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1
المؤلفون: Yasheen Zhou, Yongping Xie, Aye Aye Mar, Michael T. Flavin, Ali Koohang, David E. Zembower, Matthew M. Ames, Ze Qi Xu, Mary J. Kuffel, Rama K. Mishra
المساهمون: Zembower, David E, Xie, Yongping, Koohang, Ali, Kuffel, Mary J, Ames, Matthew M, Zhou, Yasheen, Mishra, Rama Kumar Umar, Mar, Aye Aye, Flavin, Michael T, Xu, Zeqi
المصدر: Anti-Cancer Agents in Medicinal Chemistry. 12:1117-1131
مصطلحات موضوعية: Cancer Research, Indoles, Stereochemistry, Carbazoles, Antineoplastic Agents, Topoisomerase-I Inhibitor, Biology, Methylenedioxy, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Neoplasms, Humans, antitumor activity, Ethylenedioxy, Cell Proliferation, Pharmacology, Indole test, Topoisomerase, methylenedioxy, In vitro, inhibitor, DNA Topoisomerases, Type I, Biochemistry, chemistry, biology.protein, Molecular Medicine, DNA supercoil, Drug Screening Assays, Antitumor, Topoisomerase I Inhibitors, DNA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04c9b7880d733ae40352813b8cd28e5
https://doi.org/10.2174/187152012803529628 -
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المؤلفون: Margret Thorsteinnsdottir, Alex S. Kiselyov, Gudmundur Sigthorsson, Rama K. Mishra, Jose Ramirez, Peng Yu, Nian Zhou, Jun Zhang, Emmanuel Onua, Mark E. Gurney, Georgeta Hategan, Thorkell Andresson, David E. Zembower, Wayne Zeller, Jasbir Singh, Alex Polozov
المصدر: Journal of Medicinal Chemistry. 53:18-36
مصطلحات موضوعية: Sulfonyl, chemistry.chemical_classification, Stereochemistry, Antagonist, Prostanoid, Chemical synthesis, Adenosine diphosphate, chemistry.chemical_compound, chemistry, Drug Discovery, medicine, Molecular Medicine, Structure–activity relationship, lipids (amino acids, peptides, and proteins), Prostaglandin E2, Pharmacophore, medicine.drug
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المؤلفون: Gudrun Halldorsdottir, Gudmundur Sigthorsson, Heida Sigthorsdottir, Thorkell Andresson, Jennifer Winger, Emmanuel Onua, Livia A. Enache, Margret Thorsteinnsdottir, Bjorn Mamat, Douglas R. Davies, Jun Zhang, Monica Keyvan, David Sullins, Alex S. Kiselyov, Rama K. Mishra, Audur Thorlaksdottir, Li-Ming Zhou, David E. Zembower, Michael Krohn, Vincent Sandanayaka, Lance Stewart, Mark E. Gurney, Jasbir Singh
المصدر: Journal of Medicinal Chemistry. 53:573-585
مصطلحات موضوعية: Leukotriene B4, Stereochemistry, Myocardial Infarction, Biological Availability, Context (language use), Crystallography, X-Ray, Ligands, Chemical synthesis, Leukotriene-A4 hydrolase, Structure-Activity Relationship, chemistry.chemical_compound, Heterocyclic Compounds, Drug Discovery, Hydrolase, Humans, Enzyme Inhibitors, Epoxide Hydrolases, Leukotriene, Ligand efficiency, Drug discovery, Peptide Fragments, Stroke, Butyrates, Solubility, chemistry, Biochemistry, Cardiovascular Diseases, Molecular Medicine
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4
المؤلفون: Sergey Dzekhtser, Michael Krohn, Isaac Kennedy, Changren Yan, David E. Zembower, Glenn L. Stahl, Chen Wei, Robert A. Erickson, Livia A. Enache, Dragan Ristic, Alex S. Kiselyov, Frank W. Muellner, Vincent Sandanayaka, Jennifer Winger, David Sullins, Jasbir Singh
المصدر: Organic Process Research & Development. 13:1177-1184
مصطلحات موضوعية: Chemistry, Organic Chemistry, Final product, Combinatorial chemistry, Small molecule, Coupling reaction, law.invention, Leukotriene-A4 hydrolase, Nucleophile, law, Electrophile, Organic chemistry, Process optimization, Physical and Theoretical Chemistry, Crystallization
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5
المؤلفون: Alex B. Burgin, Magnus H. Haraldsson, Brian Pease, Hidong Kim, Douglas R. Davies, Lance Stewart, David E. Zembower, Rama K. Mishra, Alex S. Kiselyov, Jasbir Singh, Jeff Christensen, Mark E. Gurney, Olafur T. Magnusson, Bjorn Mamat, Erik C Hansen
