المؤلفون: Sandra M.W. van de Wiel, Begoña Porteiro, Saskia C. Belt, Esther W.M. Vogels, Isabelle Bolt, Jacqueline L.M. Vermeulen, D. Rudi de Waart, Joanne Verheij, Vanesa Muncan, Ronald P.J. Oude Elferink, Stan F.J. van de Graaf

المصدر: JHEP Reports, Vol 4, Iss 5, Pp 100463- (2022)

مصطلحات موضوعية: ASBT, NTCP, BSEP, Cholestasis, SLC51A, diarrhea, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555922000350; https://doaj.org/toc/2589-5559

URL الوصول: https://doaj.org/article/210c016cca024c84beb00f9762b19ffb

المؤلفون: Sandra M.W. van de Wiel, D. Rudi de Waart, Ronald P.J. Oude Elferink, Stan F.J. van de Graaf

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 223-237 (2018)

مصطلحات موضوعية: Fluorescence Resonance Energy Transfer (FRET), FXR, OSTα-OSTβ, Bile Acids, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X17301662; https://doaj.org/toc/2352-345X

URL الوصول: https://doaj.org/article/16283c7096e24109b3d7d991d41c0949

المؤلفون: Steven W.M. Olde Damink, Serge J. Zweers, Cyriel Y. Ponsioen, Frank G. Schaap, Elisabeth M.G. de Vries, Dagmar Tolenaars, D. Rudi de Waart, Ulrich Beuers, Albert K. Groen, Martin Lenicek, Kiran V. K. Koelfat, Peter L.M. Jansen

المساهمون: Center for Liver, Digestive and Metabolic Diseases (CLDM), Lifestyle Medicine (LM), Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Graduate School, Tytgat Institute for Liver and Intestinal Research, Other departments, ACS - Diabetes & metabolism, Experimental Vascular Medicine, ACS - Atherosclerosis & ischemic syndromes, Promovendi NTM, Surgery, RS: NUTRIM - R2 - Liver and digestive health, RS: NUTRIM - R2 - Gut-liver homeostasis, MUMC+: MA Heelkunde (9), Huisartsgeneeskunde

المصدر: Hepatology International, 11(1), 132-140. SPRINGER
Hepatology international, 11(1), 132-140. Springer New York
Hepatology International, 11(1), 132-140. Springer
Hepatology International

مصطلحات موضوعية: 0301 basic medicine, Male, LIVER, FIBROBLAST-GROWTH-FACTOR-19, Administration, Oral, Gastroenterology, DISEASE, chemistry.chemical_compound, 0302 clinical medicine, Clinical Protocols, Chenodeoxycholic acid, HEPATOCELLULAR-CARCINOMA, Intestinal Mucosa, Receptor, Liver injury, Fibroblast growth factor 19, Cathartics, Primary sclerosing cholangitis, digestive, oral, and skin physiology, Middle Aged, Biomarker (medicine), 030211 gastroenterology & hepatology, Original Article, Female, FARNESOID-X-RECEPTOR, Agonist, Adult, EXPRESSION, medicine.medical_specialty, medicine.drug_class, Cholangitis, Sclerosing, digestive system, 03 medical and health sciences, Farnesoid X receptor, Internal medicine, medicine, Humans, Cholestenones, Aged, PRIMARY BILIARY-CIRRHOSIS, Hepatology, business.industry, FGF19, medicine.disease, digestive system diseases, Fibroblast Growth Factors, MODEL, MICE, 030104 developmental biology, Endocrinology, chemistry, Case-Control Studies, BILE, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c714b22908b661e7a59e65d241048f8b
https://doi.org/10.1007/s12072-016-9769-7

المؤلفون: Ronald P.J. Oude Elferink, D. Rudi de Waart, Sandra M. W. van de Wiel, Stan F.J. van de Graaf

المساهمون: Gastroenterology and Hepatology, Graduate School, AGEM - Endocrinology, metabolism and nutrition, Tytgat Institute for Liver and Intestinal Research, AGEM - Digestive immunity, ACS - Atherosclerosis & ischemic syndromes

