المؤلفون: Yuan, Yuan, Ju, Young Seok, Kim, Youngwook, Li, Jun, Wang, Yumeng, Yoon, Christopher J, Yang, Yang, Martincorena, Inigo, Creighton, Chad J, Weinstein, John N, Xu, Yanxun, Han, Leng, Kim, Hyung-Lae, Nakagawa, Hidewaki, Park, Keunchil, Campbell, Peter J, Liang, Han

المساهمون: Borg, Åke, Creator, Ringnér, Markus, Creator, Staaf, Johan, Creator

المصدر: Nature Genetics. 52(3):342-352

مصطلحات موضوعية: Cell Cycle/genetics, DNA Copy Number Variations, DNA Repair/genetics, DNA, Mitochondrial/genetics, Genome, Human/genetics, Humans, Mutation, Neoplasms/genetics, Oxidative Phosphorylation, Sequence Analysis, RNA, Whole Genome Sequencing, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Medicinsk genetik, Medical and Health Sciences, Basic Medicine, Medical Genetics

URL الوصول: https://lup.lub.lu.se/record/8f1c62ab-fa08-4872-abf2-d33f162c1225
http://dx.doi.org/10.1038/s41588-019-0557-x

المؤلفون: Gerstung, Moritz, Jolly, Clemency, Leshchiner, Ignaty, Dentro, Stefan C, Gonzalez, Santiago, Rosebrock, Daniel, Mitchell, Thomas J, Rubanova, Yulia, Anur, Pavana, Yu, Kaixian, Tarabichi, Maxime, Deshwar, Amit, Wintersinger, Jeff, Kleinheinz, Kortine, Vázquez-García, Ignacio, Haase, Kerstin, Jerman, Lara, Sengupta, Subhajit, Macintyre, Geoff, Malikic, Salem, Donmez, Nilgun, Livitz, Dimitri G, Cmero, Marek, Demeulemeester, Jonas, Schumacher, Steven, Fan, Yu, Yao, Xiaotong, Lee, Juhee, Schlesner, Matthias, Boutros, Paul C, Bowtell, David D, Zhu, Hongtu, Getz, Gad, Imielinski, Marcin, Beroukhim, Rameen, Sahinalp, S Cenk, Ji, Yuan, Peifer, Martin, Markowetz, Florian, Mustonen, Ville, Yuan, Ke, Wang, Wenyi, Morris, Quaid D, Spellman, Paul T, Wedge, David C, Van Loo, Peter

المساهمون: Borg, Åke, Creator, Ringnér, Markus, Creator, Staaf, Johan, Creator

المصدر: Nature. 578(7793):122-128

مصطلحات موضوعية: DNA Repair/genetics, Evolution, Molecular, Gene Dosage, Genes, Tumor Suppressor, Genetic Variation, Genome, Human/genetics, Humans, Mutagenesis, Insertional/genetics, Neoplasms/genetics, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Medicinsk genetik, Medical and Health Sciences, Basic Medicine, Medical Genetics

URL الوصول: https://lup.lub.lu.se/record/7f8ffa06-e8e9-402f-9107-0b4d690e5da6
http://dx.doi.org/10.1038/s41586-019-1907-7

المؤلفون: Simon Grund Sørensen, Amruta Shrikhande, Gustav Alexander Poulsgaard, Mikkel Hovden Christensen, Johanna Bertl, Britt Elmedal Laursen, Eva R Hoffmann, Jakob Skou Pedersen

المصدر: Sørensen, S G, Shrikhande, A, Poulsgaard, G A, Christensen, M H, Bertl, J, Laursen, B E, Hoffmann, E R & Pedersen, J S 2023, ' Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns ', eLife, vol. 12 . https://doi.org/10.7554/eLife.81224
Sørensen, S G, Shrikhande, A, Poulsgaard, G A, Christensen, M H, Bertl, J, Laursen, B E, Hoffmann, E R & Pedersen, J S 2023, ' Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns ', eLife, vol. 12, e81224 . https://doi.org/10.7554/elife.81224

مصطلحات موضوعية: Male, General Immunology and Microbiology, General Neuroscience, DNA Helicases/genetics, repair deficiency, personalised medicine, Transcription Factors/genetics, mutational signatures, General Medicine, DNA damage response, BRCA2 Protein/genetics, Neoplasms/genetics, DNA Repair-Deficiency Disorders, General Biochemistry, Genetics and Molecular Biology, Nuclear Proteins/genetics, DNA Repair/genetics, Mutation, Humans, BRCA1 Protein/genetics, predictive modelling

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8fdd0c0855124ac5e59edd15de56b8
https://pure.au.dk/portal/da/publications/pancancer-association-of-dna-repair-deficiencies-with-wholegenome-mutational-patterns(6d841269-ef5f-41e2-a050-6f671e6994dd).html

المؤلفون: Poncin, Katy, Roba, Agnès, Jimmidi, Ravikumar, Potemberg, Georges, Fioravanti, Antonella, Francis, Nayla, Willemart, Kévin, Zeippen, Nicolas, Machelart, Arnaud, Biondi, Emanuele G., Muraille, Eric, Vincent, Stéphane P., De Bolle, Xavier

المصدر: Nature Communications, 10 (1), 4847 (2019)

مصطلحات موضوعية: Alkylation, Animals, Brucella abortus/genetics/metabolism, Brucellosis, DNA Damage/genetics, DNA Methylation/genetics, DNA Repair/genetics, Host-Pathogen Interactions/genetics, Macrophages/metabolism, Mice, RAW 264.7 Cells, Stress, Physiological/genetics, Vacuoles/metabolism, Human health sciences, Immunology & infectious disease, Sciences de la santé humaine, Immunologie & maladie infectieuse

Relation: urn:issn:2041-1723

URL الوصول: https://orbi.uliege.be/handle/2268/258070

المساهمون: Wei, Qingyi., Li, Lei, Dr., Chen, David, Dr.

