المؤلفون: Jacob Mentzel, Laura S. Hildebrand, Lukas Kuhlmann, Rainer Fietkau, Luitpold V. Distel

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 11, p 5629 (2024)

مصطلحات موضوعية: HNSCC, DNA damage response inhibitor, PARP inhibitor, DNA-PK inhibitor, kinase inhibitor, radiosensitivity, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/25/11/5629; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/f759a208ea7743f682c5b679efc11488

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المؤلفون: Xiang-Zhong Liu, Mi Zhou, Chun-Chun Du, Hong-Hong Zhu, Xi Lu, Shou-Lun He, Guang-Hui Wang, Ting Lin, Wen-Jing Tian, Hai-Feng Chen

المصدر: Biomedicines, Vol 9, Iss 10, p 1473 (2021)

مصطلحات موضوعية: Guttiferae, Hypericum elodeoides, acylphloroglucinol, biosynthetic pathway, DNA damage response inhibitor, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2227-9059/9/10/1473; https://doaj.org/toc/2227-9059

URL الوصول: https://doaj.org/article/1ce9ed445995477387859556503cd17c

المؤلفون: Clara Dobler, Tina Jost, Markus Hecht, Rainer Fietkau, Luitpold Distel

المصدر: Cells, Vol 9, Iss 9, p 2012 (2020)

مصطلحات موضوعية: HNSCC, DNA damage response inhibitor, kinase inhibitor, senescence, ATM, ATR, Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/9/2012; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/89778952c7f142d7b3ee5fc482d6e5e7

المؤلفون: Tom Haswell, Matthew G Krebs, Chris J. Twelves, Katrina Walker, Corinne Faivre-Finn, David Sebag-Montefoire, Paul Shaw, Ahmed Salem, Nicola L. Hannaway, Anthony J. Chalmers, Alexandra Gilbert, R. Young, Geraldine Murden, Crispin T. Hiley, Sarah Brown, Jamie B. Oughton, Gerard G Hanna, Anderson J. Ryan, Rachel Phillip, Alastair Greystoke, Fiona Collinson, Kevin Franks, Martin Forster, Gerard Walls, Stephen Harrow, Samantha Hinsley

المصدر: Walls, G M, Oughton, J B, Chalmers, A J, Brown, S, Collinson, F, Forster, M D, Franks, K N, Gilbert, A, Hanna, G G, Hannaway, N, Harrow, S, Haswell, T, Hiley, C T, Hinsley, S, Krebs, M, Murden, G, Phillip, R, Ryan, A J, Salem, A, Sebag-Montefoire, D, Shaw, P, Twelves, C J, Walker, K, Young, R J, Faivre-Finn, C & Greystoke, A 2020, ' CONCORDE: A phase I platform study of novel agents in combination with conventional radiotherapy in non-small-cell lung cancer ', Clinical and translational radiation oncology, vol. 25, pp. 61-66 . https://doi.org/10.1016/j.ctro.2020.09.006
Clinical and Translational Radiation Oncology
Clinical and Translational Radiation Oncology, Vol 25, Iss, Pp 61-66 (2020)

مصطلحات موضوعية: Oncology, ATR, Ataxia telangiectasia and Rad3 related, Sequential chemoradiotherapy, medicine.medical_treatment, R895-920, PFS, Progression free survival, RP2D, Recommended phase II dose, TNM, Tumour node metastasis, 030218 nuclear medicine & medical imaging, PET, Positron emission tomography, chemistry.chemical_compound, Medical physics. Medical radiology. Nuclear medicine, CRT, Chemoradiotherapy, DNA, Deoxyribonucleic acid, 0302 clinical medicine, Non-small cell lung cancer, PROMs, Patient-reported outcome measures, DLT, Dose limiting toxicity, Platform trial, NSCLC, Non-small cell lung cancer, TiTE-CRM, Time to event continual reassessment method, RC254-282, SRC, Safety review committee, RT, Radiotherapy, Manchester Cancer Research Centre, DDRi, DNA damage response inhibitor, ECOG, Eastern Cooperative Oncology Group, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Common Terminology Criteria for Adverse Events, DNA damage repair inhibitor, RECIST, Response evaluation criteria in solid tumours, EORTC, European Organisation for Research and Treatment of Cancer, 030220 oncology & carcinogenesis, CT, Computed tomography, PARP, Poly (ADP-ribose) polymerase, medicine.drug, SACT, Systemic anti-cancer therapy, medicine.medical_specialty, ATM, Ataxia telangiectasia mutated, Article, Olaparib, 03 medical and health sciences, SDG 3 - Good Health and Well-being, DNA-PK, DNA-dependent protein kinase, Internal medicine, medicine, Radiology, Nuclear Medicine and imaging, IMPs, Investigational medicinal products, Continual reassessment method, Progression-free survival, Lung cancer, ICRU, International Commission on Radiation Units and Measurements, Temozolomide, CTRad, Clinical and Translational Radiotherapy Research Working Group, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, CTCAE, Common terminology criteria for adverse events, cfDNA, Cell-free DNA, medicine.disease, MRC, Medical Research Council, NCRI, National Cancer Research Institute, Clinical trial, Radiation therapy, LA, Locally advanced, chemistry, business, Chemoradiotherapy

