المؤلفون: Danielle C. Desravines, Itziar Serna Martin, Robert Schneider, Philippe J. Mas, Nataliia Aleksandrova, Malene Ringkjøbing Jensen, Martin Blackledge, Darren J. Hart

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/0b8d250e25a8437cb57a64f0045febb5

المؤلفون: Nataliia Aleksandrova, Danielle C. Desravines, Malene Ringkjøbing Jensen, Itziar Serna Martin, Robert Schneider, Martin Blackledge, Darren J. Hart, Philippe J. Mas

المساهمون: European Molecular Biology Laboratory [Grenoble] (EMBL), Institut de biologie structurale (IBS - UMR 5075 ), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Integrated Structural Biology Grenoble (ISBG - UMS 3518 ), Centre National de la Recherche Scientifique (CNRS)-European Molecular Biology Laboratory [Grenoble] (EMBL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-European Molecular Biology Laboratory [Grenoble] (EMBL)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])

المصدر: Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.3678. ⟨10.1038/s41598-017-03718-5⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, 2017, 7 (1), pp.3678. ⟨10.1038/s41598-017-03718-5⟩

مصطلحات موضوعية: 0301 basic medicine, Magnetic Resonance Spectroscopy, Stereochemistry, Science, Gene Expression, Plasma protein binding, Biology, 010402 general chemistry, 01 natural sciences, Histone Deacetylases, Article, 03 medical and health sciences, Structure-Activity Relationship, Humans, Nuclear Receptor Co-Repressor 2, Binding site, Zinc ion binding, Transcription factor, chemistry.chemical_classification, Alanine, Multidisciplinary, Binding Sites, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], 0104 chemical sciences, Amino acid, 030104 developmental biology, chemistry, Biochemistry, Solubility, Mutagenesis, Medicine, Corepressor, Alpha helix, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6371da38b4492ded074ba45ccbaa8241
https://hal.univ-grenoble-alpes.fr/hal-01561722

المؤلفون: Danielle C. Desravines, Darren J. Hart, Hayretin Yumerefendi

المصدر: Methods (San Diego, Calif.). 55(1)

مصطلحات موضوعية: Genetic Vectors, Green Fluorescent Proteins, Gene Expression, Computational biology, DNA Fragmentation, Biology, Bioinformatics, General Biochemistry, Genetics and Molecular Biology, Field (computer science), Genes, Reporter, Escherichia coli, Humans, Cloning, Molecular, Molecular Biology, Gene Library, Automation, Laboratory, Sequence, Deoxyribonucleases, A protein, Proteins, Construct (python library), Protein engineering, Expression (computer science), Directed evolution, High-Throughput Screening Assays, Solubility, Mutagenesis, Identification (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cc921a207eecd2367c0c6e7a34b503
https://pubmed.ncbi.nlm.nih.gov/21723393

المؤلفون: Michel Desmadril, Dominique Durand, Herman van Tilbeurgh, Asma Guellouz, Agathe Urvoas, Philippe Minard, Marc Graille, Marie Valerio-Lepiniec, Danielle C. Desravines

المساهمون: Institut de biochimie et biophysique moléculaire et cellulaire (IBBMC), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2010, 404, pp.307-327. ⟨10.1016/j.jmb.2010.09.048⟩

مصطلحات موضوعية: Models, Molecular, [SDV]Life Sciences [q-bio], Crystallography, X-Ray, Protein Engineering, 01 natural sciences, Pentapeptide repeat, Protein Structure, Secondary, DSC, X-Ray Diffraction, Structural Biology, Direct repeat, ComputingMilieux_MISCELLANEOUS, 0303 health sciences, RCA, Protein Stability, Circular Dichroism, Temperature, SAXS, Directed evolution, SEC, Recombinant Proteins, size-exclusion chromatography, differential scanning calorimetry, Dimerization, Repetitive Sequences, Amino Acid, Sequence analysis, Stereochemistry, Molecular Sequence Data, Protein design, TPR, Biology, 010402 general chemistry, Biophysical Phenomena, 03 medical and health sciences, Peptide Library, tetratricopeptide repeat, Scattering, Small Angle, Consensus sequence, Amino Acid Sequence, Protein Structure, Quaternary, Molecular Biology, 030304 developmental biology, 4-pentanediol, 0104 chemical sciences, Crystallography, Drug Design, small-angle X-ray scattering, Ankyrin repeat, MPD, 2-methyl-2, Alpha helix, rolling circle amplification

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5bcae7781ba071fdf8710e4683bd67b
https://hal.archives-ouvertes.fr/hal-03298539

المؤلفون: Gérard Simonneaux, Florence Demay, Elisa Sala, Vanessa Nardese, Andrea R. Beccari, Nataliia Aleksandrova, Soizic Chevance, Rémy Le Guével, Danielle C. Desravines, Daniele Carettoni, Aurélien Lecorgne, Frédérik Oger, Simone Lorenzi, Darren J. Hart, Peter Barath, Arnaud Bondon, Gilles Salbert

المساهمون: Interactions cellulaires et moléculaires (ICM), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS), Institut des Sciences Chimiques de Rennes (ISCR), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA), the Region Bretagne (SIE 211-B3-11), the Centre National pour la Recherche Scientifique, and the Ministre de l'Enseignement Supérieur et de la Recherche., European Project, Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2010, 53 (5), pp.1937-50. ⟨10.1021/jm901561u⟩
Journal of Medicinal Chemistry, 2010, 53 (5), pp.1937-50. ⟨10.1021/jm901561u⟩

مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, Molecular model, medicine.drug_class, Stereochemistry, Blotting, Western, Enzyme-Linked Immunosorbent Assay, Cell Growth Processes, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Hydroxamic Acids, 01 natural sciences, Histone Deacetylases, Mass Spectrometry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Amide, Drug Discovery, medicine, Humans, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], 030304 developmental biology, chemistry.chemical_classification, Vorinostat, 0303 health sciences, biology, 010405 organic chemistry, Histone deacetylase 2, Histone deacetylase inhibitor, HDAC7, Active site, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Hep G2 Cells, 3. Good health, 0104 chemical sciences, Histone Deacetylase Inhibitors, [SDV.BBM.BP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biophysics, Enzyme, Histone, Microscopy, Fluorescence, Biochemistry, chemistry, biology.protein, Molecular Medicine, Caco-2 Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d99a4afa39044345c0b9b79134f59b6
https://hal.archives-ouvertes.fr/hal-00462114