المؤلفون: Sriganesh Ramachandra Rao, Steven J. Fliesler

المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100057-(2021)
Journal of Lipid Research

مصطلحات موضوعية: 0301 basic medicine, retina, 7DHC, 7-dehydrocholesterol, retinal pigment epithelium, SRB-I/II, class B scavenger receptor (I and II), GCL, Ganglion cell layer, 030204 cardiovascular system & hematology, A2E, N-Retinylidene-N-retinylethanolamine (2-[2,6-dimethyl-8-(2,6,6-trimethyl-1-cyclohexen-1- yl)-1E,3E, 5E,7E-octatetraenyl]-1-(2-hydroxyethyl)-4-[4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1E, 3E, 5E-hexatrienyl]-pyridinium), IS, inner segment, Biochemistry, 0302 clinical medicine, Endocrinology, homeostasis, AMD, age-related macular degeneration, ERG, electroretinogram, HMGCR, HMG-CoA reductase, DHCR24, 24-dehydrocholesterol reductase, SQLE, squalene monooxygenase, biology, lipoprotein, LAL, lysosomal acid lipase, MVK, mevalonate kinase, Sterol transport, LRP1, VEGF, vascular endothelial growth factor, Cell biology, OS, outer segment(s), medicine.anatomical_structure, HMG-CoA reductase, lipids (amino acids, peptides, and proteins), oxysterol, iPSC, induced pluripotent stem cell, RPE, retinal pigment epithelium, Oxysterol, TSPO, translocator protein 18 kDa, LOX-1, OxLDL receptor, QD415-436, de novo synthesis, CD36, cluster of differentiation 36, DHCR7, 7-dehydrocholesterol reductase, 03 medical and health sciences, medicine, Ganglion cell layer, CNV, choroidal neovascularization, LRP1, LDL-related particle 1, Retina, Retinal pigment epithelium, ROS, reactive oxgen species, cholesterol, Thematic Review Series, Cell Biology, PN, postnatal, photoreceptor, Sterol, eye diseases, NPC-I/II, Niemann-Pick type C I and II, 030104 developmental biology, biology.protein, sense organs, PFO, perfringolysin O

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2dcce4a734ce3a62d7d8b9e37cee54a
http://www.sciencedirect.com/science/article/pii/S0022227521000390

المؤلفون: Wei Liu, Phillip A. Wages, Zeljka Korade, Keri A. Tallman, Hye-Young H. Kim, Ned A. Porter, Thiago C. Genaro-Mattos

المصدر: Redox Biology, Vol 12, Iss, Pp 182-190 (2017)
Redox Biology

مصطلحات موضوعية: 0301 basic medicine, Proteome, Clinical Biochemistry, 7-DHC, 7-dehydrocholesterol, medicine.disease_cause, Biochemistry, Mice, 7-Dehydrocholesterol, chemistry.chemical_compound, Alkynyl sterols, 0302 clinical medicine, Biotin, 7-dehydrocholesterol, lcsh:QH301-705.5, lcsh:R5-920, Chol, cholesterol, APCI, atmospheric pressure chemical ionization, Lanosterol, HPLC-MS, 3. Good health, Sterols, Cholesterol, Lan, lanosterol, lipids (amino acids, peptides, and proteins), GC-MS, lcsh:Medicine (General), Research Paper, Oxidoreductases Acting on CH-CH Group Donors, endocrine system, DMSO, dimethylsulfoxide, DMEM, Dulbecco's Modified Eagle Medium, Models, Biological, DHCR7, 7-dehydrocholesterol reductase, Cell Line, Adduct, 03 medical and health sciences, FBS, fetal bovine serum, PBS, phosphate buffered saline, medicine, Animals, Humans, Lath, lathosterol, NMR, nuclear magnetic resonance, HPLC-, high pressure liquid chromatography, Organic Chemistry, Fibroblasts, medicine.disease, Sterol, Smith-Lemli-Opitz Syndrome, 030104 developmental biology, MS, mass spectrometry, chemistry, lcsh:Biology (General), Smith–Lemli–Opitz syndrome, DHCR7, SLOS, Smith-Lemli-Opitz syndrome, Lipid Peroxidation, MeOH, methanol, 030217 neurology & neurosurgery, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22201128ecf566b5f95b977c40da42a5
http://www.sciencedirect.com/science/article/pii/S2213231717300216

