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1دورية أكاديمية
المؤلفون: Maike Bublitz, Lasse Kjellerup, Karen O'Hanlon Cohrt, Sandra Gordon, Anne Louise Mortensen, Johannes D Clausen, Thomas David Pallin, John Bondo Hansen, Anja Thoe Fuglsang, William Dalby-Brown, Anne-Marie L Winther
المصدر: PLoS ONE, Vol 13, Iss 1, p e0188620 (2018)
وصف الملف: electronic resource
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المؤلفون: Martin Everett, Michael S. Bodnarchuk, Venkatesh Kotha, Nicolas Sprynski, Narender Pottabathini, Lilha Beyria, Paduri Karunakar, Mark William Jones, Toby M G Mullins, Ramesh Ramula, T David Pallin, Sathish Kumar Martha, Jérôme Castandet, Jonathan M Sutton, Marc Lemonnier, Andrew Keith Harlow Forrest, Simon Leiris, David T. Davies, Battu Parusharamulu, Srinivasu Pothukanuri
المصدر: ACS Medicinal Chemistry Letters. 12:217-227
مصطلحات موضوعية: Virtual screening, 010405 organic chemistry, medicine.drug_class, business.industry, Pseudomonas aeruginosa, Organic Chemistry, Antibiotics, Elastase, Virulence, medicine.disease, medicine.disease_cause, 01 natural sciences, Biochemistry, Cystic fibrosis, 0104 chemical sciences, 3. Good health, Microbiology, 010404 medicinal & biomolecular chemistry, Drug Discovery, medicine, Pseudolysin, business, Pathogen
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المؤلفون: Thomas David Pallin, Marc Lemonnier, Stefano Mangani, Martin Everett, Ramakrishna R. Juventhala, Jean Denis Docquier, Maëlle Bayet, Narender Pottabathini, Battu Shankar, Nicolas Sprynski, Ashok Kumar Soodhagani, Gilles Raphy, Jérôme Castandet, Mark William Jones, Juliette Bougnon, Ramesh Pattipati, Alicia Coelho, Clarisse Lozano, Simon Leiris, Neil Jennings, Giulia Cerboni, Manuela Benvenuti, Cecilia Pozzi, David T. Davies, Srinivasu Pothukanuri, Justine Bousquet, Michael C. Cramp, Relangi Sivasubrahmanyam, Filomena De Luca, Magdalena Zalacain
المصدر: 'ACS Infectious Diseases ', vol: 5, pages: 131-140 (2019)
ACS Infectious Diseasesمصطلحات موضوعية: 0301 basic medicine, antibiotic resistance, medicine.drug_class, Clinical effectiveness, efficacy, 030106 microbiology, Antibiotics, Microbial Sensitivity Tests, Carbapenem-resistant enterobacteriaceae, NDM-1, Crystallography, X-Ray, Meropenem, Article, beta-Lactamases, Metallo β lactamase, Microbiology, Inhibitory Concentration 50, Structure-Activity Relationship, 03 medical and health sciences, Antibiotic resistance, Carbapenem Antibiotics, Drug Resistance, Multiple, Bacterial, polycyclic compounds, medicine, Picolinic Acids, meropenem, metallo-β-lactamase inhibitor, VIM-2, Infectious Diseases, business.industry, Enterobacteriaceae Infections, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, Anti-Bacterial Agents, 3. Good health, Carbapenem-Resistant Enterobacteriaceae, 030104 developmental biology, Carbapenems, bacteria, Mobile genetic elements, beta-Lactamase Inhibitors, business, Protein Binding, medicine.drug
وصف الملف: application/pdf
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المؤلفون: David T, Davies, Simon, Leiris, Magdalena, Zalacain, Nicolas, Sprynski, Jérôme, Castandet, Justine, Bousquet, Clarisse, Lozano, Agustina, Llanos, Laethitia, Alibaud, Srinivas, Vasa, Ramesh, Pattipati, Ravindar, Valige, Bhaskar, Kummari, Srinivasu, Pothukanuri, Cyntia, De Piano, Ian, Morrissey, Kirsty, Holden, Peter, Warn, Francesca, Marcoccia, Manuela, Benvenuti, Cecilia, Pozzi, Giusy, Tassone, Stefano, Mangani, Jean-Denis, Docquier, David, Pallin, Richard, Elliot, Marc, Lemonnier, Martin, Everett
المصدر: Journal of medicinal chemistry. 63(24)
مصطلحات موضوعية: Binding Sites, Acinetobacter, Drug Evaluation, Preclinical, Stereoisomerism, Microbial Sensitivity Tests, Octanes, beta-Lactamases, Anti-Bacterial Agents, Molecular Docking Simulation, Mice, Structure-Activity Relationship, Carbapenems, Enterobacteriaceae, Drug Resistance, Bacterial, Animals, beta-Lactamase Inhibitors, Half-Life
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المؤلفون: Nicolas Sprynski, Simon Leiris, Kirsty Holden, Srinivasu Pothukanuri, Martin Everett, Agustina Llanos, Manuela Benvenuti, Srinivas Vasa, David T. Davies, Francesca Marcoccia, Richard Elliot, Magdalena Zalacain, Clarisse Lozano, Peter Warn, David Pallin, Cecilia Pozzi, Justine Bousquet, Ian Morrissey, Marc Lemonnier, Ravindar Valige, Bhaskar Kummari, G. Tassone, Jean Denis Docquier, Stefano Mangani, Jérôme Castandet, Ramesh Pattipati, Laethitia Alibaud, Cyntia De Piano
مصطلحات موضوعية: 0303 health sciences, Carbapenem, biology, Chemistry, Avibactam, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, 01 natural sciences, Meropenem, 0104 chemical sciences, Acinetobacter baumannii, Microbiology, Serine, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, Antibiotic resistance, Drug Discovery, polycyclic compounds, medicine, Molecular Medicine, Structure–activity relationship, Beta-Lactamase Inhibitors, 030304 developmental biology, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d974eab718ab77cc1b0732365a12c9e0