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, 5(3), 223-237. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 223-237 (2018)

مصطلحات موضوعية: 0301 basic medicine, MDCKII, Madin–Darby canine kidney epithelial cells, medicine.drug_class, 03 medical and health sciences, Bile Acids, FXR, farnesoid X receptor, FACS, fluorescence-activated cell sorting, medicine, nucleoBAS, nucleus-localized bile acid sensor, lcsh:RC799-869, FRET, fluorescent resonance energy transfer, TCDCA, taurochenodeoxycholic acid, Epithelial polarity, Original Research, U2OS, human bone osteosarcoma epithelial cells, Hepatology, Bile acid, OSTα-OSTβ, organic solute transporter α-β, Chemistry, TICE, transintestinal cholesterol excretion, Gastroenterology, Transporter, FGF15/19, fibroblast growth factor 15/19, FDA, Food and Drug Administration, mRNA, messenger RNA, 3. Good health, Cell biology, 030104 developmental biology, Nuclear receptor, Biochemistry, FXR, FGF15/19, OSTα-OSTβ, Paracellular transport, Farnesoid X receptor, lcsh:Diseases of the digestive system. Gastroenterology, Efflux, ASBT, apical sodium-dependent bile acid transporter, Fluorescence Resonance Energy Transfer (FRET), BAS, bile acid sensor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2148aac15134926b8e3da154af5a78f6
https://pubmed.ncbi.nlm.nih.gov/29675448

المؤلفون: Vincent A. van der Mark, Heleen W. Voogt, Ronald P.J. Oude Elferink, D. Rudi de Waart, Coen C. Paulusma, A.S. Knisely, Merit M. Tabbers, Kam S. Ho-Mok

المساهمون: Graduate School, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Tytgat Institute for Liver and Intestinal Research, Paediatric Gastroenterology, Other departments, AII - Amsterdam institute for Infection and Immunity

المصدر: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1842(12 Part A), 2378-2386. Elsevier

مصطلحات موضوعية: Taurocholic Acid, Enterohepatic circulation, Diarrhea, medicine.medical_specialty, medicine.drug_class, Blotting, Western, Organic Anion Transporters, Sodium-Dependent, Cholestasis, Intrahepatic, PFIC1, Bile Acids and Salts, Feces, Cholestasis, ATP8B1, Internal medicine, medicine, Humans, Intestinal Mucosa, Molecular Biology, Adenosine Triphosphatases, SLC10A2, Symporters, Bile acid, biology, Reverse Transcriptase Polymerase Chain Reaction, Chemistry, Cell Membrane, Progressive familial intrahepatic cholestasis, Membrane Proteins, Biological Transport, Flippase, Apical membrane, medicine.disease, Solute carrier family, Endocrinology, Mutation, biology.protein, Molecular Medicine, RNA Interference, Caco-2 Cells, Protein Multimerization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447770511241fa130db0e309c13b34c2
https://doi.org/10.1016/j.bbadis.2014.09.003

المؤلفون: Valery V. Shevchenko, Robert A. F. M. Chamuleau, R.O. Elferink, Vincent A. van der Mark, D. Rudi de Waart, Ruurdtje Hoekstra

المساهمون: Tytgat Institute for Liver and Intestinal Research, Gastroenterology and Hepatology, Surgery, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism

المصدر: Drug metabolism and disposition: the biological fate of chemicals, 45(1), 56-67. American Society for Pharmacology and Experimental Therapeutics

مصطلحات موضوعية: 0301 basic medicine, CYP2B6, Cellular differentiation, Genetic Vectors, Cell Culture Techniques, Drug Evaluation, Preclinical, Pharmaceutical Science, Receptors, Cytoplasmic and Nuclear, Models, Biological, 03 medical and health sciences, Cell Line, Tumor, Constitutive androstane receptor, Humans, Dimethyl Sulfoxide, Constitutive Androstane Receptor, Pharmacology, biology, CYP3A4, Lentivirus, Cytochrome P450, Cell Differentiation, Metabolic Detoxication, Phase II, Cell biology, Culture Media, 030104 developmental biology, Biochemistry, Nuclear receptor, Liver, Pharmaceutical Preparations, Cell culture, biology.protein, Metabolic Detoxication, Phase I, Drug metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078f707c2a727f04fef563a9dc1dc015
https://pubmed.ncbi.nlm.nih.gov/27780834

