نتائج البحث - "David A. Shivak"

1

دورية أكاديمية

Compact zinc finger architecture utilizing toxin-derived cytidine deaminases for highly efficient base editing in human cells

المؤلفون: Friedrich Fauser, Bhakti N. Kadam, Sebastian Arangundy-Franklin, Jessica E. Davis, Vishvesha Vaidya, Nicola J. Schmidt, Garrett Lew, Danny F. Xia, Rakshaa Mureli, Colman Ng, Yuanyue Zhou, Nicholas A. Scarlott, Jason Eshleman, Yuri R. Bendaña, David A. Shivak, Andreas Reik, Patrick Li, Gregory D. Davis, Jeffrey C. Miller

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/e253da149e064566bde5c2f0b036d5c3

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2

دورية أكاديمية

Diversifying the structure of zinc finger nucleases for high-precision genome editing

المؤلفون: David E. Paschon, Stephanie Lussier, Tenzin Wangzor, Danny F. Xia, Patrick W. Li, Sarah J. Hinkley, Nicholas A. Scarlott, Stephen C. Lam, Adam J. Waite, Lynn N. Truong, Nimisha Gandhi, Bhakti N. Kadam, Deepak P. Patil, David A. Shivak, Gary K. Lee, Michael C. Holmes, Lei Zhang, Jeffrey C. Miller, Edward J. Rebar

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/52399a6682884a7196ea64923e436811

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3

Enhancing gene editing specificity by attenuating DNA cleavage kinetics

المؤلفون: Andreas Reik, Sarah J. Hinkley, Nicholas A. Scarlott, Deepak P. Patil, Yuri R. Bendana, David A. Shivak, Tenzin Wangzor, Stephen Lam, Yuanyue Zhou, David Paschon, Lei Zhang, Patrick Li, Friedrich Fauser, Gary Lee, Jeffrey C. Miller, Charles B Paine, Danny F Xia, Edward J. Rebar, Hunter W. Richards

المصدر: Nature Biotechnology. 37:945-952

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8cc9ae3ffe9baf7fec7a19c03368407
https://doi.org/10.1038/s41587-019-0186-z

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4

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease

المؤلفون: Yasaman Ataei, Larry Park, D. James Surmeier, B. Joseph Vu, Seung Kwak, Richard T. Surosky, Anand Narayanan, David A. Shivak, Josee Laganiere, Christer Halldin, Andrea Varrone, Matthew C. Mendel, Karsten Tillack, Lei Zhang, Bryan Zeitler, Dmitry Guschin, Lexi Kopan, Sarah J. Hinkley, Kimberly Marlen, Jocelynn R. Pearl, Qi Yu, Taneli Heikkinen, Annette Gärtner, Yalda Sedaghat, Christina Thiede, Miklós Tóth, Jennifer M. Cherone, David Paschon, Jyothisri Kondapalli, Andrea E. Kudwa, Ladislav Mrzljak, Rainier Amora, Kimmo Lehtimäki, Edward J. Rebar, Lenke Tari, Ignacio Munoz-Sanjuan, Jeffrey C. Miller, Sylvie Ramboz, Marie Svedberg, Steven Froelich, Irina Ankoudinova, Philip D. Gregory, Stephen Lam, Michelle Day, Jonathan Bard, Hoang Oanh B. Nguyen, Fyodor D. Urnov, Davis Li, Jenny Haggkvist, H. Steve Zhang, Guijuan Qiao

المصدر: Nature Medicine. 25:1131-1142

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d19307c1ae395108f0cf1b74fb590fb6
https://doi.org/10.1038/s41591-019-0478-3

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5

Diversifying the structure of zinc finger nucleases for high-precision genome editing

المؤلفون: Deepak P. Patil, Stephanie Lussier, Bhakti N. Kadam, Edward J. Rebar, Gary K. Lee, Stephen Lam, Sarah J. Hinkley, Jeffrey C. Miller, Lei Zhang, Lynn N. Truong, Danny F Xia, Michael C. Holmes, Patrick Li, Adam James Waite, David Paschon, Nimisha Gandhi, Nicholas A. Scarlott, David A. Shivak, Tenzin Wangzor

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Base pair, Computer science, Science, General Physics and Astronomy, Locus (genetics), 02 engineering and technology, Computational biology, Protein Engineering, Cleavage (embryo), Genome, Article, General Biochemistry, Genetics and Molecular Biology, Viral Proteins, 03 medical and health sciences, Transformation, Genetic, INDEL Mutation, Genome editing, Peptide Library, Escherichia coli, Humans, Genomic library, Deoxyribonucleases, Type II Site-Specific, Peptide library, lcsh:Science, Base Pairing, Gene Editing, Genomic Library, Multidisciplinary, Base Sequence, Genome, Human, DNA-Directed RNA Polymerases, General Chemistry, 021001 nanoscience & nanotechnology, Zinc finger nuclease, Zinc Finger Nucleases, 030104 developmental biology, Genetic Loci, lcsh:Q, K562 Cells, 0210 nano-technology, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f5828a9ddac31055e987d36ff42281
http://link.springer.com/article/10.1038/s41467-019-08867-x

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6

Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primates

المؤلفون: Jenny Jiacheng Yan, Richard G. Trimble, Edward J. Rebar, Philip D. Gregory, Jianbin Wang, Christopher W. Peterson, Collette K. Tse, Krystin K. Norman, Hans-Peter Kiem, Michael C. Holmes, Olivier Humbert, David A. Shivak, Zachary K. Norgaard

