المؤلفون: Jang-June Park, Emily P. Thi, Victor H. Carpio, Yingzhi Bi, Andrew G. Cole, Bruce D. Dorsey, Kristi Fan, Troy Harasym, Christina L. Iott, Salam Kadhim, Jin Hyang Kim, Amy C. H. Lee, Duyan Nguyen, Bhavna S. Paratala, Ruiqing Qiu, Andre White, Damodharan Lakshminarasimhan, Christopher Leo, Robert K. Suto, Rene Rijnbrand, Sunny Tang, Michael J. Sofia, Chris B. Moore

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/cbf4ada82c004c6dad7c4c374ea066bb

المؤلفون: Fabiola, G. Felcy, Damodharan, Lakshminarasimhan, Pattabhi, Vasantha, Nagarajan, Kuppuswamy

المصدر: Current Science, 2001 Jan 01. 80(1), 26-34.

URL الوصول: https://www.jstor.org/stable/24105551

المؤلفون: Sunny Tang, Jang-June Park, Rene Rijnbrand, Jin Hyang Kim, Troy Harasym, Robert K. Suto, Andrew G. Cole, André O. White, Amy C.H. Lee, Bhavna S. Paratala, Damodharan Lakshminarasimhan, Kristi Fan, Duyan Nguyen, Christopher Leo, Victor H. Carpio, Emily P. Thi, Ruiqing Qiu, Christina L Iott, Michael J. Sofia, Bruce D. Dorsey, Bi Yingzhi, Chris B. Moore, Salam Kadhim

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: 0301 basic medicine, Hepatitis B virus, Science, T cell, media_common.quotation_subject, Programmed Cell Death 1 Receptor, General Physics and Astronomy, Translational immunology, Antineoplastic Agents, CHO Cells, Endocytosis, Antiviral Agents, General Biochemistry, Genetics and Molecular Biology, Article, B7-H1 Antigen, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Cricetulus, medicine, Animals, Humans, Antigen-presenting cell, Internalization, Immune Checkpoint Inhibitors, B cell, media_common, Cancer, Cell Proliferation, Multidisciplinary, Chemistry, General Chemistry, Ligand (biochemistry), Small molecule, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Humanized mouse, Cancer research, Tumour immunology, Female, Immunotherapy, Protein Multimerization, Colorectal Neoplasms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ce17e3a072aebae4b4f96e103afe18
http://europepmc.org/articles/PMC7900207

المؤلفون: Van Phung, Higbee Jared Martin, Marilyn Wang, Rowena Suriben, Yan Wang, Dina A. Ayupova, Diana Li, Hung-I Harry Chen, Subhash D. Katewa, André O. White, Zhengyu Gao, Michele McEntee, Andrea Olland, Damodharan Lakshminarasimhan, Richard Ventura, Michael Chen, Julie Oeffinger, Jie Tang, Shelley R. Starck, Jer-Yuan Hsu, Darrin A. Lindhout, Pranali Taskar, Kalyani Mondal, Mark J. Solloway, Raj Haldankar, Avantika Kekatpure, Bernard B. Allan, Betty Chan Li

المصدر: Nature medicine. 26(8)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Cachexia, Glial Cell Line-Derived Neurotrophic Factor Receptors, Growth Differentiation Factor 15, Adipose tissue, Crystallography, X-Ray, Proto-Oncogene Mas, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Lipid oxidation, Weight loss, Internal medicine, Cell Line, Tumor, Neoplasms, Weight Loss, medicine, Glial cell line-derived neurotrophic factor, Animals, Humans, Muscle, Skeletal, biology, business.industry, Proto-Oncogene Proteins c-ret, Skeletal muscle, Antibodies, Monoclonal, Lipid metabolism, General Medicine, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Adipose Tissue, 030220 oncology & carcinogenesis, Multiprotein Complexes, Adipose triglyceride lipase, biology.protein, Heterografts, Lipid Peroxidation, medicine.symptom, business, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6269b35aef81f42e7c7d2627e1afde
https://pubmed.ncbi.nlm.nih.gov/32877689

