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1Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity
المؤلفون: Moonsoo M. Jin, Motomu Shimaoka, Yong Sung Kim, Nathan S. Astrof, Dane K. Wittrup, Timothy A. Springer, Christopher V. Carman, Gang Song
المصدر: Proceedings of the National Academy of Sciences. 103:5758-5763
مصطلحات موضوعية: Models, Molecular, Integrins, Saccharomyces cerevisiae Proteins, Molecular Sequence Data, Allosteric regulation, Intercellular Adhesion Molecule-1, Integrin, Mutant, Biology, Polymerase Chain Reaction, Protein Structure, Secondary, Protein structure, Allosteric Regulation, Amino Acid Sequence, Binding site, Binding Sites, Multidisciplinary, Proteins, Biological Sciences, Surface Plasmon Resonance, Ligand (biochemistry), Directed evolution, Recombinant Proteins, Cell biology, Kinetics, Solubility, biology.protein, Directed Molecular Evolution
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d8c8c2a871ce540e47dfb7c1fff00f
https://doi.org/10.1073/pnas.0601164103