pharmacology ; Pituitary-Adrenal System/metabolism

المؤلفون: Maity J; Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA., Barthels D; Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA., Sarkar J; Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA., Prateeksha P; Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA., Deb M; Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA., Rolph D; Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA., Das H; Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA. hiranmoy.das@ttuhsc.edu.

المصدر: Cell death & disease [Cell Death Dis] 2022 May 12; Vol. 13 (5), pp. 452. Date of Electronic Publication: 2022 May 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

مواضيع طبية MeSH: Cycloheptanes*/pharmacology , Mitophagy*, Autophagy/genetics ; Benzoates ; Bridged Bicyclo Compounds ; Cell Differentiation/genetics ; Cells, Cultured ; Osteoblasts ; Sesquiterpenes ; Transcription Factors/pharmacology

المؤلفون: Hammam AMM; Department of Animal Reproduction & A.I., Veterinary Research Division, National Research Centre, Dokki, Egypt., Elmotayam AK; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Kasr el-Aini Street, Cairo, 11562, Egypt., Elnattat WM; Department of Animal Reproduction & A.I., Veterinary Research Division, National Research Centre, Dokki, Egypt., Ali GA; Department of Animal Reproduction & A.I., Veterinary Research Division, National Research Centre, Dokki, Egypt., Madbouly AEM; Department of Animal Reproduction & A.I., Veterinary Research Division, National Research Centre, Dokki, Egypt., El Khatteb RM; Department of Parasitology and Animal Diseases, Veterinary Research Division, National Research Centre, Dokki, Egypt., Abdelhameed MF; Department of Pharmacology, Medical Research Division, National Research Centre, Dokki, Egypt., Ali AH; Department of Animal Reproduction & A.I., Veterinary Research Division, National Research Centre, Dokki, Egypt., Qasim S; Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf, 72341, Saudi Arabia., Ahmed SR; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Kasr el-Aini Street, Cairo, 11562, Egypt; Department of Pharmacognosy, College of Pharmacy, Jouf University, Sakaka, Aljouf, 72341, Saudi Arabia. Electronic address: srmorsi@ju.edu.sa.

المصدر: Journal of ethnopharmacology [J Ethnopharmacol] 2022 May 10; Vol. 289, pp. 115062. Date of Electronic Publication: 2022 Feb 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Benzoates/*pharmacology , Cycloheptanes/*pharmacology , Fertility Agents/*pharmacology , Ferula/*chemistry , Plant Extracts/*pharmacology , Sesquiterpenes/*pharmacology, Animals ; Benzoates/isolation & purification ; Bridged Bicyclo Compounds/isolation & purification ; Bridged Bicyclo Compounds/pharmacology ; Chromatography, High Pressure Liquid ; Cycloheptanes/isolation & purification ; Female ; Fertility ; Fertility Agents/isolation & purification ; Follicle Stimulating Hormone/metabolism ; Luteinizing Hormone/metabolism ; Molecular Docking Simulation ; Rats ; Sesquiterpenes/isolation & purification

المؤلفون: Ponzar NL; Department of Molecular Microbiology and Immunology, Saint Louis University, Saint Louis, Missouri USA; Institute for Drug and Biotherapeutic Innovation, Saint Louis University, Saint Louis, Missouri USA., Tajwar R; Department of Molecular Microbiology and Immunology, Saint Louis University, Saint Louis, Missouri USA; Institute for Drug and Biotherapeutic Innovation, Saint Louis University, Saint Louis, Missouri USA., Pozzi N; Institute for Drug and Biotherapeutic Innovation, Saint Louis University, Saint Louis, Missouri USA; Department of Biochemistry and Molecular Biology, Saint Louis University, Saint Louis, Missouri USA., Tavis JE; Department of Molecular Microbiology and Immunology, Saint Louis University, Saint Louis, Missouri USA; Institute for Drug and Biotherapeutic Innovation, Saint Louis University, Saint Louis, Missouri USA; Liver Center, Saint Louis, Missouri USA. Electronic address: john.tavis@health.slu.edu.

المصدر: The Journal of biological chemistry [J Biol Chem] 2022 Apr; Vol. 298 (4), pp. 101790. Date of Electronic Publication: 2022 Mar 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Cycloheptanes*/metabolism , Cycloheptanes*/pharmacology , Protein Binding*/drug effects, Catalytic Domain ; Enzyme Inhibitors/metabolism ; Enzyme Inhibitors/pharmacology ; Humans ; Kinetics ; Ribonuclease H/chemistry

المؤلفون: Naji Reyhani Garmroudi S; Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran., Karimi E; Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran., Oskoueian E; Mashhad Branch, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education, and Extension Organization (AREEO), Mashhad, Iran., Homayouni-Tabrizi M; Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran., Iranshahi M; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

