المؤلفون: Murphy CS; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine, University of Maine Graduate School of Biomedical Science and Engineering, Orono, ME, USA., DeMambro VE; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine, University of Maine Graduate School of Biomedical Science and Engineering, Orono, ME, USA., Fadel S; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of New England, Biddeford, ME, USA., Fairfield H; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine, University of Maine Graduate School of Biomedical Science and Engineering, Orono, ME, USA.; Tufts University School of Medicine, Boston MA, USA., Garter CA; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine, University of Maine Graduate School of Biomedical Science and Engineering, Orono, ME, USA., Rodriguez P; University of Vermont, Burlington, VT, USA., Qiang YW; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA., Vary CPH; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine, University of Maine Graduate School of Biomedical Science and Engineering, Orono, ME, USA.; Tufts University School of Medicine, Boston MA, USA., Reagan MR; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine, University of Maine Graduate School of Biomedical Science and Engineering, Orono, ME, USA.; Tufts University School of Medicine, Boston MA, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 14. Date of Electronic Publication: 2024 Mar 14.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: DeMambro VE; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME, USA., Tian L; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA., Karthik V; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME, USA., Rosen CJ; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; Tufts University School of Medicine, Tufts University, Boston, MA, USA.; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME, USA., Guntur AR; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; Tufts University School of Medicine, Tufts University, Boston, MA, USA.; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME, USA.

المصدر: Bone reports [Bone Rep] 2023 Jul 24; Vol. 19, pp. 101705. Date of Electronic Publication: 2023 Jul 24 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101646176 Publication Model: eCollection Cited Medium: Print ISSN: 2352-1872 (Print) Linking ISSN: 23521872 NLM ISO Abbreviation: Bone Rep Subsets: PubMed not MEDLINE

المؤلفون: Martinez ME; Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, ME, 04074, USA., Duarte CW; Center for Outcomes Research and Evaluation, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, ME, 04074, USA.; Graduate School for Biomedical Science and Engineering, University of Maine, Orono, ME, 04469, USA., Stohn JP; Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, ME, 04074, USA., Karaczyn A; Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, ME, 04074, USA., Wu Z; Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, ME, 04074, USA., DeMambro VE; Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, ME, 04074, USA., Hernandez A; Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, ME, 04074, USA. hernaa@mmc.org.; Graduate School for Biomedical Science and Engineering, University of Maine, Orono, ME, 04469, USA. hernaa@mmc.org.; Department of Medicine, Tufts University School of Medicine, Boston, MA, USA. hernaa@mmc.org.

المصدر: Molecular psychiatry [Mol Psychiatry] 2020 May; Vol. 25 (5), pp. 939-950. Date of Electronic Publication: 2018 Oct 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE

مواضيع طبية MeSH: Behavior, Animal/*physiology , Epigenesis, Genetic/*physiology , Gene Expression/*physiology , Germ Cells/*physiology , Hypothalamus/*metabolism , Inheritance Patterns/*physiology , Thyroid Hormones/*physiology, Animals ; Brain/growth & development ; CpG Islands/genetics ; DNA Methylation ; Female ; Iodide Peroxidase/genetics ; Male ; Mice ; Mutation ; Reelin Protein

المؤلفون: Xi G; Department of Medicine UNC School of Medicine Chapel Hill, North Carolina., Demambro VE; Maine Medical Center Research Institute, Scarborough, Maine., D'Costa S; Department of Medicine UNC School of Medicine Chapel Hill, North Carolina., Xia SK; Department of Medicine UNC School of Medicine Chapel Hill, North Carolina., Cox ZC; Department of Medicine UNC School of Medicine Chapel Hill, North Carolina., Rosen CJ; Maine Medical Center Research Institute, Scarborough, Maine., Clemmons DR; Department of Medicine UNC School of Medicine Chapel Hill, North Carolina.

المصدر: Endocrinology [Endocrinology] 2020 Apr 01; Vol. 161 (4).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

مواضيع طبية MeSH: Bone Density/*drug effects , Carrier Proteins/*metabolism , Cell Differentiation/*drug effects , Cytokines/*metabolism , Estradiol/*pharmacology , Insulin-Like Growth Factor Binding Protein 2/*metabolism , Osteoblasts/*drug effects, Animals ; Cancellous Bone/drug effects ; Cancellous Bone/metabolism ; Female ; Insulin-Like Growth Factor Binding Protein 2/genetics ; Male ; Mice ; Mice, Knockout ; Osteoblasts/metabolism ; Osteogenesis/drug effects ; Phosphorylation/drug effects ; Sex Factors

المؤلفون: Fujiwara M; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, Maine 04074., Tian L; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine 04074., Le PT; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, Maine 04074., DeMambro VE; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, Maine 04074., Becker KA; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, Maine 04074., Rosen CJ; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, Maine 04074.; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine 04074., Guntur AR; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine 04074 guntua@mmc.org.

