المؤلفون: Daniels MJD; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom., Lefevre L; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom., Szymkowiak S; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom., Drake A; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom., McCulloch L; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom.; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, United Kingdom., Tzioras M; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom., Barrington J; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom., Dando OR; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, United Kingdom., He X; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, United Kingdom., Mohammad M; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom., Sasaguri H; Department of Neurology and Neurological Science, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako, Japan., Saito T; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako, Japan.; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan., Saido TC; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako, Japan., Spires-Jones TL; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom., McColl BW; UK Dementia Research Insitute at The University of Edinburgh, Edinburgh, United Kingdom.

المصدر: ELife [Elife] 2023 Dec 12; Vol. 12. Date of Electronic Publication: 2023 Dec 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/metabolism , Cystatins*/metabolism , Neurodegenerative Diseases*/pathology, Animals ; Female ; Humans ; Male ; Mice ; Amyloid beta-Peptides/genetics ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/metabolism ; Disease Models, Animal ; Mice, Transgenic ; Microglia/metabolism

المؤلفون: Tzioras M; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Daniels MJD; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Davies C; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Baxter P; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., King D; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., McKay S; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Varga B; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK., Popovic K; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Hernandez M; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Stevenson AJ; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Barrington J; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Drinkwater E; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Borella J; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Holloway RK; MRC Centre for Reproductive Health, the University of Edinburgh, Edinburgh EH16 4TJ, UK., Tulloch J; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Moss J; MRC Centre for Reproductive Health, the University of Edinburgh, Edinburgh EH16 4TJ, UK; The Roslin Institute, the Royal (Dick) School of Veterinary Studies, the University of Edinburgh, Edinburgh EH25 9RG, UK., Latta C; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Kandasamy J; Department of Clinical Neurosciences, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK., Sokol D; Department of Clinical Neurosciences, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK., Smith C; Centre for Clinical Brain Sciences, the University of Edinburgh, Edinburgh EH16 4SB, UK., Miron VE; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; MRC Centre for Reproductive Health, the University of Edinburgh, Edinburgh EH16 4TJ, UK; Barlo Multiple Sclerosis Centre at St. Michael's Hospital, Keenan Research Centre for Biomedical Science, Toronto, ON M5B 1T8, Canada., Káradóttir RT; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK., Hardingham GE; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK., Henstridge CM; Division of Systems Medicine, School of Medicine, University of Dundee, Dundee DD1 9SY, UK., Brennan PM; Department of Clinical Neurosciences, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK; Centre for Clinical Brain Sciences, the University of Edinburgh, Edinburgh EH16 4SB, UK., McColl BW; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK. Electronic address: barry.mccoll@ed.ac.uk., Spires-Jones TL; UK Dementia Research Institute, the University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Discovery Brain Sciences, the University of Edinburgh, Edinburgh EH8 9JZ, UK. Electronic address: tara.spires-jones@ed.ac.uk.

المصدر: Cell reports. Medicine [Cell Rep Med] 2023 Sep 19; Vol. 4 (9), pp. 101175. Date of Electronic Publication: 2023 Aug 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease* , Microglia*, Animals ; Humans ; Mice ; Astrocytes ; Eating ; Synapses

المؤلفون: McCulloch L; Centre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK., Harris AJ; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK., Malbon A; Easter Bush Pathology, The Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Edinburgh, UK., Daniels MJD; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK., Younas M; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Group, University of Manchester, Manchester, UK., Grainger JR; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Group, University of Manchester, Manchester, UK.; Lydia Becker Institute of Immunology and Inflammation, Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Allan SM; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Group, University of Manchester, Manchester, UK., Smith CJ; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Group, University of Manchester, Manchester, UK.; Greater Manchester Comprehensive Stroke Centre, Manchester Centre for Clinical Neurosciences, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford, UK.; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., McColl BW; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.