المؤلفون: Mina Komuta, Alexey Shiryaev, Anje A. te Velde, Jung-Chin Chang, Johannes R. Hov, Peter L.M. Jansen, Tom H. Karlsen, Shanna Tol, Ulrich Beuers, Serge J. Zweers, Tania Roskams, Maria J. Perugorria, Mette Vesterhus, Jesus M. Banales, D. Rudi de Waart, Frank G. Schaap, Wouter J. de Jonge

المساهمون: Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Other departments, MUMC+: MA Maag Darm Lever (9), RS: NUTRIM - R2 - Gut-liver homeostasis, Surgery, RS: FPN MaCSBio, RS: FHML MaCSBio

المصدر: Liver international, 36(9), 1370-1377. Wiley-Blackwell
Liver International, 36(9), 1370-1377. Wiley

مصطلحات موضوعية: Male, 0301 basic medicine, LIVER, endocrine system diseases, medicine.medical_treatment, HEPATITIS-C, Liver transplantation, Gastroenterology, Pathogenesis, ACTIVATION, 0302 clinical medicine, Medicine, Biliary Tract, gallbladder, Cholangiopancreatography, Endoscopic Retrograde, Norway, digestive, oral, and skin physiology, primary sclerosing cholangitis, Middle Aged, Immunohistochemistry, medicine.anatomical_structure, Female, 030211 gastroenterology & hepatology, Adult, EXPRESSION, medicine.medical_specialty, Cholangitis, Sclerosing, bile, interleukin 8, IMMUNITY, digestive system, Primary sclerosing cholangitis, 03 medical and health sciences, Internal medicine, Humans, RNA, Messenger, Interleukin 8, Aged, Cell Proliferation, Hepatology, IL-8, business.industry, Gallbladder, Interleukin-8, FGF19, medicine.disease, BILIARY EPITHELIAL-CELLS, digestive system diseases, Liver Transplantation, Transplantation, 030104 developmental biology, T-CELLS, Endoscopic retrograde cholangiography, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5753fcb0cafa86757d6ce116dc6ca4a7
https://pure.amc.nl/en/publications/elevated-interleukin8-in-bile-of-patients-with-primary-sclerosing-cholangitis(7e7fbd9a-c922-470c-9c2b-43f644b26a5a).html

المؤلفون: Sander M. Houten, Chiel C. de Theije, Cindy Kunne, D. Rudi de Waart, Wouter H. Lamers, Jan M. Ruijter, Youji He, Hans M.H. van Eijk, S. Eleonore Köhler, W. T. Labruyere, Jacqueline L.M. Vermeulen, Nicolaas E. P. Deutz, Milka Sokolović, Theodorus B. M. Hakvoort, Gabrie A. M. Ten Have

المساهمون: Amsterdam Gastroenterology Endocrinology Metabolism, Tytgat Institute for Liver and Intestinal Research, Paediatric Metabolic Diseases, Laboratory Genetic Metabolic Diseases, Medical Biochemistry, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction & Development (AR&D), Medical Biology, Anatomie & Embryologie, Anatomie en Embryologie, Surgery, RS: NUTRIM - R2 - Gut-liver homeostasis

المصدر: Journal of biological chemistry, 285(13), 9516-9524. American Society for Biochemistry and Molecular Biology Inc.
Journal of Biological Chemistry, 285(13), 9516-9524. American Society for Biochemistry and Molecular Biology, Inc.

