المؤلفون: Zhenwei Su, Jonathan Brooks, Jeffrey Pelker, Tatyana Andreyeva, Hanna Sobon, Roger Gifford, Matthew Powers, Jing Wang, Corey Dower, Martin Hegen, Dean Messing, Alfredo Darmanin Sheehan, Joseph J Brennan

المصدر: PLoS ONE, Vol 18, Iss 1, p e0280590 (2023)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/706fbbb9092845e5af906b0160784666

المؤلفون: Adam R. Root, Gurkan Guntas, Madan Katragadda, James R. Apgar, Jatin Narula, Chew Shun Chang, Sara Hanscom, Matthew McKenna, Jason Wade, Caryl Meade, Weijun Ma, Yongjing Guo, Yan Liu, Weili Duan, Claire Hendershot, Amy C. King, Yan Zhang, Eric Sousa, Amy Tam, Susan Benard, Han Yang, Kerry Kelleher, Fang Jin, Nicole Piche-Nicholas, Sinead E. Keating, Fernando Narciandi, Rosemary Lawrence-Henderson, Maya Arai, Wayne R. Stochaj, Kristine Svenson, Lidia Mosyak, Khetemcnee Lam, Christopher Francis, Kimberly Marquette, Liliana Wroblewska, H. Lily Zhu, Alfredo Darmanin Sheehan, Edward R. LaVallie, Aaron M. D’Antona, Alison Betts, Lindsay King, Edward Rosfjord, Orla Cunningham, Laura Lin, Puja Sapra, Lioudmila Tchistiakova, Divya Mathur, Laird Bloom

المصدر: mAbs, Vol 13, Iss 1 (2021)

مصطلحات موضوعية: T cell bispecific, T cell retargeting, T-BsAb, immuno-oncology, GUCY2C, Guanlyate cyclase 2c (GCC), Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/25a52ae4f12b462d933f760c7786789d

المؤلفون: Townsend, Sue, Fennell, Brian J., Apgar, James R., Lambert, Matthew, McDonnell, Barry, Grant, Joanne, Wade, Jason, Franklin, Edward, Foy, Niall, Shúilleabháin, Deirdre Ní, Fields, Conor, Darmanin-Sheehan, Alfredo, King, Amy, Paulsen, Janet E., Hickling, Timothy P., Tchistiakova, Lioudmila, Cunningham, Orla, Finlay, William J. J.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2015 Dec . 112(50), 15354-15359.

URL الوصول: https://www.jstor.org/stable/26466600

المؤلفون: Ronan O’Dwyer, Marina Kovaleva, Jiquan Zhang, John Steven, Emma Cummins, Deborah Luxenberg, Alfredo Darmanin-Sheehan, Miguel F. Carvalho, Matthew Whitters, Kenneth Saunders, Caroline J. Barelle

المصدر: Journal of Immunology Research, Vol 2018 (2018)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2314-8861; https://doaj.org/toc/2314-7156

URL الوصول: https://doaj.org/article/2040fb960ade4e4a81c4768f6494230b

المؤلفون: Orla Cunningham, Eric Sousa, Susan Benard, Yongjing Guo, C.M. Francis, Puja Sapra, Laura Lin, Lindsay King, Fang Jin, Weijun Ma, Aaron M. D’Antona, Nicole Piche-Nicholas, Sinead E. Keating, Sara Hanscom, Gurkan Guntas, Wayne Stochaj, Khetemcnee Lam, Claire Hendershot, Liliana Wroblewska, H. Lily Zhu, Kimberly Ann Marquette, Kristine Svenson, Divya Mathur, Fernando Narciandi, Yan Liu, Weili Duan, Edward R. Lavallie, Alison Betts, Rosemary Lawrence-Henderson, Chang Chew Shun, Adam Root, Maya Arai, Madan Katragadda, Amy King, Amy Tam, Jatin Narula, Jason Wade, Kerry Kelleher, Lioudmila Tchistiakova, Lidia Mosyak, Alfredo Darmanin Sheehan, Han Yang, Yan Zhang, James R. Apgar, Edward Rosfjord, Laird Bloom, Caryl L. Meade, Matthew McKenna

المصدر: mAbs
article-version (VoR) Version of Record

مصطلحات موضوعية: Bispecific antibody, CD3 Complex, T cell, CD3, T-Lymphocytes, Immunology, Receptors, Enterotoxin, Protein Engineering, Immunotherapy, Adoptive, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Report, Antibodies, Bispecific, developability, medicine, Immunology and Allergy, Animals, Humans, T-BsAb, T cell bispecific, immuno-oncology, Guanlyate cyclase 2c (GCC), 030304 developmental biology, 0303 health sciences, Mice, Inbred BALB C, Hybridomas, biology, antibody engineering, Chemistry, high-throughput protein production, PF-07062119, Macaca fascicularis, medicine.anatomical_structure, GUCY2C, 030220 oncology & carcinogenesis, Retargeting, biology.protein, Cancer research, antibody optimization, Female, T cell retargeting, Single-Chain Antibodies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c6dd5658cfd24d66b5b31b6d32bf8c
https://pubmed.ncbi.nlm.nih.gov/33459147

المؤلفون: Marina Kovaleva, Kenneth Saunders, Caroline J. Barelle, Matthew J. Whitters, Jiquan Zhang, Deborah Luxenberg, John Steven, Emma Cummins, Miguel F. Carvalho, Alfredo Darmanin-Sheehan, Ronan O’Dwyer