المصدر: Immunology [Immunology] 2022 Dec; Vol. 167 (4), pp. 558-575. Date of Electronic Publication: 2022 Aug 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0374672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2567 (Electronic) Linking ISSN: 00192805 NLM ISO Abbreviation: Immunology Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Infections* , Stroke*/complications , Stroke*/therapy, Mice ; Animals ; Immunoglobulins, Intravenous/therapeutic use ; Immunologic Factors ; Immunoglobulin M ; Bacteria ; Lung

المؤلفون: Rivers-Auty J; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom.; Tasmanian School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania 7000, Australia., Tapia VS; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., White CS; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., Daniels MJD; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., Drinkall S; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., Kennedy PT; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., Spence HG; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., Yu S; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., Green JP; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., Hoyle C; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., Cook J; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., Bradley A; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., Mather AE; Quadram Institute Bioscience, Norwich NR4 7UA, United Kingdom.; University of East Anglia, Norwich NR4 7TJ, United Kingdom., Peters R; School of Psychology, University of New South Wales, Sydney, New South Wales 2052, Australia.; Neuroscience Research Australia, Sydney, New South Wales 2031, Australia., Tzeng TC; Immunology and Inflammation, Bristol-Myers Squibb (Celgene Corporation), Cambridge, Massachusetts 02140., Gordon MJ; Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen AB25 2ZD, United Kingdom., Beattie JH; Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen AB25 2ZD, United Kingdom., Brough D; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom Catherine.lawerence@manchester.ac.uk David.brough@manchester.ac.uk.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom., Lawrence CB; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, United Kingdom Catherine.lawerence@manchester.ac.uk David.brough@manchester.ac.uk.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom.

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Mar 31; Vol. 41 (13), pp. 3025-3038. Date of Electronic Publication: 2021 Feb 17.

نوع المنشور: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Disease Progression*, Alzheimer Disease/*blood , Cognitive Dysfunction/*blood , NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism , Zinc/*blood, Adult ; Aged ; Alzheimer Disease/diagnostic imaging ; Alzheimer Disease/diet therapy ; Animals ; Cells, Cultured ; Cognitive Dysfunction/diagnostic imaging ; Cognitive Dysfunction/diet therapy ; Dietary Supplements ; Female ; Follow-Up Studies ; Humans ; Inflammation Mediators/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Middle Aged ; Zinc/administration & dosage ; Zinc/deficiency

المؤلفون: Tapia VS; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, United Kingdom., Daniels MJD; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, United Kingdom; UK Dementia Research Institute, University of Edinburgh, College of Medicine and Veterinary Medicine, 49 Little France Crescent, Edinburgh EH16 4SB, Scotland, United Kingdom., Palazón-Riquelme P; Division of Infection, Immunity, and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Collaborative Centre of Inflammation Research, Manchester Academic Health Science Centre, Core Technology Facility, University of Manchester, Manchester M13 9PT, United Kingdom; International Centre for Infectiology Research, INSERM U1111, CNRS UMR5308, École Normale Supérieure de Lyon, Claude Bernard Lyon 1 University, 69100 Lyon, France., Dewhurst M; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, United Kingdom; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Department of Biochemistry, National University of Singapore (NUS), Singapore 119007, Singapore., Luheshi NM; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, United Kingdom; MedImmune Ltd., Aaron Klug Building, Granta Park, Cambridge CB21 6GH, United Kingdom., Rivers-Auty J; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, United Kingdom., Green J; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, United Kingdom., Redondo-Castro E; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, United Kingdom., Kaldis P; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Department of Biochemistry, National University of Singapore (NUS), Singapore 119007, Singapore., Lopez-Castejon G; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom; Division of Infection, Immunity, and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Collaborative Centre of Inflammation Research, Manchester Academic Health Science Centre, Core Technology Facility, University of Manchester, Manchester M13 9PT, United Kingdom. Electronic address: Gloria.lopez-castejon@manchester.ac.uk., Brough D; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9PT, United Kingdom; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, United Kingdom. Electronic address: david.brough@manchester.ac.uk.

المصدر: The Journal of biological chemistry [J Biol Chem] 2019 May 24; Vol. 294 (21), pp. 8325-8335. Date of Electronic Publication: 2019 Apr 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Bone Marrow Cells/*metabolism , Interleukin-18/*metabolism , Interleukin-1alpha/*metabolism , Interleukin-1beta/*metabolism , Macrophages, Peritoneal/*metabolism, Animals ; Bone Marrow Cells/cytology ; Fibroblasts/cytology ; Fibroblasts/metabolism ; HeLa Cells ; Humans ; Hydrolyzable Tannins/pharmacology ; Macrophages, Peritoneal/cytology ; Mice ; Protein Transport/drug effects

المؤلفون: Rivers-Auty J; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK., Daniels MJD; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK., Colliver I; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK., Robertson DL; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, UK.; MRC University of Glasgow Centre for Virus Research, Sir Michael Stoker Building, 464 Bearsden Road, Glasgow, G61 1QH, Scotland, UK., Brough D; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK. david.brough@manchester.ac.uk.