المصدر: Blood. 127:2416-2426

مصطلحات موضوعية: 0301 basic medicine, Transplantation Conditioning, Receptors, CCR5, medicine.medical_treatment, Molecular Sequence Data, Immunology, Hematopoietic stem cell transplantation, Biology, Polymerase Chain Reaction, Transplantation, Autologous, Biochemistry, Cell Line, 03 medical and health sciences, Genome editing, medicine, Animals, Autologous transplantation, Cell Lineage, Amino Acid Sequence, RNA, Messenger, Progenitor cell, Bone Marrow Transplantation, Gene Editing, fungi, Graft Survival, Hematopoietic Stem Cell Transplantation, food and beverages, Zinc Fingers, Gene Therapy, Sequence Analysis, DNA, Cell Biology, Hematology, Hematopoietic Stem Cells, Transplantation, Haematopoiesis, Electroporation, 030104 developmental biology, Gene Knockdown Techniques, Mutation, Cancer research, Feasibility Studies, Macaca nemestrina, Stem cell, Whole-Body Irradiation, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf32dced56b5143fd48e469567eac1b9
https://doi.org/10.1182/blood-2015-09-672337

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In vivo genome editing of the albumin locus as a platform for protein replacement therapy

المؤلفون: Katherine A. High, Thomas Wechsler, Jeffrey C. Miller, Philip D. Gregory, Edward J. Rebar, Robert J. Davidson, Russell Dekelver, Julianne M. Rieders, Rajiv Sharma, David Paschon, Michael C. Holmes, Yannick Doyon, Scott Sproul, Xavier M. Anguela, David A. Shivak, Shangzhen Zhou

المصدر: Blood. 126:1777-1784

مصطلحات موضوعية: Mucopolysaccharidosis I, Transgene, Genetic Vectors, Immunology, Computational biology, Biology, Hemophilia A, Real-Time Polymerase Chain Reaction, Hemophilia B, Biochemistry, Genome, Factor IX, Mice, Protein replacement therapy, Genome editing, Albumins, Animals, Humans, Enzyme Replacement Therapy, RNA, Messenger, Transgenes, Promoter Regions, Genetic, Gene, Mucopolysaccharidosis II, Zinc finger, Genetics, Factor VIII, Gaucher Disease, Reverse Transcriptase Polymerase Chain Reaction, High-Throughput Nucleotide Sequencing, Zinc Fingers, Genetic Therapy, Gene Therapy, Cell Biology, Hematology, Dependovirus, Endonucleases, Zinc finger nuclease, Mice, Inbred C57BL, Liver, RNA editing, Fabry Disease, RNA Editing, Lysosomes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809efa3e52bee61f9b9c4e0bfc10f14c
https://doi.org/10.1182/blood-2014-12-615492

8

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease

المؤلفون: Bryan, Zeitler, Steven, Froelich, Kimberly, Marlen, David A, Shivak, Qi, Yu, Davis, Li, Jocelynn R, Pearl, Jeffrey C, Miller, Lei, Zhang, David E, Paschon, Sarah J, Hinkley, Irina, Ankoudinova, Stephen, Lam, Dmitry, Guschin, Lexi, Kopan, Jennifer M, Cherone, Hoang-Oanh B, Nguyen, Guijuan, Qiao, Yasaman, Ataei, Matthew C, Mendel, Rainier, Amora, Richard, Surosky, Josee, Laganiere, B Joseph, Vu, Anand, Narayanan, Yalda, Sedaghat, Karsten, Tillack, Christina, Thiede, Annette, Gärtner, Seung, Kwak, Jonathan, Bard, Ladislav, Mrzljak, Larry, Park, Taneli, Heikkinen, Kimmo K, Lehtimäki, Marie M, Svedberg, Jenny, Häggkvist, Lenke, Tari, Miklós, Tóth, Andrea, Varrone, Christer, Halldin, Andrea E, Kudwa, Sylvie, Ramboz, Michelle, Day, Jyothisri, Kondapalli, D James, Surmeier, Fyodor D, Urnov, Philip D, Gregory, Edward J, Rebar, Ignacio, Muñoz-Sanjuán, H Steve, Zhang

المصدر: Nature medicine. 25(7)

مصطلحات موضوعية: Male, Huntingtin Protein, Transcription, Genetic, Zinc Fingers, Neuroprotection, Mice, Inbred C57BL, Disease Models, Animal, Mice, Huntington Disease, Trinucleotide Repeats, Mutation, Mice, Inbred CBA, Animals, Humans, Female, Alleles, Cells, Cultured

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::4d3620bad8fe21aa64bd37ef53578561
https://pubmed.ncbi.nlm.nih.gov/31263285

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9

دورية أكاديمية

Translating dosage compensation to trisomy 21

المؤلفون: Jun Jiang, Yuanchun Jing, Gregory J. Cost, Jen-Chieh Chiang, Heather J. Kolpa, Allison M. Cotton, Dawn M. Carone, Benjamin R. Carone, David A. Shivak, Dmitry Y. Guschin, Jocelynn R. Pearl

المصدر: Nature, Nature. 500(7462):296-300

الإتاحة: https://ideas.repec.org/a/nat/nature/v500y2013i7462d10.1038_nature12394.html

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Targeted gene addition in human CD34(+) hematopoietic cells for correction of X-linked chronic granulomatous disease

المصدر: Nature biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa22394c835ea85f58c116d7cf78197
https://pubmed.ncbi.nlm.nih.gov/26950749

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