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المؤلفون: Daniel P. Ball, Lydia P. Tsamouri, Alvin E. Wang, Hsin-Che Huang, Charles D. Warren, Qinghui Wang, Isabelle H. Edmondson, Andrew R. Griswold, Sahana D. Rao, Darren C. Johnson, Daniel A. Bachovchin
المصدر: Science immunology. 7(77)
مصطلحات موضوعية: Thioredoxins, Inflammasomes, Immunology, Humans, NLR Proteins, General Medicine, Adaptor Proteins, Signal Transducing
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97db046bb65efae70e49b89e898884a9
https://pubmed.ncbi.nlm.nih.gov/36332009 -
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المؤلفون: Darren C. Johnson, Kuo Gai, Marian C. Okondo, Sahana D. Rao, Ashley J. Chui, Daniel P. Ball, Daniel A. Bachovchin
المصدر: Cell Death and Disease, Vol 10, Iss 8, Pp 1-10 (2019)
Cell Death & Diseaseمصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Inflammasomes, Rats, Sprague-Dawley, Serine, Mice, 0302 clinical medicine, Mice, Inbred NOD, lcsh:Cytology, Immune cell death, Pyroptosis, Signal transducing adaptor protein, Inflammasome, Dipeptides, Transfection, Boronic Acids, Cell biology, Female, Toxoplasma, medicine.drug, Cell death, Proteases, Serine Proteinase Inhibitors, Bacterial Toxins, Immunology, Nerve Tissue Proteins, Biology, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, Cell death and immune response, medicine, Animals, Humans, Allele, lcsh:QH573-671, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Monocytes and macrophages, Alleles, Adaptor Proteins, Signal Transducing, Antigens, Bacterial, HEK 293 cells, Cell Biology, Rats, Rats, Zucker, Mice, Inbred C57BL, HEK293 Cells, RAW 264.7 Cells, 030104 developmental biology, Apoptosis Regulatory Proteins, 030217 neurology & neurosurgery
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المؤلفون: Daniel A. Bachovchin, Elizabeth L. Orth, Marian C. Okondo, Daniel P. Ball, Sahana D. Rao, Darren C. Johnson, Hsin-Che Huang
المصدر: Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 8, Pp 1-10 (2020)مصطلحات موضوعية: Cancer Research, Programmed cell death, Cell type, Proteases, Dipeptidases, Inflammasomes, Immunology, NLR Proteins, Lymphocyte Activation, Article, Cellular and Molecular Neuroscience, Mice, Cell death and immune response, medicine, Pyroptosis, Animals, Humans, Protease Inhibitors, Lymphocytes, lcsh:QH573-671, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Cells, Cultured, Adaptor Proteins, Signal Transducing, Innate immune system, lcsh:Cytology, Chemistry, Immune cell death, Cell Cycle, Inflammasome, Cell Biology, Cell biology, Neoplasm Proteins, Rats, CARD Signaling Adaptor Proteins, Apoptosis Regulatory Proteins, CD8, Intracellular, medicine.drug
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المؤلفون: Darren C. Johnson, Elizabeth L. Orth, Andrew R. Griswold, Cornelius Y. Taabazuing, Lauren E Vostal, Daniel A. Bachovchin, Ilana B. Kotliar, Daniel P. Ball, Sahana D. Rao
المصدر: Life Science Alliance
مصطلحات موضوعية: 0301 basic medicine, Inflammasomes, THP-1 Cells, animal diseases, Health, Toxicology and Mutagenesis, Caspase 1, Apoptosis, Plant Science, Biochemistry, Genetics and Molecular Biology (miscellaneous), 03 medical and health sciences, 0302 clinical medicine, Zymogen, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Pyroptosis, Humans, Research Articles, Adaptor Proteins, Signal Transducing, Ecology, Chemistry, NLRP1, HEK 293 cells, Signal transducing adaptor protein, Inflammasome, Cell biology, CARD Signaling Adaptor Proteins, 030104 developmental biology, HEK293 Cells, Signal transduction, Apoptosis Regulatory Proteins, Carrier Proteins, 030217 neurology & neurosurgery, medicine.drug, Research Article, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0856096b74dab554f03697a62c655627
http://europepmc.org/articles/PMC7025033 -
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المؤلفون: Ashraf Aboelela, Minoti V. Apte, Zhihong Xu, Longguang Jiang, Chen-Yi Cheung, Marie Ranson, Mingdong Huang, Karen Fildes, Michael J. Kelso, Gregory M. Cook, Daniel A. Bachovchin, Darren C. Johnson, Benjamin J. Buckley, Elahe Minaei, Simon M. Cook, Umar Ali
المصدر: Journal of Medicinal Chemistry. 61:8299-8320
مصطلحات موضوعية: Male, Models, Molecular, 0301 basic medicine, Lung Neoplasms, Protein Conformation, medicine.medical_treatment, Mice, Nude, Antineoplastic Agents, Mice, SCID, Pharmacology, Crystallography, X-Ray, Article, Metastasis, Amiloride, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Mice, Inbred NOD, Drug Discovery, Hydrolase, Tumor Cells, Cultured, medicine, Animals, Humans, Diuretics, Cell Proliferation, Mice, Inbred BALB C, Molecular Structure, integumentary system, Chemistry, Urokinase Plasminogen Activator, Sodium, Cancer, medicine.disease, Urokinase-Type Plasminogen Activator, Xenograft Model Antitumor Assays, Diuresis, Pancreatic Neoplasms, 030104 developmental biology, 030220 oncology & carcinogenesis, Potassium, Molecular Medicine, Female, Diuretic, medicine.drug