المصدر: Nature communications [Nat Commun] 2018 Mar 20; Vol. 9 (1), pp. 1156. Date of Electronic Publication: 2018 Mar 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Evolution, Molecular*, Interleukin-1beta/*genetics, Animals ; Humans ; Interleukin-18/genetics ; Interleukin-18/metabolism ; Interleukin-1beta/metabolism ; Interleukin-33/genetics ; Interleukin-33/metabolism ; Multigene Family ; Phylogeny ; Receptors, Interleukin-1 Type I/genetics ; Receptors, Interleukin-1 Type I/metabolism ; Vertebrates/classification ; Vertebrates/genetics

المؤلفون: Daniels MJD; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK., Adamson AD; Transgenic unit, Faculty of Biology, Medicine and Health, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK., Humphreys N; Transgenic unit, Faculty of Biology, Medicine and Health, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK., Brough D; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK. david.brough@manchester.ac.uk.

المصدر: Scientific reports [Sci Rep] 2017 Dec 06; Vol. 7 (1), pp. 17077. Date of Electronic Publication: 2017 Dec 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems/*genetics , Cell Nucleus/*metabolism , Interleukin-1beta/*genetics, Animals ; Blood Platelets/cytology ; Blood Platelets/metabolism ; Bone Marrow Cells/cytology ; Bone Marrow Cells/drug effects ; Bone Marrow Cells/metabolism ; Cytokines/metabolism ; Gene Editing ; Ionomycin/pharmacology ; Lipopolysaccharides/pharmacology ; Macrophages/cytology ; Macrophages/immunology ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL ; Mutation ; Nigericin/pharmacology ; Nucleic Acid Conformation ; Phenotype ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Spleen/metabolism ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism

المؤلفون: Baldwin AG; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK., Rivers-Auty J; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK., Daniels MJD; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK., White CS; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK., Schwalbe CH; Aston Pharmacy School, School of Life & Health Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK., Schilling T; St. George's, University of London, Institute for Infection and Immunity, Cranmer Terrace, London SW17 0RE, UK., Hammadi H; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK., Jaiyong P; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK., Spencer NG; St. George's, University of London, Institute for Infection and Immunity, Cranmer Terrace, London SW17 0RE, UK., England H; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK., Luheshi NM; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK; MedImmune Ltd., Aaron Klug Building, Granta Park, Cambridge CB21 6GH, UK., Kadirvel M; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK., Lawrence CB; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK., Rothwell NJ; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK., Harte MK; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK., Bryce RA; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK., Allan SM; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK., Eder C; St. George's, University of London, Institute for Infection and Immunity, Cranmer Terrace, London SW17 0RE, UK., Freeman S; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK. Electronic address: sally.freeman@manchester.ac.uk., Brough D; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK. Electronic address: david.brough@manchester.ac.uk.

المصدر: Cell chemical biology [Cell Chem Biol] 2017 Nov 16; Vol. 24 (11), pp. 1321-1335.e5. Date of Electronic Publication: 2017 Sep 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Boron/*chemistry , Inflammasomes/*metabolism , NLR Family, Pyrin Domain-Containing 3 Protein/*antagonists & inhibitors, Animals ; Bone Marrow Cells/cytology ; Boron/pharmacology ; Boron Compounds/chemistry ; Boron Compounds/metabolism ; Boron Compounds/pharmacology ; Calcium/metabolism ; Cells, Cultured ; Crystallography, X-Ray ; Humans ; Inhibitory Concentration 50 ; Interleukin-1beta/metabolism ; Lipopolysaccharides/toxicity ; Macrophages/cytology ; Macrophages/drug effects ; Macrophages/metabolism ; Mice ; Molecular Conformation ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Structure-Activity Relationship