مصطلحات موضوعية: DNA repair., Cancer -- Genetic aspects., Neoplasms -- etiology., Neoplasms -- genetics., DNA Damage -- genetics., DNA Repair -- genetics., DNA Repair-Deficiency Disorders., Genetic Predisposition to Disease.

المساهمون: Lankenau, Dirk-Henner.

مصطلحات موضوعية: Genomes., DNA repair., Genome -- genetics., DNA Repair -- genetics.

المساهمون: Siede, Wolfram., Kow, Yoke Wah., Doetsch, Paul W.

مصطلحات موضوعية: DNA repair., DNA Damage -- physiology., DNA Damage -- genetics., DNA Repair -- genetics., DNA Repair -- physiology.

المؤلفون: Antonio Rodriguez-Calero, John Gallon, Dilara Akhoundova, Sina Maletti, Alison Ferguson, Joanna Cyrta, Ursula Amstutz, Andrea Garofoli, Viola Paradiso, Scott A. Tomlins, Ekkehard Hewer, Vera Genitsch, Achim Fleischmann, Erik Vassella, Elisabeth J. Rushing, Rainer Grobholz, Ingeborg Fischer, Wolfram Jochum, Gieri Cathomas, Adeboye O. Osunkoya, Lukas Bubendorf, Holger Moch, George Thalmann, Charlotte K. Y. Ng, Silke Gillessen, Salvatore Piscuoglio, Mark A. Rubin

المساهمون: University of Zurich, Piscuoglio, Salvatore, Rubin, Mark A

المصدر: Nature communications, vol. 13, no. 1, pp. 2400
Rodriguez-Calero, Antonio; Gallon, John; Akhoundova, Dilara; Maletti, Sina; Ferguson, Alison; Cyrta, Joanna; Amstutz, Ursula; Garofoli, Andrea; Paradiso, Viola; Tomlins, Scott A; Hewer, Ekkehard; Genitsch, Vera; Fleischmann, Achim; Vassella, Erik; Rushing, Elisabeth J; Grobholz, Rainer; Fischer, Ingeborg; Jochum, Wolfram; Cathomas, Gieri; Osunkoya, Adeboye O; ... (2022). Alterations in homologous recombination repair genes in prostate cancer brain metastases. Nature Communications, 13(1), p. 2400. Springer Nature 10.1038/s41467-022-30003-5 <http://dx.doi.org/10.1038/s41467-022-30003-5>

مصطلحات موضوعية: Male, Multidisciplinary, Brain Neoplasms, Prostatic Neoplasms, Recombinational DNA Repair, General Physics and Astronomy, Brain Neoplasms/drug therapy, Brain Neoplasms/genetics, Humans, Mutation, Poly(ADP-ribose) Polymerase Inhibitors/pharmacology, Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use, Prostatic Neoplasms/drug therapy, Prostatic Neoplasms/genetics, Recombinational DNA Repair/genetics, 610 Medicine & health, 1600 General Chemistry, General Chemistry, Poly(ADP-ribose) Polymerase Inhibitors, General Biochemistry, Genetics and Molecular Biology, 3100 General Physics and Astronomy, 1300 General Biochemistry, Genetics and Molecular Biology, 10049 Institute of Pathology and Molecular Pathology, 570 Life sciences, biology

وصف الملف: Rodriguez_NatComm_2022.pdf - application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d339acb753118a030885e55b80a56cbb
https://www.zora.uzh.ch/id/eprint/222097/

المساهمون: Ehrlich, Melanie, 1945-

مصطلحات موضوعية: Genes, Tumor Suppressor., Cancer -- Genetic aspects., Neoplasms -- genetics., Cell Transformation, Neoplastic -- genetics., DNA Repair -- genetics., Genetic Predisposition to Disease -- genetics., Oncogenes., Genetic Predisposition to Disease.

المؤلفون: María del Carmen Conde-Rubio, Gilles Dubuis, Christian Widmann, Daniel Constantin

المصدر: The FEBS journal, vol. 289, no. 3, pp. 808-831

مصطلحات موضوعية: APOBEC, DNA End-Joining Repair, DNA Repair, DNA repair, DNA damage, Nucleolus, Cell Nucleolus/genetics, Cytidine Deaminase/genetics, DNA Breaks, Double-Stranded/drug effects, DNA Damage/drug effects, DNA Damage/genetics, DNA End-Joining Repair/genetics, DNA Repair/drug effects, DNA Repair/genetics, Etoposide/pharmacology, Gene Expression Regulation/drug effects, Genome, Human/genetics, Homologous Recombination/genetics, Humans, Multigene Family/genetics, Mutagens/pharmacology, Mutation/genetics, Tumor Suppressor Protein p53/genetics, APOBEC3C, cancer biology, nucleolus, p53, Biology, Biochemistry, Cytidine Deaminase, DNA Breaks, Double-Stranded, Homologous Recombination, Molecular Biology, Etoposide, Genome, Human, Cell Biology, Cell biology, Non-homologous end joining, genomic DNA, Gene Expression Regulation, Multigene Family, Mutation, Human genome, Tumor Suppressor Protein p53, Homologous recombination, Cell Nucleolus, DNA Damage, Mutagens

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed082bf9274bb2db8cd80d43f41b48dc
https://serval.unil.ch/notice/serval:BIB_549304C0D4F3