المؤلفون: Kenji Yamatoya, Yuya Nagai, Naozumi Teramoto, Woojin Kang, Kenji Miyado, Kazuya Nakata, Tohru Yagi, Yoshitaka Miyamoto

المصدر: Regenerative Therapy
Regenerative Therapy, Vol 19, Iss, Pp 58-68 (2022)

مصطلحات موضوعية: Medicine (General), SDS, sodium dodecyl sulfate, ESC, embryonic stem cells, Biomedical Engineering, NeuN, a neuronal marker, DMSO, dimethyl sulfoxide, DAPI, 4′,6-Diamidino-2-phenylindole, dihydrochloride, D-PBS-free, Dulbecco's phosphate-buffered saline without Ca2+ and Mg2+ supplementation, Biomaterials, iPSC, induced pluripotent stem cells, R5-920, FBS, fetal bovine serum, Sericin, Cryopreservation, QH573-671, Regenerative therapy, D-MEM, Dulbecco's Modified Eagle's Medium with high glucose, l-glutamine, phenol red, and sodium pyruvate, EDTA, ethylene-diamine-tetraacetic acid, 5-CFDA-AM, 5-carboxyfluorescein diacetate, Differentiation, Neuronal cells, Original Article, BSA, bovine serum albumin, Cytology, Serum-free, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05e5e2da866000a81553e84ac48fa62
https://doi.org/10.1016/j.reth.2021.12.007

المؤلفون: Hitoshi Endo, Takayo Yanagawa, Yosuke Okamura, Junpei Yasuda, Hideaki Sumiyoshi, Akira T. Kawaguchi, Yutaka Inagaki, Sachie Nakao, Tomoko Kubota, Yuki Matsuki

المصدر: Regenerative Therapy
Regenerative Therapy, Vol 18, Iss, Pp 223-230 (2021)

مصطلحات موضوعية: DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride, Medicine (General), Pathology, medicine.medical_specialty, Jellyfish, medicine.medical_treatment, Basic fibroblast growth factor, b-FGF, basic fibroblast growth factor, Biomedical Engineering, Wound healing, Absorption (skin), Jellyfish collagen, Biomaterials, chemistry.chemical_compound, R5-920, External medicine, Dermis, biology.animal, Intractable ulcer, medicine, H-E, hematoxylin-eosin, Saline, QH573-671, integumentary system, Epidermis (botany), biology, medicine.anatomical_structure, chemistry, Original Article, Cytology, Type I collagen, Re-epithelialization, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53818c283f646b241b483c61cb8d4e1
https://doi.org/10.1016/j.reth.2021.06.008

المؤلفون: Po Hu, Hongzheng Wang, Xiaoxuan Yu, Wenzhuo Sun, Hui Hui, Hui Li, Mengyuan Zhu, Zhanyu Wang, Jingyan Xu, Qinglong Guo, Yingjie Qing

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3178-3192 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: NPC, Niemann-Pick type disease C, Cathepsin D, ATG, autophagy related, NH4Cl, ammonium chloride, Lysosomal damage, Calcium in biology, Hematological malignancies, 0302 clinical medicine, RAB7A, RAS-related protein RAB-7a, K48, lysine 48, LC3, microtubule-associated protein 1 light chain 3, TFEB, transcription factor EB, General Pharmacology, Toxicology and Pharmaceutics, 0303 health sciences, RT-qPCR, real time quantitative PCR, Chemistry, LCD, lysosome-dependent cell death, CaN, calcineurin, P62/SQSTM1, sequestosome 1, Cell biology, TRPML1, transient receptor potential mucolipin 1, medicine.anatomical_structure, Cholesterol, 030220 oncology & carcinogenesis, shRNA, short hairpin RNA, Original Article, CsA, cyclosporine A, DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride, Programmed cell death, AO, acridine orange, CTSD, cathepsin D, LW-218, PBS, phosphate-buffered saline, CTSB, cathepsin B, LMP, lysosome membrane permeabilization, EGTA, ethylene glycol-bis(2-aminoethyl ether)-N,N,N′,N′-tetraacetic acid, RM1-950, Lysosome-dependent cell death, 03 medical and health sciences, Dex, dexamethasone, ROS, reactive oxygen species, FBS, fetal bovine serum, Lysosome, NPC1, NPC intracellular cholesterol transporter 1, medicine, BAF A1, bafilomycin A1, 030304 developmental biology, Cathepsin, PBMCs, peripheral blood mononuclear cells, Lysosomal membrane permeabilization, K63, lysine 63, Cell growth, DCFH-DA, 2,7-dichlorodi-hydrofluorescein diacetate, Autophagy, BID, BH3-interacting domain death agonist, Lysophagy, OD, optical density, TFEB, CCK8, Cell Counting Kit, Therapeutics. Pharmacology, LAMPs, lysosomal-associated membrane proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2bc1bb062d92dcf545995a174a1320
http://www.sciencedirect.com/science/article/pii/S2211383521000411