المؤلفون: Raphaela, Kübeck, Catalina, Bonet-Ripoll, Christina, Hoffmann, Alesia, Walker, Veronika Maria, Müller, Valentina Luise, Schüppel, Ilias, Lagkouvardos, Birgit, Scholz, Karl-Heinz, Engel, Hannelore, Daniel, Philippe, Schmitt-Kopplin, Dirk, Haller, Thomas, Clavel, Martin, Klingenspor

المصدر: Molecular Metabolism, Vol 5, Iss 12, Pp 1162-1174 (2016)
Mol. Metab. 5, 1162-1174 (2016)
Molecular Metabolism

مصطلحات موضوعية: Male, Diet-induced obesity resistance, Hsp90, heat shock protein 90, CIDEA, cell death inducing DFFA-like effector, COX4, cytochrome c oxidase subunit 4, BMR, basal metabolic rate, Cyp27a1, cholesterol 27 alpha-hydroxylase, Cholesterol, Dietary, Hprt1, hypoxanthine guanine phosphoribosyl transferase, Mice, DEE, daily energy expenditure, GF, germfree, MCA, muricholic acid, qPCR, quantitative real-time polymerase chain reaction, ANOVA, analysis of variance, Eef2, eukaryotic elongation factor 2, CA, cholic acid, PHFD, high-fat diet based on palm oil, Dhcr7, 7-dehydrocholesterol reductase, Hmgcr, 3-hydroxy-3-methylglutaryl Coenzyme A reductase, Cyp7a1, cholesterol 7 alpha-hydroxylase, Abcg8, ATP-binding cassette sub-family G member 8, HP, heat production, Tf2b, transcription factor II B, Cholesterol, High-fat diet, Adipose Tissue, Liver, Abcg5, ATP-binding cassette sub-family G member 5, Original Article, CD, control diet, Akr1d1, aldo-keto-reductase family member 1, PRDM16, PR domain containing 16, LHFD, high-fat diet based on lard, lcsh:Internal medicine, Hsd11b1, hydroxysteroid (11-β) dehydrogenase 1, TCA, taurocholic acid, Srebf1, sterol regulatory element binding transcription factor 1, Energy balance, Ldlr, low density lipoprotein receptor, Diet, High-Fat, digestive system, SPF, specific pathogen free, GUSB, beta-glucuronidase, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, Nr1h2, nuclear receptor subfamily 1, group H, member 2 (liver X receptor β), UCP1, uncoupling protein 1, Animals, UPLC-TOF-MS, ultraperformance liquid chromatography-time of flight-mass spectrometry, Obesity, Germfree, FT-IR, Fourier transform-infrared spectroscopy, lcsh:RC31-1245, Nr1h3, nuclear receptor subfamily 1, group H, member 3 (liver X receptor α), TMCA, Tauromuricholic acid, Diet-induced Obesity Resistance, Energy Balance, High-fat Diet, DIO, diet-induced obesity, Lipid Metabolism, Dietary Fats, Gastrointestinal Microbiome, Mice, Inbred C57BL, Hmgcs, 3-hydroxy-3-methylglutaryl Coenzyme A synthase 1, DCA, deoxycholic acid, Actb, beta actin, FT-ICR-MS, Fourier transform-Ion Cyclotron Resonance-Mass Spectrometry, HDCA, hyodeoxycholic acid, Nr1h4, nuclear receptor subfamily 1, group H, member 4 (farnesoid X receptor α)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5a00bbb6cef6244342d251ff4ccfc007
http://www.sciencedirect.com/science/article/pii/S2212877816301892

