المؤلفون: Georgia Tsagkogeorga, Helena Santos-Rosa, Andrej Alendar, Dan Leggate, Oliver Rausch, Tony Kouzarides, Hendrik Weisser, Namshik Han

المصدر: Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3642

URL الوصول: https://doaj.org/article/396efec7513649209949c08bf1dc3e5d

المؤلفون: Eliza Yankova, Wesley Blackaby, Mark Albertella, Justyna Rak, Etienne Braekeleer, Georgia Tsagkogeorga, Ewa S. Pilka, Demetrios Aspris, Dan Leggate, Alan G. Hendrick, Natalie A. Webster, By

المصدر: Nature, Nature. 593(7860):597-601

الإتاحة: https://ideas.repec.org/a/nat/nature/v593y2021i7860d10.1038_s41586-021-03536-w.html

المؤلفون: Etienne De Braekeleer, Patrick Guest, Maria Eleftheriou, Georgia Tsagkogeorga, Ewa S. Pilka, Nerea Irigoyen, Malgorzata Gozdecka, Tony Kouzarides, Binje Vick, Andrew J. Bannister, Richard Fosbeary, Mark Albertella, Justyna Rak, Alan G. Hendrick, Irmela Jeremias, Dan Leggate, Demetrios Aspris, George S. Vassiliou, Eliza Yankova, Oliver Rausch, Natalie A. Webster, Konstantinos Tzelepis, Byron Andrews, João Lopes Dias, Wesley Blackaby

المساهمون: Yankova, Eliza [0000-0003-2913-0012], Pilka, Ewa S [0000-0002-0107-2597], Hendrick, Alan G [0000-0002-8604-0462], Irigoyen, Nerea [0000-0001-6346-3369], Dias, Joao ML [0000-0002-8451-3537], Bannister, Andrew J [0000-0002-6312-4436], Vick, Binje [0000-0003-1956-2778], Jeremias, Irmela [0000-0003-1773-7677], Vassiliou, George S [0000-0003-4337-8022], Rausch, Oliver [0000-0003-4074-3848], Tzelepis, Konstantinos [0000-0002-4865-7648], Kouzarides, Tony [0000-0002-8918-4162], Apollo - University of Cambridge Repository

المصدر: Nature 593, 597-601 (2021)
Nature

مصطلحات موضوعية: Methyltransferase, Adenosine, Antineoplastic Agents, Apoptosis, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, Cell Line, Tumor, Animals, Humans, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, Molecular Structure, Gene Expression Regulation, Leukemic, RNA, Cell Differentiation, Methyltransferases, Small molecule, Xenograft Model Antitumor Assays, 3. Good health, Mice, Inbred C57BL, Leukemia, Myeloid, Acute, Enzyme, chemistry, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Female, Stem cell

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d210f07dd025da467c48c4ac96a2015
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61877

المؤلفون: Hendrik Weisser, Adrián Bazaga, Dan Leggate

المساهمون: Apollo - University of Cambridge Repository

المصدر: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Computer science, Drug target, Gene regulatory network, lcsh:Medicine, Genome-wide association study, Genomics, Computational intelligence, Feature selection, medicine.disease_cause, Medical Oncology, Genome, Models, Biological, Article, Machine Learning, Drug Development, Interaction network, 631/67/68, Internal medicine, Neoplasms, Gene expression, Databases, Genetic, Drug Discovery, medicine, Humans, Gene Regulatory Networks, lcsh:Science, Gene, Cancer genetics, Mutation, Multidisciplinary, Drug discovery, Genome, Human, lcsh:R, 631/114/1305, Random forest, Neoplasm Proteins, ComputingMethodologies_PATTERNRECOGNITION, Drug development, 631/114/2401, lcsh:Q, Data integration, Genome-Wide Association Study

وصف الملف: application/pdf; text/xml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0f0a13eb8277afb90af9dcc86e4de2
http://europepmc.org/articles/PMC7330039

المؤلفون: George S. Vassiliou, Eliza Yankova, Etienne De Braekeleer, Oliver Rausch, Yaara Ofir-Rosenfeld, Richard Fosbeary, Alexandra Sapetschnig, Mark Albertella, Tony Kouzarides, Dan Leggate, Demetrios Aspris, Alan G. Hendrick, Cristina Pina, Konstantinos Tzelepis, Ana Filipa Domingues, Justyna Rak, Wesley Blackaby

المصدر: Blood. 134:403-403

مصطلحات موضوعية: 0301 basic medicine, Myeloid, Methyltransferase, Chemistry, Immunology, RNA, Myeloid leukemia, Cell Biology, Hematology, medicine.disease, Biochemistry, Transplantation, 03 medical and health sciences, Haematopoiesis, Leukemia, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, In vivo, medicine, Cancer research, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cad2a8c3b3a4c7a25f2b1f2eaaed797f
https://doi.org/10.1182/blood-2019-127962

المؤلفون: Gill Matthew Iain Andrew, Nigel Ramsden, Steve Price, Christopher Higgs, Richard Hale, Dennis Norman, Dan Leggate, Hazel Joan Dyke, Soraya S. Porres, Raffaella Mangano, Pascal Savy, Alison Jones, Francis Xavier Wilson, Peter Lockey, Neil Jennings, David E. Clark, Sue Cramp, Marie Andersson

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:2516-2519

مصطلحات موضوعية: Clinical Biochemistry, Histamine Antagonists, Biological Availability, Pharmaceutical Science, Pharmacology, Biochemistry, Receptors, G-Protein-Coupled, Inhibitory Concentration 50, Drug Discovery, Animals, Inverse agonist, Potency, Histamine H4 receptor, Molecular Biology, IC50, Receptors, Histamine H4, Virtual screening, Chemistry, Organic Chemistry, Stereoisomerism, Hit to lead, Ligand (biochemistry), Rats, Macaca fascicularis, Receptors, Histamine, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd703160124379248489a945072de4a
https://doi.org/10.1016/j.bmcl.2010.02.097