المؤلفون: Oliver Brylski, Puja Shrestha, Patricia Gnutt, David Gnutt, Jonathan Wolf Mueller, Simon Ebbinghaus

المصدر: Frontiers in Molecular Biosciences, Vol 8 (2021)

مصطلحات موضوعية: PAPS synthase, ATP depletion, in-cell spectroscopy, protein folding stability, alanine scanning, ligand binding, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.790304/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/de9a4c9fe7714359b2b563c3ecbac3e3

المؤلفون: David Gnutt, Linda Sistemich, Simon Ebbinghaus

المصدر: Frontiers in Molecular Biosciences, Vol 6 (2019)

مصطلحات موضوعية: cytomimetic media, protein folding and stability, in-cell spectroscopy, Macromolecular crowding, fast relaxation imaging (FReI), Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmolb.2019.00038/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/f58d130189304f7f9e46b507012a53fb

المؤلفون: Srinivas Niranj Chandrasekaran, Jeanelle Ackerman, Eric Alix, D. Michael Ando, John Arevalo, Melissa Bennion, Nicolas Boisseau, Adriana Borowa, Justin D. Boyd, Laurent Brino, Patrick J. Byrne, Hugo Ceulemans, Carolyn Ch’ng, Beth A. Cimini, Djork-Arne Clevert, Nicole Deflaux, John G Doench, Thierry Dorval, Regis Doyonnas, Vincenza Dragone, Ola Engkvist, Patrick W. Faloon, Briana Fritchman, Florian Fuchs, Sakshi Garg, Tamara J. Gilbert, David Glazer, David Gnutt, Amy Goodale, Jeremy Grignard, Judith Guenther, Yu Han, Zahra Hanifehlou, Santosh Hariharan, Desiree Hernandez, Shane R Horman, Gisela Hormel, Michael Huntley, Ilknur Icke, Makiyo Iida, Christina B. Jacob, Steffen Jaensch, Jawahar Khetan, Maria Kost-Alimova, Tomasz Krawiec, Daniel Kuhn, Charles-Hugues Lardeau, Amanda Lembke, Francis Lin, Kevin D. Little, Kenneth R. Lofstrom, Sofia Lotfi, David J. Logan, Yi Luo, Franck Madoux, Paula A. Marin Zapata, Brittany A. Marion, Glynn Martin, Nicola Jane McCarthy, Lewis Mervin, Lisa Miller, Haseeb Mohamed, Tiziana Monteverde, Elizabeth Mouchet, Barbara Nicke, Arnaud Ogier, Anne-Laure Ong, Marc Osterland, Magdalena Otrocka, Pieter J. Peeters, James Pilling, Stefan Prechtl, Chen Qian, Krzysztof Rataj, David E Root, Sylvie K. Sakata, Simon Scrace, Hajime Shimizu, David Simon, Peter Sommer, Craig Spruiell, Iffat Sumia, Susanne E Swalley, Hiroki Terauchi, Amandine Thibaudeau, Amy Unruh, Jelle Van de Waeter, Michiel Van Dyck, Carlo van Staden, Michał Warchoł, Erin Weisbart, Amélie Weiss, Nicolas Wiest-Daessle, Guy Williams, Shan Yu, Bolek Zapiec, Marek Żyła, Shantanu Singh, Anne E. Carpenter

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0ad294298f87b0d35776a491fba28d7f
https://doi.org/10.1101/2023.03.23.534023

المؤلفون: Nirnay Samanta, Yasser B. Ruiz‐Blanco, Zamira Fetahaj, David Gnutt, Carter Lantz, Joseph A. Loo, Elsa Sanchez‐Garcia, Simon Ebbinghaus

المصدر: Chembiochem : a European journal of chemical biology, vol 23, iss 21

مصطلحات موضوعية: amyotrophic lateral sclerosis, Protein Folding, Bioengineering, Neurodegenerative, Biochemistry, Medicinal and Biomolecular Chemistry, Rare Diseases, Superoxide Dismutase-1, medicinal chemistry, supramolecular ligands, Nanotechnology, 2.1 Biological and endogenous factors, Humans, Aetiology, Molecular Biology, CLR01, Superoxide Dismutase, Organic Chemistry, Amyotrophic Lateral Sclerosis, Neurosciences, Neurodegenerative Diseases, SOD1, Brain Disorders, 5.1 Pharmaceuticals, Neurological, Mutation, Molecular Medicine, Biochemistry and Cell Biology, ALS, Development of treatments and therapeutic interventions, Biologie

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356a4dd55c1acc143b817192e659daac
https://pubmed.ncbi.nlm.nih.gov/36083789

المؤلفون: Simon Ebbinghaus, Stepan Timr, Fabio Sterpone, David Gnutt

المساهمون: Laboratoire de biochimie théorique [Paris] (LBT (UPR_9080)), Institut de biologie physico-chimique (IBPC (FR_550)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Ruhr-Universität Bochum [Bochum], Technische Universität Braunschweig = Technical University of Braunschweig [Braunschweig], This project has received funding from the European Union's Horizon 2020 research andinnovation programme under the Marie Sklodowska-Curie grant agreement No 840395., European Project: 840395,CROWDY, Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)

المصدر: Journal of Physical Chemistry Letters
Journal of Physical Chemistry Letters, 2020, ⟨10.1021/acs.jpclett.0c00699⟩
Journal of Physical Chemistry Letters, American Chemical Society, 2020, ⟨10.1021/acs.jpclett.0c00699⟩
The Journal of Physical Chemistry Letters

