المؤلفون: Elizabeth J. Beaudet, Ron Laethem, Steven J. Novick, Zhiyang Zhao, Thomas A. Brodie, Debie J. Hoivik, Andrews Robert Carl, Timothy K. Tippin, Edward L. LeCluyse, J. David Becherer, Jürgen M. Lehmann, Linda B. Moore, Darryl L. McDougald, Summer Jolley, Steven A. Kliewer, Michael D. Gaul, G. Hamilton, Kathy Mellon-Kusibab

المصدر: Drug Metabolism and Disposition. 31:870-877

مصطلحات موضوعية: Male, Receptors, Steroid, Matrix metalloproteinase inhibitor, Cell Culture Techniques, Drug Evaluation, Preclinical, Administration, Oral, Aminopyridines, Receptors, Cytoplasmic and Nuclear, Pharmaceutical Science, ADAM17 Protein, Matrix Metalloproteinase Inhibitors, chemistry.chemical_compound, In vivo, medicine, Animals, Cytochrome P-450 CYP3A, Humans, Rats, Wistar, Enzyme inducer, Pharmacology, chemistry.chemical_classification, Pregnane X receptor, Dose-Response Relationship, Drug, Formamides, biology, Pregnane, Pregnane X Receptor, Metalloendopeptidases, Oxidoreductases, N-Demethylating, Dipeptides, Amides, Molecular biology, Matrix Metalloproteinases, Rats, ADAM Proteins, Thiazoles, medicine.anatomical_structure, Enzyme, chemistry, Biochemistry, Enzyme inhibitor, Enzyme Induction, Hepatocyte, Hepatocytes, biology.protein, Drug Evaluation, Aryl Hydrocarbon Hydroxylases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728180f659f051cfc4b785f829bf565b
https://doi.org/10.1124/dmd.31.7.870

المؤلفون: Millard H, Lambert, R Kevin, Blackburn, Theresa D, Seaton, Daniel B, Kassel, Daniel S, Kinder, M Anthony, Leesnitzer, D Mark, Bickett, Janet R, Warner, Marc W, Andersen, Jennifer G, Badiang, David J, Cowan, Michael D, Gaul, Kimberly G, Petrov, Michael H, Rabinowitz, Robert W, Wiethe, J David, Becherer, Darryl L, McDougald, David L, Musso, Robert C, Andrews, Marcia L, Moss

المصدر: Combinatorial chemistryhigh throughput screening. 8(4)

مصطلحات موضوعية: Models, Molecular, Binding Sites, Protein Conformation, Tumor Necrosis Factor-alpha, Drug Evaluation, Preclinical, Biotin, Metalloendopeptidases, ADAM17 Protein, Mass Spectrometry, Recombinant Proteins, Substrate Specificity, ADAM Proteins, Structure-Activity Relationship, Peptide Library, Drug Design, Protein Interaction Mapping, Image Processing, Computer-Assisted, Protease Inhibitors, Peptides, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::993edb682148101da04f2a40507a6ade
https://pubmed.ncbi.nlm.nih.gov/16101009