المصدر: Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2021 Apr; Vol. 35 (4), pp. e22713. Date of Electronic Publication: 2021 Jan 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 9717231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-0461 (Electronic) Linking ISSN: 10956670 NLM ISO Abbreviation: J Biochem Mol Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents, Phytogenic/*pharmacology , Antioxidants/*pharmacology , Benzoates/*pharmacology , Breast Neoplasms/*drug therapy , Cycloheptanes/*pharmacology , Ferula/*chemistry , Phytoestrogens/*pharmacology , Sesquiterpenes/*pharmacology, Animals ; Antineoplastic Agents, Phytogenic/chemistry ; Antioxidants/chemistry ; Benzoates/chemistry ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Bridged Bicyclo Compounds/chemistry ; Bridged Bicyclo Compounds/pharmacology ; Cycloheptanes/chemistry ; Drug Screening Assays, Antitumor ; Female ; Humans ; MCF-7 Cells ; Male ; Mice ; Mice, Inbred BALB C ; Phytoestrogens/chemistry ; Sesquiterpenes/chemistry

المؤلفون: Macrì R; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Musolino V; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Gliozzi M; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Carresi C; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Maiuolo J; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Nucera S; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Scicchitano M; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Bosco F; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Scarano F; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Ruga S; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Zito MC; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Guarnieri L; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy., Bombardelli E; Nutramed S.c.a.r.l., Complesso Ninì Barbieri, Roccelletta di Borgia, 88021 Catanzaro, Italy., Mollace V; Institute of Research for Food Safety & Health IRC-FSH, University Magna Graecia, 88100 Catanzaro, Italy.; Nutramed S.c.a.r.l., Complesso Ninì Barbieri, Roccelletta di Borgia, 88021 Catanzaro, Italy.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2020 Dec 07; Vol. 25 (23). Date of Electronic Publication: 2020 Dec 07.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Antioxidants/*pharmacology , Benzoates/*pharmacology , Cycloheptanes/*pharmacology , Ferula/*chemistry , Plant Extracts/*pharmacology , Sesquiterpenes/*pharmacology, Antineoplastic Agents/chemistry ; Antineoplastic Agents/therapeutic use ; Antioxidants/chemistry ; Antioxidants/therapeutic use ; Apoptosis/drug effects ; Benzoates/chemistry ; Benzoates/therapeutic use ; Bridged Bicyclo Compounds/chemistry ; Bridged Bicyclo Compounds/pharmacology ; Bridged Bicyclo Compounds/therapeutic use ; Cell Line, Tumor ; Cycloheptanes/chemistry ; Cycloheptanes/therapeutic use ; Dose-Response Relationship, Drug ; Electron Transport/drug effects ; Hormone Replacement Therapy ; Humans ; Mitochondria/drug effects ; Mitochondria/metabolism ; Nitric Oxide/metabolism ; Phytochemicals/chemistry ; Phytochemicals/pharmacology ; Phytoestrogens/chemistry ; Phytoestrogens/pharmacology ; Plant Extracts/chemistry ; Plant Extracts/therapeutic use ; Reactive Oxygen Species/metabolism ; Sesquiterpenes/chemistry ; Sesquiterpenes/therapeutic use

المؤلفون: Salomon E; Université de Haute-Alsace, Université de Strasbourg, CNRS, LIMA UMR 7042, F-68000 Mulhouse, France., Schmitt M; Université de Haute-Alsace, Université de Strasbourg, CNRS, LIMA UMR 7042, F-68000 Mulhouse, France., Mouray E; Unité Molécules de Communication et Adaptation des Micro-organismes, UMR7245, Muséum National d'Histoire Naturelle, CNRS, Sorbonne Universités, Paris, France., McEwen AG; Institut de Génétique et de Biologie Moléculaire et Cellulaire, UMR7104, INSERM U1258, Université de Strasbourg, CNRS, Illkirch, France., Bounaadja L; Unité Molécules de Communication et Adaptation des Micro-organismes, UMR7245, Muséum National d'Histoire Naturelle, CNRS, Sorbonne Universités, Paris, France., Torchy M; Institut de Génétique et de Biologie Moléculaire et Cellulaire, UMR7104, INSERM U1258, Université de Strasbourg, CNRS, Illkirch, France., Poussin-Courmontagne P; Institut de Génétique et de Biologie Moléculaire et Cellulaire, UMR7104, INSERM U1258, Université de Strasbourg, CNRS, Illkirch, France., Alavi S; Université de Haute-Alsace, Université de Strasbourg, CNRS, LIMA UMR 7042, F-68000 Mulhouse, France., Tarnus C; Université de Haute-Alsace, Université de Strasbourg, CNRS, LIMA UMR 7042, F-68000 Mulhouse, France., Cavarelli J; Institut de Génétique et de Biologie Moléculaire et Cellulaire, UMR7104, INSERM U1258, Université de Strasbourg, CNRS, Illkirch, France., Florent I; Unité Molécules de Communication et Adaptation des Micro-organismes, UMR7245, Muséum National d'Histoire Naturelle, CNRS, Sorbonne Universités, Paris, France., Albrecht S; Université de Haute-Alsace, Université de Strasbourg, CNRS, LIMA UMR 7042, F-68000 Mulhouse, France. Electronic address: sebastien.albrecht@uha.fr.