المؤلفون: Kalyani Mondal, Geoffrey Horner, Manuel E. Lopez, Mark J. Solloway, Chen M, Laird T, Gao Z, Raj Haldankar, Andre White, Yao J, Wang M, Tang J, Avantika Kekatpure, Hugo Matern, Bernard B. Allan, Chan J, Alice Chen Y, Dina A. Ayupova, Higbee Jared Martin, Damodharan Lakshminarasimhan, Li B, Tian H, To C, Hsu Jy, Alan Kutach, Tom Parsons, Wang Sp, Shen Wd, Suzanne Christine Crawley, Joo W, Junming Yie, Darrin A. Lindhout, cEntee M, Fu D

المصدر: Nature. 550:255-259

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Glial Cell Line-Derived Neurotrophic Factor Receptors, Growth Differentiation Factor 15, Biology, Body weight, Amygdala, Eating, Mice, 03 medical and health sciences, 0302 clinical medicine, Weight loss, Neurotrophic factors, Internal medicine, medicine, Glial cell line-derived neurotrophic factor, Animals, Homeostasis, Receptor, Insulin-like growth factor 1 receptor, Mice, Knockout, Neurons, Multidisciplinary, Body Weight, Central Amygdaloid Nucleus, Area postrema, Feeding Behavior, Parabrachial Nucleus, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Hypothalamus, biology.protein, Female, Brainstem, GDF15, medicine.symptom, Energy Metabolism, Neuroscience, Stress, Psychological, 030217 neurology & neurosurgery, Brain Stem

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a4a24186b546405f4cc938c49643d3
https://doi.org/10.1038/nature24042

المؤلفون: Damodharan Lakshminarasimhan, Hwai-Chen Guo, Suchita Pande

المصدر: Molecular Genetics and Metabolism. 121:150-156

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Glycan, Stereochemistry, Endocrinology, Diabetes and Metabolism, Mutant, Chitobiose, Crystallography, X-Ray, Disaccharides, Biochemistry, Article, Substrate Specificity, Amidase, 03 medical and health sciences, chemistry.chemical_compound, Endocrinology, Aspartic acid, Genetics, Humans, Molecular Biology, chemistry.chemical_classification, biology, Chemistry, Hydrolysis, Glycopeptides, Wild type, Aspartylglucosylaminase, Substrate (chemistry), Aspartylglucosaminuria, 030104 developmental biology, Enzyme, Mutation, Biocatalysis, biology.protein, Mutant Proteins, Asparagine, Crystallization, Lysosomes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f356ef8117944ed4a0737ea7b674d821
https://doi.org/10.1016/j.ymgme.2017.04.008

المؤلفون: Stacia Kargman, Andrew John Jennings, Michael Miller, Andrew Stamford, Damodharan Lakshminarasimhan, Lewis C. Cantley, Anita D. Robin, Mayako Michino, David J. Huggins, Jiayi Xu, Edouard Mullarky, Andrea Olland, Daisuke Tomita, Naoyoshi Noguchi, Guoan Zhang, Peter T. Meinke, Taojunfeng Su

المصدر: Bioorg Med Chem Lett

مصطلحات موضوعية: Indoles, Clinical Biochemistry, Pharmaceutical Science, Dehydrogenase, Molecular Dynamics Simulation, Crystallography, X-Ray, 01 natural sciences, Biochemistry, Article, Serine, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, Humans, Phosphoglycerate dehydrogenase, Enzyme Inhibitors, Molecular Biology, Phosphoglycerate Dehydrogenase, Cell Proliferation, chemistry.chemical_classification, Indole test, Binding Sites, 010405 organic chemistry, Organic Chemistry, Oxidoreductase inhibitor, Amides, 0104 chemical sciences, Protein Structure, Tertiary, 010404 medicinal & biomolecular chemistry, Metabolic pathway, Enzyme, chemistry, Molecular Medicine, NAD+ kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f16e67aacdf7a18e54b2d994c08873d
https://pubmed.ncbi.nlm.nih.gov/31327531

