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المؤلفون: Alessandro Tancredi, Olga Gusyatiner, Pierre Bady, Michelle C. Buri, Rémy Lomazzi, Davide Chiesi, Mahmoud Messerer, Monika E. Hegi
المصدر: Cell death & disease, vol. 13, no. 12, pp. 1037
مصطلحات موضوعية: Humans, Temozolomide/pharmacology, Temozolomide/therapeutic use, Glioblastoma/drug therapy, Glioblastoma/genetics, Glioblastoma/pathology, Dacarbazine/pharmacology, Dacarbazine/therapeutic use, Nuclear Proteins/metabolism, Antineoplastic Agents, Alkylating/pharmacology, DNA Methylation/genetics, Cell Line, Tumor, Gene Expression Regulation, Neoplastic, Transcription Factors/metabolism, DNA Modification Methylases/genetics, DNA Modification Methylases/metabolism, O(6)-Methylguanine-DNA Methyltransferase/genetics, O(6)-Methylguanine-DNA Methyltransferase/metabolism, O(6)-Methylguanine-DNA Methyltransferase/therapeutic use, DNA Repair Enzymes/genetics, DNA Repair Enzymes/metabolism, DNA/metabolism, Cell Cycle Proteins/metabolism, Cancer Research, Immunology, Nuclear Proteins, Cell Cycle Proteins, DNA, Cell Biology, DNA Methylation, Dacarbazine, O(6)-Methylguanine-DNA Methyltransferase, Cellular and Molecular Neuroscience, DNA Repair Enzymes, Temozolomide, Glioblastoma, Antineoplastic Agents, Alkylating, DNA Modification Methylases, Transcription Factors
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e8b827f62edf473e57c259b29df8a9
https://doi.org/10.21203/rs.3.rs-1832996/v1 -
2رسالة جامعية
المؤلفون: Tumlin Ekelund, Susanne
مصطلحات موضوعية: Colorectal Neoplasms -- genetics, Colorectal Neoplasms -- mortality, Colorectal Neoplasms -- surgery, Neoplasm Staging, DNA Modification Methylases -- genetics, DNA Repair Enzymes -- genetics, Tumor Suppressor Proteins -- genetics, DNA Mutational Analysis -- methods, Loss of Heterozygosity -- genetics, MicroRNAs -- genetics, Tumor Markers, Biological, Lymphatic Metastasis, Gene Regulation Expression, Neoplastic
URL الوصول: http://hdl.handle.net/10616/40824
Degree: Diss. (sammanfattning) Stockholm : Karolinska institutet, 2011
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المؤلفون: Brian Thiessen, Olivier Chinot, Martin J B Taphoorn, Frédéric Dhermain, Jaap C. Reijneveld, Anja Gijtenbeek, Andreas von Deimling, Martin J. van den Bent, Roelien H. Enting, Elodie Vauleon, Alba A. Brandes, Monika E. Hegi, Sebastian Kurscheid, Pierre Bady, Brigitta G. Baumert, Mauro Delorenzi, Roger Stupp, Wolfgang Wick, Pim J. French, Thierry Gorlia, Khê Hoang-Xuan, Christine Marosi
المساهمون: Neurology, CCA - Cancer biology and immunology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy
المصدر: Acta Neuropathologica, 135(4), 601-615
Acta Neuropathologica, 135, 4, pp. 601-615
Acta Neuropathologica, 135(4), 601-615. Springer Verlag
Acta Neuropathologica, 135, 601-615
Acta Neuropathologica, 135(4), 601-615. SPRINGER
Bady, P, Kurscheid, S, Delorenzi, M, Gorlia, T, van den Bent, M J, Hoang-Xuan, K, Vauléon, É, Gijtenbeek, A, Enting, R, Thiessen, B, Chinot, O, Dhermain, F, Brandes, A A, Reijneveld, J C, Marosi, C, Taphoorn, M J B, Wick, W, von Deimling, A, French, P, Stupp, R, Baumert, B G & Hegi, M E 2018, ' The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033 ', Acta Neuropathologica, vol. 135, no. 4, pp. 601-615 . https://doi.org/10.1007/s00401-018-1810-6
Acta Neuropathologica, 135(4), 601-615. Springer, Cham
Acta neuropathologica, vol. 135, no. 4, pp. 601-615