مصطلحات موضوعية: macromolecular crowding, Light, Molecular Dynamics Simulation, 010402 general chemistry, 01 natural sciences, thermal stability, Superoxide dismutase, 03 medical and health sciences, Molecular dynamics, Superoxide Dismutase-1, superoxide dismutase 1, Animals, General Materials Science, Physical and Theoretical Chemistry, Bovine serum albumin, 030304 developmental biology, Protein Unfolding, 0303 health sciences, biology, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Chemistry, Serum Albumin, Bovine, mutations, 0104 chemical sciences, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, [SDV.BBM.BP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biophysics, Excluded volume, biology.protein, Unfolded protein response, Biophysics, Thermodynamics, Cattle, molecular simulations, Macromolecular crowding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8a3730390ecb786bb01bfcb18f1193
https://hal.science/hal-02569391

المؤلفون: Michael Hennig, Andreas Brockmann, Ulrich Ebbinghaus-Kintscher, Mathieu Botte, Nicolas Bocquet, David Gnutt, Alexander K. C. Ulrich, Ricardo Adaixo, Andreas Becker, Ursula Egner, Mohamed Chami, Henning Stahlberg, Denis Bucher, Simon Holton, Vera Puetter

مصطلحات موضوعية: Agonist, TRPV4, Transient receptor potential channel, medicine.drug_class, Chemistry, Cryo-electron microscopy, Mutagenesis, medicine, Biophysics, Gating, Binding site, Ion channel

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e31bf4c6811dc0a3924ed7a8cc3d780

المؤلفون: Simon Ebbinghaus, Christian Heid, Frank-Gerrit Klärner, Anne Steinhof, Kenny Bravo-Rodriguez, Erich E. Wanker, Tobias Vöpel, Abhishek Sharma, Elsa Sanchez-Garcia, Thomas Schrader, Shivang Vachharajani, David Gnutt, Joseph A. Loo, Gal Bitan, Oluwaseun Fatoba, Michael Nshanian, Gisa Ellrichmann, Sumit Mittal

المصدر: Journal of the American Chemical Society, vol 139, iss 16
Voepel, T; Bravo-Rodriguez, K; Mittal, S; Vachharajani, S; Gnutt, D; Sharma, A; et al.(2017). Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139(16), 5640-5643. doi: 10.1021/jacs.6b11039. UCLA: Retrieved from: http://www.escholarship.org/uc/item/886087d7

مصطلحات موضوعية: Bridged-Ring Compounds, Huntington's Disease, 0301 basic medicine, Huntingtin, Chemie, Molecular Dynamics Simulation, Neurodegenerative, Protein aggregation, Biochemistry, Article, Catalysis, Protein Aggregates, 03 medical and health sciences, Exon, Rare Diseases, Colloid and Surface Chemistry, Huntingtin Protein, Humans, 2.1 Biological and endogenous factors, Aetiology, Molecular Structure, Chemistry, Neurosciences, Exons, General Chemistry, Polyglutamine tract, Organophosphates, Brain Disorders, Cell biology, Glutamine, 030104 developmental biology, Chemical Sciences, Toxicity, Hydrophobic and Hydrophilic Interactions

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1f6a9aaa51ca50a51c46a561c4c1bf
https://doi.org/10.1021/jacs.6b11039

المؤلفون: Martina Havenith, Eugen Edengeiser, Simon Ebbinghaus, David Gnutt, Oliver Brylski

المصدر: Molecular BioSystems. 13:2218-2221

مصطلحات موضوعية: 0301 basic medicine, 030102 biochemistry & molecular biology, Osmotic shock, Chemistry, Adaptation, Physiological, Crowding, humanities, 03 medical and health sciences, 030104 developmental biology, Osmotic Pressure, Stress, Physiological, Osmolyte, Extracellular, Biophysics, Animals, Humans, Slow response, Adaptation, Molecular Biology, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e539eb66902969ff5dc6ae9aa544e122
https://doi.org/10.1039/c7mb00432j

المؤلفون: Benedikt König, Fabio Sterpone, Matthias Heyden, Stepan Timr, David Gnutt, Simon Ebbinghaus, Emily Manderfeld, Jonas Ahlers

المساهمون: Max-Planck-Institut für Kohlenforschung (Coal Research), Max-Planck-Gesellschaft, Laboratoire de biochimie théorique [Paris] (LBT (UPR_9080)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut de biologie physico-chimique (IBPC (FR_550)), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Université Paris Diderot - Paris 7 (UPD7)-Institut de biologie physico-chimique (IBPC), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2019, 141 (11), pp.4660-4669. ⟨10.1021/jacs.8b13025⟩

مصطلحات موضوعية: Protein Conformation, SOD1, Mutant, Cell, Molecular Dynamics Simulation, 010402 general chemistry, 01 natural sciences, Biochemistry, Catalysis, Superoxide Dismutase-1, Colloid and Surface Chemistry, Enzyme Stability, medicine, Humans, Point Mutation, [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS, chemistry.chemical_classification, Chemistry, Quinary, General Chemistry, 0104 chemical sciences, Amino acid, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, medicine.anatomical_structure, Structural biology, Biophysics, Protein folding, Function (biology), HeLa Cells, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d210677d5c1f8625f7c75460de41f50
https://hal.archives-ouvertes.fr/hal-02360012

المؤلفون: David Gnutt, Simon Ebbinghaus, Matthias Heyden

المصدر: Nachrichten aus der Chemie. 64:310-313

مصطلحات موضوعية: General Chemical Engineering, General Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::526d0bd268590a4aa0151f87858c3418
https://doi.org/10.1002/nadc.20164047296