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1
المؤلفون: Maria Suprun, Daniel P. Dickstein, Xiangyu Peng, Kunal Malik, Benjamin Ungar, Emma Guttman-Yassky, Tord Labuda, Dan Todd, Mayte Suárez-Fariñas, Margeaux Oliva, Yeriel Estrada, Robert Bissonnette, Hui Xu
المصدر: Journal of Allergy and Clinical Immunology.
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Administration, Topical, Immunology, Anti-Inflammatory Agents, Betamethasone dipropionate, Betamethasone, Tacrolimus, Dermatitis, Atopic, 030207 dermatology & venereal diseases, 03 medical and health sciences, Pimecrolimus, Young Adult, 0302 clinical medicine, Psoriasis, Medicine, Potency, Humans, Immunology and Allergy, Aged, Skin, Transepidermal water loss, Clobetasol, Hyperplasia, business.industry, Cell Differentiation, Atopic dermatitis, Middle Aged, medicine.disease, Placebo Effect, Dermatology, 030104 developmental biology, Cytokines, Female, Clobetasol propionate, business, Biomarkers, medicine.drug
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2
المؤلفون: Pat Wheelan, Dan Todd, Rob Ferris, Matt Tallant, Zhiping Xiong, Jung Ho Jun, Wieslaw M. Kazmierski, Maosheng Duan, Mark P. Edelstein
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:6381-6385
مصطلحات موضوعية: Anti-HIV Agents, Chemistry, Organic Chemistry, Clinical Biochemistry, Antagonist, Pharmaceutical Science, Biochemistry, Intestinal fluid, chemistry.chemical_compound, Pharmacokinetics, CCR5 Receptor Antagonists, Drug Discovery, HIV-1, Urea, Molecular Medicine, Moiety, Molecular Biology
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3
المؤلفون: Harry B. Marr, Kevin P. Madauss, Jonathan Y. Bass, Shawn P. Williams, Dan Todd, Paul Kenneth Spearing, Adwoa Akwabi-Ameyaw, Lihong Chen, Robert B. McFadyen, Justin A. Caravella, Derek J. Parks, Frank Navas, David N. Deaton, Katrina L. Creech, G. Bruce Wisely, Richard Dana Caldwell, Aaron B. Miller
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:4733-4739
مصطلحات موضوعية: Agonist, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Receptors, Cytoplasmic and Nuclear, Pharmaceutical Science, Thiophenes, Naphthalenes, Crystallography, X-Ray, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Humans, Computer Simulation, Molecular Biology, Binding Sites, Organic Chemistry, Benzothiophene, Isoxazoles, Rats, Nuclear receptor, chemistry, Molecular Medicine, Farnesoid X receptor
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4
المؤلفون: Justin A. Caravella, David N. Deaton, Katrina L. Creech, G. Bruce Wisely, Jonathan Y. Bass, Lihong Chen, Harry B. Marr, Robert B. McFadyen, Shawn P. Williams, Richard Dana Caldwell, Kevin P. Madauss, Aaron B. Miller, Derek J. Parks, Dan Todd
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:2969-2973
مصطلحات موضوعية: Agonist, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Receptors, Cytoplasmic and Nuclear, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Fluorescence Resonance Energy Transfer, medicine, Animals, Structure–activity relationship, Isoxazole, Molecular Biology, Aryl, Organic Chemistry, Isoxazoles, G protein-coupled bile acid receptor, Rats, Nuclear receptor, chemistry, Molecular Medicine, Farnesoid X receptor
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5
المؤلفون: Lihong Chen, Jonathan Y. Bass, David N. Deaton, Aaron B. Miller, Justin A. Caravella, Istvan Kaldor, Robert B. McFadyen, Stacey A. Jones, Dan Todd, Paul Kenneth Spearing, Kevin P. Madauss, Adwoa Akwabi-Ameyaw, Derek J. Parks, Richard Dana Caldwell, Frank Navas, Yaping Liu, Katrina L. Creech, G. Bruce Wisely, Harry B. Marr, Shawn P. Williams
المصدر: Bioorganic & Medicinal Chemistry Letters. 18:4339-4343
