المؤلفون: Kwangjun Lee, Andrew D. Abell, Steven W. Polyak, Beatriz Blanco-Rodriguez, John B. Bruning, Danielle Cini, Grant W. Booker, Robert W. Milne, Benjamin Noll, Andrew J. Hayes, Andrew C Marshall, Ashleigh S. Paparella, Jiage Feng, Matthew C.J. Wilce, Jingxian Yu, William Tieu

المساهمون: Lee, Kwang Jun, Tieu, William, Blanco-Rodriguez, Beatriz, Paparella, Ashleigh S, Yu, Jingxian, Hayes, Andrew, Feng, Jiage, Marshall, Andrew C, Noll, Benjamin, Milne, Robert, Cini, Danielle, Wilce, Matthew CJ, Booker, Grant W, Bruning, John B, Polyak, Steven W, Abell, Andrew D

المصدر: ACS Chemical Biology. 14:1990-1997

مصطلحات موضوعية: pharmacokinetic profile, 0301 basic medicine, Staphylococcus aureus, medicine.drug_class, Antibiotics, Microbial Sensitivity Tests, Molecular Dynamics Simulation, Crystallography, X-Ray, medicine.disease_cause, 01 natural sciences, Biochemistry, metabolic stability, Microbiology, Mice, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Drug Stability, Biotin, medicine, Animals, Carbon-Nitrogen Ligases, Enzyme Inhibitors, chemistry.chemical_classification, Sulfonamides, DNA ligase, 010405 organic chemistry, molecular dynamics simulations, General Medicine, Phosphate, Anti-Bacterial Agents, Rats, 0104 chemical sciences, Sulfonamide, 030104 developmental biology, chemistry, Drug Design, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17972eb42541dd574d7fb900e1b5a4a3
https://doi.org/10.1021/acschembio.9b00463

المؤلفون: Steven W. Polyak, Sonali Deshmukh, Grant W. Booker, Andrew D. Abell, Zikai Feng, Andrew J. Hayes, Matthew C.J. Wilce, Ashleigh S. Paparella, Danielle Cini, Kwang J. Lee, Jiage Feng

المساهمون: Paparella, Ashleigh S, Lee, Kwang Jun, Hayes, Andrew J, Feng, Jiage, Feng, Zikai, Cini, Danielle, Deshmukh, Sonali, Booker, Grant W, Wilce, Matthew CJ, Polyak, Steven W, Abell, Andrew D

المصدر: ACS infectious diseases. 4(2)

مصطلحات موضوعية: 0301 basic medicine, inorganic chemicals, Models, Molecular, Staphylococcus aureus, Halogenation, enzyme inhibitor, Molecular Conformation, Biotin, Microbial Sensitivity Tests, Biology, medicine.disease_cause, Ligases, 03 medical and health sciences, chemistry.chemical_compound, Minimum inhibitory concentration, antibiotic, medicine, Humans, biotin protein ligase, Binding site, Enzyme Inhibitors, chemistry.chemical_classification, DNA ligase, Binding Sites, Dose-Response Relationship, Drug, Molecular Structure, Molecular biology, Anti-Bacterial Agents, 030104 developmental biology, Infectious Diseases, Biochemistry, chemistry, Enzyme inhibitor, biology.protein, Antibacterial activity, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd8141af481d9078bd05a9f48708682
https://pubmed.ncbi.nlm.nih.gov/29131575