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المؤلفون: Himanshu Khandelia, Daniel Wuestner, Vikas Dubey, Behruz Bozorg
المصدر: PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 10, p e1007554 (2020)
Dubey, V, Bozorg, B, Wüstner, D & Khandelia, H 2020, ' Cholesterol binding to the sterol-sensing region of Niemann Pick C1 protein confines dynamics of its N-terminal domain ', PloS Computational Biology, vol. 16, no. 10, e1007554 . https://doi.org/10.1371/journal.pcbi.1007554مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Cell Membranes, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, hemic and lymphatic diseases, Biochemical Simulations, Electrochemistry, Salt Bridges, Biology (General), Lipid bilayer, Ecology, Chemistry, Cholesterol binding, Intracellular Signaling Peptides and Proteins, Niemann-Pick Disease, Type C, Lipids, Transmembrane protein, Cell biology, Sterols, Cholesterol, Computational Theory and Mathematics, Modeling and Simulation, Physical Sciences, lipids (amino acids, peptides, and proteins), Cellular Structures and Organelles, Research Article, Protein Binding, congenital, hereditary, and neonatal diseases and abnormalities, QH301-705.5, Protein domain, Allosteric regulation, 03 medical and health sciences, Cellular and Molecular Neuroscience, Protein Domains, Niemann-Pick C1 Protein, Genetics, Humans, Molecular Biology, Ecology, Evolution, Behavior and Systematics, nutritional and metabolic diseases, Biology and Life Sciences, Computational Biology, Membrane Proteins, Cell Biology, Sterol, nervous system diseases, 030104 developmental biology, Algebra, Membrane protein, Linear Algebra, Niemann pick c1, Biophysics, NPC1, Lysosomes, Eigenvectors, 030217 neurology & neurosurgery, Mathematics
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