Acta Neuropathologica, 135(4), 601-615. Springer-Verlagمصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Epigenesis, Genetic, MISMATCH REPAIR, 0302 clinical medicine, Promoter Regions, Genetic, DNA Modification Methylases, DNA methylation, Brain Neoplasms, METHYLATION, TEMOZOLOMIDE, Glioma, Methylation, TUMORS, Isocitrate Dehydrogenase, Progression-Free Survival, 3. Good health, Treatment Outcome, Isocitrate dehydrogenase, CpG site, 030220 oncology & carcinogenesis, Female, DNA mismatch repair, Adult, Antineoplastic Agents, Alkylating/therapeutic use, Brain Neoplasms/genetics, Brain Neoplasms/pathology, Brain Neoplasms/therapy, CpG Islands, DNA, DNA Methylation/drug effects, DNA Methylation/radiation effects, DNA Modification Methylases/genetics, DNA Repair Enzymes/genetics, Discoidin Domain Receptors/genetics, Glioma/genetics, Glioma/pathology, Glioma/therapy, Humans, Isocitrate Dehydrogenase/genetics, Neoplasm Grading, Temozolomide/therapeutic use, Tumor Suppressor Proteins/genetics, DDR genes, Low-grade glioma, MGMT-STP27, Randomized trial, TMZ, SENSITIVITY, MGMT, medicine.drug, RADIOTHERAPY, EXPRESSION, medicine.medical_specialty, GLIOBLASTOMA, Other Research Donders Center for Medical Neuroscience [Radboudumc 0], Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, All institutes and research themes of the Radboud University Medical Center, Internal medicine, medicine, Progression-free survival, Antineoplastic Agents, Alkylating, Discoidin Domain Receptors, neoplasms, Temozolomide, business.industry, Tumor Suppressor Proteins, medicine.disease, DNA Repair Enzymes, 030104 developmental biology, CELLS, Neurology (clinical), business
وصف الملف: application/pdf
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المؤلفون: L. Burt Nabors, Thierry Gorlia, J. Straub, Olivier Chinot, Els Genbrugge, Monika E. Hegi, Mark R. Gilbert, Greg Jones, Wim Van Criekinge, Roger Stupp, Michael Weller
المساهمون: University of Zurich, Hegi, Monika E
المصدر: Clin Cancer Res
Clinical cancer research, vol. 25, no. 6, pp. 1809-1816مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Bevacizumab, 610 Medicine & health, Article, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Internal medicine, medicine, Cutoff, 1306 Cancer Research, Temozolomide, Receiver operating characteristic, business.industry, Standard treatment, Antineoplastic Agents, Alkylating/pharmacology, Antineoplastic Agents, Alkylating/therapeutic use, Brain Neoplasms/drug therapy, Brain Neoplasms/genetics, Clinical Trials as Topic, DNA Methylation, DNA Modification Methylases/genetics, DNA Repair Enzymes/genetics, Datasets as Topic, Drug Resistance, Neoplasm/genetics, Female, Glioblastoma/drug therapy, Glioblastoma/genetics, Humans, Male, Middle Aged, Patient Selection, Promoter Regions, Genetic/genetics, Reference Values, Temozolomide/pharmacology, Temozolomide/therapeutic use, Tumor Suppressor Proteins/genetics, 10040 Clinic for Neurology, Clinical trial, 030220 oncology & carcinogenesis, DNA methylation, 2730 Oncology, business, 030217 neurology & neurosurgery, medicine.drug
وصف الملف: Hegi_MGMT.pdf - application/pdf; application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541f2a7bb7145dd80385e963d15f4466
https://www.zora.uzh.ch/id/eprint/161075/ -
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المؤلفون: Michael Platten, G. Pesce, Thierry Gorlia, Kirsten Hopkins, Vassilis Golfinopoulos, Markus Kosch, Wolfgang Wick, Jean-Sebastien Frenel, Christine Marosi, Jonathan Steuve, Michael Weller, Mario Campone, Martin J. van den Bent, Antje Wick, Benoit Lhermitte, Salvador Villà, Krisztian Homicsko, Astrid Weyerbrock, Monika E. Hegi, Pierre Bady, Marie-France Hamou, Damien Ricard, Patrick Roth, Alba A. Brandes, Martin J.B. Taphoorn, Roger Stupp
المساهمون: Neurology, University of Zurich, Wick, Wolfgang
المصدر: Clinical Cancer Research, 22(19), 4797-4806. American Association for Cancer Research Inc.
