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المؤلفون: Elizabeth J. Beaudet, Ron Laethem, Steven J. Novick, Zhiyang Zhao, Thomas A. Brodie, Debie J. Hoivik, Andrews Robert Carl, Timothy K. Tippin, Edward L. LeCluyse, J. David Becherer, Jürgen M. Lehmann, Linda B. Moore, Darryl L. McDougald, Summer Jolley, Steven A. Kliewer, Michael D. Gaul, G. Hamilton, Kathy Mellon-Kusibab
المصدر: Drug Metabolism and Disposition. 31:870-877
مصطلحات موضوعية: Male, Receptors, Steroid, Matrix metalloproteinase inhibitor, Cell Culture Techniques, Drug Evaluation, Preclinical, Administration, Oral, Aminopyridines, Receptors, Cytoplasmic and Nuclear, Pharmaceutical Science, ADAM17 Protein, Matrix Metalloproteinase Inhibitors, chemistry.chemical_compound, In vivo, medicine, Animals, Cytochrome P-450 CYP3A, Humans, Rats, Wistar, Enzyme inducer, Pharmacology, chemistry.chemical_classification, Pregnane X receptor, Dose-Response Relationship, Drug, Formamides, biology, Pregnane, Pregnane X Receptor, Metalloendopeptidases, Oxidoreductases, N-Demethylating, Dipeptides, Amides, Molecular biology, Matrix Metalloproteinases, Rats, ADAM Proteins, Thiazoles, medicine.anatomical_structure, Enzyme, chemistry, Biochemistry, Enzyme inhibitor, Enzyme Induction, Hepatocyte, Hepatocytes, biology.protein, Drug Evaluation, Aryl Hydrocarbon Hydroxylases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728180f659f051cfc4b785f829bf565b
https://doi.org/10.1124/dmd.31.7.870 -
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المؤلفون: Millard H, Lambert, R Kevin, Blackburn, Theresa D, Seaton, Daniel B, Kassel, Daniel S, Kinder, M Anthony, Leesnitzer, D Mark, Bickett, Janet R, Warner, Marc W, Andersen, Jennifer G, Badiang, David J, Cowan, Michael D, Gaul, Kimberly G, Petrov, Michael H, Rabinowitz, Robert W, Wiethe, J David, Becherer, Darryl L, McDougald, David L, Musso, Robert C, Andrews, Marcia L, Moss
المصدر: Combinatorial chemistryhigh throughput screening. 8(4)
مصطلحات موضوعية: Models, Molecular, Binding Sites, Protein Conformation, Tumor Necrosis Factor-alpha, Drug Evaluation, Preclinical, Biotin, Metalloendopeptidases, ADAM17 Protein, Mass Spectrometry, Recombinant Proteins, Substrate Specificity, ADAM Proteins, Structure-Activity Relationship, Peptide Library, Drug Design, Protein Interaction Mapping, Image Processing, Computer-Assisted, Protease Inhibitors, Peptides, Chromatography, Liquid
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::993edb682148101da04f2a40507a6ade
https://pubmed.ncbi.nlm.nih.gov/16101009