المصدر: The Journal of biological chemistry [J Biol Chem] 2019 Aug 23; Vol. 294 (34), pp. 12683-12694. Date of Electronic Publication: 2019 Jul 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis* , Mitophagy* , Oxidative Phosphorylation*, Adipogenesis/*genetics , Mitochondria/*metabolism , Proto-Oncogene Proteins c-bcl-2/*metabolism, Animals ; Cells, Cultured ; Mice ; Mice, Inbred C3H ; Mice, Inbred C57BL

المؤلفون: Maridas DE; Maine Medical Center Research Institute, Scarborough, Maine, USA.; Harvard School of Dental Medicine, Boston, Massachusetts, USA; and., Rendina-Ruedy E; Maine Medical Center Research Institute, Scarborough, Maine, USA., Helderman RC; Maine Medical Center Research Institute, Scarborough, Maine, USA., DeMambro VE; Maine Medical Center Research Institute, Scarborough, Maine, USA., Brooks D; Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Guntur AR; Maine Medical Center Research Institute, Scarborough, Maine, USA., Lanske B; Harvard School of Dental Medicine, Boston, Massachusetts, USA; and., Bouxsein ML; Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Rosen CJ; Maine Medical Center Research Institute, Scarborough, Maine, USA.

المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2019 Feb; Vol. 33 (2), pp. 2885-2898. Date of Electronic Publication: 2018 Oct 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

مواضيع طبية MeSH: Adipocytes/*cytology , Bone Resorption/*drug therapy , Lipolysis/*drug effects , Mesenchymal Stem Cells/*cytology , Osteoblasts/*cytology , Parathyroid Hormone/*pharmacology , Stem Cells/*cytology, Adipocytes/drug effects ; Adipocytes/metabolism ; Adipogenesis ; Animals ; Bone Resorption/metabolism ; Bone Resorption/pathology ; Caloric Restriction ; Cell Differentiation ; Cells, Cultured ; Female ; Mesenchymal Stem Cells/drug effects ; Mesenchymal Stem Cells/metabolism ; Mice ; Mice, Inbred C57BL ; Osteoblasts/drug effects ; Osteoblasts/metabolism ; Osteogenesis ; Stem Cells/drug effects ; Stem Cells/metabolism

المؤلفون: Guntur AR; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, ME, USA., Gerencser AA; Department of Biological and Pharmaceutical Sciences, Touro University California College of Pharmacy, Vallejo, CA, USA.; Buck Institute for Research on Aging, Novato, CA, USA., Le PT; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, ME, USA., DeMambro VE; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, ME, USA., Bornstein SA; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, ME, USA., Mookerjee SA; Department of Biological and Pharmaceutical Sciences, Touro University California College of Pharmacy, Vallejo, CA, USA.; Buck Institute for Research on Aging, Novato, CA, USA., Maridas DE; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, ME, USA.; Harvard School of Dental Medicine, Boston, MA, USA., Clemmons DE; University of North Carolina, Chapel Hill, NC, USA., Brand MD; Department of Biological and Pharmaceutical Sciences, Touro University California College of Pharmacy, Vallejo, CA, USA.; Buck Institute for Research on Aging, Novato, CA, USA., Rosen CJ; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, ME, USA.

المصدر: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2018 Jun; Vol. 33 (6), pp. 1052-1065. Date of Electronic Publication: 2018 Mar 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Bone and Mineral Research Country of Publication: United States NLM ID: 8610640 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-4681 (Electronic) Linking ISSN: 08840431 NLM ISO Abbreviation: J Bone Miner Res Subsets: MEDLINE

مواضيع طبية MeSH: Glycolysis* , Oxidative Phosphorylation*, Adenosine Triphosphate/*biosynthesis , Adipocytes/*metabolism , Osteoblasts/*metabolism, 3T3-L1 Cells ; Adipocytes/cytology ; Animals ; Cell Differentiation ; Cell Respiration ; Energy Metabolism ; Gene Expression Regulation ; Glucose/metabolism ; Lactates/metabolism ; Membrane Potential, Mitochondrial ; Mice ; Mitochondria/metabolism ; Osteoblasts/cytology

المؤلفون: Carvalho AL; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, Maine.; Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil., DeMambro VE; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, Maine., Guntur AR; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, Maine., Le P; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, Maine., Nagano K; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Harvard University, Boston, Massachusetts., Baron R; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Harvard University, Boston, Massachusetts., de Paula FJA; Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil., Motyl KJ; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, Maine.; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine.

المصدر: Journal of cellular physiology [J Cell Physiol] 2018 Feb; Vol. 233 (2), pp. 1585-1600. Date of Electronic Publication: 2017 Aug 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4652 (Electronic) Linking ISSN: 00219541 NLM ISO Abbreviation: J Cell Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Body Composition* , Bone Remodeling* , Diet, High-Fat* , Streptozocin*, Blood Glucose/*metabolism , Diabetes Mellitus, Experimental/*diet therapy , Diabetes Mellitus, Type 1/*diet therapy , Fatty Acids/*administration & dosage , Osteoporosis/*prevention & control, Adiposity ; Animals ; Biomarkers/blood ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/chemically induced ; Diabetes Mellitus, Experimental/physiopathology ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/chemically induced ; Diabetes Mellitus, Type 1/physiopathology ; Insulin/blood ; Ketones/blood ; Male ; Mice, Inbred C57BL ; Osteoporosis/blood ; Osteoporosis/chemically induced ; Osteoporosis/physiopathology ; Time Factors ; Weight Loss

المؤلفون: Maridas DE; Maine Medical Center Research Institute, Scarborough, Maine 04074., DeMambro VE; Maine Medical Center Research Institute, Scarborough, Maine 04074., Le PT; Maine Medical Center Research Institute, Scarborough, Maine 04074., Mohan S; Veterans Affairs Loma Linda Healthcare System, Loma Linda, California 92357., Rosen CJ; Maine Medical Center Research Institute, Scarborough, Maine 04074.