Clinical Cancer Research, 22(19), 4797-4806
Clinical Cancer Research
Clinical cancer research, vol. 22, no. 19, pp. 4797-4806مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Phases of clinical research, Kaplan-Meier Estimate, 0302 clinical medicine, 1306 Cancer Research, Promoter Regions, Genetic, DNA Modification Methylases, education.field_of_study, Brain Neoplasms, Chemoradiotherapy, Middle Aged, Temsirolimus, 3. Good health, Dacarbazine, 030220 oncology & carcinogenesis, 2730 Oncology, Female, medicine.drug, Adult, medicine.medical_specialty, Population, 610 Medicine & health, 03 medical and health sciences, Young Adult, Internal medicine, medicine, Temozolomide, Humans, education, Aged, Proportional Hazards Models, Brain Neoplasms/drug therapy, Brain Neoplasms/mortality, Brain Neoplasms/radiotherapy, Chemoradiotherapy/methods, DNA Methylation, DNA Modification Methylases/genetics, DNA Repair Enzymes/genetics, Dacarbazine/administration & dosage, Dacarbazine/analogs & derivatives, Glioblastoma/drug therapy, Glioblastoma/mortality, Glioblastoma/radiotherapy, Promoter Regions, Genetic/genetics, Sirolimus/administration & dosage, Sirolimus/analogs & derivatives, Tumor Suppressor Proteins/genetics, Sirolimus, Performance status, business.industry, Tumor Suppressor Proteins, Surgery, 10040 Clinic for Neurology, 030104 developmental biology, DNA Repair Enzymes, 10032 Clinic for Oncology and Hematology, MGMT-Unmethylated Glioblastoma, business, Glioblastoma
وصف الملف: 1078-0432.CCR-15-3153.full.pdf - application/pdf; application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d7fef0d1608d3697456d8fd4775b80
https://doi.org/10.1158/1078-0432.ccr-15-3153 -
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المؤلفون: Hegi, M.E., Stupp, R.
المصدر: Neuro-oncology, vol. 17, no. 11, pp. 1425-1427
مصطلحات موضوعية: Dacarbazine, DNA Repair Enzymes, Brain Neoplasms, Tumor Suppressor Proteins, Editorials, Temozolomide, Humans, Antineoplastic Agents, DNA Methylation, Glioblastoma, Promoter Regions, Genetic, DNA Modification Methylases, Antineoplastic Agents/therapeutic use, Brain Neoplasms/drug therapy, Brain Neoplasms/genetics, DNA Methylation/genetics, DNA Modification Methylases/genetics, DNA Repair Enzymes/genetics, Dacarbazine/analogs & derivatives, Dacarbazine/therapeutic use, Glioblastoma/drug therapy, Glioblastoma/genetics, Promoter Regions, Genetic/genetics, Tumor Suppressor Proteins/genetics
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b2f5b33f538725853901c05af2d50363
https://europepmc.org/articles/PMC4648310/ -
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المؤلفون: Skoglund, A., Bjorkholm, B., Nilsson, C., Andersson, Anders F., Jernberg, C., Schirwitz, K., Enroth, C., Krabbe, M., Engstrand, L.
المصدر: Journal of Bacteriology. 189(24):8914-8921
مصطلحات موضوعية: Cell Line, Cloning, Molecular, DNA Modification Methylases/*genetics/*metabolism, DNA Restriction Enzymes/metabolism, DNA, Bacterial/metabolism, Epithelial Cells/microbiology, Escherichia coli/genetics, Gene Deletion, Gene Expression, Gene Expression Regulation, Bacterial, Helicobacter pylori/*enzymology/*genetics, Humans, Interleukin-8/biosynthesis, Microbial Viability, Mutagenesis, Insertional, Protein Binding, Recombinant Proteins/genetics/isolation & purifica
وصف الملف: print
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مصطلحات موضوعية: Adenocarcinoma/*genetics/pathology, Adenocarcinoma of Lung, Adult, Carcinoma, Non-Small-Cell Lung/*genetics/pathology, Carcinoma, Squamous Cell/*genetics/pathology, DNA Methylation/*genetics, DNA Modification Methylases/*genetics/metabolism, DNA Repair Enzymes/*genetics/metabolism, Female, Humans, Lung Neoplasms/*genetics/pathology, Male, Middle Aged, Promoter Regions, Genetic/*genetics, Tumor Suppressor Proteins/*genetics/metabolism, neoplasms, respiratory tract diseases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3566::9af3ea8378f4cb0d878a325236dcd9ea
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المؤلفون: Psofaki, V., Kalogera, C., Tzambouras, N., Stephanou, D., Tsianos, E., Seferiadis, K., Kolios, G.