المصدر: Bioorganic chemistry [Bioorg Chem] 2020 May; Vol. 98, pp. 103750. Date of Electronic Publication: 2020 Mar 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Aminopeptidases/*antagonists & inhibitors , Anisoles/*pharmacology , Antimalarials/*pharmacology , Cycloheptanes/*pharmacology , Enzyme Inhibitors/*pharmacology , Plasmodium falciparum/*drug effects, Aminopeptidases/metabolism ; Anisoles/chemical synthesis ; Anisoles/chemistry ; Antimalarials/chemical synthesis ; Antimalarials/chemistry ; Cycloheptanes/chemical synthesis ; Cycloheptanes/chemistry ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Molecular Structure ; Parasitic Sensitivity Tests ; Plasmodium falciparum/enzymology ; Structure-Activity Relationship

المؤلفون: Safi R; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.; Department of Chemistry and Biochemistry, Laboratoire d'Innovation Thérapeutique, Faculty of Sciences II, Lebanese University, Beirut, Lebanon., El-Sabban M; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon., Najjar F; Department of Chemistry and Biochemistry, Laboratoire d'Innovation Thérapeutique, Faculty of Sciences II, Lebanese University, Beirut, Lebanon.

المصدر: Current drug targets [Curr Drug Targets] 2020; Vol. 21 (5), pp. 499-508.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 100960531 Publication Model: Print Cited Medium: Internet ISSN: 1873-5592 (Electronic) Linking ISSN: 13894501 NLM ISO Abbreviation: Curr Drug Targets Subsets: MEDLINE

مواضيع طبية MeSH: Benzoates/*pharmacology , Cycloheptanes/*pharmacology , Ferula/*chemistry , Phytoestrogens/*pharmacology , Plant Extracts/*pharmacology , Sesquiterpenes/*pharmacology, Animals ; Benzoates/chemistry ; Benzoates/therapeutic use ; Bridged Bicyclo Compounds/chemistry ; Bridged Bicyclo Compounds/pharmacology ; Bridged Bicyclo Compounds/therapeutic use ; Cycloheptanes/chemistry ; Cycloheptanes/therapeutic use ; Esters/chemistry ; Humans ; Phytochemicals/chemistry ; Phytochemicals/pharmacology ; Phytochemicals/therapeutic use ; Phytoestrogens/chemistry ; Phytoestrogens/therapeutic use ; Plant Extracts/chemistry ; Plant Extracts/therapeutic use ; Sesquiterpenes/chemistry ; Sesquiterpenes/therapeutic use

المؤلفون: McVeigh MS; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, United States., Kelleghan AV; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, United States., Yamano MM; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, United States., Knapp RR; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, United States., Garg NK; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, United States.

المصدر: Organic letters [Org Lett] 2020 Jun 05; Vol. 22 (11), pp. 4500-4504. Date of Electronic Publication: 2020 May 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

مواضيع طبية MeSH: Cycloheptanes/*chemical synthesis , Cyclohexenes/*chemical synthesis , Silanes/*chemistry , Tosyl Compounds/*chemistry, Cycloaddition Reaction ; Cycloheptanes/chemistry ; Cyclohexenes/chemistry ; Molecular Structure ; Stereoisomerism

المؤلفون: Hobbs H; GlaxoSmithKline R&D , Gunnels Wood Road , Stevenage SG1 2NY , U.K., Bravi G; GlaxoSmithKline R&D , Gunnels Wood Road , Stevenage SG1 2NY , U.K., Campbell I; GlaxoSmithKline R&D , Gunnels Wood Road , Stevenage SG1 2NY , U.K., Convery M; GlaxoSmithKline R&D , Gunnels Wood Road , Stevenage SG1 2NY , U.K., Davies H; GlaxoSmithKline R&D , Gunnels Wood Road , Stevenage SG1 2NY , U.K., Inglis G; GlaxoSmithKline R&D , Gunnels Wood Road , Stevenage SG1 2NY , U.K., Pal S; GlaxoSmithKline R&D , Gunnels Wood Road , Stevenage SG1 2NY , U.K., Peace S; GlaxoSmithKline R&D , Gunnels Wood Road , Stevenage SG1 2NY , U.K., Redmond J; GlaxoSmithKline R&D , Gunnels Wood Road , Stevenage SG1 2NY , U.K., Summers D; GlaxoSmithKline R&D , Gunnels Wood Road , Stevenage SG1 2NY , U.K.

المصدر: Journal of medicinal chemistry [J Med Chem] 2019 Aug 08; Vol. 62 (15), pp. 6972-6984. Date of Electronic Publication: 2019 Jul 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Phosphatidylinositol 3-Kinases*/metabolism, Bridged Bicyclo Compounds/*chemistry , Cycloheptanes/*chemistry , Morpholines/*chemistry , Phosphoinositide-3 Kinase Inhibitors/*chemistry , Proto-Oncogene Proteins c-akt/*antagonists & inhibitors , TOR Serine-Threonine Kinases/*antagonists & inhibitors, Bridged Bicyclo Compounds/pharmacology ; Cycloheptanes/pharmacology ; Drug Discovery/methods ; Humans ; Morpholines/pharmacology ; Phosphoinositide-3 Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects ; Signal Transduction/physiology ; TOR Serine-Threonine Kinases/metabolism