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1دورية أكاديمية
المؤلفون: Eloy D. Hernandez, Lianxing Zheng, Young Kim, Bin Fang, Bo Liu, Reginald A. Valdez, William F. Dietrich, Paul V. Rucker, Donatella Chianelli, James Schmeits, Dingjiu Bao, Jocelyn Zoll, Claire Dubois, Glenn C. Federe, Lihao Chen, Sean B. Joseph, Lloyd B. Klickstein, John Walker, Valentina Molteni, Peter McNamara, Shelly Meeusen, David C. Tully, Michael K. Badman, Jie Xu, Bryan Laffitte
المصدر: Hepatology Communications, Vol 3, Iss 8, Pp 1085-1097 (2019)
مصطلحات موضوعية: Diseases of the digestive system. Gastroenterology, RC799-869
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2471-254X
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المؤلفون: Sean B. Joseph, Paul Vincent Rucker, Peter McNamara, Michael Badman, Todd Groessl, Chianelli Donatella, Bo Liu, Alan Chu, Yugang Liu, Badry Bursulaya, H. Martin Seidel, Young Kim, John Nelson, Valentina Molteni, David C. Tully, David J Huang, Wendy Richmond, Andrew Phimister, Dingjiu Bao, Jane Wu, Thierry Schlama, Jason Roland, Eloy D. Hernandez, Bryan Laffitte, Jocelyn Zoll, Mahavir Prashad, Ignacio Sancho-Martinez, Robert Hill, Xiaodong Liu, James Schmeits
المصدر: Journal of medicinal chemistry. 63(8)
مصطلحات موضوعية: Therapeutic gene modulation, Agonist, Male, medicine.drug_class, Receptors, Cytoplasmic and Nuclear, Pharmacology, Chenodeoxycholic Acid, Diet, High-Fat, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Mice, Dogs, In vivo, Fibrosis, Non-alcoholic Fatty Liver Disease, Chenodeoxycholic acid, Drug Discovery, medicine, Animals, Humans, Benzothiazoles, Receptor, 030304 developmental biology, 0303 health sciences, Chemistry, Obeticholic acid, Isoxazoles, medicine.disease, 0104 chemical sciences, Protein Structure, Tertiary, Rats, Mice, Inbred C57BL, 010404 medicinal & biomolecular chemistry, Treatment Outcome, Molecular Medicine, Farnesoid X receptor
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المؤلفون: Peter McNamara, Jocelyn Zoll, Lianxing Zheng, Shelly Meeusen, Young Kim, Glenn C. Federe, Lihao Chen, Eloy D. Hernandez, John R. Walker, Dingjiu Bao, Lloyd B. Klickstein, William F. Dietrich, Paul Vincent Rucker, Valentina Molteni, Bin Fang, Reginald Valdez, Sean B. Joseph, Bo Liu, James Schmeits, Claire Dubois, Chianelli Donatella, Michael Badman, David C. Tully, Bryan Laffitte, Jie Xu
المصدر: Hepatology Communications
Hepatology Communications, Vol 3, Iss 8, Pp 1085-1097 (2019)مصطلحات موضوعية: Agonist, Hepatology, medicine.drug_class, business.industry, Amylin, Obeticholic acid, Original Articles, Pharmacology, medicine.disease, digestive system, digestive system diseases, Transcriptome, chemistry.chemical_compound, chemistry, Fibrosis, Nonalcoholic fatty liver disease, medicine, lcsh:Diseases of the digestive system. Gastroenterology, Farnesoid X receptor, Original Article, lcsh:RC799-869, Steatohepatitis, business
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المؤلفون: Xiaolei Ma, Gladys T. Muiru, Vincent H. J. Leonard, Yongjin Xu, Dirksen E. Bussiere, Weidong Zhong, Charles Wartchow, David C. Tully, Warne Robert L, Steven Shia, Kyoko Uehara, Alexey Rivkin, Isabel Zaror, Lili Xie, Dianna M. Baldwin
المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reportsمصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Science, viruses, Protein subunit, Molecular Conformation, Biology, medicine.disease_cause, Antiviral Agents, Article, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Transcription (biology), RNA polymerase, Heterotrimeric G protein, Influenza A virus, medicine, Viral structural protein, Humans, Binding site, Polymerase, Binding Sites, Multidisciplinary, Molecular Structure, virus diseases, biochemical phenomena, metabolism, and nutrition, RNA-Dependent RNA Polymerase, Molecular biology, Cell biology, Protein Subunits, 030104 developmental biology, chemistry, biology.protein, Medicine, Protein Binding
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المؤلفون: Chek Shik Lim, Advait Nagle, Chun Li, Clemens H. M. Kocken, Pranab Mishra, Tove Tuntland, Wei Lin Sandra Sim, Rachel Borboa, Case W. McNamara, Seh Yong Leong, Nobutaka Kato, Christophe Bodenreider, Anne-Marie Zeeman, Prasuna Guntapalli, Kelli Kuhen, Thomas Hollenbeck, Thierry T. Diagana, Arnab K. Chatterjee, Elizabeth A. Winzeler, Liying Jocelyn Tan, Jonathan Chang, Siti Nurdiana Abas, Paul W. Smith, Bryan K. S. Yeung, Yong Cheng Tan, David C. Tully, Jason Roland, Suresh B. Lakshminarayana, Bin Zou, Kerstin Gagaring
المصدر: ACS Medicinal Chemistry Letters. 5:947-950