مصطلحات موضوعية: Agonist, Molecular model, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Carboxylic Acids, Molecular Conformation, Administration, Oral, Receptors, Cytoplasmic and Nuclear, Pharmaceutical Science, Naphthalenes, Crystallography, X-Ray, Biochemistry, Chemical synthesis, Mice, Structure-Activity Relationship, Dogs, Drug Discovery, medicine, Animals, Structure–activity relationship, Receptor, Molecular Biology, Cholestasis, Molecular Structure, Chemistry, Stomach, Organic Chemistry, Haplorhini, Isoxazoles, G protein-coupled bile acid receptor, Rats, DNA-Binding Proteins, Disease Models, Animal, Nuclear receptor, Gastric Mucosa, Molecular Medicine, Farnesoid X receptor, Transcription Factors
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6
المؤلفون: John W. Seal, Dan Todd, Banka Anna L, Luz H. Carballo, Zhiping Xiong, Lisa L. Stroup, Amanda Mathis, Zhi Hong, Jeffery J. Pouliot, Pek Yoke Chong, Michael Youngman, Robert Hamatake, Daniel J. Price, Jing Fang, Katrina L. Creech, Andrew Spaltenstein, John G. Catalano, Christopher Don Roberts, J. Brad Shotwell, Andrew J. Peat, Vincent W.-F. Tai, John F. Miller, Sylvia Furst, Huichang Zhang
المصدر: Journal of medicinal chemistry. 57(5)
مصطلحات موضوعية: Ligand efficiency, Chemistry, Viral nonstructural protein, viruses, Hepatitis C virus, Hepacivirus, Viral Nonstructural Proteins, medicine.disease_cause, Virus Replication, Virology, Small molecule, Antiviral Agents, Hepatitis C, In vitro, Disease Models, Animal, Mice, Viral replication, In vivo, Area Under Curve, Drug Discovery, medicine, Molecular Medicine, Potency, Animals, Prodrugs
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7
المؤلفون: Dan Todd, Benjamin Ungar, M. Suprun, Margeaux Oliva, Emma Guttman-Yassky, Tord Labuda, Robert Bissonnette, M. Suarez-Farinas
المصدر: Journal of Investigative Dermatology. 136:S96
مصطلحات موضوعية: medicine.medical_specialty, business.industry, Topical agents, Medicine, Cell Biology, Dermatology, Atopic dermatitis, business, medicine.disease, Molecular Biology, Biochemistry, Differential effects
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8
المؤلفون: Mark P. Edelstein, Pat Wheelan, Rob Ferris, Matt Tallant, Jung Ho Jun, Maosheng Duan, Wieslaw M. Kazmierski, Zhiping Xiong, Dan Todd
المصدر: ChemInform. 43
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Series (mathematics), Urea, virus diseases, General Medicine, Combinatorial chemistry
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9
المؤلفون: Aaron B. Miller, Harry B. Marr, Katrina L. Creech, G. Bruce Wisely, Shawn P. Williams, Adwoa Akwabi-Ameyaw, Lihong Chen, David N. Deaton, Justin A. Caravella, Paul Kenneth Spearing, Kevin P. Madauss, Derek J. Parks, Frank Navas, Dan Todd
المصدر: Bioorganicmedicinal chemistry letters. 21(20)
مصطلحات موضوعية: Agonist, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Molecular Sequence Data, Molecular Conformation, Pharmaceutical Science, Receptors, Cytoplasmic and Nuclear, Biochemistry, Cell Line, chemistry.chemical_compound, Drug Discovery, Stilbenes, medicine, Moiety, Animals, Humans, Carboxylate, Amino Acid Sequence, Molecular Biology, Indole test, Organic Chemistry, Benzothiophene, Isoxazoles, G protein-coupled bile acid receptor, chemistry, Molecular Medicine, Farnesoid X receptor, Transcription regulator
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10
المؤلفون: Justin A. Caravella, Terrence L. Smalley, Jonathan Y. Bass, Kevin P. Madauss, Aaron B. Miller, Robert B. McFadyen, Katrina L. Creech, G. Bruce Wisely, Harry B. Marr, Lihong Chen, Dan Todd, Shawn P. Williams, David N. Deaton, Paul Kenneth Spearing, Derek J. Parks, Frank Navas, Wendy Y. Mills
المصدر: Bioorganicmedicinal chemistry letters. 21(4)
مصطلحات موضوعية: Agonist, Blood Glucose, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Receptors, Cytoplasmic and Nuclear, Naphthalenes, Crystallography, X-Ray, Ligands, Weight Gain, Biochemistry, Chemical synthesis, Diabetes Mellitus, Experimental, chemistry.chemical_compound, Mice, Dogs, Drug Discovery, medicine, Fluorescence Resonance Energy Transfer, Animals, Humans, Receptor, Molecular Biology, Binding Sites, Bicyclic molecule, Chemistry, Organic Chemistry, Quinoline, Isoxazoles, G protein-coupled bile acid receptor, Protein Structure, Tertiary, Rats, Nuclear receptor, Quinolines, Molecular Medicine, Farnesoid X receptor