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المؤلفون: Peng Gao, Paolo Vincetti, Fabio Maria Sabbatini, Holly J. Carlisle, Luisa Mengatto, Stéphane De Lombaert, Anna Sava, Kerry Zobel, Xinying Liu, Claudia Beato, Jessica M. Bright, Alyssa M. A. Toda, Elena Serra, Federica Budassi, Marco Migliore, Laura Caberlotto, Cristiana Griffante, Silvia Bernardi, Mingliang Zhang, Albert W. Garofalo, Daniele Andreotti
المصدر: Journal of Medicinal Chemistry. 63:14821-14839
مصطلحات موضوعية: Indazoles, Tetrazoles, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, 01 natural sciences, Small Molecule Libraries, Mice, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, Animals, Humans, Kinase activity, Protein Kinase Inhibitors, Gene, 030304 developmental biology, 0303 health sciences, Molecular Structure, Chemistry, Kinase, Highly selective, LRRK2, High-Throughput Screening Assays, nervous system diseases, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, HEK293 Cells, Pyrimidines, Mutation, Cancer research, Molecular Medicine
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المؤلفون: Pan F. Chan, Kaushik Raha, Shruti Jain, Geoffrey Quinque, Margarete Neu, Daniele Andreotti, Roberto Profeta, Reema K. Thalji, Brian Donovan, Simona Tommasi, Lynn McCloskey, Christopher J. Nixon, Giovanni Meneghelli, Tania Bakshi, Anna Checchia, Robert A. Stavenger, Benjamin D. Bax, Alison Howells, Federica Tonelli, Haifeng Cui
المصدر: Bioorganic & Medicinal Chemistry Letters. 29:1407-1412
مصطلحات موضوعية: Acinetobacter baumannii, Models, Molecular, medicine.drug_class, Clinical Biochemistry, Antibiotics, Pharmaceutical Science, Microbial Sensitivity Tests, Isomerase, Crystallography, X-Ray, 01 natural sciences, Biochemistry, DNA gyrase, Cell Line, Mice, Structure-Activity Relationship, Drug Discovery, Escherichia coli, medicine, Animals, Humans, Topoisomerase II Inhibitors, Molecular Biology, Ion channel, Mice, Knockout, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Chemistry, Topoisomerase, Organic Chemistry, Biochemical Activity, Anti-Bacterial Agents, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Ion channel activity, DNA Gyrase, Drug Design, biology.protein, Molecular Medicine, Antibacterial activity
وصف الملف: application/pdf
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المؤلفون: Paul Bamborough, Oliver James Philps, Jia-Ning Xiang, Andrew John Eatherton, Pamela Dossang, Yi Li, Cheng Peng, Paula L. Nichols, Kelly Dong, Xuedong Dai, Xiao Ding, Lucy M. Mensah, Daniele Andreotti, Ming-Hsun Ho, Xiao-Ming Guan, Feng Ren, Colin Edge, Luigi Piero Stasi, Zehong Wan, Kai Long, Karamjit Singh Jandu, Alastair D. Reith
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:4034-4038
مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, High selectivity, Substituent, Administration, Oral, Pharmaceutical Science, Pharmacology, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Biochemistry, Cns penetration, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Humans, Kinome, Protein Kinase Inhibitors, Molecular Biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Kinase, Organic Chemistry, LRRK2, nervous system diseases, Bioavailability, 030104 developmental biology, Benzamides, Molecular Medicine
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المؤلفون: Daniele Donati, Stefano Biondi, Alfredo Paio, Stjepan Mutak, Sergio Lociuro, Elisa Piga, Francesca Cardullo, Dražen Pavlović, Daniele Andreotti
المصدر: ACS Medicinal Chemistry Letters. 5:1133-1137
مصطلحات موضوعية: chemistry.chemical_classification, medicine.drug_class, Stereochemistry, Organic Chemistry, Telithromycin, Erythromycin, Biology, Biochemistry, In vitro, Macrolide Antibiotics, Microbiology, chemistry, Clarithromycin, Drug Discovery, medicine, Antibacterial activity, Ketolide, Lactone, medicine.drug
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المؤلفون: Daniele Andreotti
المصدر: Infectious Disorders - Drug Targets. 16:217-218
مصطلحات موضوعية: Microbiology (medical), Pharmacology, Wound care, business.industry, Molecular Medicine, Medicine, General Medicine, business, Microbiology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dceb75ae5e176697fe666938014be43c