المؤلفون: Damodharan, Lakshminarasimhan, Pattabhi, Vasantha ^∗, Behera, Manoranjan, Kotha, Sambasivarao

المصدر: In Journal of Molecular Structure 2004 705(1):101-106

المؤلفون: Kevin G. McLure, Reena G. Patel, Edward H. van der Horst, Henrik C. Hansen, S. David Brown, Olesya A. Kharenko, Damodharan Lakshminarasimhan, Bryan Cordell Duffy, Cyrus Calosing, Douglas B. Kitchen, Peter Young, André O. White, Robert K. Suto

المصدر: Journal of medicinal chemistry. 61(18)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, BRD4, Protein Conformation, Antineoplastic Agents, Cell Cycle Proteins, Crystallography, X-Ray, 01 natural sciences, 03 medical and health sciences, Structure-Activity Relationship, Protein structure, Methionine, Drug Discovery, Tumor Cells, Cultured, Humans, Transcription factor, Molecular Structure, 010405 organic chemistry, Drug discovery, Chemistry, Nuclear Proteins, Small molecule, 0104 chemical sciences, Bromodomain, 030104 developmental biology, Biochemistry, Acetylation, Covalent bond, Drug Design, Hematologic Neoplasms, Molecular Medicine, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9d24506cf927e32f035a3e7ad229c3
https://pubmed.ncbi.nlm.nih.gov/30165024

المؤلفون: Morgan Back, Matthew B. Robers, Edward M. Scolnick, Adam J. Stein, Jennifer Gale, Lina Benajiba, Damodharan Lakshminarasimhan, Arthur Campbell, Thomas Machleidt, Richard Stone, Florence F. Wagner, Xi Shi, Michael T. Hemann, Jennifer Wilkinson, Amy Saur Conway, Andrew L. Kung, Edward Holson, Joshua R. Sacher, Alexandre Puissant, Yan-Ling Zhang, Daniel J. DeAngelo, Yana Pikman, Ilene Galinsky, Linda Ross, Jen Q. Pan, Olivier Hermine, Kimberly Stegmaier, Gabriela Alexe, Taner Kaya, Michel Weiwer

المساهمون: Université Paris-Saclay, Laboratoire de chimie des Molécules bioactives et des aromes ( cnrs, umr 6001 ), Université Nice Sophia Antipolis ( UNS ), Université Côte d'Azur ( UCA ) -Université Côte d'Azur ( UCA ), Dana-Farber Cancer Institute [Boston], Computational Biology Center ( IBM T.J. Watson Research Center ), IBM, Centre de référence des mastocytoses, CHU Necker - Enfants Malades [AP-HP], Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Department of Pediatric Oncology [Boston, MA, USA]

المصدر: Science Translational Medicine
Science Translational Medicine, American Association for the Advancement of Science, 2018, 10 (431), 〈10.1126/scitranslmed.aam8460〉

مصطلحات موضوعية: 0301 basic medicine, Myeloid, animal structures, Biology, Article, [ SDV.CAN ] Life Sciences [q-bio]/Cancer, Glycogen Synthase Kinase 3, 03 medical and health sciences, GSK-3, medicine, Humans, Protein Isoforms, Enzyme Inhibitors, beta Catenin, Drug discovery, Kinase, Wnt signaling pathway, Myeloid leukemia, Dipeptides, U937 Cells, General Medicine, medicine.disease, 3. Good health, Leukemia, Myeloid, Acute, Leukemia, Haematopoiesis, 030104 developmental biology, medicine.anatomical_structure, Mutagenesis, Site-Directed, Cancer research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f26d3a8beef63982f0fc1f137af7cc
https://hal.archives-ouvertes.fr/hal-01815758