المؤلفون: Young Yun Jung, Jae-Young Um, Kwang Seok Ahn, In Jin Ha, Gautam Sethi

المصدر: Journal of Advanced Research
Journal of Advanced Research, Vol 35, Iss, Pp 245-257 (2022)

مصطلحات موضوعية: 0301 basic medicine, Medicine (General), IHC, Immunohistochemistry, Science (General), FCN, Fangchinoline, STAT3, signal transducer and activator of transcription 3, Pharmaceutical Science, P/S, Penicillin-streptomycin, Apoptosis, Fangchinoline, NT, Non treat, medicine.disease_cause, Stat3 Signaling Pathway, STAT3, Q1-390, Mice, 0302 clinical medicine, Multiple myeloma, Multidisciplinary, SHP-1, Src homology 2 domain-containing protein tyrosine phosphatase-1, biology, Chemistry, Protein Tyrosine Phosphatase, Non-Receptor Type 6, ROS, c/w, Cell per well, VEGF, vascular endothelial growth factor, Cell biology, 030220 oncology & carcinogenesis, JAK, Janus kinase, PARP, Poly (ADP-ribose) polymerase, DMEM, Dulbecco’s Modified Eagle Medium, HRP, Horseradish peroxidase, STAT3 Transcription Factor, Programmed cell death, MMP, Matrix metalloproteinase, Benzylisoquinolines, 03 medical and health sciences, R5-920, RTCA, Real-time cell analysis, medicine, GSH, Animals, Electrophoretic mobility shift assay, ComputingMethodologies_COMPUTERGRAPHICS, GAPDH, Glyceraldehyde 3-phosphate dehydrogenase, Cell growth, RT-PCR, Reverse transcription polymerase chain reaction, ICC, Immunocytochemistry, Oxidative Stress, 030104 developmental biology, ip, Intraperitoneal injection, Tumor progression, DAPI, 4′,6-Diamidino-2-Phenylindole, Dihydrochloride, biology.protein, STAT protein, FBS, Fetal bovine serum, Carcinogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827fdb8a08fdd8e28ed3bcdc4a40ef6f
http://europepmc.org/articles/PMC8721253

المؤلفون: Masahisa, Nozaki, Asako, Otomo, Shun, Mitsui, Suzuka, Ono, Ryohei, Shirakawa, YongPing, Chen, Yutaro, Hama, Kai, Sato, XuePing, Chen, Toshiyasu, Suzuki, Hui-Fang, Shang, Shinji, Hadano

