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1Talazoparib has no clinically relevant effect on QTc interval in patients with advanced solid tumors
المؤلفون: Zev A. Wainberg, RL Moroose, Anna Plotka, Linh Nguyen, Justin Hoffman, David Kanamori, Jayeta Chakrabarti, Adriana Milillo Naraine, Diane Wang
المصدر: Anti-Cancer Drugs
Anti-cancer drugs, vol 30, iss 5مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, RR interval, Medical Biochemistry and Metabolomics, poly(ADP-ribose) polymerase inhibitors, Cardiovascular, QTc study, talazoparib, QT interval, Clinical Reports, Medicinal and Biomolecular Chemistry, Electrocardiography, 03 medical and health sciences, QRS complex, 0302 clinical medicine, Pharmacokinetics, Clinical Research, Heart Rate, QT interval prolongation, Neoplasms, Internal medicine, Heart rate, Humans, Medicine, Pharmacology (medical), In patient, Oncology & Carcinogenesis, cardiovascular diseases, Adverse effect, Pharmacology, business.industry, Corrected qt, Pharmacology and Pharmaceutical Sciences, Middle Aged, Prognosis, Heart Disease, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Cardiology, Phthalazines, Female, business, Follow-Up Studies
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a4a7d43efdbec9c15b024a5a43735f
https://doi.org/10.1097/cad.0000000000000772 -
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المؤلفون: Pamela Melone, Juris P. Simanis, G. Sakuntala Warshamana-Greene, John M. McCarty, Emmanuel N. Dessypris, David Kanamori
المصدر: Experimental Hematology. 34:87-96
مصطلحات موضوعية: Platelet Membrane Glycoprotein IIb, Cancer Research, Cellular differentiation, Antigens, CD34, In Vitro Techniques, Pharmacology, Biology, Models, Biological, Cell Line, Proto-Oncogene Proteins, Genetics, medicine, Humans, Receptors, Cytokine, Phosphotyrosine, Receptor, Molecular Biology, Cells, Cultured, Thrombopoietin, Cell Proliferation, Ploidies, Dose-Response Relationship, Drug, Cell growth, Cell Differentiation, Cell Biology, Hematology, Anagrelide, Cell sorting, Hematopoietic Stem Cells, Biochemistry, Cell culture, embryonic structures, Quinazolines, Interleukin-3, Stem cell, Receptors, Thrombopoietin, Platelet Aggregation Inhibitors, medicine.drug