المؤلفون: Saskia Carstensen, Christina Gress, Veit J. Erpenbeck, Shamsah D. Kazani, Jens M. Hohlfeld, David A. Sandham, Meike Müller

المصدر: Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Eosinophil shape change, Type 2 innate lymphocyte cells, Asthma, PGD2, DP2, CRTH2, Diseases of the respiratory system, RC705-779

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1465-993X

URL الوصول: https://doaj.org/article/9ef12645bb7e4800853ed9a7b72fc9b0

المؤلفون: Christian Domingo, Oscar Palomares, David A. Sandham, Veit J. Erpenbeck, Pablo Altman

المصدر: Respiratory Research, Vol 19, Iss 1, Pp 1-8 (2018)

مصطلحات موضوعية: Asthma, Airway inflammation, Prostaglandin D2, Prostaglandin D2 receptor 2, Diseases of the respiratory system, RC705-779

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12931-018-0893-x; https://doaj.org/toc/1465-993X

URL الوصول: https://doaj.org/article/a5f93f7614e143f0b63e7d951a9d2a80

المؤلفون: Shamsah Kazani, Ian D. Pavord, Veit J. Erpenbeck, Yuan Ye, Jian Luo, Eric A. Shikatani, Rowie Borst, Wentao Chen, Paul Klenerman, Wei Liu, David Andrew Sandham, Ryan D. Hoyle, Luzheng Xue

المصدر: The Journal of Immunology. 206:2714-2724

مصطلحات موضوعية: integumentary system, Chemistry, medicine.medical_treatment, Immunology, Cell migration, Inflammation, Fevipiprant, Proinflammatory cytokine, Cell biology, 03 medical and health sciences, Paracrine signalling, 0302 clinical medicine, Cytokine, medicine, Immunology and Allergy, Cytotoxic T cell, lipids (amino acids, peptides, and proteins), medicine.symptom, Autocrine signalling, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4f4e6f0d56dcc8bb0c0fc560d48d8aea
https://doi.org/10.4049/jimmunol.2001245

المؤلفون: Giles Pergl-Wilson, Anna King, Julia Hatto, Henry Danahay, David Andrew Sandham, Mariana Oana Popa, Emily Stanley, Parmjit Bahra, Urs Baettig, Rebecca Butler, Brian Cox, Lightfoot Megan, Christopher J. Page, Alice Young, Paul J. Groot-Kormelink, Trixie Wagner, Swarupa Kulkarni, Glyn Hughes, Edward Charles Hall, David J. Rowlands, Lee Edwards, Atwood K. Cheung, Matthew Spendiff, Tom Sharp, Kamlesh Bala, Stephen Paul Collingwood, Hazel Watson, Julia Koehler, Oliver Ross Steward, Anne-Lise Glotin, Penny Wright, Cara E. Brocklehurst, Ulrike Glaenzel, Ian Nicholls, Richard I. Robinson, Roger J. Taylor, Catherine Howsham, Brian Everatt, Darren Le Grand, Hedaythul Choudhury, Gareth Williams, Emma Budd, Martin Gosling, Pamela Tranter

المصدر: Journal of Medicinal Chemistry. 64:7241-7260

مصطلحات موضوعية: Cystic Fibrosis, Drug Evaluation, Preclinical, Administration, Oral, Aminopyridines, Cystic Fibrosis Transmembrane Conductance Regulator, Pulmonary disease, 01 natural sciences, Cystic fibrosis, Rats, Sprague-Dawley, Pathogenesis, Pulmonary Disease, Chronic Obstructive, Structure-Activity Relationship, 03 medical and health sciences, Therapeutic approach, Drug Discovery, medicine, Animals, Humans, Clinical efficacy, 030304 developmental biology, 0303 health sciences, COPD, biology, Chemistry, Potentiator, medicine.disease, Cystic fibrosis transmembrane conductance regulator, Rats, respiratory tract diseases, 0104 chemical sciences, Disease Models, Animal, 010404 medicinal & biomolecular chemistry, Solubility, Immunology, biology.protein, Molecular Medicine, Gene Deletion, Half-Life, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795fc619db3aa5e70b7fe14aeddd53fe
https://doi.org/10.1021/acs.jmedchem.1c00343

المؤلفون: Jens M. Hohlfeld, Christina Gress, Saskia Carstensen, Shamsah Kazani, David Andrew Sandham, Veit J. Erpenbeck, Meike Müller