المصدر: eNeurologicalSci

مصطلحات موضوعية: DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride, SDS, sodium dodecyl sulfate, CCCP, carbonyl cyanide 3-chlorophenylhydrazone, CQ, chloroquine, PBS, phosphate-buffered saline, Frontotemporal dementia (FTD), GST, glutathione S-transferase, CI, complete protease inhibitor, PVDF, polyvinylidene difluoride, DMEM, Dulbecco's Modified Eagle's medium, Autophagy, SQSTM1, EBSS, Earle's Balanced Salt Solution, Amyotrophic lateral sclerosis (ALS), MAP1LC3/LC3, PAGE, polyacrylamide gel electrophoresis, IPTG, isopropyl thio-beta-D-galactoside, HRP, horseradish peroxidase, MND, motor neuron disease, ALS, amyotrophic lateral sclerosis, MEF, mouse embryonic fibroblast, WT, wild-type, NGS, normal goat serum, DTT, dithiothreitol, SBMA, spinal and bulbar muscular atrophy, RT, room temperature, Original Article, SQSTM1/p62-body, PFA, paraformaldehyde, HA, hemagglutinin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::0559a3914a18e9cbb7aec0bb21736d3f
https://pubmed.ncbi.nlm.nih.gov/33319079

المؤلفون: Annika Höhn, Jeannette König, Martín Hugo, Tilman Grune, Anne-Laure Bulteau, Tobias Jung, Christiane Ott

المصدر: Redox Biology, Vol 11, Iss, Pp 673-681 (2017)
Redox Biology

مصطلحات موضوعية: Protein aggregates, 0301 basic medicine, Aging, DNP, 2,4-dinitrophenylhydrazone, Protease La, SDHA, Succinate Dehydrogenase Complex Flavoprotein Subunit A, PINK1, PTEN-induced putative kinase 1, SIPS, Stress-induced premature senescence, Clinical Biochemistry, Mitochondrial Degradation, mtDNA, Mitochondrial DNA, shRNA, Short hairpin RNA, Mitochondrion, medicine.disease_cause, Biochemistry, chemistry.chemical_compound, Dox, Doxycycline, Mitophagy, Ex, Excitation wavelength, lcsh:QH301-705.5, Cellular Senescence, lcsh:R5-920, MTT, Methylthiazolyldiphenyl-tetrazolium bromide, Superoxide, MitoTEMPO, (2-(2,2,6,6-Tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl)triphenyl-phosphonium chloride, Fis1, Mitochondrial fission 1 protein, EDTA, Ethylenediaminetetraacetic acid, Mitochondria, RNAi, RNA interference, Mitochondrial fission, COX IV, Cytochrome c oxidase subunit IV, lcsh:Medicine (General), Research Paper, FITC, Fluorescein isothiocyanate, FCCP, Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone, MT-CO1, mitochondrially encoded cytochrome c oxidase I, Oxidative phosphorylation, DMEM, Dulbecco's Modified Eagle Medium, Biology, Lipofuscin, PI, propidium iodide, 03 medical and health sciences, Mdivi-1, Mitochondrial division inhibitor 1, Autophagy, medicine, Animals, Humans, PQ, Paraquat, H2DCFDA, 2',7'-Dichlorodihydrofluorescein diacetate, DAPI, 4′,6-Diamidino-2-phenylindole dihydrochloride, Organic Chemistry, CCCP, Carbonyl cyanide 3-chlorophenylhydrazone, DMSO, Dimethyl sulfoxide, Lon protease, Ki-67, Kiel 67 protein, SA-β-Gal, Senescence associated β-galactosidase, Em, Emission wavelength, SDS, Sodium dodecyl sulfate, DNPH, 2,4-dinitrophenylhydrazine, OCR, Oxygen consumption rate, ETC, Electron transport chain, Oxidative Stress, 030104 developmental biology, lcsh:Biology (General), chemistry, FBS, Fetal bovine serum, MTG, MitoTracker GreenFM, Drp-1, Dynamin-related protein 1, Lysosomes, Reactive Oxygen Species, Oxidative stress, HeLa Cells, ROS, Reactive oxygen species, VDAC, Voltage-dependent anion channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b053b6715c249bddea305f552bc2f1af

