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المؤلفون: Adrienne A. Tymiak, Yingru Zhang, Jun Dai, David B. Wang-Iverson
المصدر: ADME-Enabling Technologies in Drug Design and Development
مصطلحات موضوعية: Chromatography, Chemistry, Supercritical fluid chromatography
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7b03d26e4fa7817c6e61ecacad8eaae5
https://doi.org/10.1002/9781118180778.ch24 -
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المؤلفون: William J. Pitts, Alaric J. Dyckman, Scott H. Watterson, Robert V. Moquin, Kim W. McIntyre, Zheng Yang, Jagabandhu Das, Katy Van Kirk, James R. Burke, David B. Wang-Iverson, Hollie Booth-Lute, James Kempson, Laishun Chen, Charles M. Langevine, Joel C. Barrish, Guchen Yang, Xiaoxia Yang, John H. Dodd, David S. Nirschl, Murray McKinnon, Steven H. Spergel, Mark A. Pattoli, Michael Galella, Kurt R. Gregor, Junquing Guo
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:7006-7012
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Biochemistry, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Acetamides, Drug Discovery, Animals, Humans, Inhibitory concentration 50, Structure–activity relationship, Potency, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Molecular Structure, Drug discovery, Organic Chemistry, Inflammatory Bowel Diseases, In vitro, I-kappa B Kinase, Rats, Enzyme Activation, chemistry, Molecular Medicine, Heterocyclic Compounds, 3-Ring, Acetamide, Tricyclic
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المؤلفون: Goodenough Angela, Shu-Pang Huang, Adrienne A. Tymiak, Wesley A. Turley, Shu Chang, Joelle M. Onorato, Zheng Ouyang, Sreeneeranj Kasichayanula, Richard C. Burrell, A. David Rodrigues, Mohammed Jemal, David B. Wang-Iverson, Marc Bifano, Frank LaCreta
المصدر: Chemical Research in Toxicology. 24:1575-1585
مصطلحات موضوعية: Adult, Male, Spectrometry, Mass, Electrospray Ionization, Time Factors, Chromatography, Resolution (mass spectrometry), Reproducibility of Results, General Medicine, Derivative, Toxicology, Tandem mass spectrometry, Mass spectrometry, Sensitivity and Specificity, Hydroxycholesterols, Standard curve, chemistry.chemical_compound, chemistry, Tandem Mass Spectrometry, Humans, Isobaric process, Sample preparation, Derivatization, Chromatography, High Pressure Liquid
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المؤلفون: Richard A. Hartz, Vivekananda M. Vrudhula, Richard A. Dalterio, David B. Wang-Iverson, Jingfang Qian-Cutrone, Joanne J. Bronson, Vijay T. Ahuja, Dauh-Rurng Wu
المصدر: Journal of Pharmaceutical and Biomedical Analysis. 54:602-606
مصطلحات موضوعية: animal structures, Resolution (mass spectrometry), Corticotropin-Releasing Hormone, Clinical Biochemistry, Phenylcarbamates, Substituent, Pharmaceutical Science, Receptors, Corticotropin-Releasing Hormone, Analytical Chemistry, chemistry.chemical_compound, Drug Discovery, Humans, Organic chemistry, Receptor, Spectroscopy, Alkyl, chemistry.chemical_classification, Ethanol, Chromatography, Supercritical Fluid, Stereoisomerism, Chiral resolution, chemistry, Pyrazines, Supercritical fluid chromatography, Amylose, Enantiomer
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المؤلفون: Bethanne M. Warrack, Hui Wei, Guodong Chen, Goodenough Angela, David B. Wang-Iverson, Adrienne A. Tymiak
المصدر: Drug Discovery Today. 16:58-64
مصطلحات موضوعية: Pharmacology, Chromatography, Protein therapeutics, Chemistry, Proteins, Computational biology, Mass spectrometry, Mass Spectrometry, Characterization (materials science), Biopharmaceutical industry, Protein structure, Pharmaceutical technology, Drug Discovery, Humans, Hydrogen–deuterium exchange, Forecasting
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المؤلفون: Charles M. Langevine, Joseph A. Furch, Dominique Belanger, Mark A. Pattoli, Joel C. Barrish, Alaric J. Dyckman, Marco Dodier, James Kempson, Jagabandhu Das, David S. Nirschl, Laishun Chen, Punit Marathe, Kathleen M. Gillooly, Junqing Guo, Robert V. Moquin, John H. Dodd, Murray McKinnon, Anne Marinier, Zheng Yang, Steven H. Spergel, Claude A. Quesnelle, Kim W. McIntyre, Katy Van Kirk, James R. Burke, William J. Pitts, Scott H. Watterson, Alain Martel, Patrice Gill, David B. Wang-Iverson, Tianle Li