المؤلفون: Michael J. Naldrett, Cole P. Frisbie, Carol A. Casey, Vikas Kumar, Terrence M. Donohue, Nicholas T. Woods, Mark A. McNiven, Paul G. Thomes, Jacy L. Kubik

المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100049-(2021)
Journal of Lipid Research

مصطلحات موضوعية: 0301 basic medicine, lipid droplet, 030204 cardiovascular system & hematology, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Lipid droplet, steatosis, ACSM5, acyl-coenzyme A synthetase 5, HSD17β7, hydroxysteroid 17β-dehydrogenase 7, TFEB, transcription factor EB, PLIN, perilipin, LAL, lysosomal acid lipase, perilipins, Cell biology, mitochondria, TE, Tris/EDTA, WB, Western blot, ACSM1, acyl-coenzyme A synthetase 1, immunohistochemistry, G0s2, G0/G1 switch protein 2, Proteome, Research Article, FDR, false discovery rate, LD, lipid droplet, fasting, CIDEB, cell death–inducing DFFA-like effector B, Phospholipid, LAMP, lysosome-associated membrane protein, QD415-436, pATGL, phosphorylated adipocyte TG lipase, liver, DHCR7, 7-dehydrocholesterol reductase, 03 medical and health sciences, proteomics, HSC70, heat shock cognate protein 70, Lipid biosynthesis, COXIV, cytochrome c oxidase subunit IV, medicine, LSS, lanosterol synthase, HSD17β11, hydroxysteroid 17β-dehydrogenase 11, ATP6V0A1, ATPase 116 kDa subunit a isoform 1, Ethanol, HSD17β13, hydroxysteroid 17β-dehydrogenase 13, PCA, principal component analyses, Lipid metabolism, Lipid Droplets, MS, Cell Biology, IPA, ingenuity pathway analysis, medicine.disease, pHSL, phosphorylated hormone-sensitive lipase, 030104 developmental biology, TM7SF2, delta (14)-sterol reductase, chemistry, Membrane protein, Perilipin, Steatosis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6b72afdd6d08e0189d10784f5843e3c
https://doi.org/10.1016/j.jlr.2021.100049

المؤلفون: Bertoccini, Laura, Bailetti, Diego, SUMMER Study in Diabetes Group (Summer, Alessi, Elena, Bagella, FRANCESCO MARIA, Barchetta, Ilaria, Capoccia, Danila, Silvia, Carletti, Coccia, Federica, Conti, Francesco, D'Onofrio, Luca, Filardi, Tiziana, Giulia, Leanza, Gianluca, Margiotta, Incani, Michela, Moretti, Chiara, Pezzilli, Serena, Pibiri, Carlotta, Pamela, Piscitelli, Maria Giovanna Scarale, Sentinelli, Federica, Tavaglione, Federica, Buzzetti, Raffaella, Cavallo, Maria Gisella, Copetti, Massimiliano, Cossu, Efisio, D'Angelo, Paola, De Cosmo, Salvatore, Di Mauro, Lazzaro, Leonetti, Frida, Morano, Susanna, Morviducci, Lelio, Napoli, Nicola, Prudente, Sabrina, Pugliese, Giuseppe, Trischitta, Vincenzo, Baroni Marco, Giorgio.

المساهمون: Bertoccini, L., Bailetti, D., Buzzetti, R., Cavallo, M. G., Copetti, M., Cossu, E., D'Angelo, P., De Cosmo, S., Di Mauro, L., Leonetti, F., Morano, S., Morviducci, L., Napoli, N., Prudente, S., Pugliese, G., Trischitta, V., Baroni, M. G., Alessi, E., Bagella, F., Barchetta, I., Capoccia, D., Carletti, S., Coccia, F., Conti, F., D'Onofrio, L., Filardi, T., Leanza, G., Margiotta, G., Incani, M., Moretti, C., Pezzilli, S., Pibiri, C., Piscitelli, P., Scarale, M. G., Sentinelli, F., Tavaglione, F.

