نتائج البحث - "DNA replication: drug effects"

1

رسالة جامعية

Action and interaction of growth factors and regulatory molecules in vascular cells : with special reference to the IGF-I-system

المؤلفون: Dahlfors, Gunilla

مصطلحات موضوعية: Endothelium, vascular: metabolism, Insulin-like growth factor I: pharmacology, Muscle, smooth, vascular: metabolism, Molecular biology, Insulin-like growth-factor-binding proteins: genetics, Platelet-derived growth factor: pharmacology: Dna replication: drug effects, DNA replication: drug effects, Platelet-derived growth factor: pharmacology

URL الوصول: http://www.bibl.liu.se/liupubl/disp/disp2000/med637s.pdf

2

رسالة جامعية

Regulation of ongoing DNA synthesis in normal and neoplastic brain tissue

المؤلفون: Yakisich, Juan Sebastián

مصطلحات موضوعية: DNA -- biosynthesis, DNA, neoplasm -- biosynthesis, Brain neoplasms, Brain -- metabolism, Glioma -- drug therapy, DNA replication -- drug effects

URL الوصول: http://diss.kib.ki.se/2005/91-7140-433-3/

Degree: Diss. (sammanfattning) Stockholm : Karolinska institutet, 2005

3

Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication

المؤلفون: Stephanie Munk, Mark G. Frattini, Amnon Koren, Jesper V. Olsen, Camille Gelot, Ruth Santos, Kelly A. George, Yoshitaka Kawasoe, Tatsuro S. Takahashi, Prasad V. Jallepalli, Steven A. McCarroll, Mathew J. K. Jones

المصدر: Mol Cell
Jones, M J K, Gelot, C, Munk, S, Koren, A, Kawasoe, Y, George, K A, Santos, R E, Olsen, J V, McCarroll, S A, Frattini, M G, Takahashi, T S & Jallepalli, P V 2021, ' Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication ', Molecular Cell, vol. 81, no. 3, pp. 426-441.e8 . https://doi.org/10.1016/j.molcel.2021.01.004

مصطلحات موضوعية: Time Factors, Xenopus, Cell Cycle Proteins, Adaptor Proteins, Signal Transducing/genetics, Ataxia Telangiectasia Mutated Proteins, Substrate Specificity, Xenopus laevis, 0302 clinical medicine, Ataxia Telangiectasia Mutated Proteins/genetics, Phosphorylation, 0303 health sciences, biology, Kinase, Phosphoproteomics, Cell biology, DNA-Binding Proteins, S Phase Cell Cycle Checkpoints, Female, DNA Replication, Protein-Serine-Threonine Kinases/genetics, Protein subunit, Transcription Factors/genetics, Replication Origin, Protein Serine-Threonine Kinases, Article, 03 medical and health sciences, Cyclin-dependent kinase, Animals, Humans, Protein Kinase Inhibitors, Molecular Biology, Adaptor Proteins, Signal Transducing, 030304 developmental biology, Cell Cycle Proteins/genetics, Checkpoint Kinase 1/genetics, Cohesin, DNA replication, Cell Biology, DNA Replication/drug effects, HCT116 Cells, biology.organism_classification, HEK293 Cells, Protein Kinase Inhibitors/pharmacology, Checkpoint Kinase 1, biology.protein, DNA-Binding Proteins/genetics, 030217 neurology & neurosurgery, HeLa Cells, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fce570e20ce495374ccaa3fece0279
https://doi.org/10.1016/j.molcel.2021.01.004

4

دورية أكاديمية

Biological characterization of an acid-sensitive growth factor from human platelets: role in the proliferation of human melanoma and bovine endothelial cells.

المؤلفون: Sipes, N J, Meyskens, F L, Jr, Bregman, M D

المصدر: Biochemical and biophysical research communications. 138(2)

مصطلحات موضوعية: Animals, Aorta: cytology, drug effects, Blood Platelets: physiology, Cattle, Cell Division: drug effects, Cells, Cultured, Chromatography, Gel, Chromatography, High Pressure Liquid, DNA Replication: drug effects, Endothelium: cytology, drug effects, Growth Substances: blood, isolation & purification, pharmacology, Humans, Hydrogen-Ion Concentration, Melanoma: pathology, Thymidine: metabolism, growth factor, animal cell, blood and hemopoietic system, cattle, endothelium cell, high performance liquid chromatography, human, human cell, melanoma, priority journal, thrombocyte, Animal, Aorta, Blood Platelets, Cattle, Cell Division, Cells, Cultured, Chromatography, Gel, Chromatography, High Pressure Liquid, DNA Replication, Endothelium, Growth Substances, Human, Hydrogen-Ion Concentration, Melanoma, Support, U.S. Gov't, P.H.S., Thymidine