https://doi.org/10.2174/1871526516666160922093919 -
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المؤلفون: Daniele Andreotti, Roberto Profeta, Emanuele Miserazzi, Simone Spada, Arnaldo Nalin, Alfonso Pozzan
المصدر: Tetrahedron Letters. 51:6526-6530
مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, Organic Chemistry, Pyridine-N-oxide, Alcohol, Biochemistry, Hydrolysis, chemistry.chemical_compound, chemistry, Acyl chloride, Reagent, Drug Discovery, Pyridine, lipids (amino acids, peptides, and proteins), Stereoselectivity, Alkyl
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المصدر: European journal of organic chemistry
2011 (2011): 271–279. doi:10.1002/ejoc.201000936
info:cnr-pdr/source/autori:Massaro A.; Mordini A.; Mingardi A.; Klein J.; Andreotti D./titolo:A New Sequential Intramolecular Cyclization Based on the Boekelheide Rearrangement/doi:10.1002%2Fejoc.201000936/rivista:European journal of organic chemistry (Print)/anno:2011/pagina_da:271/pagina_a:279/intervallo_pagine:271–279/volume:2011
9th International Symposium on Carbanion Chemistry, ISCC-9, Firenze, Italy, 2010
info:cnr-pdr/source/autori:Massaro A., Mordini A., Mingardi A., Klein J., Andreotti D./congresso_nome:9th International Symposium on Carbanion Chemistry, ISCC-9/congresso_luogo:Firenze, Italy/congresso_data:2010/anno:2010/pagina_da:/pagina_a:/intervallo_pagineمصطلحات موضوعية: Intramolecular reaction, Stereochemistry, Nitrogen heterocycles, Organic Chemistry, Intramolecular cyclization, Pyridine N-oxides, Chemical synthesis, chemistry.chemical_compound, Synthetic methods, chemistry, Cyclization, Intramolecular force, Pyridine, Boekelheide rearrangement, Amine gas treating, Physical and Theoretical Chemistry, Trifluoromethanesulfonate
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المؤلفون: Daniele Andreotti, Roberto Profeta, Alfredo Paio, Simone Spada, Francesco Ferroni, Jens Klein
المصدر: Tetrahedron Letters. 51:5521-5524
مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Stereochemistry, Aryl, Organic Chemistry, Drug Discovery, Organic chemistry, Biochemistry, Octane
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المؤلفون: William Maton, Fernando Bravo, Paolo Stabile, Daniele Andreotti, Arnaldo Nalin, Simone Spada, Roberto Profeta, Alcide Perboni, Federica Stazi, Damiano Castoldi, Anna Mingardi, Stefano Provera, Emanuele Miserazzi, Nicola Giubellina, Mario Mattioli, Roberta Pachera, Pieter Westerduin, Arianna Ribecai, Simon M. Bryant, Lucilla Turco, Angelo M. Manzo
المصدر: Organic Process Research & Development. 14:1239-1247
مصطلحات موضوعية: chemistry.chemical_classification, Heptane, Organic Chemistry, Diastereomer, chemistry.chemical_compound, Hydrolysis, chemistry, Yield (chemistry), Organic chemistry, Epimer, Hydroxymethyl, Carboxylate, Physical and Theoretical Chemistry, Lactone
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المؤلفون: Stefania Contini, Emiliangelo Ratti, Aldo Feriani, Frank E. Blaney, David G. Trist, Karen L Roberts, Fabio Maria Sabbatini, Romano Di Fabio, Damiano Ghirlanda, Daniele Donati, Angela Worby, Stefano Provera, Mario Mattioli, Yves St-Denis, Roberto Arban, Elettra Fazzolari, Emiliano Castiglioni, Francesca Pavone, Simone Spada, Enza Di Modugno, Carla Marchioro, Giovanni Bernasconi, Arnaldo Nalin, Anna Mingardi, Anna Maria Capelli, Daniele Andreotti, Simone Braggio, Gabriella Gentile
المصدر: Journal of Medicinal Chemistry. 51:7370-7379
مصطلحات موضوعية: Male, Molecular model, Pyridines, Stereochemistry, Stereoisomerism, Motor Activity, Receptors, Corticotropin-Releasing Hormone, Chemical synthesis, Rats, Sprague-Dawley, chemistry.chemical_compound, In vivo, Forelimb, Drug Discovery, Animals, Humans, Moiety, Pyrroles, Ultrasonics, Receptor, Psychological Tests, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Aryl, In vitro, Rats, Models, Chemical, Exploratory Behavior, Molecular Medicine, Female, Vocalization, Animal, Gerbillinae
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