المصدر: Scopus-Elsevier
Oncotarget

مصطلحات موضوعية: medicine.medical_specialty, Population, Type 2 diabetes, 030204 cardiovascular system & hematology, genetic risk score, 03 medical and health sciences, 0302 clinical medicine, Diabetes mellitus, Internal medicine, Genotype, medicine, Vitamin D and neurology, 030212 general & internal medicine, education, Gene, education.field_of_study, Framingham Risk Score, CYP2R1 (Cytochrome P450 Family 2 Subfamily R Member 1), business.industry, GC (Vitamin D Binding Protein), Mortality rate, DHCR7 (7-dehydrocholesterol reductase), medicine.disease, Genetic risk score, Endocrinology, Oncology, SUMMER Study in Diabetes, business, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4503b0772d3da0b46daeb840ef79eb0e
http://hdl.handle.net/11697/143142

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المؤلفون: Kübeck R; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Molecular Nutritional Medicine, Technical University of Munich, TUM School of Life Sciences Weihenstephan, EKFZ - Else Kröner-Fresenius-Center for Nutritional Medicine, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Bonet-Ripoll C; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Molecular Nutritional Medicine, Technical University of Munich, TUM School of Life Sciences Weihenstephan, EKFZ - Else Kröner-Fresenius-Center for Nutritional Medicine, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Hoffmann C; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Molecular Nutritional Medicine, Technical University of Munich, TUM School of Life Sciences Weihenstephan, EKFZ - Else Kröner-Fresenius-Center for Nutritional Medicine, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Walker A; Research Unit Analytical BioGeoChemistry, Department of Environmental Sciences, Helmholtz Zentrum München, Ingolstädter Landstr.1, 85764 Neuherberg, Germany., Müller VM; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Nutritional Physiology, Technical University of Munich, TUM School of Life Sciences Weihenstephan, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Schüppel VL; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Nutrition and Immunology, Technical University of Munich, TUM School of Life Sciences Weihenstephan, Maximus-von-Imhof-Forum 2, 85354 Freising, Germany., Lagkouvardos I; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Scholz B; Chair of General Food Technology, Technische Universität München, Alte Akademie 10, 85354 Freising, Germany., Engel KH; Chair of General Food Technology, Technische Universität München, Alte Akademie 10, 85354 Freising, Germany., Daniel H; Chair of Nutritional Physiology, Technical University of Munich, TUM School of Life Sciences Weihenstephan, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Schmitt-Kopplin P; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Research Unit Analytical BioGeoChemistry, Department of Environmental Sciences, Helmholtz Zentrum München, Ingolstädter Landstr.1, 85764 Neuherberg, Germany; Chair of Analytical Food Chemistry, Technische Universität München, Alte Akademie 10, 85354 Freising, Germany., Haller D; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Nutrition and Immunology, Technical University of Munich, TUM School of Life Sciences Weihenstephan, Maximus-von-Imhof-Forum 2, 85354 Freising, Germany., Clavel T; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Klingenspor M; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Molecular Nutritional Medicine, Technical University of Munich, TUM School of Life Sciences Weihenstephan, EKFZ - Else Kröner-Fresenius-Center for Nutritional Medicine, Gregor-Mendel-Str. 2, 85354 Freising, Germany. Electronic address: mk@tum.de.

المصدر: Molecular metabolism [Mol Metab] 2016 Oct 13; Vol. 5 (12), pp. 1162-1174. Date of Electronic Publication: 2016 Oct 13 (Print Publication: 2016).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: eCollection Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Dietary Fats/*adverse effects , Gastrointestinal Microbiome/*physiology , Obesity/*metabolism, Adipose Tissue/metabolism ; Animals ; Cholesterol/metabolism ; Cholesterol, Dietary/metabolism ; Diet, High-Fat/adverse effects ; Dietary Fats/metabolism ; Lipid Metabolism/genetics ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL