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1دورية أكاديميةMarburg virus survivor immune responses are Th1 skewed with limited neutralizing antibody responses.
المؤلفون: Stonier SW; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD., Herbert AS; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD., Kuehne AI; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD., Sobarzo A; Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel., Habibulin P; Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel., Dahan CVA; Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel., James RM; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD., Egesa M; Uganda Research Unit on AIDS, Medical Research Council/Uganda Virus Research Institute, Entebbe, Uganda.; Department of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, Kampala, Uganda., Cose S; Uganda Research Unit on AIDS, Medical Research Council/Uganda Virus Research Institute, Entebbe, Uganda.; Department of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, Kampala, Uganda.; London School of Hygiene & Tropical Medicine, London, England, UK., Lutwama JJ; Department of Arbovirology, Emerging, and Re-emerging Infection, Uganda Virus Research Institute, Entebbe, Uganda., Lobel L; Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Department of Arbovirology, Emerging, and Re-emerging Infection, Uganda Virus Research Institute, Entebbe, Uganda., Dye JM; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD john.m.dye1.civ@mail.mil llobel@bgu.ac.il.
المصدر: The Journal of experimental medicine [J Exp Med] 2017 Sep 04; Vol. 214 (9), pp. 2563-2572. Date of Electronic Publication: 2017 Jul 19.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE
مواضيع طبية MeSH: Antibodies, Neutralizing/*immunology , Marburg Virus Disease/*immunology , Marburgvirus/*immunology , Th1 Cells/*immunology, Adolescent ; Adult ; Animals ; Antibodies, Viral/immunology ; CD4-Positive T-Lymphocytes/immunology ; CD40 Ligand/metabolism ; CD8-Positive T-Lymphocytes/immunology ; Cytokines/metabolism ; Female ; Flow Cytometry ; Humans ; Immunity, Cellular/immunology ; Male ; Marburg Virus Disease/mortality ; Middle Aged ; Survivors ; Uganda/epidemiology ; Young Adult