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Stereochemistry, Allosteric regulation, Crystallography, X-Ray, 010402 general chemistry, 01 natural sciences, Article, Leukotriene-A4 hydrolase, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, Hydrolase, Humans, Metabolomics, Structure–activity relationship, Enzyme Inhibitors, Binding site, 030304 developmental biology, Epoxide Hydrolases, Indole test, 0303 health sciences, Binding Sites, Drug discovery, Chemistry, Hydrogen Bonding, Small molecule, 0104 chemical sciences, 3. Good health, Crystallography, Biochemistry, Molecular Medicine
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6Peptide boronic acids Versatile synthetic ligands for affinity chromatography of serine proteinases*
المؤلفون: David E. Zembower, Cheryl L. Neudauer, Myra J. Wick, Matthew M. Ames
المصدر: International Journal of Peptide and Protein Research. 47:405-413
مصطلحات موضوعية: chemistry.chemical_classification, Serine Proteinase Inhibitors, Elastase, Peptide, Cathepsin G, Ligands, Boronic Acids, Biochemistry, Chromatography, Affinity, Sepharose, chemistry.chemical_compound, Enzyme, chemistry, Affinity chromatography, Animals, Humans, Cattle, Pancreatic elastase, Boronic acid
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7176c289b6ab078b1819d6f72cefdcb
https://doi.org/10.1111/j.1399-3011.1996.tb01090.x -
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المؤلفون: Matthew O'Connell, Livia A. Enache, Siead I. Zegar, David E. Zembower, Christopher J. Tokar, Wayne Zeller, Venkat Rajagopol, Frank W. Muellner, Jasbir Singh
المصدر: Organic Process Research & Development. 11:747-753
مصطلحات موضوعية: Indole test, Ep3 receptor, Tandem, Chemistry, Stereochemistry, Heck reaction, Intramolecular force, Organic Chemistry, Antagonist, Sequence (biology), Physical and Theoretical Chemistry, Small molecule
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المؤلفون: Nancy Jimenez, David E. Zembower, Michael T. Flavin, Eric W. Kirchhoff, Prabir Sen, and Ze-Qi Xu, Jintao Zhang
المصدر: Organic Process Research & Development. 4:577-580
مصطلحات موضوعية: Anti hiv, business.industry, Computer science, Process research, Organic Chemistry, Total synthesis, Calanolide A, Combinatorial chemistry, Scientific method, Yield (chemistry), Key (cryptography), Physical and Theoretical Chemistry, Process engineering, business, Friedel–Crafts reaction
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المؤلفون: David E. Zembower, Heping Zhang
المصدر: The Journal of Organic Chemistry. 63:9300-9305
مصطلحات موضوعية: Stereochemistry, Organic Chemistry, Regioselectivity, Halogenation, Total synthesis, Robustaflavone, Hepatitis B, medicine.disease, In vitro, chemistry.chemical_compound, chemistry, Apigenin, medicine, Derivative (chemistry)
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المؤلفون: John D. Rizzo, Tracy L. Stup, Michael T. Flavin, Albert Khilevich, Robert W. Buckheit, Lin Lin, David E. Zembower, Ze-Qi Xu
المصدر: Bioorganic & Medicinal Chemistry Letters. 8:2179-2184
مصطلحات موضوعية: Anti-HIV Agents, viruses, Clinical Biochemistry, Pharmaceutical Science, In Vitro Techniques, Virus Replication, medicine.disease_cause, Pyranocoumarins, Biochemistry, Monocytes, Virus, Cell Line, Structure-Activity Relationship, Coumarins, Drug Discovery, Leukocytes, medicine, Humans, Molecular Biology, chemistry.chemical_classification, Acquired Immunodeficiency Syndrome, biology, Macrophages, Organic Chemistry, virus diseases, Biological activity, Simian immunodeficiency virus, biology.organism_classification, Virology, HIV Reverse Transcriptase, Reverse transcriptase, In vitro, Enzyme, chemistry, Chromones, Enzyme inhibitor, Drug Design, Lentivirus, HIV-1, biology.protein, Reverse Transcriptase Inhibitors, Molecular Medicine, Simian Immunodeficiency Virus