المصدر: Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Adult, Male, CRTH2, Adolescent, Prostaglandin Antagonists, Pyridines, medicine.medical_treatment, Receptors, Prostaglandin, Fevipiprant, Eosinophil shape change, Pharmacology, Diseases of the respiratory system, Young Adult, chemistry.chemical_compound, Type 2 innate lymphocyte cells, Cell Movement, 13,14-Dihydro-15-keto-PGD2, Eosinophil activation, medicine, PGD2 metabolites, Humans, PGD2, DP2, Lymphocytes, Receptors, Immunologic, Cell Shape, Cells, Cultured, Aged, Prostaglandin D2 receptor, Interleukin-13, RC705-779, Indoleacetic Acids, Prostaglandin D2, Research, Innate lymphoid cell, Middle Aged, Eosinophil, Asthma, Eosinophils, Cytokine, medicine.anatomical_structure, chemistry, lipids (amino acids, peptides, and proteins), Female, Cytokine secretion, Interleukin-5, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410ce53ce5849a40cfb9871315b76c80
https://doi.org/10.1186/s12931-021-01852-3

المؤلفون: Wentao, Chen, Jian, Luo, Yuan, Ye, Ryan, Hoyle, Wei, Liu, Rowie, Borst, Shamsah, Kazani, Eric A, Shikatani, Veit J, Erpenbeck, Ian D, Pavord, Paul, Klenerman, David A, Sandham, Luzheng, Xue

المصدر: The Journal of Immunology Author Choice

مصطلحات موضوعية: Inflammation, Indoleacetic Acids, Prostaglandin D2, Pyridines, Receptors, Prostaglandin, Humans, Mucosal Immunology, Receptors, Immunologic, Cells, Cultured, Coculture Techniques, T-Lymphocytes, Cytotoxic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::62200b4e46647048279944d747e4a3a3
https://pubmed.ncbi.nlm.nih.gov/34011519

المؤلفون: Vicky Verschut, Reinoud Gosens, Huib A. M. Kerstjens, Siti Farah Rahmawati, David Andrew Sandham, Manon Woest, Loes E. M. Kistemaker

المساهمون: Molecular Pharmacology, Groningen Research Institute for Asthma and COPD (GRIAC)

المصدر: European Respiratory Journal, 56(Suppl. 64). EUROPEAN RESPIRATORY SOC JOURNALS LTD

مصطلحات موضوعية: Goblet cell, Lung, biology, integumentary system, business.industry, Calponin, Inflammation, Airway remodeling, respiratory system, Asthma, Cell biology, respiratory tract diseases, Guinea pig, Ovalbumin, medicine.anatomical_structure, medicine, biology.protein, lipids (amino acids, peptides, and proteins), PGD2, medicine.symptom, Airway, business, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3161f5ac9a72493688d3bcbffbb18ac0
https://hdl.handle.net/11370/23a5b12c-78a6-41c5-83e8-7e34362af165

المؤلفون: Shamsah Kazani, Y. Ye, Luzheng Xue, David Andrew Sandham, Eric A. Shikatani, Wentao Chen

المصدر: D69. ASTHMA SUBPHENOTYPES, TARGETS AND THERAPEUTICS.

مصطلحات موضوعية: chemistry.chemical_compound, Tissue remodeling, Downregulation and upregulation, Chemistry, Prostaglandin, Fevipiprant, Autocrine signalling, Gene, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7cbddf396ddc754d8a5a1d5621d8e7b0
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7418

المؤلفون: Pablo Altman, David Andrew Sandham, Oscar Palomares, Veit J. Erpenbeck, Christian Domingo

المصدر: Respiratory Research, Vol 19, Iss 1, Pp 1-8 (2018)
Respiratory Research

مصطلحات موضوعية: 0301 basic medicine, Pathophysiology of asthma, Receptors, Prostaglandin, Prostaglandin, Review, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Immune system, Animals, Humans, Medicine, Anti-Asthmatic Agents, Receptors, Immunologic, Receptor, Lung, Inflammation, lcsh:RC705-779, business.industry, Prostaglandin D2, Innate lymphoid cell, Degranulation, lcsh:Diseases of the respiratory system, Asthma, respiratory tract diseases, 030104 developmental biology, 030228 respiratory system, chemistry, Prostaglandin D2 receptor 2, Immunology, Respiratory epithelium, Inflammation Mediators, business, Signal Transduction, Airway inflammation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4ba2547e365b6bae6ad754962734f9
http://link.springer.com/article/10.1186/s12931-018-0893-x

المؤلفون: Gerald Dubois, David Andrew Sandham, Francesca Levi-Schaffer, David Mankuta, Revital Shamri, Veit J. Erpenbeck

المصدر: Clinical & Experimental Allergy. 49:255-257

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Chemistry, Immunology, Fevipiprant, Receptor antagonist, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Eosinophil migration, Cancer research, medicine, Immunology and Allergy, Mast (botany), Receptor, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8a093dc879edeaa96e21601eccfe0c8d
https://doi.org/10.1111/cea.13304