-
1دورية أكاديمية
المؤلفون: Oliver Brylski, Puja Shrestha, Patricia Gnutt, David Gnutt, Jonathan Wolf Mueller, Simon Ebbinghaus
المصدر: Frontiers in Molecular Biosciences, Vol 8 (2021)
مصطلحات موضوعية: PAPS synthase, ATP depletion, in-cell spectroscopy, protein folding stability, alanine scanning, ligand binding, Biology (General), QH301-705.5
وصف الملف: electronic resource
-
2دورية أكاديمية
المؤلفون: David Gnutt, Linda Sistemich, Simon Ebbinghaus
المصدر: Frontiers in Molecular Biosciences, Vol 6 (2019)
مصطلحات موضوعية: cytomimetic media, protein folding and stability, in-cell spectroscopy, Macromolecular crowding, fast relaxation imaging (FReI), Biology (General), QH301-705.5
وصف الملف: electronic resource
-
3
المؤلفون: Srinivas Niranj Chandrasekaran, Jeanelle Ackerman, Eric Alix, D. Michael Ando, John Arevalo, Melissa Bennion, Nicolas Boisseau, Adriana Borowa, Justin D. Boyd, Laurent Brino, Patrick J. Byrne, Hugo Ceulemans, Carolyn Ch’ng, Beth A. Cimini, Djork-Arne Clevert, Nicole Deflaux, John G Doench, Thierry Dorval, Regis Doyonnas, Vincenza Dragone, Ola Engkvist, Patrick W. Faloon, Briana Fritchman, Florian Fuchs, Sakshi Garg, Tamara J. Gilbert, David Glazer, David Gnutt, Amy Goodale, Jeremy Grignard, Judith Guenther, Yu Han, Zahra Hanifehlou, Santosh Hariharan, Desiree Hernandez, Shane R Horman, Gisela Hormel, Michael Huntley, Ilknur Icke, Makiyo Iida, Christina B. Jacob, Steffen Jaensch, Jawahar Khetan, Maria Kost-Alimova, Tomasz Krawiec, Daniel Kuhn, Charles-Hugues Lardeau, Amanda Lembke, Francis Lin, Kevin D. Little, Kenneth R. Lofstrom, Sofia Lotfi, David J. Logan, Yi Luo, Franck Madoux, Paula A. Marin Zapata, Brittany A. Marion, Glynn Martin, Nicola Jane McCarthy, Lewis Mervin, Lisa Miller, Haseeb Mohamed, Tiziana Monteverde, Elizabeth Mouchet, Barbara Nicke, Arnaud Ogier, Anne-Laure Ong, Marc Osterland, Magdalena Otrocka, Pieter J. Peeters, James Pilling, Stefan Prechtl, Chen Qian, Krzysztof Rataj, David E Root, Sylvie K. Sakata, Simon Scrace, Hajime Shimizu, David Simon, Peter Sommer, Craig Spruiell, Iffat Sumia, Susanne E Swalley, Hiroki Terauchi, Amandine Thibaudeau, Amy Unruh, Jelle Van de Waeter, Michiel Van Dyck, Carlo van Staden, Michał Warchoł, Erin Weisbart, Amélie Weiss, Nicolas Wiest-Daessle, Guy Williams, Shan Yu, Bolek Zapiec, Marek Żyła, Shantanu Singh, Anne E. Carpenter
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0ad294298f87b0d35776a491fba28d7f
https://doi.org/10.1101/2023.03.23.534023 -
4
المؤلفون: Nirnay Samanta, Yasser B. Ruiz‐Blanco, Zamira Fetahaj, David Gnutt, Carter Lantz, Joseph A. Loo, Elsa Sanchez‐Garcia, Simon Ebbinghaus
المصدر: Chembiochem : a European journal of chemical biology, vol 23, iss 21
مصطلحات موضوعية: amyotrophic lateral sclerosis, Protein Folding, Bioengineering, Neurodegenerative, Biochemistry, Medicinal and Biomolecular Chemistry, Rare Diseases, Superoxide Dismutase-1, medicinal chemistry, supramolecular ligands, Nanotechnology, 2.1 Biological and endogenous factors, Humans, Aetiology, Molecular Biology, CLR01, Superoxide Dismutase, Organic Chemistry, Amyotrophic Lateral Sclerosis, Neurosciences, Neurodegenerative Diseases, SOD1, Brain Disorders, 5.1 Pharmaceuticals, Neurological, Mutation, Molecular Medicine, Biochemistry and Cell Biology, ALS, Development of treatments and therapeutic interventions, Biologie
وصف الملف: application/pdf
-
5
المؤلفون: Simon Ebbinghaus, Stepan Timr, Fabio Sterpone, David Gnutt
المساهمون: Laboratoire de biochimie théorique [Paris] (LBT (UPR_9080)), Institut de biologie physico-chimique (IBPC (FR_550)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Ruhr-Universität Bochum [Bochum], Technische Universität Braunschweig = Technical University of Braunschweig [Braunschweig], This project has received funding from the European Union's Horizon 2020 research andinnovation programme under the Marie Sklodowska-Curie grant agreement No 840395., European Project: 840395,CROWDY, Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)
المصدر: Journal of Physical Chemistry Letters
Journal of Physical Chemistry Letters, 2020, ⟨10.1021/acs.jpclett.0c00699⟩
Journal of Physical Chemistry Letters, American Chemical Society, 2020, ⟨10.1021/acs.jpclett.0c00699⟩