مصطلحات موضوعية: 0303 health sciences, Imidazopyridine, 030306 microbiology, Phenotypic screening, Organic Chemistry, Cell, Biology, Simian, Bioinformatics, biology.organism_classification, Biochemistry, Virology, Plasmodium, 3. Good health, 03 medical and health sciences, medicine.anatomical_structure, In vivo, parasitic diseases, Drug Discovery, medicine, Structure–activity relationship, Parasite hosting, 030304 developmental biology
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المؤلفون: Xuena Lin, Kelli Kuhen, Tao Wu, Elizabeth A. Winzeler, Christoph Fischli, Chun Li, Kerstin Gagaring, Jared Ek, Tiffany Chuan, Suresh B. Lakshminarayana, Rachel Borboa, Thomas Hollenbeck, Arnab K. Chatterjee, Fenghua Liu, Thierry T. Diagana, Richard Glynne, Caroline Francek, Reto Brun, Advait Nagle, John Isbell, Bo Liu, Christopher Caldwell, David C. Tully, David Plouffe, Tove Tuntland, Philip B. Alper, Suzanne Skolnik, Jonathan Chang, Jianling Wang, Matthias Rottmann, Zhong Chen
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Plasmodium falciparum, Biological Availability, Pharmacology, Article, Piperazines, Antimalarials, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Pharmacokinetics, In vivo, Drug Discovery, Animals, Humans, Structure–activity relationship, Potency, Antimalarial Agent, Malaria, Falciparum, Rats, Wistar, Mice, Inbred BALB C, biology, Imidazoles, biology.organism_classification, In vitro, Rats, Piperazine, chemistry, Molecular Medicine, Caco-2 Cells
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المؤلفون: Jennifer L. Harris, David C. Tully, Michael Hornsby, Badry Bursulaya, Henry Danahay, Glen Spraggon, Aaron Shipway, Scott A. Lesley
المصدر: Protein Science. 18:1081-1094
مصطلحات موضوعية: Camostat, Proteases, Gabexate, Cations, Divalent, Protein Conformation, Stereochemistry, medicine.medical_treatment, Crystallography, X-Ray, Guanidines, Biochemistry, Article, Substrate Specificity, Divalent, chemistry.chemical_compound, Aprotinin, Protein structure, Catalytic Domain, medicine, Chymotrypsin, Humans, Protease Inhibitors, Molecular Biology, chemistry.chemical_classification, Serine protease, Protease, biology, Serine Endopeptidases, Active site, Esters, Sodium ion transport, chemistry, biology.protein, Calcium, Sequence Alignment
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8
المؤلفون: Henry Danahay, Michael J. Roberts, Badry Bursulaya, H. Michael Petrassi, Vidal Agnes, Arnab K. Chatterjee, Jennifer A. Williams, Andrew M. Schumacher, David C. Tully, Aaron Shipway, Reynand Pacoma, Glen Spraggon, Jennifer L. Harris
المصدر: Bioorganic & Medicinal Chemistry Letters. 18:5895-5899
مصطلحات موضوعية: Serine Proteinase Inhibitors, Molecular model, Protein Conformation, Peptidomimetic, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Structure-Activity Relationship, Drug Discovery, medicine, Combinatorial Chemistry Techniques, Molecular Biology, chemistry.chemical_classification, Protease, Molecular Structure, biology, Molecular Mimicry, Serine Endopeptidases, Organic Chemistry, PRSS8, Active site, Small molecule, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine
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المؤلفون: Ingo H. Engels, Jie Xu, Andrew M. Schumacher, Mauricio Montal, Ardem Patapoutian, David C. Tully, Michael Bandell, Bertrand Coste, H. Michael Petrassi, Truc Huynh, Adrienne E. Dubin, Jianmin Lao, Jayanti Mathur, Jason T. Matzen, Ruhma Syeda
مصطلحات موضوعية: Chemistry, PIEZO1, Biophysics, Channel (broadcasting), Mechanotransduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ccc77fd24b055190a28d6739a4e590f2
https://doi.org/10.7554/elife.07369.008 -
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المؤلفون: Jianmin Lao, Michael Bandell, H. Michael Petrassi, David C. Tully, Truc Huynh, Adrienne E. Dubin, Jie Xu, Jason T. Matzen, Jayanti Mathur, Mauricio Montal, Ruhma Syeda, Bertrand Coste, Andrew M. Schumacher, Ardem Patapoutian, Ingo H. Engels
المساهمون: Laboratoire de Neurosciences Cognitives [Marseille] (LNC), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)
المصدر: eLife, Vol 4 (2015)
eLife
eLife, eLife Sciences Publication, 2015, 4, ⟨10.7554/eLife.07369⟩
eLife, 2015, 4, ⟨10.7554/eLife.07369⟩مصطلحات موضوعية: QH301-705.5, [SDV]Life Sciences [q-bio], Science, General Biochemistry, Genetics and Molecular Biology, Cell membrane, medicine, Mechanotransduction, Biology (General), agonist, Ion channel, mechanotransduction, General Immunology and Microbiology, Artificial cell, Chemistry, General Neuroscience, PIEZO1, Small Molecule Libraries, General Medicine, Anatomy, medicine.anatomical_structure, Membrane, Structural biology, ion channel, Biophysics, Medicine