http://hdl.handle.net/11365/1125122 -
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المؤلفون: William Dalby-Brown, Anne-Marie Lund Winther, Johannes D. Clausen, Thomas David Pallin, Anne Louise Mortensen, Karen O'Hanlon Cohrt, Maike Bublitz, John Bondo Hansen, Anja T. Fuglsang, Lasse Kjellerup, Sandra Gordon
المصدر: PLoS ONE
Bublitz, M, Kjellerup, L, Cohrt, K OH, Gordon, S, Mortensen, A L, Clausen, J D, Pallin, T D, Hansen, J B, Fuglsang, A T, Dalby-Brown, W & Winther, A-M L 2018, ' Tetrahydrocarbazoles are a novel class of potent P-type ATPase inhibitors with antifungal activity ', PLOS ONE, vol. 13, no. 1, e0188620 . https://doi.org/10.1371/journal.pone.0188620
PLoS ONE, Vol 13, Iss 1, p e0188620 (2018)مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Adenosine Triphosphatase, Antifungal Agents, ATPase, Cell Membranes, lcsh:Medicine, Yeast and Fungal Models, Crystallography, X-Ray, Pathology and Laboratory Medicine, Biochemistry, Membrane Potentials, chemistry.chemical_compound, Adenosine Triphosphate, ATP hydrolysis, Chemical reactions, Microbial Physiology, Medicine and Health Sciences, Enzyme Inhibitors, lcsh:Science, Candida, Fungal Pathogens, Multidisciplinary, Crystallography, biology, Molecular Structure, Antimicrobials, Hydrolysis, Physics, Microbial Growth and Development, Eukaryota, Drugs, Hep G2 Cells, Condensed Matter Physics, 3. Good health, Enzymes, Chemistry, Experimental Organism Systems, Medical Microbiology, Physical Sciences, Crystal Structure, Saccharomyces Cerevisiae, Pathogens, Cellular Structures and Organelles, medicine.drug, Research Article, Fungal Growth, SERCA, Stereochemistry, 030106 microbiology, Carbazoles, Microbial Sensitivity Tests, Mycology, Research and Analysis Methods, Microbiology, 03 medical and health sciences, Saccharomyces, Model Organisms, Microbial Control, medicine, Humans, Candida Albicans, Solid State Physics, Homology modeling, Binding site, Microbial Pathogens, Pharmacology, Antifungals, lcsh:R, Organisms, Fungi, Phosphatases, Biology and Life Sciences, Proteins, Cell Biology, Adenosine, Yeast, 030104 developmental biology, chemistry, P-type ATPases, biology.protein, P-type ATPase, Enzymology, lcsh:Q, Drug Screening Assays, Antitumor, Adenosine triphosphate, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Gill Matthew Iain Andrew, Ines Warner, Peter Ward, Jonathan R. Seckl, Hazel Joan Dyke, Brian R. Walker, Michael F. Greaney, Andy Vinter, Scott P. Webster, Karen Sooy, Margaret Binnie, Kirsty M.M. McConnell, T. David Pallin
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:3265-3271
مصطلحات موضوعية: Models, Molecular, Clinical Biochemistry, Tetrazoles, Pharmaceutical Science, Dehydrogenase, Biochemistry, Isozyme, Article, Mice, In vivo, 11β-hydroxysteroid dehydrogenase type 1, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Drug Discovery, Animals, Humans, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, biology, Chemistry, Organic Chemistry, In vitro, Enzyme, Enzyme inhibitor, biology.protein, Microsome, Molecular Medicine, hormones, hormone substitutes, and hormone antagonists
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المؤلفون: Scott P. Webster, Thomas David Pallin
المصدر: Expert Opinion on Therapeutic Patents. 17:1407-1422
مصطلحات موضوعية: Pharmacology, Genetically modified mouse, medicine.medical_specialty, biology, Adipose tissue, General Medicine, medicine.disease, Endocrinology, 11β-hydroxysteroid dehydrogenase type 1, Ageing, Diabetes mellitus, Internal medicine, Drug Discovery, medicine, biology.protein, Hydroxysteroid dehydrogenase, Metabolic syndrome, Cognitive decline, hormones, hormone substitutes, and hormone antagonists
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المؤلفون: T. David Pallin, Mark Bradley, Peter J May, David C. Harrowven
المصدر: Tetrahedron Letters. 41:1627-1630
مصطلحات موضوعية: chemistry.chemical_classification, Aqueous solution, fungi, Organic Chemistry, technology, industry, and agriculture, food and beverages, Thioester, Biochemistry, Combinatorial chemistry, Merrifield resin, chemistry.chemical_compound, Solid-phase synthesis, stomatognathic system, chemistry, Sodium iodide, Drug Discovery, Organic chemistry, Thioamide
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المؤلفون: Paolo Botti, and T. David Pallin, James P. Tam
المصدر: Journal of the American Chemical Society. 118:10018-10024
مصطلحات موضوعية: chemistry.chemical_classification, Sodium periodate, Stereochemistry, Thiazolidine, Peptide, General Chemistry, Biochemistry, Aldehyde, Tautomer, Catalysis, Cyclic peptide, chemistry.chemical_compound, Colloid and Surface Chemistry, chemistry, Amide, Intramolecular force
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::831ff6d9c3eff5a257aad905d0f580a3
https://doi.org/10.1021/ja954278g
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