نتائج البحث - "DNA topoisomerase (ATP hydrolysing) A"

المساهمون: Uludağ Üniversitesi/Veterinerlik Fakültesi/Su Hayvanları Hastalıkları Bölümü., Duman, Muhammed, Altun, Soner, T-1697-2019, AAG-8518-2021

مصطلحات موضوعية: Veterinary sciences, Veterinary medicine, Acterial protein, Turkey, Motile aeromonas septicemia, Aeromonas salmonicida, Aeromonas veronii, Aquaculture, Gene sequence, Polymerase Chain Reaction, SPP, law.invention, Lactococcus garvieae, Ribosomal-RNA gene, Pathogencity, Phylogeny, Phylogenetic analysis, Coinfection, Glycerophospholipid-cholesterol acyltransferase, Morganella psychrotolerans infection, Aeromonas molluscorum, Housekeeping gene, Aeromonas hydrophila, Black Sea, DNA Gyrase, Oncorhynchus mykiss, Water temperature, Infectious pancreatic necrosis, Veterinary (miscellaneous), Fish farming, Fisheries, Aeromonas encheleia, GCAT-PCR, Microbiology, Article, 03 medical and health sciences, Pathogenic aeromonas, Bacterial Proteins, Goldfish, Enterobacter cloacae, Genetics, Salmo trutta, Citrobacter gillenii infection, DNA topoisomerase (ATP hydrolysing), Zebra fish, Animal, Outbreak, Water, Enteric redmouth disease, 030104 developmental biology, DNA topoisomerase (ATP hydrolysing) B, Gram negative infection, Rainbow trout, Antibiotic-resistance, Gram-Negative Bacterial Infections, Acyltransferases, Phylogenetic tree, 0301 basic medicine, Bacterium identification, Identification, Aeromonas dhakensis, Physiology, Marine & freshwater biology, Bacterial strain, Animal tissue, Opportunistic infection, Fish Diseases, Aeromonas, Aeromonas Hydrophila, Virulence, Citrobacter, law, Turkey (bird), Maximum likelihood method, Prevalence, Mixed infection, Aeromonas caviae, Polymerase chain reaction, Hydrophila, Classification, Aeromonas bestiarum, Glycerophospholipid, GenBank, Bacterium isolation, Molecular diagnosis, Phenylacetic acid, Lactococcus garvieae infection, Gyrb, Bacterium isolate, Guanine, RNA 16S, Acyltransferase, Flavobacterium psychrophilum infection, Aquatic Science, Biology, Opportunistic Infections, Cytosine, Aeromonas media, Animals, Fish disease, Cholesterol acyltransferase, Morganella, Adenine, Adipic acid, biology.organism_classification, Nonhuman, Enterobacter cloacae infection, Virulence genes, Biochemical analysis, Data analysis software, Controlled study, Thymine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d637d4d6e21797709444b951c89db7
https://avesis.erciyes.edu.tr/publication/details/d37e00e5-2958-4c17-9b96-0f17e7ba252c/oai

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Structural modification of ellipticine derivatives with alkyl groups of varying length is influential on their effects on human DNA topoisomerase II: a combined experimental and computational study

المؤلفون: Yavuz Ergun, Serdar Durdagi, Zeki Topcu, Á. Kulmány, M. Zaka, Kader Sahin, István Zupkó, Sevil Zencir, M. Kuskucu, V. Akyildiz, Hilmi Orhan

المساهمون: Ege Üniversitesi

مصطلحات موضوعية: Iodide, Intercalation (chemistry), cisplatin, IC50, chemistry.chemical_compound, ellipticine derivative, General Pharmacology, Toxicology and Pharmaceutics, antineoplastic agent, chemistry.chemical_classification, Ellipticine derivatives, biology, n2 hexyl n methyl 5 demethyl ellipticinium bromide, n2 ethyl n methyl 5 demethyl ellipticinium bromide, drug cytotoxicity, drug effect, quantitative structure activity relation, unclassified drug, enzyme activity, DNA topoisomerase II, n2 (3 cyanopropyl) n methyl 5 demethyl ellipticinium chloride, antiproliferative activity, Stereochemistry, In silico, tumor cell, Anticancer drugs, Article, alkyl group, drug mechanism, controlled study, human, DNA topoisomerase (ATP hydrolysing), Alkyl, cell viability, n2 cyanomethyl n methyl 5 demethyl ellipticinium iodide, catalysis, Carbazole, binding site, Topoisomerase, human cell, Organic Chemistry, molecular docking, molecular dynamics, drug structure, Enzyme, chemistry, organohalogen derivative, n2 (carboxyaminoethyl) n methyl 5 demethyl ellipticinium bromide, biology.protein, Nucleic acid, drug synthesis, computer model

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2de3987d1a58efe767ceaedadbde0b
https://avesis.deu.edu.tr/publication/details/9e8b704c-2c4e-4d59-922b-200d244321d7/oai

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Selected Ellipticine Derivatives, Known To Target Topoisomerase Ii, Suppress The Alternative Lengthening Of Telomere (Alt) Pathway In Telomerase-Negative Cells

المؤلفون: Joel-Sean Hsu, Yavuz Ergun, Sevil Zencir, Zeki Topcu, Guan-Ling Chou, Meng-Hsun Hsieh, Shu-Chun Teng, Tsai-Kun Li

المساهمون: Ege Üniversitesi

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Telomerase, MTS assay, telomerase inhibitor, Fluorescent Antibody Technique, 0302 clinical medicine, ellipticine derivative, telomere length, Topoisomerase II Inhibitors, genetics, ALT cell line, Ellipticines, telomere homeostasis, antineoplastic agent, In Situ Hybridization, Fluorescence, gyrase inhibitor, chemistry.chemical_classification, Ellipticine derivatives, DNA strand breakage, SaOS-2 cell line, biology, medicine.diagnostic_test, drug effect, General Medicine, Alternative lengthening of telomere, unclassified drug, female, Oncology, priority journal, 030220 oncology & carcinogenesis, DNA supercoil, cytotoxicity, DNA topoisomerase II, phenotype, Antineoplastic Agents, telomerase, chemistry, Article, Cell Line, 03 medical and health sciences, comet assay, medicine, Humans, controlled study, Viability assay, human, DNA topoisomerase (ATP hydrolysing), drug selectivity, immunofluorescence, fluorescence in situ hybridization, cell viability, Topoisomerase, human cell, icrf 93, Anti-cancer therapeutics, In vitro, Telomere, 030104 developmental biology, Enzyme, Cancer research, biology.protein, ellipticine, Fluorescence in situ hybridization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0b048c1d0e38533aa90570de7e4a71
https://aperta.ulakbim.gov.tr/record/5665

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رسالة جامعية

Topoisomerase II and drug resistance in leukemic cells

المؤلفون: Zhou, Rong

مصطلحات موضوعية: DNA topoisomerase (ATP-hydrolysing): metabolism

URL الوصول: http://diss.kib.ki.se/2001/91-628-4738-4/

Degree: Diss. (sammanfattning) Stockholm : Karol. inst., 2001

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Molecular characterization and antimicrobial resistance profile of atypical Citrobacter gillenii and Citrobacter sp. isolated from diseased rainbow trout (Oncorhynchus mykiss)

المؤلفون: Ayse Gul Buyukekiz, Soner Altun, Fikri Balta, Muhammed Duman, Izzet Burcin Saticioglu

المساهمون: Uludağ Üniversitesi/Veteriner Fakültesi/Su Hayvanları Hastalıkları Anabilim Dalı., Duman, Muhammed, Satıcıoğlu, İzzet Burçin, Büyükekiz, Ayşe Gül, Altun, Soner, AAG-8518-2021, AAD-4156-2019, T-1697-2019