المصدر: Journal of Medicinal Chemistry. 52:1994-2005
مصطلحات موضوعية: Lipopolysaccharides, Recombinant Fusion Proteins, IκB kinase, In Vitro Techniques, Crystallography, X-Ray, Chemical synthesis, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Animals, Humans, Thiazole, Oxazoles, Glutathione Transferase, Oxazole, chemistry.chemical_classification, Mice, Inbred BALB C, Tumor Necrosis Factor-alpha, Imidazoles, Biological activity, I-kappa B Kinase, Rats, Thiazoles, Enzyme, chemistry, Biochemistry, Leukocytes, Mononuclear, Microsomes, Liver, Molecular Medicine, Female, Signal transduction, Heterocyclic Compounds, 3-Ring, Tricyclic
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المؤلفون: Christian Caporuscio, Yingru Zhang, Jun Dai, Celia D’Arienzo, Anne Rose, Joseph B. Santella, David B. Wang-Iverson, Adrienne A. Tymiak, Michael Witkus
المصدر: Journal of Chromatography B. 875:154-160
مصطلحات موضوعية: Bioanalysis, Hydrocarbons, Fluorinated, Resolution (mass spectrometry), Metabolic Clearance Rate, Propanols, Metabolite, Clinical Biochemistry, Atmospheric-pressure chemical ionization, Biochemistry, High-performance liquid chromatography, Analytical Chemistry, Matrix (chemical analysis), chemistry.chemical_compound, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, Humans, Chromatography, High Pressure Liquid, Chromatography, Chemistry, Reproducibility of Results, Stereoisomerism, Cell Biology, General Medicine, Butanes, Microsomes, Liver, Stereoselectivity
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المؤلفون: Yingru Zhang, Jun Dai, Adrienne A. Tymiak, David B. Wang-Iverson
المصدر: Chirality. 19:683-692
مصطلحات موضوعية: Analytical chemistry, Helium, Catalysis, Analytical Chemistry, Diffusion, Countercurrent chromatography, Chromatography detector, Drug Discovery, Pressure, Chromatography, High Pressure Liquid, Spectroscopy, Pharmacology, Chromatography, Chemistry, Organic Chemistry, Temperature, Water, Chromatography, Supercritical Fluid, Stereoisomerism, Equipment Design, Carbon Dioxide, Displacement chromatography, Supercritical fluid, Chiral column chromatography, Radial chromatography, Models, Chemical, Two-dimensional chromatography, Supercritical fluid chromatography
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المؤلفون: Eric Swanson, Gary J. Grover, John D. Baxter, Hongjiang Zhang, Grazia Chiellini, Wolfgang H. Dillmann, Bernd Gloss, Thomas S. Scanlan, Tanya Volodarsky, Susanne U. Trost, David B. Wang-Iverson
المصدر: Endocrinology. 141:3057-3064
مصطلحات موضوعية: Agonist, medicine.medical_specialty, Messenger RNA, Thyroid hormone receptor, Cholesterol, medicine.drug_class, Endoplasmic reticulum, Biology, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, Myosin, Heart rate, medicine, Sobetirome
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1058a70651d2fc34e5018d6079fcc3f5
https://doi.org/10.1210/endo.141.9.7681 -
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المؤلفون: Aberra Fura, Guodong Chen, Adrienne A. Tymiak, David B. Wang-Iverson, Russell Weiner, Shujie J. Wang, Murli Krishna, Timothy V Olah, Karen Price, Paul E. Morin, Steven T. Wu, Jochem Gokemeijer, Mohammed Jemal
المصدر: Analytical and bioanalytical chemistry. 402(3)
مصطلحات موضوعية: Drug, Bioanalysis, medicine.drug_class, media_common.quotation_subject, Enzyme-Linked Immunosorbent Assay, Antigen-Antibody Complex, Monoclonal antibody, Biochemistry, Antibodies, Analytical Chemistry, Polyethylene Glycols, Pharmacokinetics, Western blot, Tandem Mass Spectrometry, medicine, Animals, media_common, Chromatography, biology, medicine.diagnostic_test, Chemistry, Proteins, Haplorhini, Epitope mapping, Pharmaceutical Preparations, biology.protein, Protein G, Antibody
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