The Journal of Physical Chemistry Lettersمصطلحات موضوعية: macromolecular crowding, Light, Molecular Dynamics Simulation, 010402 general chemistry, 01 natural sciences, thermal stability, Superoxide dismutase, 03 medical and health sciences, Molecular dynamics, Superoxide Dismutase-1, superoxide dismutase 1, Animals, General Materials Science, Physical and Theoretical Chemistry, Bovine serum albumin, 030304 developmental biology, Protein Unfolding, 0303 health sciences, biology, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Chemistry, Serum Albumin, Bovine, mutations, 0104 chemical sciences, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, [SDV.BBM.BP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biophysics, Excluded volume, biology.protein, Unfolded protein response, Biophysics, Thermodynamics, Cattle, molecular simulations, Macromolecular crowding
-
6
المؤلفون: Michael Hennig, Andreas Brockmann, Ulrich Ebbinghaus-Kintscher, Mathieu Botte, Nicolas Bocquet, David Gnutt, Alexander K. C. Ulrich, Ricardo Adaixo, Andreas Becker, Ursula Egner, Mohamed Chami, Henning Stahlberg, Denis Bucher, Simon Holton, Vera Puetter
مصطلحات موضوعية: Agonist, TRPV4, Transient receptor potential channel, medicine.drug_class, Chemistry, Cryo-electron microscopy, Mutagenesis, medicine, Biophysics, Gating, Binding site, Ion channel
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e31bf4c6811dc0a3924ed7a8cc3d780
-
7
المؤلفون: Simon Ebbinghaus, Christian Heid, Frank-Gerrit Klärner, Anne Steinhof, Kenny Bravo-Rodriguez, Erich E. Wanker, Tobias Vöpel, Abhishek Sharma, Elsa Sanchez-Garcia, Thomas Schrader, Shivang Vachharajani, David Gnutt, Joseph A. Loo, Gal Bitan, Oluwaseun Fatoba, Michael Nshanian, Gisa Ellrichmann, Sumit Mittal
المصدر: Journal of the American Chemical Society, vol 139, iss 16
Voepel, T; Bravo-Rodriguez, K; Mittal, S; Vachharajani, S; Gnutt, D; Sharma, A; et al.(2017). Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139(16), 5640-5643. doi: 10.1021/jacs.6b11039. UCLA: Retrieved from: http://www.escholarship.org/uc/item/886087d7مصطلحات موضوعية: Bridged-Ring Compounds, Huntington's Disease, 0301 basic medicine, Huntingtin, Chemie, Molecular Dynamics Simulation, Neurodegenerative, Protein aggregation, Biochemistry, Article, Catalysis, Protein Aggregates, 03 medical and health sciences, Exon, Rare Diseases, Colloid and Surface Chemistry, Huntingtin Protein, Humans, 2.1 Biological and endogenous factors, Aetiology, Molecular Structure, Chemistry, Neurosciences, Exons, General Chemistry, Polyglutamine tract, Organophosphates, Brain Disorders, Cell biology, Glutamine, 030104 developmental biology, Chemical Sciences, Toxicity, Hydrophobic and Hydrophilic Interactions
وصف الملف: application/pdf
-
8
المصدر: Molecular BioSystems. 13:2218-2221
مصطلحات موضوعية: 0301 basic medicine, 030102 biochemistry & molecular biology, Osmotic shock, Chemistry, Adaptation, Physiological, Crowding, humanities, 03 medical and health sciences, 030104 developmental biology, Osmotic Pressure, Stress, Physiological, Osmolyte, Extracellular, Biophysics, Animals, Humans, Slow response, Adaptation, Molecular Biology, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e539eb66902969ff5dc6ae9aa544e122
https://doi.org/10.1039/c7mb00432j -
9
المؤلفون: Benedikt König, Fabio Sterpone, Matthias Heyden, Stepan Timr, David Gnutt, Simon Ebbinghaus, Emily Manderfeld, Jonas Ahlers
المساهمون: Max-Planck-Institut für Kohlenforschung (Coal Research), Max-Planck-Gesellschaft, Laboratoire de biochimie théorique [Paris] (LBT (UPR_9080)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut de biologie physico-chimique (IBPC (FR_550)), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Université Paris Diderot - Paris 7 (UPD7)-Institut de biologie physico-chimique (IBPC), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2019, 141 (11), pp.4660-4669. ⟨10.1021/jacs.8b13025⟩مصطلحات موضوعية: Protein Conformation, SOD1, Mutant, Cell, Molecular Dynamics Simulation, 010402 general chemistry, 01 natural sciences, Biochemistry, Catalysis, Superoxide Dismutase-1, Colloid and Surface Chemistry, Enzyme Stability, medicine, Humans, Point Mutation, [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS, chemistry.chemical_classification, Chemistry, Quinary, General Chemistry, 0104 chemical sciences, Amino acid, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, medicine.anatomical_structure, Structural biology, Biophysics, Protein folding, Function (biology), HeLa Cells, Protein Binding
-
10
المؤلفون: David Gnutt, Simon Ebbinghaus, Matthias Heyden
المصدر: Nachrichten aus der Chemie. 64:310-313
مصطلحات موضوعية: General Chemical Engineering, General Chemistry