مصطلحات موضوعية: 0301 basic medicine, Florfenicol, Bacterium identification, Identification, Broth dilution, Unclassified drug, Antibiotic resistance, Aquaculture, Microbial sensitivity tests, Molecular typing, Gene sequence, Atypical citrobacter, Genes, essential, chemistry.chemical_compound, Bacterial protein, Citrobacter, Ggenotype, Immunology and Allergy, Gyrb gene, Antiinfective agent, Phylogeny, Priority journal, Drug resistance, bacterial, biology, Bacterial gene, Genes, bacterial, Genetic analysis, DNA gyrase, Microbial sensitivity test, Molecular characterization, Housekeeping gene, Phenotype, TetA protein, Aquacultur, Oxidoreductase, GenBank, Oncorhynchus mykiss, Infectious diseases, Bacterium isolation, Freundii, medicine.drug, Microbiology (medical), Bacterium isolate, Genotype, Tetracycline, Sequence analysis, RNA 16S, 030106 microbiology, Immunology, DNA sequence, TetD protein, Sulfonamide, Microbiology, Article, 03 medical and health sciences, Enterobacteriaceae, Anti-bacterial agents, DNA, bacterial, medicine, Citrobacter Freundii, Enterobacteriaceae Infections, Amikacin, Genetics, Animals, Pathogenicity, Ssulfamethoxazole, Fish diseases, DNA topoisomerase (ATP hydrolysing), Genus aeromonas, Fish disease, Rapid test, SulI protein, Pharmacology & pharmacy, Animal, Dna hybridization, Sequence analysis, DNA, 16S ribosomal RNA, biology.organism_classification, Bacterial DNA, Nonhuman, Drug effect, Antimicrobial resistance genes, 030104 developmental biology, RNA, ribosomal, 16S, chemistry, Isolation and purification, Essential gene, DNA topoisomerase (ATP hydrolysing) B, TetB protein, Biochemical analysis, Citrobacter gillenii, Sp-nov, Controlled study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c1250b310bf74e5ee56977061c8130
http://hdl.handle.net/11452/29300

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Novel pyranopyrazole derivatives comprising a benzoxazole core as antimicrobial inhibitors: Design, synthesis, microbial resistance and machine aided results

المؤلفون: Jarem Raul Garcia, Avula Krishna Kumari, Guda Mallikarjuna Reddy, Vemulapati Hanuman Reddy

المصدر: Bioorganic Chemistry

مصطلحات موضوعية: ANTIINFECTIVE AGENT, BENZOXAZOLE DERIVATIVE, ANTIBACTERIAL ACTIVITY, DRUG PROTEIN BINDING, CIPROFLOXACIN, UNCLASSIFIED DRUG, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Anti-Infective Agents, Drug Discovery, MOLECULAR DOCKING, Topoisomerase II Inhibitors, Moiety, PRIORITY JOURNAL, HYDROPHOBICITY, Benzoxazoles, Chemistry, BACTERIAL ENZYME, Biological activity, PYRAN DERIVATIVE, Bacterial Infections, Benzoxazole, Antimicrobial, 4 PHENYL 3 [[(5 CHLOROBENZO[D]OXAZOL 2 YL)THIO]METHYL] 6 AMINO 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CARBONITRILE, BINDING AFFINITY, 4 (3 HYDROXYPHENYL) 3 [[(5 CHLOROBENZO[D]OXAZOL 2 YL)THIO]METHYL] 6 AMINO 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CARBONITRILE, Molecular Docking Simulation, DNA Gyrase, DRUG DESIGN, Antibacterial activity, BINDING ENERGY, SYNTHESIS, ANTIFUNGAL ACTIVITY, 4 (2 CHLOROPHENYL) 3 [[(5 CHLOROBENZO[D]OXAZOL 2 YL)THIO]METHYL] 6 AMINO 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CARBONITRILE, Hydrophobic effect, Drug Resistance, Fungal, ZONE OF INHIBITION, Drug Resistance, Bacterial, ANTIBIOTIC RESISTANCE, NONHUMAN, Humans, ANTIMICROBIAL, ARTICLE, DRUG STRUCTURE, Molecular Biology, COMPUTER AIDED DESIGN, GREEN CHEMISTRY, ANTIMICROBIAL ACTIVITY, 4 (2 TOLYL) 3 [[(5 CHLOROBENZO[D]OXAZOL 2 YL)THIO]METHYL] 6 AMINO 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CARBONITRILE, Bacteria, 010405 organic chemistry, DRUG SYNTHESIS, DNA TOPOISOMERASE (ATP HYDROLYSING), HYDROGEN BOND, Organic Chemistry, KETOCONAZOLE, Fungi, Green Chemistry Technology, PYRAZOLE DERIVATIVE, DOCKING STUDIES, Combinatorial chemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Mycoses, Docking (molecular), Drug Design, Pyrazoles, DNA

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d67f7ca4a79db5234307d1e5fccfb1
https://doi.org/10.1016/j.bioorg.2020.103908

View record from ScienceDirect

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Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin

المؤلفون: Yaidelys Iglesias-Torrens, Anna Maria Dionisi, Alessandra Carattoli, Aurora García-Fernández, Sergio Arena, Ida Luzzi

المصدر: Frontiers in Microbiology
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Frontiers in Microbiology, Vol 9 (2018)

مصطلحات موضوعية: 0301 basic medicine, antibiotic resistance, 2 naphthylamine, polymerase chain reaction, lcsh:QR1-502, Campylobacter lari, zone of inhibition, Drug resistance, Campylobacter coli, medicine.disease_cause, lcsh:Microbiology, survival analysis, gene mutation, Original Research, Campylobacter, ribosomal protein L22, unclassified drug, genetic code, Campylobacter concisus, female, Italy, erythromycin, campylobacteriosis, medicine.drug, disk diffusion, Microbiology (medical), Bacterial Gastroenteritis, phenotype, Tetracycline, prevalence, 030106 microbiology, DNA sequence, Campylobacteriosis, Biology, Campylobacter upsaliensis, Microbiology, Campylobacter jejuni, Article, ciprofloxacin, DNA topoisomerase (ATP hydrolysing) A, fusion protein, phenylalanine arginine 2 naphthylamide, ribosomal protein L4, ribosome protein, RNA 23S, tetracycline, unclassified drug, amino acid sequence, antibiotic sensitivity, bacterium isolation, Campylobacter fetus, computer model, efflux ratio, feces analysis, human, male, multidrug resistance, Campylobacter coil, resistance, 03 medical and health sciences, Antibiotic resistance, medicine, medicine.disease, biology.organism_classification, amino acid sequence

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af24bf706513b85069740400ea848cbd
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=14030

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Effects of Secondary Metabolites from the Fungus Septofusidium berolinense on DNA Cleavage Mediated by Human Topoisomerase IIα

المؤلفون: Neil Osheroff, Güner Ekiz, Zeki Topcu, Kendra R. Vann, Sevil Zencir, Erdal Bedir

المساهمون: Ege Üniversitesi

المصدر: Chemical research in toxicology. 29(3)

مصطلحات موضوعية: 0301 basic medicine, 2 hydroxymethyl 3 propylcyclohexa 2,5 diene 1,4 dione, natural product, Metabolite, 3,6 dihydroxy 2 propylbenzaldehyde, DNA topoisomerase II alpha, Secondary Metabolism, Toxicology, etoposide, chemistry.chemical_compound, Plasmid, 2-hydroxymethyl-3-propylcyclohexa-2,5-diene-1,4-dione, Etoposide, chemistry.chemical_classification, DNA cleavage, biology, Molecular Structure, drug cytotoxicity, fungus, General Medicine, 3,6-dihydroxy-2-propylbenzaldehyde, unclassified drug, 3. Good health, Quinone, DNA-Binding Proteins, filamentous fungus, Biochemistry, cytotoxic agent, Benzaldehydes, drug potency, antagonist potency, medicine.drug, oxidation, Septofusidium berolinense, chemistry, DNA-binding protein, Antigens, Neoplasm/*metabolism, Benzaldehydes/chemistry/metabolism/*pharmacology, Cyclohexanones/chemistry/metabolism/*pharmacology, DNA Cleavage, DNA Topoisomerases, Type II/*metabolism, DNA-Binding Proteins/*metabolism, Fungi/*chemistry/*metabolism, Humans, benzaldehyde derivative, Article, 03 medical and health sciences, Antigens, Neoplasm, plasmid, hydroquinone derivative, drug mechanism, medicine, controlled study, human, potassium ferricyanide, DNA topoisomerase (ATP hydrolysing), quinone derivative, Bond cleavage, DNA topoisomerase inhibitor, nonhuman, 030102 biochemistry & molecular biology, Cyclohexanones, Topoisomerase, Fungi, dithiothreitol, DNA binding protein, Ascomycetes, drug efficacy, DNA topoisomerase (ATP hydrolysing) A, 030104 developmental biology, Enzyme, DNA Topoisomerases, Type II, concentration response, chemical structure, biology.protein, amino terminal sequence, drug metabolite, cyclohexanone derivative, metabolism, tumor antigen

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22dc05536d096bbca50247ac3c97254d
https://pubmed.ncbi.nlm.nih.gov/26894873

Find this issue from the American Chemical Society

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