المؤلفون: Medha Sharma, Veronique Giroux, Alain Benitez, Kathryn E. Hamilton, Anil K. Rustgi, Joshua Wang, Kelly A. Whelan, Andres J. Klein-Szanto, Jonathan M. Spergel, Hiroshi Nakagawa, Gary W. Falk, Prasanna M. Chandramouleeswaran, John W. Tobias, Amanda B. Muir, Koji Tanaka, Maureen DeMarshall, Yuta Kasagi

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 333-352 (2018)

مصطلحات موضوعية: 0301 basic medicine, Keratinocytes, Cellular differentiation, KSFMC, KSFM containing 0.6 mM Ca2+, TNF-α, tumor necrosis factor-α, IVL, Involucrin, DNMAML1, dominant negative MAML1, KSFM, keratinocyte SFM, GSI, γ-secretase inhibitor, Original Research, GFP, green fluorescent protein, Gastroenterology, Transfection, Phenotype, 3. Good health, aDMEM/F12, advanced Dulbecco's Modified Eagle Medium: Nutrient Mixture F-12, EMT, epithelial-mesenchymal transition, IHC, immunohistochemistry, MAML1, Mastermind-like protein1, DOX, doxycycline, Notch signaling pathway, Context (language use), 03 medical and health sciences, 3D, 3-dimensional, medicine, Organoid, Squamous Cell Differentiation, GERD, gastroesophageal reflux disease, IF, immunofluorescence, EoE, eosinophilic esophagitis, lcsh:RC799-869, Tslp, thymic stromal lymphopoietin, Eosinophilic esophagitis, EGF, epidermal growth factor, Hepatology, Esophageal disease, business.industry, Eosinophilic Esophagitis, medicine.disease, qRT-PCR, quantitative reverse-transcription polymerase chain reaction, IL, interleukin, BCH, basal cell hyperplasia, 030104 developmental biology, Three-Dimensional, DAPI, 4′,6-Diamidino-2-Phenylindole, Dihydrochloride, Cancer research, H&E, hematoxylin and eosin, lcsh:Diseases of the digestive system. Gastroenterology, OFR, organoid formation rate, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf559d5921b9cf26542c0bccc5572c3
https://pubmed.ncbi.nlm.nih.gov/29552622

المؤلفون: Tewari, Rajesh Kumar, Hadacek, Franz, Sassmann, Stefan, Lang, Ingeborg

المصدر: Environmental and Experimental Botany

مصطلحات موضوعية: DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride, Deprivation, Iron, DHA, dehydroascorbic acid, Plant Science, Y(II), effective quantum yield, Article, SOD, superoxide dismutase, TBARS, thiobarbituric acid reactive substances, PCD, programmed cell death, DNAse, deoxyribonuclease, Brassica napus, Caspase, Deficiency, Programmed cell death, Reactive oxygen species, DTT, 1,4-dithio-dl-threitol, Ecology, Evolution, Behavior and Systematics, DAB, 3,3′-diaminobenzidine, EDTA, ethylenediaminetetraacetic acid, NBT, p-nitro-blue tetrazolium chloride, ETR, electron transport rate, food and beverages, POD, peroxidase, APX, ascorbate peroxidase, AA, ascorbic acid, CAT, catalase, Agronomy and Crop Science, ETS, electron transport system

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5d9a8f99b2e941381de5ce265779f80f

المؤلفون: Larry H. Matherly, Zhanjun Hou, Steve Orr

المصدر: Bioscience Reports
Bioscience Reports, Vol 34, Iss 4, p e00130 (2014)