المصدر: Journal of Immunology Research, Vol 2018 (2018)
Journal of Immunology Research

مصطلحات موضوعية: 0301 basic medicine, lcsh:Immunologic diseases. Allergy, Article Subject, T-Lymphocytes, medicine.medical_treatment, T cell, Immunology, Receptors, Antigen, B-Cell, CHO Cells, Lymphocyte Activation, Major histocompatibility complex, medicine.disease_cause, Autoimmunity, Arthritis, Rheumatoid, Inducible T-Cell Co-Stimulator Protein, Inducible T-Cell Co-Stimulator Ligand, Mice, 03 medical and health sciences, Cricetulus, Antigen, Lymphocyte costimulation, medicine, Animals, Humans, Immunology and Allergy, Cell Proliferation, Inflammation, biology, Chemistry, CD28, General Medicine, Immunotherapy, Arthritis, Experimental, Disease Models, Animal, 030104 developmental biology, Cytokine, medicine.anatomical_structure, Mice, Inbred DBA, biology.protein, Cancer research, Female, Cell Surface Display Techniques, lcsh:RC581-607, Protein Binding, Single-Chain Antibodies, Research Article

وصف الملف: text/xhtml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b3534a19422f7eef7c47e6912dc79c
https://doaj.org/article/2040fb960ade4e4a81c4768f6494230b

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المؤلفون: Lioudmila Tchistiakova, Laird Bloom, Emma Cummins, Matthew Allister Lambert, William J.J. Finlay, Brian J. Fennell, Janet E. Paulsen, Deirdre Ní Shúilleabháin, Katarzyna Oficjalska, Orla Cunningham, Davinder Gill, Leeying Wu, Bénédicte Autin, Alfredo Darmanin-Sheehan

المصدر: The Journal of Immunology. 188:322-333

مصطلحات موضوعية: Mutation rate, Camelus, Immunology, Antibody Affinity, Biology, medicine.disease_cause, Germline, Mice, Species Specificity, medicine, Animals, Humans, Immunology and Allergy, Disulfides, Tyrosine, Genetics, chemistry.chemical_classification, Mutation, Protein Stability, Repertoire, Complementarity Determining Regions, Amino acid, Amino Acid Substitution, chemistry, biology.protein, Antibody, Immunoglobulin Heavy Chains, Chickens, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a61b59d65ec5b31889f044ee98369cc
https://doi.org/10.4049/jimmunol.1102466

المؤلفون: Orla Cunningham, Janet E. Paulsen, Barry McDonnell, Lioudmila Tchistiakova, Deirdre Ní Shúilleabháin, Joanne Grant, Sue Townsend, Alfredo Darmanin-Sheehan, Niall J. Foy, Conor Fields, Jason Wade, Brian J. Fennell, James R. Apgar, Amy King, Matthew Allister Lambert, William J.J. Finlay, Edward Franklin, Timothy P. Hickling

مصطلحات موضوعية: Models, Molecular, Molecular Sequence Data, Immunoglobulin Variable Region, Epitopes, T-Lymphocyte, Sequence alignment, Enzyme-Linked Immunosorbent Assay, tau Proteins, Complementarity determining region, Computational biology, Biology, Immunoglobulin G, Antibody Specificity, Peptide Library, Sequence Analysis, Protein, Animals, Humans, Computer Simulation, Amino Acid Sequence, Peptide library, Multidisciplinary, Protein Stability, Immunogenicity, Antibodies, Monoclonal, Biological Sciences, Complementarity Determining Regions, Clone Cells, Protein Structure, Tertiary, Rats, Germ Cells, Immunology, Mutation, biology.protein, Immunoglobulin heavy chain, Paratope, Immunoglobulin Light Chains, Antibody, Immunoglobulin Heavy Chains, Sequence Alignment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3ff8e127331263ac7e7116548eddc4
https://europepmc.org/articles/PMC4687607/

المؤلفون: Emma Cummins, Janet E. Paulsen, Orla Cunningham, Simon Evan Hufton, William J.J. Finlay, Nicole Piche, Debra D. Pittman, Alfredo Darmanin-Sheehan, Xiang Yang Tan, Lioudmila Tchistiakova, Matthew Allister Lambert, Xuemei Liu, Davinder Gill, Ciara M. Mahon, Cliona O'Sullivan, Jason M. Wade, Sreekumar Raman Kodangattil, Brian J. Fennell

المصدر: Journal of Molecular Biology. 388:541-558

مصطلحات موضوعية: Phage display, medicine.drug_class, DNA Mutational Analysis, Molecular Sequence Data, Receptor for Advanced Glycation End Products, Antibody Affinity, Complementarity determining region, Monoclonal antibody, Immunoglobulin G, Affinity maturation, Mice, Neutralization Tests, Structural Biology, medicine, Animals, Humans, Fluorometry, Amino Acid Sequence, Receptors, Immunologic, Molecular Biology, biology, Antibodies, Monoclonal, Complementarity Determining Regions, Molecular biology, Rats, Kinetics, Ribosome display, biology.protein, Paratope, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493450dd88e04c66d5839a43b6810c53
https://doi.org/10.1016/j.jmb.2009.03.019