المؤلفون: Claire Palles, Susan Fotheringham, Laura Chegwidden, Marie Lucas, Rachel Kerr, Guy Mozolowski, Dan Rosmarin, Jenny C. Taylor, Ian Tomlinson, David Kerr

المصدر: Cancers, Vol 13, Iss 7, p 1497 (2021)

مصطلحات موضوعية: pharmacogenetics, dihydropyrimidine dehydrogenase, 5-FU, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6694/13/7/1497; https://doaj.org/toc/2072-6694

URL الوصول: https://doaj.org/article/0b88da015cf04c9ca51a4e33d6363066

المؤلفون: Jeremy P. Cheadle, Richard Kaplan, Angela Meade, Hannah West, Shelley Idziaszczyk, Polly A. Newcomb, Ulrike Peters, Andrew T. Chan, David Kerr, Dan Rosmarin, Ian Tomlinson, Matthew Seymour, Susan Richman, Amanda I. Phipps, Timothy S. Maughan, Rebecca Harris, David Fisher, Christopher G. Smith

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53fd4f4f1036ea7e8809f5c23e5c354c
https://doi.org/10.1158/1078-0432.22455930.v1

المؤلفون: Jeremy P. Cheadle, Richard Kaplan, Angela Meade, Hannah West, Shelley Idziaszczyk, Polly A. Newcomb, Ulrike Peters, Andrew T. Chan, David Kerr, Dan Rosmarin, Ian Tomlinson, Matthew Seymour, Susan Richman, Amanda I. Phipps, Timothy S. Maughan, Rebecca Harris, David Fisher, Christopher G. Smith

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54af31e9da1e28e4ca8018c9f660b5c
https://doi.org/10.1158/1078-0432.c.6523161.v1

المؤلفون: Christopher Smith, Shelley Idziaszczyk, Rebecca Harris, Ulrike Peters, David J. Kerr, Hannah West, Richard Kaplan, Tim Maughan, Angela M. Meade, Matthew T. Seymour, Dan Rosmarin, Ian Tomlinson, Amanda I. Phipps, David Fisher, Andrew T. Chan, Jeremy Peter Cheadle, Susan D. Richman, Polly A. Newcomb

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Adolescent, Genotype, Colorectal cancer, Single-nucleotide polymorphism, Genome-wide association study, Bioinformatics, Polymorphism, Single Nucleotide, Article, RC0254, Antigens, CD, Internal medicine, Biomarkers, Tumor, medicine, Humans, Genetic Predisposition to Disease, Survival analysis, Aged, Neoplasm Staging, Proportional Hazards Models, Aged, 80 and over, Clinical Trials as Topic, Cetuximab, Proportional hazards model, business.industry, Middle Aged, Cadherins, Prognosis, medicine.disease, Minor allele frequency, Meta-analysis, Female, Colorectal Neoplasms, business, Genome-Wide Association Study, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfbd7530a303d5c7d6f214d029ff1f8a

المؤلفون: Dan Rosmarin, Rachel Kerr, Claire Palles, Ian Tomlinson, David J. Kerr, Enric Domingo, Kevin Maskell, David N. Church

المصدر: Nature reviews. Cancer. 14(6)

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Applied Mathematics, General Mathematics, Alternative medicine, Genetic variants, Cancer, Pharmacology, medicine.disease, Anticancer drug, Unmet needs, Clinical trial, Cancer Medicine, medicine, Adverse effect, Intensive care medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b007332cf7558a9aa4d75e75128db4
http://ora.ox.ac.uk/objects/uuid:0f63395f-f633-42bc-8a54-6541c3e34e5f

المؤلفون: Rosmarin D; Dan Rosmarin, Claire Palles, David Church, Enric Domingo, Angela Jones, Ian Tomlinson, Wellcome Trust Centre for Human Genetics, NIHR Comprehensive Biomedical Research Centre, University of Oxford; Dan Rosmarin, David Church, Elaine Johnstone, Haitao Wang, Sharon Love, Patrick Julier, Claire Scudder, George Nicholson, Rachel Midgley, David Kerr, and George Nicholson, University of Oxford, Oxford; Michael Braun, The Christie NHS Foundation Trust, Manchester; Matthew Seymour, St James's University Hospital, Leeds; Lindsay Thompson, Medical Research Council Clinical Trials Unit; Rohini Sharma, Imperial College Healthcare NHS Trust, Hammersmith and Charing Cross Hospitals, London, United Kingdom; Anna Gonzalez-Neira, Spanish National Cancer Research Centre; Miguel Martin, Instituto de Investigacion Sanitaria Hospital General Universitario Gregorio Marañón, Universidad Complutense, Madrid; Nuria Ribelles, Hospital Universitario Virgen de la Victoria, Málaga; Eva Martinez-Balibrea, Institut Català d'Oncologia, Institut de Recerca Sanitària Germans Trias i Pujol, Barcelona; Jesus Garcia-Foncillas, University Clinic of Navarra, University of Navarra, Pamplona, Spain; Daniel Sargent, Erin Green, Mayo Clinic, Rochester, MN; Howard McLeod, University of North Carolina, Chapel Hill, NC; Ulrich M. Zanger, Matthias Schwab, Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart; Ulrich M. Zanger, Matthias Schwab, University Hospital Tuebingenl, Tuebingen, Germany; Benjamin Lacas, Valérie Boige, Jean-Pierre Pignon, Institut Gustave Roussy, Villejuif; Marie-Christine Etienne-Grimaldi, Gérard Milano, Centre Antoine Lacassagne, Nice; Thierry Lecomte, Pierre Laurent-Puig, Assistance Publique Hopitaux de Paris, Hopital Européen Georges Pompidou, Paris; Alain Morel, Institut National de la Sante et de la Recherche Medicale U564, Centre Paul Papin, Angers, France; Shoaib Afzal, Henrik Enghusen, Laboratory of Clinical Pharmacology, Rigshospitalet, Copenhagen; Sør, Palles C, Church D, Domingo E, Jones A, Johnstone E, Wang H, Love S, Julier P, Scudder C, Nicholson G, Gonzalez-Neira A, Martin M, Sargent D, Green E, McLeod H, Zanger UM, Schwab M, Braun M, Seymour M, Thompson L, Lacas B, Boige V, Ribelles N, Afzal S, Enghusen H, Jensen SA, Etienne-Grimaldi MC, Milano G, Wadelius M, Glimelius B, Garmo H, Gusella M, Lecomte T, Laurent-Puig P, Martinez-Balibrea E, Sharma R, Garcia-Foncillas J, Kleibl Z, Morel A, Pignon JP, Midgley R, Kerr D, Tomlinson I

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2014 Apr 01; Vol. 32 (10), pp. 1031-9. Date of Electronic Publication: 2014 Mar 03.

نوع المنشور: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review; Systematic Review

بيانات الدورية: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Combined Chemotherapy Protocols/*adverse effects , Colorectal Neoplasms/*drug therapy , Deoxycytidine/*analogs & derivatives , Dihydrouracil Dehydrogenase (NADP)/*genetics , Fluorouracil/*adverse effects , Fluorouracil/*analogs & derivatives , Thymidylate Synthase/*genetics, Capecitabine ; Deoxycytidine/administration & dosage ; Deoxycytidine/adverse effects ; Drug-Related Side Effects and Adverse Reactions/genetics ; Fluorouracil/administration & dosage ; Genetic Markers ; Humans ; Polymorphism, Genetic ; Predictive Value of Tests