مصطلحات موضوعية: TMQ, trimetrexate (2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline, PDI, protein disulfide isomerase, lcsh:Life, lcsh:QR1-502, DSS, disuccinimidyl suberate, PCFT, proton-coupled folate transporter, Endoplasmic Reticulum, Biochemistry, lcsh:Microbiology, Reduced Folate Carrier Protein, dg, deglycosylated, Pmx, pemetrexed, RNA Processing, Post-Transcriptional, Promoter Regions, Genetic, Regulation of gene expression, sulfo-NHS-SS-biotin, sulfo-N-hydroxysuccinimide-SS-biotin, Membrane transport protein, DAPI, 4′,6-diamidino-2-phenylindole, dihydrochloride, Transfection, Mtx, methotrexate, Cell biology, UTR, untranslated region, transporter, hRFC, human RFC, hGAPDH, human glyceraldehyde-3-phosphate dehydrogenase, LCV, (6R,S)5-formyl tetrahydrofolate (leucovorin), Intracellular, wt, wild-type, Biophysics, Methotrexate transport, Biology, Folic Acid Deficiency, folate, S5, oligomerization, antifolate, ER, endoplasmic reticulum, Folic Acid, Cell Line, Tumor, Extracellular, Humans, reduced folate carrier, Molecular Biology, Original Paper, Endoplasmic reticulum, Cell Membrane, FR, folate receptor, Membrane Transport Proteins, Biological Transport, Cell Biology, lcsh:QH501-531, RFC, reduced folate carrier, Membrane protein, Gene Expression Regulation, biology.protein, post-transcriptional regulation, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce224761b93f1a493f46dbb42e85a71
http://europepmc.org/articles/PMC4122975

المؤلفون: Preeti Subramanian, Defen Shen, Jingsheng Tuo, Yujuan Wang, Chi-Chao Chan, S. Patricia Becerra

المصدر: ASN NEURO
ASN Neuro, Vol 5 (2013)

مصطلحات موضوعية: Retinal degeneration, retina, IL-17a, interleukin-17a, genetic structures, Anti-Inflammatory Agents, ONL, outer nuclear layer, Apoptosis, Pyridinium Compounds, rd, retinal degeneration, chemistry.chemical_compound, Mice, AMD, age-related macular degeneration, Cells, Cultured, Chemokine CCL2, iNos, inducible nitric oxide synthase, PEDF, pigment epithelium-derived factor, General Neuroscience, Retinal Degeneration, INL, inner nuclear layer, medicine.anatomical_structure, DKO rd8, Ccl2−/−/Cx3cr1−/− on C57BL/6N [Crb1rd8], Cytokines, Receptors, Chemokine, neuroprotection, Research Article, DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride, medicine.medical_specialty, Programmed cell death, pigment epithelium-derived factor, RPE, retinal pigment epithelium, OPL, outer plexiform layer, CX3C Chemokine Receptor 1, Mice, Transgenic, Nerve Tissue Proteins, S6, Biology, qRT-PCR, quantitative reverse transcription-PCR, S3, CNS, central nervous system, TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling, lcsh:RC321-571, Retinoids, DMEM/F12, Dulbecco’s modified Eagle’s medium: Ham’s nutrient mixture F-12, PEDF, VEGFA, vascular endothelial growth factor A, Internal medicine, medicine, Animals, Humans, Nerve Growth Factors, Eye Proteins, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, age-related macular degeneration, Serpins, CNV, choroidal neovascularization, Retina, Retinal pigment epithelium, IL-1β, interleukin-1 beta, TNFα, tumor necrosis factor-alpha, IS/OS, inner/outer segment, Retinal, Epithelial Cells, Macular degeneration, medicine.disease, WT, wild-type, eye diseases, Mice, Inbred C57BL, Disease Models, Animal, FasL, Fas ligand, Endocrinology, Nerve growth factor, chemistry, Gene Expression Regulation, inflammation, Immunology, Mutation, A2E, [2,6-dimethyl-8-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1E,3E,5E,7E-octatetra-enyl]-1-(2-hydroxyethyl)-4-[4-methyl-6(2,6,6-trimethyl-1-cyclohexen1-yl) 1E,3E,5E,7E-hexatrienyl]-pyridinium, Neurology (clinical), sense organs, Crb1, crumbs-like 1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1c7ff16467784a749bcd583427cec6
https://pubmed.ncbi.nlm.nih.gov/24160756