مصطلحات موضوعية: Male, Adaptor Proteins, Signal Transducing/*genetics, Colorectal Neoplasms/*genetics/physiopathology, Promoter Regions, Genetic/*genetics, Microsatellite Repeats/genetics, Adenoma/*genetics/physiopathology, Middle Aged, CpG Islands/genetics, Tumor Suppressor Proteins/*genetics, Cyclin-Dependent Kinase Inhibitor p16/*genetics, DNA Methylation/*physiology, Disease Progression, Nuclear Proteins/*genetics, DNA Modification Methylases/*genetics, Humans, Female, DNA Repair Enzymes/*genetics, Aged
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_____10561::63785f386222efb9cf690443a8539e8c
http://olympias.lib.uoi.gr/jspui/handle/123456789/18981 -
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المؤلفون: Pierre Levillain, C.J. Larsen, Lucie Karayan-Tapon, Joelle Guilhot, Philippe Rigoard, Philippe Menei, Serge Milin, J.-L. Blanc, F. Duthe, B. Bataille, F. Lapierre, Dominique Bonneau, Sophie Michalak, Michel Wager
المساهمون: Micro et Nanomédecines Biomimétiques (MINT), Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Bretagne Loire (UBL), Centre Scientifique et Technique du Bâtiment (CSTB), Unité d'épidémiologie, biostatistique et registre des cancers [Poitou-Charentes], Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier (ICGM ICMMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut de Chimie du CNRS (INC), Photomécanique et analyse expérimentale en Mécanique des solides (PEM), Département Génie Mécanique et Systèmes Complexes (GMSC), Institut Pprime (PPRIME), Université de Poitiers-ENSMA-Centre National de la Recherche Scientifique (CNRS)-Université de Poitiers-ENSMA-Centre National de la Recherche Scientifique (CNRS)-Institut Pprime (PPRIME), Université de Poitiers-ENSMA-Centre National de la Recherche Scientifique (CNRS)-Université de Poitiers-ENSMA-Centre National de la Recherche Scientifique (CNRS), Centre hospitalier universitaire de Poitiers (CHU Poitiers), Mitochondrie : Régulations et Pathologie, Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Cellules souches leucémiques et thérapeuthiques, Université de Poitiers-Centre hospitalier universitaire de Poitiers (CHU Poitiers), Univ Angers, Okina, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), INSERM CIC 0802 (INSERM - CHU de Poitiers), Université de Poitiers-Centre hospitalier universitaire de Poitiers (CHU Poitiers)-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2008, 98 (11), pp.1830-8. ⟨10.1038/sj.bjc.6604378⟩مصطلحات موضوعية: Oncology, Cancer Research, Pathology, Multivariate analysis, [SDV]Life Sciences [q-bio], Loss of Heterozygosity, markers, 0302 clinical medicine, 80 and over, LOH, Prospective Studies, Prospective cohort study, Promoter Regions, Genetic, DNA Modification Methylases, Telomerase, Aged, 80 and over, 0303 health sciences, Univariate analysis, biology, Brain Neoplasms, Glioma, Middle Aged, DNA Repair Enzymes/genetics, Prognosis, 3. Good health, [SDV] Life Sciences [q-bio], 030220 oncology & carcinogenesis, Cohort, DNA Modification Methylases/genetics, Promoter Regions (Genetics), Adult, medicine.medical_specialty, Tumour heterogeneity, Decision Making, RT-PCR, Tumor Suppressor Proteins/genetics, outcome prediction, 03 medical and health sciences, Cyclin-Dependent Kinase Inhibitor p16/genetics, Glioma/genetics/mortality, Internal medicine, medicine, PTEN, Humans, neoplasms, Molecular Diagnostics, Cyclin-Dependent Kinase Inhibitor p16, 030304 developmental biology, Aged, Proportional hazards model, Tumor Suppressor Proteins, decision-making, DNA Methylation, medicine.disease, Telomerase/genetics, DNA Repair Enzymes, Brain Neoplasms/genetics/mortality, Multivariate Analysis, biology.protein, adult gliomas
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