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0515r8rr

5

TORC2 Signaling Pathway Guarantees Genome Stability in the Face of DNA Strand Breaks

المؤلفون: Susan M. Gasser, Christian Studer, Stephen B. Helliwell, Ireos Filipuzzi, Michael Stahl, Robbie Loewith, Kenji Shimada, Andrew Seeber, N. Rao Movva, Dominic Hoepfner

المصدر: Molecular Cell, Vol. 51, No 6 (2013) pp. 829-839
Molecular Cell
Molecular cell

مصطلحات موضوعية: Ionizing, Mutant, Actins/antagonists & inhibitors/metabolism, Heterocyclic/pharmacology, Synthetic lethality, Saccharomyces cerevisiae/genetics, Glycogen Synthase Kinase 3, chemistry.chemical_compound, 0302 clinical medicine, ddc:590, Transcription (biology), Radiation, Ionizing, Chromosomes/drug effects/genetics/radiation effects, Saccharomyces cerevisiae Proteins/antagonists & inhibitors/genetics/metabolism, 0303 health sciences, Radiation, Effector, TOR Serine-Threonine Kinases, Transcription Factors/antagonists & inhibitors/genetics/metabolism, 3. Good health, 030220 oncology & carcinogenesis, Thiazolidines, TOR Serine-Threonine Kinases/antagonists & inhibitors/genetics/metabolism, Signal Transduction, DNA Replication, Saccharomyces cerevisiae Proteins, DNA damage, Zeocin, Saccharomyces cerevisiae, Bleomycin/pharmacology, Mechanistic Target of Rapamycin Complex 2, Biology, Chromosomes, Genomic Instability, Bleomycin, Bridged Bicyclo Compounds, 03 medical and health sciences, ddc:570, Glycogen Synthase Kinase 3/metabolism, Molecular Biology, Actin, 030304 developmental biology, Signal Transduction/drug effects/radiation effects, Genomic Instability/drug effects/radiation effects, Cell Biology, Thiazolidines/pharmacology, Bridged Bicyclo Compounds, Heterocyclic, Actin cytoskeleton, Multiprotein Complexes/antagonists & inhibitors/genetics/metabolism, Molecular biology, Actins, chemistry, Multiprotein Complexes, DNA Replication/drug effects/radiation effects, DNA Damage/genetics, DNA Damage, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b68a1067a0c7d9e4d83ae993a3f440

View record from ScienceDirect

6

Exposure to acute hypoxia induces a transient DNA damage response which includes Chk1 and TLK1

المؤلفون: Zuzana Bencokova, Chris McGurk, Ester M. Hammond, Isabel M. Pires

المصدر: Pires, I M, Bencokova, Z, McGurk, C & Hammond, E M 2010, ' Exposure to acute hypoxia induces a transient DNA damage response which includes Chk1 and TLK1 ', Cell cycle (Georgetown, Tex.), vol. 9, no. 13, pp. 2502-2507 . https://doi.org/10.4161/cc.9.13.12059

مصطلحات موضوعية: DNA Replication, DNA Repair, DNA damage, DNA repair, DNA Repair/drug effects, Biology, Protein Serine-Threonine Kinases, cell Hypoxia/drug effects, Models, Biological, environment and public health, Signal Transduction/drug effects, medicine, Rad51 Recombinase/metabolism, Protein Serine-Threonine Kinases/metabolism, Phosphorylation, Molecular Biology, Oxygen/pharmacology, checkpoint Kinase 1, Manchester Cancer Research Centre, Extra View, ResearchInstitutes_Networks_Beacons/mcrc, DNA replication, Phosphorylation/drug effects, Cell Biology, Hypoxia (medical), Cell cycle, DNA Replication/drug effects, Molecular biology, Cell Hypoxia, Cell biology, Oxygen, enzymes and coenzymes (carbohydrates), Apoptosis, Checkpoint Kinase 1, Protein Kinases/metabolism, Rad51 Recombinase, Signal transduction, medicine.symptom, biological phenomena, cell phenomena, and immunity, Protein Kinases, Developmental Biology, Signal Transduction, DNA Damage