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المؤلفون: Cornelius Y. Taabazuing, Marian C. Okondo, Sahana D. Rao, Darren C. Johnson, Casie Reed, Elizabeth Peguero, Alex Kentsis, Elisa de Stanchina, Daniel A. Bachovchin, Ashley J. Chui, Fiona C. Brown
المصدر: Nature medicine
مصطلحات موضوعية: 0301 basic medicine, Myeloid, Cell, Biology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Cell Line, Tumor, hemic and lymphatic diseases, Pyroptosis, medicine, Humans, Protease Inhibitors, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Caspase 1, HEK 293 cells, Myeloid leukemia, Inflammasome, General Medicine, medicine.disease, 3. Good health, CARD Signaling Adaptor Proteins, Leukemia, Myeloid, Acute, Leukemia, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, Cell culture, Disease Progression, Cancer research, medicine.drug
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المؤلفون: Sarah E. Poplawski, David G. Sanford, Mitchell S. Wang, Eun Bin Go, Daniel A. Bachovchin, William W. Bachovchin, Yuxin Liu, Darren C. Johnson, Michael O Arciprete, Ramya Sridharan, Ashley J. Chui, Wengen Wu, Marian C. Okondo, Todd R. Golub, Jack H. Lai
المصدر: Nature Chemical Biology. 13:46-53
مصطلحات موضوعية: 0301 basic medicine, Dipeptidases, Proteases, Programmed cell death, Serine Proteinase Inhibitors, Molecular Conformation, Caspase 1, Article, Cell Line, Serine, Mice, Structure-Activity Relationship, 03 medical and health sciences, Pyroptosis, medicine, Animals, Humans, Macrophage, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Molecular Biology, Dose-Response Relationship, Drug, Chemistry, Macrophages, Monocyte, Dipeptides, Cell Biology, Boronic Acids, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Lytic cycle, Leukocytes, Mononuclear
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المؤلفون: Andrew R. Griswold, Elizabeth L. Orth, Ilana B. Kotliar, Sahana D. Rao, Cornelius Y. Taabazuing, Darren C. Johnson, Daniel P. Ball, Daniel A. Bachovchin
مصطلحات موضوعية: 0303 health sciences, Programmed cell death, NLRP1, Chemistry, animal diseases, Pyroptosis, Caspase 1, Inflammasome, Cell biology, 03 medical and health sciences, Cytosol, 0302 clinical medicine, Zymogen, medicine, Receptor, 030217 neurology & neurosurgery, 030304 developmental biology, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03aa86fd371012e628b49c3222dc2b21
https://doi.org/10.1101/681304 -
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المؤلفون: Karen Fildes, Darren C. Johnson, Chen-Yi Cheung, Elahe Minaei, Ashraf Aboelela, Michael J. Kelso, Mingdong Huang, Daniel A. Bachovchin, Hiwa Majed, Gregory M. Cook, Marie Ranson, Benjamin J. Buckley, Longguang Jiang
المصدر: Bioorg Med Chem Lett
مصطلحات موضوعية: Proteases, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, 01 natural sciences, Biochemistry, Article, Amiloride, Serine, Structure-Activity Relationship, Downregulation and upregulation, Drug Discovery, medicine, Humans, Neoplasm Metastasis, Diuretics, Molecular Biology, Serine protease, Urokinase, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Urokinase-Type Plasminogen Activator, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, biology.protein, Molecular Medicine, Diuretic, Plasminogen activator, medicine.drug
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المؤلفون: Andrew R. Griswold, Daniel P. Ball, Kuo Gai, Daniel A. Bachovchin, Brooke A. Vittimberga, Cornelius Y. Taabazuing, Marian C. Okondo, Elizabeth L. Orth, Ashley J. Chui, Darren C. Johnson, Sahana D. Rao
المصدر: Science (New York, N.Y.). 364(6435)
مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Proteasome Endopeptidase Complex, Serine Proteinase Inhibitors, Inflammasomes, THP-1 Cells, Proteolysis, Ubiquitin-Protein Ligases, Bacterial Toxins, Article, 03 medical and health sciences, Gene Knockout Techniques, Mice, 0302 clinical medicine, medicine, Pyroptosis, Animals, Humans, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Caspase, Antigens, Bacterial, Multidisciplinary, Innate immune system, medicine.diagnostic_test, biology, Chemistry, Intracellular parasite, HEK 293 cells, Caspase 1, Inflammasome, Immunity, Innate, Cell biology, 030104 developmental biology, HEK293 Cells, RAW 264.7 Cells, Host-Pathogen Interactions, biology.protein, CRISPR-Cas Systems, Apoptosis Regulatory Proteins, 030217 neurology & neurosurgery, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6c5a6eb47804aee583e545be9e34bc
https://pubmed.ncbi.nlm.nih.gov/31211982