المصدر: Endocrinology [Endocrinology] 2017 Oct 01; Vol. 158 (10), pp. 3488-3500.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

مواضيع طبية MeSH: Body Fat Distribution*, Adipogenesis/*genetics , Adipose Tissue, White/*metabolism , Insulin-Like Growth Factor Binding Protein 4/*genetics, Absorptiometry, Photon ; Adipocytes ; Adipose Tissue/metabolism ; Adipose Tissue/pathology ; Adipose Tissue, White/pathology ; Animals ; Blotting, Western ; Cells, Cultured ; Diet, High-Fat ; Female ; Gene Expression Profiling ; Male ; Mesenchymal Stem Cells ; Mice ; Mice, Knockout ; Obesity/genetics ; Obesity/metabolism ; Ovariectomy ; Phenotype ; Reverse Transcriptase Polymerase Chain Reaction ; Sex Factors

المؤلفون: Liu P; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Ji Y; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; School and Hospital of Stomatology, Wuhan University, and Key Laboratory of Oral Biomedicine, Ministry of Education, Wuhan, Hubei 430079, China., Yuen T; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Rendina-Ruedy E; Maine Medical Center Research Institute, Scarborough, Maine 04074, USA., DeMambro VE; Maine Medical Center Research Institute, Scarborough, Maine 04074, USA., Dhawan S; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Abu-Amer W; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Izadmehr S; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Zhou B; Department of Biomedical Engineering, Columbia University, New York, New York 10027, USA., Shin AC; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Latif R; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Thangeswaran P; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Gupta A; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Li J; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Shnayder V; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Robinson ST; Department of Biomedical Engineering, Columbia University, New York, New York 10027, USA., Yu YE; Department of Biomedical Engineering, Columbia University, New York, New York 10027, USA., Zhang X; Department of Biomedical Engineering, Columbia University, New York, New York 10027, USA., Yang F; Department of Biomedical Engineering, Columbia University, New York, New York 10027, USA., Lu P; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Zhou Y; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Zhu LL; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Oberlin DJ; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Davies TF; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Reagan MR; Maine Medical Center Research Institute, Scarborough, Maine 04074, USA., Brown A; Maine Medical Center Research Institute, Scarborough, Maine 04074, USA., Kumar TR; Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA., Epstein S; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Iqbal J; Pathology Service, Greater Los Angeles Veterans Affairs Medical Center, Los Angeles, California 90073, USA., Avadhani NG; Deparment of Animal Biology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania 19104, USA., New MI; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Molina H; Proteomics Resource Center, Rockefeller University, New York, New York 10065, USA., van Klinken JB; Department of Human Genetics and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2311 EZ Leiden, The Netherlands., Guo EX; Department of Biomedical Engineering, Columbia University, New York, New York 10027, USA., Buettner C; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Haider S; Department of Pharmaceutical and Biological Chemistry, University College London School of Pharmacy, London WC1N 1AX, UK., Bian Z; School and Hospital of Stomatology, Wuhan University, and Key Laboratory of Oral Biomedicine, Ministry of Education, Wuhan, Hubei 430079, China., Sun L; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Rosen CJ; Maine Medical Center Research Institute, Scarborough, Maine 04074, USA., Zaidi M; Department of Medicine, and Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

المصدر: Nature [Nature] 2017 Jun 01; Vol. 546 (7656), pp. 107-112. Date of Electronic Publication: 2017 May 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Adiposity*/drug effects , Thermogenesis*/drug effects, Adipose Tissue/*metabolism , Follicle Stimulating Hormone, beta Subunit/*antagonists & inhibitors, Adipocytes/drug effects ; Adipocytes/metabolism ; Adipose Tissue/drug effects ; Adipose Tissue, Beige/drug effects ; Adipose Tissue, Beige/metabolism ; Adipose Tissue, White/drug effects ; Adipose Tissue, White/metabolism ; Animals ; Antibodies/immunology ; Antibodies/pharmacology ; Diet, High-Fat/adverse effects ; Female ; Follicle Stimulating Hormone, beta Subunit/immunology ; Haploinsufficiency ; Male ; Mice ; Mitochondria/drug effects ; Mitochondria/metabolism ; Obesity/drug therapy ; Obesity/prevention & control ; Osteoporosis/drug therapy ; Ovariectomy ; Oxygen Consumption/drug effects ; Receptors, FSH/antagonists & inhibitors ; Receptors, FSH/genetics ; Receptors, FSH/metabolism ; Uncoupling Protein 1/biosynthesis