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab793db3c955a860dc79fcb06479e299
https://pure.qub.ac.uk/en/publications/concorde-a-phase-i-platform-study-of-novel-agents-in-combination-with-conventional-radiotherapy-in-nonsmallcell-lung-cancer(7a8b2ae9-083a-4970-a3aa-cc71031461f1).html

المؤلفون: Dobler, Clara, Jost, Tina, Hecht, Markus, Fietkau, Rainer, Distel, Luitpold

المصدر: Cells
Cells, Vol 9, Iss 2012, p 2012 (2020)
Volume 9
Issue 9

مصطلحات موضوعية: Male, senescence, Pyridines, kinase inhibitor, Apoptosis, homologous recombination, Ataxia Telangiectasia Mutated Proteins, HNSCC, Article, Cell Line, Tumor, Radiation, Ionizing, Humans, DNAPK, ddc:610, lcsh:QH301-705.5, Protein Kinase Inhibitors, Cellular Senescence, DNA damage response inhibitor, Squamous Cell Carcinoma of Head and Neck, TOR Serine-Threonine Kinases, Cell Cycle, Isoxazoles, Fibroblasts, Triazoles, ATR, lcsh:Biology (General), Head and Neck Neoplasms, radiosensitivity, Pyrazines, ATM, Quinolines, ionizing radiation, DNA Damage, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e77fb7fa58feb20ee5c55641f1898695
https://pubmed.ncbi.nlm.nih.gov/32883016

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المؤلفون: Walls GM; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Northern Ireland, UK., Oughton JB; Leeds Institute of Clinical Trials Research, University of Leeds, England, UK., Chalmers AJ; Institute of Cancer Sciences, University of Glasgow, Scotland, UK., Brown S; Leeds Institute of Clinical Trials Research, University of Leeds, England, UK., Collinson F; Leeds Institute of Clinical Trials Research, University of Leeds, England, UK., Forster MD; Department of Oncology, UCL Cancer Institute, England, UK., Franks KN; St James' Institute of Oncology, University of Leeds, England, UK., Gilbert A; St James' Institute of Oncology, University of Leeds, England, UK., Hanna GG; Sir Peter MacCallum Department of Oncology, University of Melbourne, Australia., Hannaway N; Newcastle University, Newcastle upon Tyne, England, UK., Harrow S; The Beatson West of Scotland Cancer Centre, Glasgow, Scotland, UK., Haswell T; Patient and Public Involvement Advocacy, UK., Hiley CT; Department of Oncology, UCL Cancer Institute, England, UK., Hinsley S; Leeds Institute of Clinical Trials Research, University of Leeds, England, UK.; Institute of Cancer Sciences, University of Glasgow, Scotland, UK., Krebs M; Faculty of Biology, Medicine and Health, University of Manchester, England, UK., Murden G; Leeds Institute of Clinical Trials Research, University of Leeds, England, UK., Phillip R; Leeds Institute of Clinical Trials Research, University of Leeds, England, UK., Ryan AJ; Oxford Institute for Radiation Oncology, University of Oxford, Oxford, England, UK., Salem A; The Christie NHS Foundation Trust/University of Manchester, Manchester, England, UK., Sebag-Montefoire D; St James' Institute of Oncology, University of Leeds, England, UK., Shaw P; Velindre University NHS Trust, Cardiff, Wales, UK., Twelves CJ; St James' Institute of Oncology, University of Leeds, England, UK., Walker K; Leeds Institute of Clinical Trials Research, University of Leeds, England, UK., Young RJ; Academic Unit of Clinical Oncology, Weston Park Hospital, Sheffield, England, UK., Faivre-Finn C; Oxford Institute for Radiation Oncology, University of Oxford, Oxford, England, UK., Greystoke A; Newcastle University, Newcastle upon Tyne, England, UK.

المصدر: Clinical and translational radiation oncology [Clin Transl Radiat Oncol] 2020 Sep 22; Vol. 25, pp. 61-66. Date of Electronic Publication: 2020 Sep 22 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Ireland Ltd. on behalf of European Society for Radiotherapy and Oncology Country of Publication: Ireland NLM ID: 101713416 Publication Model: eCollection Cited Medium: Internet ISSN: 2405-6308 (Electronic) Linking ISSN: 24056308 NLM ISO Abbreviation: Clin Transl Radiat Oncol Subsets: PubMed not MEDLINE