مصطلحات موضوعية: Male, EXPRESSION, medicine.medical_specialty, Genotype, Glutamine, Mice, Transgenic, Biology, METABOLISM, Biochemistry, RATS, chemistry.chemical_compound, Mice, Sex Factors, Biosynthesis, Ammonia, Glutamate-Ammonia Ligase, Glutamine synthetase, Internal medicine, PROTEIN BREAKDOWN, medicine, Animals, Urea, AMINO-ACIDS, Muscle, Skeletal, Molecular Biology, Alleles, IN-VIVO, Muscles, Skeletal muscle, Cell Biology, Metabolism, Protein catabolism, METHIONINE-DL-SULFOXIMINE, Endocrinology, medicine.anatomical_structure, chemistry, Ketone bodies, SKELETAL-MUSCLE, Female, ACUTE LIVER-FAILURE, Food Deprivation, WHOLE-BODY

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434e0baeff33fdc530eadfaa1852e152
https://doi.org/10.1074/jbc.m109.092429

المؤلفون: Dineke E. Folmer, Ronald P.J. Oude Elferink, P. M. Hilarius, Arthur J. Verhoeven, Coen C. Paulusma, Kam S. Ho-Mok, D. Rudi de Waart

المساهمون: AII - Amsterdam institute for Infection and Immunity, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Tytgat Institute for Liver and Intestinal Research, Other Research, Graduate School, Landsteiner Laboratory, Gastroenterology and Hepatology

المصدر: Hepatology (Baltimore, Md.), 47(1), 268-278. John Wiley and Sons Ltd

مصطلحات موضوعية: DNA, Complementary, Green Fluorescent Proteins, Molecular Sequence Data, Gene Expression, CHO Cells, Phosphatidylserines, Endoplasmic Reticulum, Cell membrane, chemistry.chemical_compound, Mice, Cricetulus, Cricetinae, medicine, Animals, Humans, Amino Acid Sequence, RNA, Messenger, Antigens, Adenosine Triphosphatases, Hepatology, biology, Endoplasmic reticulum, Cell Membrane, Progressive familial intrahepatic cholestasis, Membrane Proteins, STIM1, Flippase, Phosphatidylserine, medicine.disease, Cell biology, medicine.anatomical_structure, 4-Chloro-7-nitrobenzofurazan, Hemagglutinins, Biochemistry, chemistry, Membrane protein, Liver, Chaperone (protein), biology.protein, Lysosomes, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6653bf624b8b68b60418db170e0f234
https://doi.org/10.1002/hep.21950

المؤلفون: Cindy Kunne, Alan F. Hofmann, Kam S. Ho-Mok, Laura N. Bull, D. Rudi de Waart, Frans J. Hoek, Ludmila Pawlikowska, Kees A. Hoeben, Jan van Marle, Coen C. Paulusma, Heleen Vreeling, A.S. Knisely, A. K. Groen, Astrid L. Spijkerboer, Ronald P.J. Oude Elferink

المساهمون: AII - Amsterdam institute for Infection and Immunity, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Tytgat Institute for Liver and Intestinal Research, Cell Biology and Histology, Gastroenterology and Hepatology

المصدر: Hepatology (Baltimore, Md.), 44(1), 195-204. John Wiley and Sons Ltd

مصطلحات موضوعية: Male, medicine.medical_specialty, ATPase, Blotting, Western, Phospholipid, Cholestasis, Intrahepatic, In Vitro Techniques, digestive system, Bile Acids and Salts, Mice, chemistry.chemical_compound, Liver disease, Cholestasis, Phospholipid transfer protein, Internal medicine, medicine, Animals, Phospholipid Transfer Proteins, Adenosine Triphosphatases, Hepatology, biology, Cholesterol, Bile Canaliculi, Cell Membrane, Progressive familial intrahepatic cholestasis, Biological Transport, Phosphatidylserine, medicine.disease, Immunohistochemistry, Disease Models, Animal, Microscopy, Electron, Endocrinology, chemistry, biology.protein, Chromatography, Thin Layer, Hydrophobic and Hydrophilic Interactions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7419461a29473ad3ea0a79651b2dae
https://doi.org/10.1002/hep.21212